JP2010530372A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010530372A5 JP2010530372A5 JP2010512358A JP2010512358A JP2010530372A5 JP 2010530372 A5 JP2010530372 A5 JP 2010530372A5 JP 2010512358 A JP2010512358 A JP 2010512358A JP 2010512358 A JP2010512358 A JP 2010512358A JP 2010530372 A5 JP2010530372 A5 JP 2010530372A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- group
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94349407P | 2007-06-12 | 2007-06-12 | |
| US60/943,494 | 2007-06-12 | ||
| PCT/US2008/066766 WO2008154642A2 (en) | 2007-06-12 | 2008-06-12 | Antibacterial agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014094451A Division JP2014177468A (ja) | 2007-06-12 | 2014-05-01 | 抗菌剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010530372A JP2010530372A (ja) | 2010-09-09 |
| JP2010530372A5 true JP2010530372A5 (enExample) | 2011-07-14 |
| JP5539864B2 JP5539864B2 (ja) | 2014-07-02 |
Family
ID=39816683
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010512358A Expired - Fee Related JP5539864B2 (ja) | 2007-06-12 | 2008-06-12 | 抗菌剤 |
| JP2014094451A Pending JP2014177468A (ja) | 2007-06-12 | 2014-05-01 | 抗菌剤 |
| JP2016231270A Pending JP2017081931A (ja) | 2007-06-12 | 2016-11-29 | 抗菌剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014094451A Pending JP2014177468A (ja) | 2007-06-12 | 2014-05-01 | 抗菌剤 |
| JP2016231270A Pending JP2017081931A (ja) | 2007-06-12 | 2016-11-29 | 抗菌剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20100190766A1 (enExample) |
| EP (2) | EP2170814B1 (enExample) |
| JP (3) | JP5539864B2 (enExample) |
| CN (2) | CN107021895A (enExample) |
| CA (2) | CA2691987C (enExample) |
| ES (1) | ES2602615T3 (enExample) |
| TW (4) | TW201716375A (enExample) |
| WO (1) | WO2008154642A2 (enExample) |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8895745B2 (en) | 2006-12-22 | 2014-11-25 | Astex Therapeutics Limited | Bicyclic heterocyclic compounds as FGFR inhibitors |
| CA2672213C (en) | 2006-12-22 | 2016-02-16 | Astex Therapeutics Limited | Bicyclic amine derivatives as protein tyrosine kinase inhibitors |
| EP2170814B1 (en) * | 2007-06-12 | 2016-08-17 | Achaogen, Inc. | Antibacterial agents |
| GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
| GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
| US20110092554A1 (en) * | 2007-11-19 | 2011-04-21 | Richard Chesworth | 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders |
| KR20100135711A (ko) | 2007-12-20 | 2010-12-27 | 엔비보 파마슈티칼즈, 인코퍼레이티드 | 사중치환된 벤젠 |
| JP2011512359A (ja) | 2008-02-14 | 2011-04-21 | アミラ ファーマシューティカルズ，インク． | プロスタグランジンｄ２受容体のアンタゴニストとしての環式ジアリールエーテル化合物 |
| JP2011518130A (ja) | 2008-04-02 | 2011-06-23 | アミラ ファーマシューティカルズ，インク． | プロスタグランジンｄ２受容体のアミノアルキルフェニルアンタゴニスト |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| ES2408932T3 (es) * | 2008-06-25 | 2013-06-24 | Merck Sharp & Dohme Corp. | Síntesis y uso de agentes antibacterianos heterocíclicos |
| MX2010014172A (es) | 2008-07-03 | 2011-02-22 | Amira Pharmaceuticals Inc | Antagonistas de receptores de prostaglandina d2. |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| US8372885B2 (en) * | 2008-09-17 | 2013-02-12 | Novartis Ag | Organic compounds and their uses |
