JP2010530372A5 - - Google Patents
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- JP2010530372A5 JP2010530372A5 JP2010512358A JP2010512358A JP2010530372A5 JP 2010530372 A5 JP2010530372 A5 JP 2010530372A5 JP 2010512358 A JP2010512358 A JP 2010512358A JP 2010512358 A JP2010512358 A JP 2010512358A JP 2010530372 A5 JP2010530372 A5 JP 2010530372A5
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- substituted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94349407P | 2007-06-12 | 2007-06-12 | |
| US60/943,494 | 2007-06-12 | ||
| PCT/US2008/066766 WO2008154642A2 (en) | 2007-06-12 | 2008-06-12 | Antibacterial agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014094451A Division JP2014177468A (ja) | 2007-06-12 | 2014-05-01 | 抗菌剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010530372A JP2010530372A (ja) | 2010-09-09 |
| JP2010530372A5 true JP2010530372A5 (enExample) | 2011-07-14 |
| JP5539864B2 JP5539864B2 (ja) | 2014-07-02 |
Family
ID=39816683
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010512358A Expired - Fee Related JP5539864B2 (ja) | 2007-06-12 | 2008-06-12 | 抗菌剤 |
| JP2014094451A Pending JP2014177468A (ja) | 2007-06-12 | 2014-05-01 | 抗菌剤 |
| JP2016231270A Pending JP2017081931A (ja) | 2007-06-12 | 2016-11-29 | 抗菌剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014094451A Pending JP2014177468A (ja) | 2007-06-12 | 2014-05-01 | 抗菌剤 |
| JP2016231270A Pending JP2017081931A (ja) | 2007-06-12 | 2016-11-29 | 抗菌剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20100190766A1 (enExample) |
| EP (2) | EP2662353A3 (enExample) |
| JP (3) | JP5539864B2 (enExample) |
| CN (2) | CN107021895A (enExample) |
| CA (2) | CA2691987C (enExample) |
| ES (1) | ES2602615T3 (enExample) |
| TW (4) | TWI574941B (enExample) |
| WO (1) | WO2008154642A2 (enExample) |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2121687T3 (pl) | 2006-12-22 | 2016-03-31 | Astex Therapeutics Ltd | Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowej |
| EP2114941B1 (en) | 2006-12-22 | 2015-03-25 | Astex Therapeutics Limited | Bicyclic heterocyclic compounds as fgfr inhibitors |
| TWI574941B (zh) * | 2007-06-12 | 2017-03-21 | Achaogen Inc | 抗菌劑 |
| GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
| GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
| US20110092554A1 (en) * | 2007-11-19 | 2011-04-21 | Richard Chesworth | 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders |
| US8217064B2 (en) | 2007-12-20 | 2012-07-10 | Envivo Pharmaceuticals, Inc. | Tetrasubstituted benzenes |
| US8242145B2 (en) | 2008-02-14 | 2012-08-14 | Panmira Pharmaceuticals, Llc | Cyclic diaryl ether compounds as antagonists of prostaglandin D2 receptors |
| EP2268611A2 (en) | 2008-04-02 | 2011-01-05 | Amira Pharmaceuticals, Inc. | Aminoalkylphenyl antagonists of prostaglandin d2 receptors |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| EP2307365B1 (en) * | 2008-06-25 | 2013-03-27 | Merck Sharp & Dohme Corp. | Synthesis and use of heterocyclic antibacterial agents |
| BRPI0913930A2 (pt) | 2008-07-03 | 2015-10-20 | Amira Pharmaceuticals Inc | antagonistas de receptores de prostaglandinas d2 |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| US8372885B2 (en) * | 2008-09-17 | 2013-02-12 | Novartis Ag | Organic compounds and their uses |
| US8383654B2 (en) | 2008-11-17 | 2013-02-26 | Panmira Pharmaceuticals, Llc | Heterocyclic antagonists of prostaglandin D2 receptors |
| GB0906472D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| GB0906470D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| WO2011005355A1 (en) * | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| FR2950056B1 (fr) | 2009-09-17 | 2011-08-26 | Galderma Res & Dev | Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique |
| FR2950057B1 (fr) | 2009-09-17 | 2011-08-26 | Galderma Res & Dev | Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique |
| EA023350B1 (ru) | 2009-10-16 | 2016-05-31 | Мелинта Терапьютикс, Инк. | Противомикробные соединения, способы их получения и применение |
| DK2488525T3 (en) | 2009-10-16 | 2018-08-06 | Melinta Therapeutics Inc | ANTIMICROBIAL COMPOUNDS AND PROCEDURES FOR PREPARING AND USING THEREOF |
| EP3421476A1 (en) | 2009-10-16 | 2019-01-02 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| JP2013516475A (ja) | 2010-01-06 | 2013-05-13 | アミラ ファーマシューティカルズ，インク． | Ｄｐ２アンタゴニストおよびその使用 |
| AU2011243597B2 (en) | 2010-04-20 | 2014-05-08 | Taisho Pharmaceutical Co., Ltd. | Novel hydroxamic acid derivative |
| US8835472B2 (en) * | 2010-09-02 | 2014-09-16 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| US9738604B2 (en) | 2010-09-03 | 2017-08-22 | Duke University | Ethynylbenzene derivatives |
| KR20140023869A (ko) | 2010-11-10 | 2014-02-27 | 아카오젠, 인코포레이티드 | 하이드록삼산 유도체 및 세균 감염 치료에서의 이들의 사용 |
| SG194489A1 (en) | 2011-04-15 | 2013-12-30 | Melinta Therapeutics Inc | Antimicrobial compounds and methods of making and using the same |
| UY34305A (es) | 2011-09-01 | 2013-04-30 | Novartis Ag | Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar |
| AR087843A1 (es) | 2011-09-12 | 2014-04-23 | Achaogen Inc | Formas polimorficas de n-((s)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1r,2r)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida |
| CN102603690A (zh) * | 2012-01-17 | 2012-07-25 | 凯莱英医药集团（天津）股份有限公司 | 一种一锅法制备四氢吡喃-4-甲酸及其衍生物的方法 |
| CA2864672C (en) | 2012-02-17 | 2018-01-09 | Millennium Pharmaceuticals, Inc. | Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme |
| WO2013170030A1 (en) * | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| US9196844B2 (en) * | 2012-06-01 | 2015-11-24 | Semiconductor Energy Laboratory Co., Ltd. | Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device |
| US9073921B2 (en) | 2013-03-01 | 2015-07-07 | Novartis Ag | Salt forms of bicyclic heterocyclic derivatives |
| WO2014165075A1 (en) | 2013-03-12 | 2014-10-09 | Achaogen, Inc. | Antibacterial agents |
| RS58930B1 (sr) | 2013-03-15 | 2019-08-30 | Fujifilm Toyama Chemical Co Ltd | Novi derivati hidroksaminske kiseline ili njihova so |