| US8383654B2 (en) | 2008-11-17 | 2013-02-26 | Panmira Pharmaceuticals, Llc | Heterocyclic antagonists of prostaglandin D2 receptors |
| GB0906472D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| GB0906470D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| WO2011005355A1 (en) * | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| FR2950056B1 (fr) | 2009-09-17 | 2011-08-26 | Galderma Res & Dev | Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique |
| FR2950057B1 (fr) | 2009-09-17 | 2011-08-26 | Galderma Res & Dev | Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique |
| EA201270568A1 (ru) | 2009-10-16 | 2012-11-30 | Риб-Экс Фармасьютикалз, Инк. | Антимикробные композиции и способы их получения и применения |
| MY176900A (en) | 2009-10-16 | 2020-08-26 | Rib X Pharmaceuticals Inc | Antimicrobial compounds and methods of making and using the same |
| DK2488525T3 (en) | 2009-10-16 | 2018-08-06 | Melinta Therapeutics Inc | ANTIMICROBIAL COMPOUNDS AND PROCEDURES FOR PREPARING AND USING THEREOF |
| KR20120115989A (ko) | 2010-01-06 | 2012-10-19 | 판미라 파마슈티칼스, 엘엘씨 | Ｄｐ2 길항제 및 이의 용도 |
| TWI543961B (zh) * | 2010-04-20 | 2016-08-01 | 大正製藥股份有限公司 | Novel hydroxamic acid derivatives |
| US8835472B2 (en) * | 2010-09-02 | 2014-09-16 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| WO2012031298A2 (en) | 2010-09-03 | 2012-03-08 | Duke University | Ethynylbenzene derivatives |
| BR112013011693A2 (pt) * | 2010-11-10 | 2016-08-09 | Achaogen Inc | derivados de ácido hidroxâmico e seu uso no tratamento de infecções por bactérias |
| CN109053695A (zh) | 2011-04-15 | 2018-12-21 | 梅琳塔治疗公司 | 抗微生物化合物及制备和使用所述化合物的方法 |
| UY34305A (es) | 2011-09-01 | 2013-04-30 | Novartis Ag | Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar |
| TW201315710A (zh) | 2011-09-12 | 2013-04-16 | Achaogen Inc | Ｎ－（（ｓ）－３－胺基－１－（羥胺基）－３－甲基－１－酮基丁－２－基）－４－（（（１ｒ，２ｒ）－２－（羥甲基）環丙基）丁－１，３－二炔基）苯甲醯胺之多晶型 |
| CN102603690A (zh) * | 2012-01-17 | 2012-07-25 | 凯莱英医药集团（天津）股份有限公司 | 一种一锅法制备四氢吡喃-4-甲酸及其衍生物的方法 |
| UA116534C2 (uk) | 2012-02-17 | 2018-04-10 | Мілленніум Фармасьютікалз, Інк. | Піразолопіримідинілові інгібітори убіквітинактивуючого ферменту |
| WO2013170030A1 (en) * | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| US9196844B2 (en) * | 2012-06-01 | 2015-11-24 | Semiconductor Energy Laboratory Co., Ltd. | Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device |
| US9073921B2 (en) | 2013-03-01 | 2015-07-07 | Novartis Ag | Salt forms of bicyclic heterocyclic derivatives |
| WO2014165075A1 (en) | 2013-03-12 | 2014-10-09 | Achaogen, Inc. | Antibacterial agents |
| ES2728336T3 (es) | 2013-03-15 | 2019-10-23 | Fujifilm Toyama Chemical Co Ltd | Nuevo derivado de ácido hidroxámico o sal del mismo |
| GB201307233D0 (en) * | 2013-04-22 | 2013-05-29 | Vib Vzw | Compounds and uses thereof |
| EA032577B1 (ru) | 2013-07-02 | 2019-06-28 | Милленниум Фармасьютикалз, Инк. | Гетероарильные соединения, пригодные в качестве ингибиторов sumo-активирующего фермента |