| GB201307233D0 (en) * | 2013-04-22 | 2013-05-29 | Vib Vzw | Compounds and uses thereof |
| JP6378759B2 (ja) | 2013-07-02 | 2018-08-22 | ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Ｓｕｍｏ活性化酵素阻害剤として有用なヘテロアリール化合物 |
| JP6458270B2 (ja) | 2013-08-16 | 2019-01-30 | デューク ユニバーシティ | 置換されたヒドロキサム酸化合物 |
| US10189786B2 (en) | 2013-08-16 | 2019-01-29 | Duke University | Antibacterial compounds |
| WO2015024016A2 (en) | 2013-08-16 | 2015-02-19 | Duke University | 2-piperidinyl substituted n,3-dihydroxybutanamides |
| EP3038623A4 (en) | 2013-09-09 | 2017-04-19 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| CA2923214A1 (en) | 2013-09-09 | 2015-03-12 | Melinta Therapeutics, Inc. | Antimicrobial compounds and methods of making and using the same |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| JP2016210682A (ja) * | 2013-10-18 | 2016-12-15 | 大正製薬株式会社 | ヒドロキサム酸誘導体 |
| WO2015056799A1 (ja) * | 2013-10-18 | 2015-04-23 | 大正製薬株式会社 | ヒドロキサム酸誘導体 |
| JP2016210683A (ja) * | 2013-10-18 | 2016-12-15 | 大正製薬株式会社 | ヒドロキサム酸誘導体 |
| EA030730B1 (ru) | 2013-12-19 | 2018-09-28 | Идорсиа Фармасьютиклз Лтд | Антибактериальные производные 1h-индазола и 1h-индола |
| US9539305B1 (en) | 2014-03-14 | 2017-01-10 | Fleurir Abx Llc | Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof |
| WO2015173329A1 (en) * | 2014-05-16 | 2015-11-19 | Actelion Pharmaceuticals Ltd | Antibacterial quinazoline-4(3h)-one derivatives |
| KR102567244B1 (ko) * | 2014-06-12 | 2023-08-16 | 세다르스-신나이 메디칼 센터 | 암을 치료하는 조성물 및 방법 |
| JP6603712B2 (ja) | 2014-07-01 | 2019-11-06 | ミレニアム ファーマシューティカルズ， インコーポレイテッド | Ｓｕｍｏ活性化酵素の阻害薬として有用なヘテロアリール化合物 |
| WO2016039432A1 (ja) | 2014-09-12 | 2016-03-17 | 富山化学工業株式会社 | 新規なヒドロキサム酸誘導体および抗菌性物質を組み合わせて使用する方法 |
| SG11201701956TA (en) | 2014-09-12 | 2017-04-27 | Toyama Chemical Co Ltd | Novel pharmaceutical composition containing hydroxamic acid derivative or salt thereof |
| CN104231024B (zh) * | 2014-10-11 | 2016-06-15 | 吉首大学 | 噁二唑-肌苷型化合物作为TyrRS抑制剂及其制法和用途 |
| CN104327140B (zh) * | 2014-10-11 | 2016-06-15 | 吉首大学 | 噁唑烷酮-腺苷型多靶点抗菌化合物及其制法和用途 |
| CN104262433B (zh) * | 2014-10-11 | 2016-06-15 | 吉首大学 | 噁二唑-腺苷型化合物作为TyrRS抑制剂及其制法和用途 |
| CN104341476A (zh) * | 2014-10-11 | 2015-02-11 | 吉首大学 | 利奈唑胺-肌苷型多靶点抗菌化合物及其制法和用途 |
| CN104341475A (zh) * | 2014-10-11 | 2015-02-11 | 吉首大学 | 利奈唑胺-腺苷型多靶点抗菌化合物及其制法和用途 |
| CN105777464B (zh) * | 2014-12-26 | 2020-09-29 | 中国科学院上海药物研究所 | 异羟肟酸衍生物及其制备方法和应用 |
| JP6208161B2 (ja) * | 2015-02-06 | 2017-10-04 | 信越化学工業株式会社 | 非対称共役ジイン化合物の製造方法及びこれを用いたｚ，ｚ−共役ジエン化合物の製造方法 |
| MX2017011616A (es) | 2015-03-11 | 2018-04-11 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos para hacerlos y usarlos. |
| EP3374355A4 (en) | 2015-11-09 | 2019-04-17 | Forge Therapeutics, Inc. | COMPOUNDS BASED ON PYRONE AND METHOD FOR THE TREATMENT OF BACTERIAL INFECTIONS |
| US10414735B2 (en) | 2015-11-09 | 2019-09-17 | Forge Therapeutics, Inc. | Substituted hydroxypyrimidinones for treating bacterial infections |