| EP3041354A4 (en) | 2013-08-16 | 2017-06-14 | Duke University | Substituted hydroxamic acid compounds |
| US9908851B2 (en) | 2013-08-16 | 2018-03-06 | Duke University | 2-piperidinyl substituted N,3-dihydroxybutanamides |
| WO2015024021A2 (en) | 2013-08-16 | 2015-02-19 | Duke University | Antibacterial compounds |
| MX2016003046A (es) | 2013-09-09 | 2016-09-08 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. |
| US10106543B2 (en) | 2013-09-09 | 2018-10-23 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| WO2015056799A1 (ja) * | 2013-10-18 | 2015-04-23 | 大正製薬株式会社 | ヒドロキサム酸誘導体 |
| JP2016210682A (ja) * | 2013-10-18 | 2016-12-15 | 大正製薬株式会社 | ヒドロキサム酸誘導体 |
| JP2016210683A (ja) * | 2013-10-18 | 2016-12-15 | 大正製薬株式会社 | ヒドロキサム酸誘導体 |
| ES2666130T3 (es) | 2013-12-19 | 2018-05-03 | Idorsia Pharmaceuticals Ltd | Derivados antibacterianos de 1H-indazol y 1H-indol |
| US9539305B1 (en) | 2014-03-14 | 2017-01-10 | Fleurir Abx Llc | Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof |
| KR20170005105A (ko) * | 2014-05-16 | 2017-01-11 | 액테리온 파마슈티칼 리미티드 | 항균성 퀴나졸린-４(３ｈ)-온 유도체 |
| WO2015192078A1 (en) * | 2014-06-12 | 2015-12-17 | Cedars-Sinai Medical Center | Compositions and methods for treating cancers |
| RS59474B1 (sr) | 2014-07-01 | 2019-12-31 | Millennium Pharm Inc | Heteroarilna jedinjenja koja su korisna kao inhibitori sumo-aktivirajućeg enzima |
| RU2017112303A (ru) | 2014-09-12 | 2018-10-12 | Тояма Кемикал Ко., Лтд. | Способ применения комбинации нового производного гидроксамовой кислоты и антибактериального вещества |
| AU2015316401A1 (en) | 2014-09-12 | 2017-04-06 | Fujifilm Toyama Chemical Co., Ltd. | Novel pharmaceutical composition containing hydroxamic acid derivative or salt thereof |
| CN104327140B (zh) * | 2014-10-11 | 2016-06-15 | 吉首大学 | 噁唑烷酮-腺苷型多靶点抗菌化合物及其制法和用途 |
| CN104341476A (zh) * | 2014-10-11 | 2015-02-11 | 吉首大学 | 利奈唑胺-肌苷型多靶点抗菌化合物及其制法和用途 |
| CN104231024B (zh) * | 2014-10-11 | 2016-06-15 | 吉首大学 | 噁二唑-肌苷型化合物作为TyrRS抑制剂及其制法和用途 |
| CN104262433B (zh) * | 2014-10-11 | 2016-06-15 | 吉首大学 | 噁二唑-腺苷型化合物作为TyrRS抑制剂及其制法和用途 |
| CN104341475A (zh) * | 2014-10-11 | 2015-02-11 | 吉首大学 | 利奈唑胺-腺苷型多靶点抗菌化合物及其制法和用途 |
| CN105777464B (zh) * | 2014-12-26 | 2020-09-29 | 中国科学院上海药物研究所 | 异羟肟酸衍生物及其制备方法和应用 |
| JP6208161B2 (ja) | 2015-02-06 | 2017-10-04 | 信越化学工業株式会社 | 非対称共役ジイン化合物の製造方法及びこれを用いたｚ，ｚ−共役ジエン化合物の製造方法 |
| JP2018507881A (ja) | 2015-03-11 | 2018-03-22 | メリンタ セラピューティクス，インコーポレイテッド | 抗微生物化合物ならびにこれらを作製および使用する方法 |
| WO2017083434A1 (en) | 2015-11-09 | 2017-05-18 | Forge Therapeutics, Inc. | Pyrone based compounds for treating bacterial infections |
| EP3374350B1 (en) | 2015-11-09 | 2022-01-05 | Forge Therapeutics, Inc. | Hydroxypyridinone and hydroxypyrimidinone based compounds for treating bacterial infections |
| AU2016367510A1 (en) * | 2015-12-08 | 2018-06-07 | Glaxosmithkline Intellectual Property Development Limited | Substituted benzazinones as antibacterial compounds |
| CN105669750B (zh) * | 2016-03-01 | 2018-04-03 | 中国医学科学院医药生物技术研究所 | 新型锌离子螯合剂及其制备和在抗革兰氏阴性菌感染中的应用 |
| MA43811A (fr) * | 2016-03-07 | 2018-11-28 | Merck Sharp & Dohme | Composés d'arylmonobactame bicycliques et leurs méthodes d'utilisation pour le traitement des infections bactériennes |