| US10781184B2 (en) * | 2015-12-08 | 2020-09-22 | Glaxosmithkline Intellectual Property Development Limited | Substituted benzazinones as antibacterial compounds |
| CN105669750B (zh) * | 2016-03-01 | 2018-04-03 | 中国医学科学院医药生物技术研究所 | 新型锌离子螯合剂及其制备和在抗革兰氏阴性菌感染中的应用 |
| KR102408800B1 (ko) * | 2016-03-07 | 2022-06-13 | 머크 샤프 앤드 돔 코포레이션 | 비시클릭 아릴 모노박탐 화합물 및 박테리아 감염의 치료를 위한 그의 사용 방법 |
| WO2017156071A1 (en) | 2016-03-09 | 2017-09-14 | Blade Therapeutics, Inc. | Cyclic keto-amide compounds as calpain modulators and methods of production and use thereof |
| DK3445744T3 (da) * | 2016-04-18 | 2021-12-13 | Vivoryon Therapeutics N V | Hidtil ukendte inhibitorer af meprin-alfa og -beta. |
| EP3448375B1 (en) | 2016-04-25 | 2023-09-27 | Duke University | Benzoylglycine derivatives and methods of making and using same |
| CN110312722A (zh) | 2016-05-06 | 2019-10-08 | 生物验证系统股份公司 | 抗微生物剂及其制备和使用方法 |
| AR108864A1 (es) | 2016-06-23 | 2018-10-03 | Achaogen Inc | Agentes antibacterianos |
| US11292801B2 (en) | 2016-07-05 | 2022-04-05 | Blade Therapeutics, Inc. | Calpain modulators and therapeutic uses thereof |
| BR112019006110A2 (pt) | 2016-09-28 | 2019-09-10 | Blade Therapeutics Inc | moduladores de calpaína e usos terapêuticos dos mesmos |
| CN110072844B (zh) * | 2016-12-23 | 2023-06-02 | 英特维特国际股份有限公司 | 用于治疗溶血曼海姆菌或睡眠嗜组织菌感染的化合物 |
| EP4570317A3 (en) * | 2016-12-23 | 2025-09-17 | Intervet International B.V. | Compounds for the treatment of bovine or swine respiratory disease |
| EP3615529B1 (en) | 2017-04-26 | 2024-06-05 | Basilea Pharmaceutica International AG, Allschwil | Processes for the preparation of furazanobenzimidazoles and crystalline forms thereof |
| EP3621961A4 (en) * | 2017-05-10 | 2020-09-09 | Forge Therapeutics, Inc. | Antibacterial compounds |
| EP3621962A4 (en) | 2017-05-10 | 2020-12-09 | Forge Therapeutics, Inc. | ANTIBACTERIAL COMPOUNDS |
| BR112020001619A2 (pt) * | 2017-07-27 | 2020-07-21 | BioMendics, LLC | tolanos substituídos para a modulação da colonização microbiana |
| EP3672946B1 (en) * | 2017-08-21 | 2024-12-04 | Microbiotix, Inc. | Metabolically stable n-acylaminooxadiazoles useful as antibacterial agents |
| BR112020016270A2 (pt) * | 2018-02-10 | 2020-12-15 | Kbp Biosciences Co., Ltd. | Composto atuando como antibióticos |
| US10730874B2 (en) | 2018-03-13 | 2020-08-04 | Shire Human Genetic Therapies, Inc. | Inhibitors of plasma kallikrein and uses thereof |
| WO2020061103A1 (en) | 2018-09-18 | 2020-03-26 | Nikang Therapeutics, Inc. | Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors |
| BR112021005044A2 (pt) | 2018-09-20 | 2021-06-08 | Forge Therapeutics, Inc. | compostos antibacterianos |
| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| HUE070112T2 (hu) | 2018-10-30 | 2025-05-28 | Gilead Sciences Inc | 3-(Kinolin-8-il)-1,4-dihidropirido[3,4-d]pirimidin-2,4-dion-származékok mint alpha4beta7 integrin gátlók gyulladásos betegségek kezelésére |
| KR102652797B1 (ko) | 2018-10-30 | 2024-04-02 | 길리애드 사이언시즈, 인코포레이티드 | 알파4베타7 인테그린의 억제를 위한 화합물 |
| CA3115830C (en) | 2018-10-30 | 2023-09-12 | Gilead Sciences, Inc. | Compounds for inhibition of .alpha.4.beta.7 integrin |
| WO2020102572A1 (en) * | 2018-11-14 | 2020-05-22 | Forge Therapeutics, Inc. | Antibacterial compounds |
| CN112996505A (zh) * | 2018-11-21 | 2021-06-18 | 大正制药株式会社 | 新型咪唑衍生物 |
| WO2021030438A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| WO2021055621A1 (en) | 2019-09-18 | 2021-03-25 | Shire Human Genetic Therapies, Inc. | Plasma kallikrein inhibitors and uses thereof |
| JP7695232B2 (ja) | 2019-09-18 | 2025-06-18 | 武田薬品工業株式会社 | ヘテロアリール血漿カリクレインインヒビター |
| CN110563611B (zh) * | 2019-09-19 | 2021-02-02 | 中国医学科学院医药生物技术研究所 | 一种异羟肟酸类衍生物及其制备方法和应用 |
| WO2021138391A1 (en) | 2019-12-30 | 2021-07-08 | Tyra Biosciences, Inc. | Indazole compounds |
| WO2021195260A1 (en) | 2020-03-25 | 2021-09-30 | Forge Therapeutics, Inc. | Lpxc inhibitor and methods of making |
| CN116096714A (zh) | 2020-06-10 | 2023-05-09 | 安力高医药股份有限公司 | 用于治疗冠状病毒、小核糖核酸病毒和诺罗病毒感染的抗病毒化合物 |
| WO2022265993A1 (en) | 2021-06-14 | 2022-12-22 | Scorpion Therapeutics, Inc. | Urea derivatives which can be used to treat cancer |
| PE20240775A1 (es) | 2021-07-09 | 2024-04-17 | Aligos Therapeutics Inc | Compuestos antivirales |
| CN117751113A (zh) * | 2021-08-05 | 2024-03-22 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和用途 |
| WO2023043816A1 (en) | 2021-09-17 | 2023-03-23 | Aligos Therapeutics, Inc. | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
| CN118302429A (zh) | 2021-09-28 | 2024-07-05 | 布莱克史密斯医药公司 | Lpxc抑制剂及其用途 |
| EP4452921A1 (en) * | 2021-12-24 | 2024-10-30 | Intervet International B.V. | Process of the preparation of hydroxylamine derivatives |
| WO2024067813A1 (zh) * | 2022-09-28 | 2024-04-04 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和其医药上的用途 |
| CN115480037B (zh) * | 2022-10-14 | 2023-07-18 | 青岛国泰检测科技有限公司 | 一种污水检测方法 |
| CN115598253B (zh) * | 2022-10-25 | 2025-02-21 | 无锡紫杉药业股份有限公司 | 一种多西他赛原料药中dcc和dcu残留的检测方法 |
| KR20250121114A (ko) | 2022-12-16 | 2025-08-11 | 아스트라제네카 아베 | 2,6,9-삼치환된 퓨린 |
| CN117586278A (zh) * | 2023-11-27 | 2024-02-23 | 华北制药集团先泰药业有限公司 | 一种氨苄西林钠杂质及其制备方法 |
| WO2025155681A1 (en) * | 2024-01-19 | 2025-07-24 | Corteva Agriscience Llc | Nitrification inhibiting mixtures |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3167476A (en) * | 1965-01-26 | preparations acting on the central nervous | ||
| US85369A (en) * | 1868-12-29 | Improved railway-car brake | ||
| US2772281A (en) * | 1954-12-23 | 1956-11-27 | Merck & Co Inc | Synthesis of 4-amino-3-isoxazolidone and its derivatives |
| DE2441261A1 (de) * | 1974-08-28 | 1976-03-18 | Merck Patent Gmbh | Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung |
| US4077998A (en) * | 1975-10-28 | 1978-03-07 | Morton-Norwich Products, Inc. | Phthaloyl amino acid hydroxamic acids |
| US4613616A (en) * | 1984-07-20 | 1986-09-23 | Research Corporation | Polymeric iron chelators |
| JPS6187693A (ja) * | 1984-10-05 | 1986-05-06 | Fuji Yakuhin Kogyo Kk | ペプチジルヒドロキサム酸誘導体およびそれを含有するウレア−ゼ活性阻害剤 |