| EP3426674A4 (en) | 2016-03-09 | 2019-08-14 | Blade Therapeutics, Inc. | CYCLIC KETO AMID COMPOUNDS AS CALPAIN MODULATORS AND METHOD FOR THE PRODUCTION AND USE THEREOF |
| RU2746850C2 (ru) * | 2016-04-18 | 2021-04-21 | Виворион Терапьютикс Аг | Новые ингибиторы меприна альфа и бета |
| JP7012289B2 (ja) * | 2016-04-25 | 2022-02-14 | デューク ユニバーシティ | ベンゾイルグリシン誘導体およびその作製および使用の方法 |
| EP3452479A1 (en) | 2016-05-06 | 2019-03-13 | Melinta Therapeutics, Inc. | Antimicrobials and methods of making and using same |
| AR108864A1 (es) | 2016-06-23 | 2018-10-03 | Achaogen Inc | Agentes antibacterianos |
| AU2017292646A1 (en) | 2016-07-05 | 2019-02-07 | Blade Therapeutics, Inc. | Calpain modulators and therapeutic uses thereof |
| KR20190063473A (ko) | 2016-09-28 | 2019-06-07 | 블레이드 테라퓨틱스, 인크. | 칼페인 조정자 및 그 치료학적 용도 |
| US11406617B2 (en) * | 2016-12-23 | 2022-08-09 | Intervet Inc. | Compounds for the treatment of bovine or swine respiratory disease |
| MX388647B (es) | 2016-12-23 | 2025-03-20 | Intervet Int Bv | Compuestos utiles para el tratamiento de una infeccion por mannheimia haemolytica o histophilus somni. |
| MX2021011775A (es) | 2017-04-26 | 2023-01-10 | Basilea Pharm Int Ag | Procesos para la preparacion de furazanobencimidazoles y formas cristalinas de estos. |
| US20200095236A1 (en) * | 2017-05-10 | 2020-03-26 | Forge Therapeutics, Inc. | Antibacterial compounds |
| WO2018208985A2 (en) | 2017-05-10 | 2018-11-15 | Forge Therapeutics, Inc. | Antibacterial compounds |
| CA3070427A1 (en) * | 2017-07-27 | 2019-01-31 | BioMendics, LLC | Substituted tolans for the modulation of microbial colonization |
| CN111511723A (zh) * | 2017-08-21 | 2020-08-07 | 米可如比奥提克斯有限公司 | 用作抗菌剂的代谢稳定的n-酰基氨基噁二唑 |
| US11498909B2 (en) | 2018-02-10 | 2022-11-15 | Kbp Biosciences Co., Ltd. | Compound acting as antibiotics |
| WO2019178129A1 (en) | 2018-03-13 | 2019-09-19 | Shire Human Genetic Therapies, Inc. | Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof |
| WO2020061103A1 (en) | 2018-09-18 | 2020-03-26 | Nikang Therapeutics, Inc. | Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors |
| JP7495395B2 (ja) | 2018-09-20 | 2024-06-04 | ブラックスミス メディシンズ，インク． | 抗菌性化合物 |
| CN112969687B (zh) | 2018-10-30 | 2024-08-23 | 吉利德科学公司 | 作为α4β7整合素抑制剂的喹啉衍生物 |
| ES3003232T3 (en) | 2018-10-30 | 2025-03-10 | Gilead Sciences Inc | Compounds for inhibition of alpha4beta7 integrin |
| ES2987796T3 (es) | 2018-10-30 | 2024-11-18 | Gilead Sciences Inc | Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias |
| CA3114240C (en) | 2018-10-30 | 2023-09-05 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| US20220081421A1 (en) * | 2018-11-14 | 2022-03-17 | Forge Therapeutics, Inc. | Antibacterial compounds |
| JPWO2020105660A1 (ja) * | 2018-11-21 | 2021-09-30 | 大正製薬株式会社 | 新規イミダゾール誘導体 |
| CN114222730B (zh) | 2019-08-14 | 2024-09-10 | 吉利德科学公司 | 用于抑制α4β7整合素的化合物 |
| WO2021055589A1 (en) | 2019-09-18 | 2021-03-25 | Shire Human Genetic Therapies, Inc. | Heteroaryl plasma kallikrein inhibitors |