| US5214204A (en) * | 1991-07-19 | 1993-05-25 | Abbott Laboratories | Arylamidoalkyl-n-hydroxyurea compounds having lipoxygenase inhibitory activity |
| GB9503749D0 (en) * | 1995-02-24 | 1995-04-12 | British Biotech Pharm | Synthesis of hydroxamic acid derivatives |
| PT850215E (pt) | 1995-07-26 | 2001-03-30 | Pfizer | Derivados de acidos n-(aroil)glicina-hidroxamicos e compostos relacionados |
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| WO1998015525A1 (en) | 1996-10-07 | 1998-04-16 | Sumitomo Pharmaceuticals Co., Ltd. | Hydroxamic acids |
| AU5426398A (en) | 1996-10-28 | 1998-05-22 | Versicor Inc | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof |
| US6281245B1 (en) | 1996-10-28 | 2001-08-28 | Versicor, Inc. | Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof |
| AR016751A1 (es) | 1996-11-22 | 2001-08-01 | Athena Neurosciences Inc | Metodo para inhibir la liberacion del peptido beta-amiloide en una celula, composicion farmaceutica y compuestos utiles en dicho metodo |
| GB9715030D0 (en) * | 1997-07-18 | 1997-09-24 | British Biotech Pharm | Metalloproteinase inhibitors |
| NZ503945A (en) * | 1997-07-31 | 2002-11-26 | Procter & Gamble | Metalloprotease-inhibiting amide derivatives |
| US6420427B1 (en) * | 1997-10-09 | 2002-07-16 | Ono Pharmaceutical Co., Ltd. | Aminobutyric acid derivatives |
| HUP0102901A3 (en) | 1998-02-07 | 2002-12-28 | British Biotech Pharm | Use of n-formyl hydroxylamines as antibacterial agents |
| US5952537A (en) | 1998-03-13 | 1999-09-14 | Wiley Organics, Inc. | Preparation of cycloalkylacetylene compounds using dialkylaminomagnesium halide or bis(dialkylamino)magnesium |
| WO2000002904A1 (en) | 1998-07-08 | 2000-01-20 | Harald Tschesche | Matrix metalloproteinase inhibitors containing aminomalonic acid derivatives and peptide backbone modified derivatives thereof |
| GB9901863D0 (en) | 1999-01-29 | 1999-03-17 | British Biotech Pharm | Antibacterial agents |
| CA2366264A1 (en) | 1999-04-02 | 2000-10-12 | Bristol-Myers Squibb Company | Novel amide derivatives as inhibitors of matrix metalloproteinases, tnf-.alpha., and aggrecanase |
| JP2002541197A (ja) | 1999-04-09 | 2002-12-03 | ブリティッシュ バイオテック ファーマシューティカルズ リミテッド | 抗菌剤 |
| US6699899B1 (en) * | 1999-12-21 | 2004-03-02 | Celgene Corporation | Substituted acylhydroxamic acids and method of reducing TNFα levels |
| EP1263756B1 (en) * | 2000-03-17 | 2004-02-25 | Bristol-Myers Squibb Pharma Company | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and tnf-alpha |
| US7288567B2 (en) * | 2000-03-24 | 2007-10-30 | Methylgene Inc. | Inhibitors of histone deacetylase |
| US7569724B2 (en) | 2000-09-29 | 2009-08-04 | Topotarget Uk Limited | Carbamic acid compounds comprising an amide linkage as HDAC inhibitors |
| WO2002030873A1 (en) | 2000-10-10 | 2002-04-18 | Fujisawa Pharmaceutical Co., Ltd. | Mmp inhibitor |
| US7323596B2 (en) * | 2000-12-21 | 2008-01-29 | De Novo Pharmaceuticals Ltd. | Antimicrobial agents |