| PT4031547T (pt) | 2019-09-18 | 2024-08-27 | Takeda Pharmaceuticals Co | Inibidores de calicreína plasmática e utilizações dos mesmos |
| CN110563611B (zh) * | 2019-09-19 | 2021-02-02 | 中国医学科学院医药生物技术研究所 | 一种异羟肟酸类衍生物及其制备方法和应用 |
| US12441707B2 (en) | 2019-12-30 | 2025-10-14 | Tyra Biosciences, Inc. | Indazole compounds |
| WO2021195260A1 (en) | 2020-03-25 | 2021-09-30 | Forge Therapeutics, Inc. | Lpxc inhibitor and methods of making |
| JP7620649B2 (ja) | 2020-06-10 | 2025-01-23 | アリゴス セラピューティクス インコーポレイテッド | コロナウイルス、ピコルナウイルス及びノロウイルス感染を治療するための抗ウイルス化合物 |
| CR20230576A (es) | 2021-06-14 | 2024-04-05 | Scorpion Therapeutics Inc | Derivados de la urea que pueden ser utilizados para tratar el cáncer |
| AU2022306289A1 (en) | 2021-07-09 | 2024-01-18 | Aligos Therapeutics, Inc. | Anti-viral compounds |
| WO2023011573A1 (zh) * | 2021-08-05 | 2023-02-09 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和用途 |
| WO2023043816A1 (en) | 2021-09-17 | 2023-03-23 | Aligos Therapeutics, Inc. | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
| MX2024003859A (es) | 2021-09-28 | 2024-05-21 | Blacksmith Medicines Inc | Inhibidores de lpxc y usos de estos. |
| JP2024545294A (ja) * | 2021-12-24 | 2024-12-05 | インターベット インターナショナル ベー． フェー． | ヒドロキシルアミン誘導体の調製方法 |
| WO2024067813A1 (zh) * | 2022-09-28 | 2024-04-04 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和其医药上的用途 |
| CN115480037B (zh) * | 2022-10-14 | 2023-07-18 | 青岛国泰检测科技有限公司 | 一种污水检测方法 |
| CN115598253B (zh) * | 2022-10-25 | 2025-02-21 | 无锡紫杉药业股份有限公司 | 一种多西他赛原料药中dcc和dcu残留的检测方法 |
| IL321433A (en) | 2022-12-16 | 2025-08-01 | Astrazeneca Ab | Purines 2,6,9 trimethylated |
| CN117586278A (zh) * | 2023-11-27 | 2024-02-23 | 华北制药集团先泰药业有限公司 | 一种氨苄西林钠杂质及其制备方法 |
| WO2025155681A1 (en) * | 2024-01-19 | 2025-07-24 | Corteva Agriscience Llc | Nitrification inhibiting mixtures |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US85369A (en) * | 1868-12-29 | Improved railway-car brake | ||
| US3167476A (en) * | 1965-01-26 | preparations acting on the central nervous | ||
| US2772281A (en) * | 1954-12-23 | 1956-11-27 | Merck & Co Inc | Synthesis of 4-amino-3-isoxazolidone and its derivatives |
| DE2441261A1 (de) * | 1974-08-28 | 1976-03-18 | Merck Patent Gmbh | Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung |
| US4077998A (en) * | 1975-10-28 | 1978-03-07 | Morton-Norwich Products, Inc. | Phthaloyl amino acid hydroxamic acids |
| US4613616A (en) * | 1984-07-20 | 1986-09-23 | Research Corporation | Polymeric iron chelators |
| JPS6187693A (ja) * | 1984-10-05 | 1986-05-06 | Fuji Yakuhin Kogyo Kk | ペプチジルヒドロキサム酸誘導体およびそれを含有するウレア−ゼ活性阻害剤 |
| US5214204A (en) * | 1991-07-19 | 1993-05-25 | Abbott Laboratories | Arylamidoalkyl-n-hydroxyurea compounds having lipoxygenase inhibitory activity |
| GB9503749D0 (en) | 1995-02-24 | 1995-04-12 | British Biotech Pharm | Synthesis of hydroxamic acid derivatives |
| KR100332273B1 (ko) | 1995-07-26 | 2002-06-20 | 디. 제이. 우드, 스피겔 알렌 제이 | 엔-(아로일)글리신하이드록삼산유도체및이와관련된화합물 |
| US5925659A (en) * | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| WO1998015525A1 (en) | 1996-10-07 | 1998-04-16 | Sumitomo Pharmaceuticals Co., Ltd. | Hydroxamic acids |
| AU5426398A (en) | 1996-10-28 | 1998-05-22 | Versicor Inc | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof |
| US6281245B1 (en) | 1996-10-28 | 2001-08-28 | Versicor, Inc. | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof |
| AR016751A1 (es) | 1996-11-22 | 2001-08-01 | Athena Neurosciences Inc | Metodo para inhibir la liberacion del peptido beta-amiloide en una celula, composicion farmaceutica y compuestos utiles en dicho metodo |
| GB9715030D0 (en) * | 1997-07-18 | 1997-09-24 | British Biotech Pharm | Metalloproteinase inhibitors |
| WO1999006340A2 (en) * | 1997-07-31 | 1999-02-11 | The Procter & Gamble Company | Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors |
| EP1024134A4 (en) | 1997-10-09 | 2003-05-14 | Ono Pharmaceutical Co | DERIVATIVES OF AMINOBUTANIC ACID |
| EP1052984B1 (en) | 1998-02-07 | 2004-05-12 | Vernalis (Oxford) Ltd | Antibacterial agents |
| US5952537A (en) | 1998-03-13 | 1999-09-14 | Wiley Organics, Inc. | Preparation of cycloalkylacetylene compounds using dialkylaminomagnesium halide or bis(dialkylamino)magnesium |
| WO2000002904A1 (en) | 1998-07-08 | 2000-01-20 | Harald Tschesche | Matrix metalloproteinase inhibitors containing aminomalonic acid derivatives and peptide backbone modified derivatives thereof |
| GB9901863D0 (en) | 1999-01-29 | 1999-03-17 | British Biotech Pharm | Antibacterial agents |
| CA2366264A1 (en) | 1999-04-02 | 2000-10-12 | Bristol-Myers Squibb Company | Novel amide derivatives as inhibitors of matrix metalloproteinases, tnf-.alpha., and aggrecanase |
| EP1169031A1 (en) | 1999-04-09 | 2002-01-09 | British Biotech Pharmaceuticals Limited | Antimicrobial agents |
| US6699899B1 (en) * | 1999-12-21 | 2004-03-02 | Celgene Corporation | Substituted acylhydroxamic acids and method of reducing TNFα levels |
| JP2003528097A (ja) * | 2000-03-17 | 2003-09-24 | ブリストル−マイヤーズ スクイブ ファーマ カンパニー | マトリックスメタロプロテアーゼおよびＴＮＦ−α阻害剤としてのβ−アミノ酸誘導体 |
| CA2404002A1 (en) * | 2000-03-24 | 2001-09-27 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| EP2083005A1 (en) | 2000-09-29 | 2009-07-29 | TopoTarget UK Limited | Carbamic acid compounds comprising an amide linkage as HDAC inhibitors |
| WO2002030873A1 (en) | 2000-10-10 | 2002-04-18 | Fujisawa Pharmaceutical Co., Ltd. | Mmp inhibitor |
| WO2002050081A2 (en) | 2000-12-21 | 2002-06-27 | De Novo Pharmaceuticals Ltd | Antimicrobial agents |
| AR035417A1 (es) * | 2001-01-27 | 2004-05-26 | Hoffmann La Roche | Derivados triciclicos de lactama y sultama, procesos para su elaboracion, medicamentos que los contienen, y el uso de dichos compuestos en la preparacion de medicamentos |
| JPWO2002074298A1 (ja) * | 2001-03-21 | 2004-07-08 | 小野薬品工業株式会社 | Ｉｌ−６産生阻害剤 |
| US6436933B1 (en) * | 2001-03-26 | 2002-08-20 | Structural Bioinformatics Inc. | Inhibitors of anthrax lethal factor activity |
| US6852882B2 (en) * | 2001-06-05 | 2005-02-08 | Smithkline Beecham Corporation | Peptide deformylase inhibitors |
| JP2004536113A (ja) | 2001-07-03 | 2004-12-02 | カイロン コーポレイション | チロシンキナーゼおよびセリン／スレオニンキナーゼのインヒビターとしてのインダゾールベンズイミダゾール化合物 |