| AR035417A1 (es) * | 2001-01-27 | 2004-05-26 | Hoffmann La Roche | Derivados triciclicos de lactama y sultama, procesos para su elaboracion, medicamentos que los contienen, y el uso de dichos compuestos en la preparacion de medicamentos |
| WO2002074298A1 (en) * | 2001-03-21 | 2002-09-26 | Ono Pharmaceutical Co., Ltd. | Il-6 production inhibitors |
| US6436933B1 (en) * | 2001-03-26 | 2002-08-20 | Structural Bioinformatics Inc. | Inhibitors of anthrax lethal factor activity |
| ES2374664T3 (es) * | 2001-06-05 | 2012-02-20 | Glaxosmithkline Llc | Inhibidores de péptido desformilasa. |
| US7064215B2 (en) | 2001-07-03 | 2006-06-20 | Chiron Corporation | Indazole benzimidazole compounds |
| IL161692A0 (en) * | 2001-11-13 | 2004-09-27 | Dimensional Pharm Inc | 14-benzodiazepine derivatives and pharmaceutical compositions containing the same |
| KR100701811B1 (ko) * | 2002-05-29 | 2007-04-02 | 머크 앤드 캄파니 인코포레이티드 | 탄저병의 치료 및 치사 인자의 억제에 유용한 화합물 |
| WO2004007444A2 (en) * | 2002-07-11 | 2004-01-22 | Vicuron Pharmaceuticals, Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| JP2006503082A (ja) | 2002-10-17 | 2006-01-26 | メシルジーン、インコーポレイテッド | ヒストンデアセチラーゼの阻害剤 |
| JP2004143053A (ja) * | 2002-10-22 | 2004-05-20 | Senju Pharmaceut Co Ltd | β−アミノヒドロキサム酸誘導体およびその用途 |
| ATE449081T1 (de) * | 2002-12-30 | 2009-12-15 | Celgene Corp | Fluoralkoxy-substituierte 1, 3-dihydro-isoindolyl-verbindungen und ihre pharmazeutischen verwendungen |
| ES2387803T3 (es) * | 2003-01-08 | 2012-10-02 | Novartis Vaccines And Diagnostics, Inc. | Agentes antibacterianos |
| US20040155210A1 (en) * | 2003-02-07 | 2004-08-12 | Wears William E. | Instrument mounting apparatus for a fluid control valve |
| CN1784382A (zh) * | 2003-03-12 | 2006-06-07 | 细胞基因公司 | 7－氨基－异吲哚基化合物及其药物用途 |
| WO2004110989A1 (en) * | 2003-05-14 | 2004-12-23 | Bayer Pharmaceuticals Corporation | N-hydroxy-7-(arylamino)heptanamide derivatives useful for treating hyper-proliferative disorders |
| WO2006106440A1 (en) * | 2005-01-14 | 2006-10-12 | Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. | Macrolide compounds containing biotin and photo-affinity group for macrolide target identification |
| GT200600196A (es) * | 2005-05-23 | 2007-01-15 | Compuestos n-formil de hidroxilamina | |
| AU2006256937C1 (en) * | 2005-06-07 | 2011-01-06 | Novartis Ag | Peptide deformylase (PDF) inhibitors 4 |
| US20070066646A1 (en) * | 2005-08-02 | 2007-03-22 | Genmedica Therapeutics Sl | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof |
| WO2007064732A1 (en) | 2005-12-01 | 2007-06-07 | Schering Corporation | Compounds for the treatment of inflammatory disorders and microbial diseases |
| EP2338878A3 (en) | 2005-12-15 | 2011-11-16 | Vicuron Pharmaceuticals, Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| CN101528711A (zh) | 2006-08-31 | 2009-09-09 | 先灵公司 | 可用作抗细菌剂的乙内酰脲衍生物 |
| CN101209974A (zh) | 2006-12-31 | 2008-07-02 | 天津药物研究院 | 异羟肟酸类衍生物及其用途 |
| JP5227304B2 (ja) | 2007-02-28 | 2013-07-03 | 大正製薬株式会社 | 新規なヒドロキサム酸誘導体 |
| TWI574941B (zh) | 2007-06-12 | 2017-03-21 | Achaogen Inc | 抗菌劑 |
| EP2307365B1 (en) | 2008-06-25 | 2013-03-27 | Merck Sharp & Dohme Corp. | Synthesis and use of heterocyclic antibacterial agents |
| EP2315746A1 (en) | 2008-08-04 | 2011-05-04 | Schering Corporation | Urea derivatives as antibacterial agents |
| WO2010024356A1 (ja) | 2008-08-27 | 2010-03-04 | 大正製薬株式会社 | ナフチリジン－ｎ－オキシドを有する新規ヒドロキサム酸誘導体 |
| US8372885B2 (en) | 2008-09-17 | 2013-02-12 | Novartis Ag | Organic compounds and their uses |
| WO2010032147A2 (en) | 2008-09-19 | 2010-03-25 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| WO2010100475A1 (en) | 2009-03-02 | 2010-09-10 | Astrazeneca Ab | Hydroxamic acid derivatives as gram-negative antibacterial agents |
| WO2011005355A1 (en) | 2009-05-07 | 2011-01-13 | Achaogen, Inc. | Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria |
| JP5671545B2 (ja) | 2009-10-13 | 2015-02-18 | ファイザー・インク | 抗菌薬として有用なｃ結合ヒドロキサム酸誘導体 |
| CA2782453C (en) | 2009-12-16 | 2015-11-24 | Matthew Frank Brown | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| AU2011243597B2 (en) | 2010-04-20 | 2014-05-08 | Taisho Pharmaceutical Co., Ltd. | Novel hydroxamic acid derivative |
| KR20140023869A (ko) | 2010-11-10 | 2014-02-27 | 아카오젠, 인코포레이티드 | 하이드록삼산 유도체 및 세균 감염 치료에서의 이들의 사용 |
| AR087843A1 (es) | 2011-09-12 | 2014-04-23 | Achaogen Inc | Formas polimorficas de n-((s)-3-amino-1-(hidroxiamino)-3-metil-1-oxobutan-2-il)-4-(((1r,2r)-2-(hidroximetil)ciclopropil)buta-1,3-dinil)benzamida |
| WO2013170030A1 (en) | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
-
2008
- 2008-06-12 TW TW104136910A patent/TWI574941B/zh not_active IP Right Cessation
- 2008-06-12 CN CN201710094691.XA patent/CN107021895A/zh active Pending
- 2008-06-12 TW TW105140893A patent/TW201716375A/zh unknown
- 2008-06-12 EP EP12008040.3A patent/EP2662353A3/en not_active Withdrawn
- 2008-06-12 ES ES08770882.2T patent/ES2602615T3/es active Active
- 2008-06-12 CA CA2691987A patent/CA2691987C/en not_active Expired - Fee Related
- 2008-06-12 JP JP2010512358A patent/JP5539864B2/ja not_active Expired - Fee Related
- 2008-06-12 TW TW103100835A patent/TWI519508B/zh not_active IP Right Cessation
- 2008-06-12 TW TW097121956A patent/TWI426068B/zh not_active IP Right Cessation
- 2008-06-12 CA CA2934114A patent/CA2934114A1/en not_active Abandoned
- 2008-06-12 CN CN200880100181.8A patent/CN101765585B/zh not_active Expired - Fee Related
- 2008-06-12 WO PCT/US2008/066766 patent/WO2008154642A2/en not_active Ceased
- 2008-06-12 EP EP08770882.2A patent/EP2170814B1/en not_active Not-in-force
-
2009
- 2009-12-10 US US12/635,551 patent/US20100190766A1/en not_active Abandoned
-
2014
- 2014-03-24 US US14/223,971 patent/US9617256B2/en not_active Expired - Fee Related
- 2014-05-01 JP JP2014094451A patent/JP2014177468A/ja active Pending
-
2016
- 2016-11-29 JP JP2016231270A patent/JP2017081931A/ja active Pending
- 2016-12-12 US US15/376,073 patent/US20170088549A1/en not_active Abandoned
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