| HRP20040415A2 (en) * | 2001-11-13 | 2005-04-30 | 3-Dimensional Pharmaceuticals | Substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer |
| PT1511472E (pt) * | 2002-05-29 | 2009-07-24 | Merck & Co Inc | Compostos úteis no tratamento de antrax e inibição do factor letal |
| KR101011373B1 (ko) * | 2002-07-11 | 2011-01-28 | 비큐론 파마슈티컬스 인코포레이티드 | 항균작용을 갖는 ｎ-히드록시아미드 유도체 |
| US7282608B2 (en) | 2002-10-17 | 2007-10-16 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| JP2004143053A (ja) * | 2002-10-22 | 2004-05-20 | Senju Pharmaceut Co Ltd | β−アミノヒドロキサム酸誘導体およびその用途 |
| US7173058B2 (en) * | 2002-12-30 | 2007-02-06 | Celgene Corporation | Fluoroalkoxy-substituted 1,3-dihydro-isoindolyl compounds and their pharmaceutical uses |
| AU2004204760C1 (en) * | 2003-01-08 | 2010-08-19 | Novartis Vaccines And Diagnostics, Inc. | Antibacterial agents |
| US20040155210A1 (en) * | 2003-02-07 | 2004-08-12 | Wears William E. | Instrument mounting apparatus for a fluid control valve |
| NZ542671A (en) * | 2003-03-12 | 2008-12-24 | Celgene Corp | 7-Amido-isoindolyl compounds and their pharmaceutical uses |
| WO2004110989A1 (en) * | 2003-05-14 | 2004-12-23 | Bayer Pharmaceuticals Corporation | N-hydroxy-7-(arylamino)heptanamide derivatives useful for treating hyper-proliferative disorders |
| JP5065910B2 (ja) * | 2005-01-14 | 2012-11-07 | グラクソ グループ リミテッド | ビオチンおよび光親和性基を含む、マクロライド標的同定用のマクロライド化合物 |
| GT200600196A (es) * | 2005-05-23 | 2007-01-15 | Compuestos n-formil de hidroxilamina | |
| WO2006131303A2 (en) * | 2005-06-07 | 2006-12-14 | Novartis Ag | Peptide deformylase (pdf) inhibitors 4 |
| US20070066646A1 (en) * | 2005-08-02 | 2007-03-22 | Genmedica Therapeutics Sl | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof |
| AU2006320604A1 (en) | 2005-12-01 | 2007-06-07 | Schering Corporation | Compounds for the treatment of inflammatory disorders and microbial diseases |
| US8088804B2 (en) | 2005-12-15 | 2012-01-03 | Pfizer Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| CN101528711A (zh) | 2006-08-31 | 2009-09-09 | 先灵公司 | 可用作抗细菌剂的乙内酰脲衍生物 |
| CN101209974A (zh) | 2006-12-31 | 2008-07-02 | 天津药物研究院 | 异羟肟酸类衍生物及其用途 |
| WO2008105515A1 (ja) | 2007-02-28 | 2008-09-04 | Taisho Pharmaceutical Co., Ltd. | 新規なヒドロキサム酸誘導体 |
| EP2170814B1 (en) | 2007-06-12 | 2016-08-17 | Achaogen, Inc. | Antibacterial agents |
| ES2408932T3 (es) | 2008-06-25 | 2013-06-24 | Merck Sharp & Dohme Corp. | Síntesis y uso de agentes antibacterianos heterocíclicos |
| AU2009279949A1 (en) | 2008-08-04 | 2010-02-11 | Merck Sharp & Dohme Corp. | Urea derivatives as antibacterial agents |
| WO2010024356A1 (ja) | 2008-08-27 | 2010-03-04 | 大正製薬株式会社 | ナフチリジン－ｎ－オキシドを有する新規ヒドロキサム酸誘導体 |
| US8372885B2 (en) * | 2008-09-17 | 2013-02-12 | Novartis Ag | Organic compounds and their uses |
| US8722686B2 (en) | 2008-09-19 | 2014-05-13 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| WO2010100475A1 (en) | 2009-03-02 | 2010-09-10 | Astrazeneca Ab | Hydroxamic acid derivatives as gram-negative antibacterial agents |
| WO2011005355A1 (en) * | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| EP2488489A2 (en) | 2009-10-13 | 2012-08-22 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| CA2899583A1 (en) | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| TWI543961B (zh) | 2010-04-20 | 2016-08-01 | 大正製藥股份有限公司 | Novel hydroxamic acid derivatives |
| BR112013011693A2 (pt) | 2010-11-10 | 2016-08-09 | Achaogen Inc | derivados de ácido hidroxâmico e seu uso no tratamento de infecções por bactérias |
| TW201315710A (zh) | 2011-09-12 | 2013-04-16 | Achaogen Inc | Ｎ－（（ｓ）－３－胺基－１－（羥胺基）－３－甲基－１－酮基丁－２－基）－４－（（（１ｒ，２ｒ）－２－（羥甲基）環丙基）丁－１，３－二炔基）苯甲醯胺之多晶型 |
| WO2013170030A1 (en) | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
-
2008
- 2008-06-12 EP EP08770882.2A patent/EP2170814B1/en not_active Not-in-force
- 2008-06-12 TW TW105140893A patent/TW201716375A/zh unknown
- 2008-06-12 CA CA2691987A patent/CA2691987C/en not_active Expired - Fee Related
- 2008-06-12 WO PCT/US2008/066766 patent/WO2008154642A2/en not_active Ceased
- 2008-06-12 ES ES08770882.2T patent/ES2602615T3/es active Active
- 2008-06-12 EP EP12008040.3A patent/EP2662353A3/en not_active Withdrawn
- 2008-06-12 TW TW104136910A patent/TWI574941B/zh not_active IP Right Cessation
- 2008-06-12 CA CA2934114A patent/CA2934114A1/en not_active Abandoned
- 2008-06-12 CN CN201710094691.XA patent/CN107021895A/zh active Pending
- 2008-06-12 TW TW097121956A patent/TWI426068B/zh not_active IP Right Cessation
- 2008-06-12 CN CN200880100181.8A patent/CN101765585B/zh not_active Expired - Fee Related
- 2008-06-12 JP JP2010512358A patent/JP5539864B2/ja not_active Expired - Fee Related
- 2008-06-12 TW TW103100835A patent/TWI519508B/zh not_active IP Right Cessation
-
2009
- 2009-12-10 US US12/635,551 patent/US20100190766A1/en not_active Abandoned
-
2014
- 2014-03-24 US US14/223,971 patent/US9617256B2/en not_active Expired - Fee Related
- 2014-05-01 JP JP2014094451A patent/JP2014177468A/ja active Pending
-
2016
- 2016-11-29 JP JP2016231270A patent/JP2017081931A/ja active Pending
- 2016-12-12 US US15/376,073 patent/US20170088549A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010530372A5 (enExample) | ||
| JP2009526034A5 (enExample) | ||
| JP2005539088A5 (enExample) | ||
| JP2006182786A5 (enExample) | ||
| JP2005523922A5 (enExample) | ||
| JP2010530881A5 (enExample) | ||
| JP2019094345A5 (enExample) | ||
| JP2019532928A5 (enExample) | ||
| JP2004516314A5 (enExample) | ||
| JP2009535307A5 (enExample) | ||
| JP2009500423A5 (enExample) | ||
| JP2004534846A5 (enExample) | ||
| JP2004502752A5 (enExample) | ||
| WO2007091106A3 (en) | Treatment of duchenne muscular dystrophy | |
| JP2005500311A5 (enExample) | ||
| CN111836814A (zh) | 稠环化合物、其制备方法及用途 | |
| CY1111980T1 (el) | Παραγωγα του αμιδιου τα οποια φερουν ενα υποκαταστατο του κυκλοπροπυλαμινοκαρβονυλιου και χρησιμευουν ως αναστολεις κυτταροκινης | |
| JP2003306481A5 (enExample) | ||
| JP2007517037A5 (enExample) | ||
| JPWO2023099592A5 (enExample) | ||
| JP2002525323A5 (enExample) | ||
| JP2001525394A5 (enExample) | ||
| JP2004502755A5 (enExample) | ||
| NO20055655D0 (no) | Anvendelse av azetidinkarboksamidderivater i terapi | |
| JP2006515866A5 (enExample) |