JP2009526034A5 - - Google Patents
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- JP2009526034A5 JP2009526034A5 JP2008553834A JP2008553834A JP2009526034A5 JP 2009526034 A5 JP2009526034 A5 JP 2009526034A5 JP 2008553834 A JP2008553834 A JP 2008553834A JP 2008553834 A JP2008553834 A JP 2008553834A JP 2009526034 A5 JP2009526034 A5 JP 2009526034A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- aryl
- represent
- hydrogen
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003118 aryl group Chemical group 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 206010013801 Duchenne Muscular Dystrophy Diseases 0.000 claims 2
- 125000003435 aroyl group Chemical group 0.000 claims 2
- 125000001589 carboacyl group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004104 aryloxy group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000005415 substituted alkoxy group Chemical group 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0602768.4 | 2006-02-10 | ||
| GB0602768A GB0602768D0 (en) | 2006-02-10 | 2006-02-10 | Treatment of muscular dystrophy |
| GB0614690.6 | 2006-07-24 | ||
| GB0614690A GB0614690D0 (en) | 2006-07-24 | 2006-07-24 | Method of treatment of duchenne muscular dystrophy |
| GB0619281.9 | 2006-09-29 | ||
| GB0619281A GB0619281D0 (en) | 2006-09-29 | 2006-09-29 | Treatment of duchenne muscular dystrophy |
| GB0623983.4 | 2006-11-30 | ||
| GB0623983A GB0623983D0 (en) | 2006-11-30 | 2006-11-30 | Treatment of duchenne muscular dystrophy |
| PCT/GB2007/050055 WO2007091106A2 (en) | 2006-02-10 | 2007-02-09 | Treatment of duchenne muscular dystrophy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009526034A JP2009526034A (ja) | 2009-07-16 |
| JP2009526034A5 true JP2009526034A5 (enExample) | 2010-03-04 |
| JP5376956B2 JP5376956B2 (ja) | 2013-12-25 |
Family
ID=38229987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008553834A Expired - Fee Related JP5376956B2 (ja) | 2006-02-10 | 2007-02-09 | デュシェンヌ型筋ジストロフィーの治療 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8518980B2 (enExample) |
| EP (1) | EP1986633B1 (enExample) |
| JP (1) | JP5376956B2 (enExample) |
| KR (2) | KR101472248B1 (enExample) |
| AU (1) | AU2007213451B2 (enExample) |
| BR (1) | BRPI0707719A2 (enExample) |
| CA (1) | CA2641880C (enExample) |
| CY (1) | CY1115657T1 (enExample) |
| DK (1) | DK1986633T3 (enExample) |
| ES (1) | ES2522290T3 (enExample) |
| IL (2) | IL193315A (enExample) |
| MX (1) | MX2008010187A (enExample) |
| NZ (1) | NZ570625A (enExample) |
| PL (1) | PL1986633T3 (enExample) |
| PT (1) | PT1986633E (enExample) |
| SI (1) | SI1986633T1 (enExample) |
| WO (1) | WO2007091106A2 (enExample) |
Families Citing this family (69)
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| BRPI0712823A2 (pt) * | 2006-06-23 | 2012-07-24 | Abbott Lab | derivados de ciclopropil amina como moduladores de receptor de histamina h3 |
| US9108948B2 (en) | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
| AR063311A1 (es) * | 2006-10-18 | 2009-01-21 | Novartis Ag | Compuestos organicos |
| PL2170396T3 (pl) * | 2007-08-03 | 2017-07-31 | Summit (Oxford) Limited | Kombinacje leków do leczenia dystrofii mięśniowej Duchenne'a |
| GB0715937D0 (en) * | 2007-08-15 | 2007-09-26 | Vastox Plc | Method of treatment og duchenne muscular dystrophy |
| GB0715939D0 (en) * | 2007-08-15 | 2007-09-26 | Vastox Plc | Method of treatment of duchenne muscular dystrophy |
| GB0715938D0 (en) * | 2007-08-15 | 2007-09-26 | Vastox Plc | Method of treatment of duchenne muscular dystrophy |
| WO2009080788A2 (en) * | 2007-12-21 | 2009-07-02 | Universite Catholique De Louvain | Antibacterial agents |
| US20130023498A1 (en) * | 2008-02-20 | 2013-01-24 | The Wistar Institute and North Carolina State University | MicroRNA Modulators and Method for Identifying and Using the Same |
| JP5722030B2 (ja) * | 2008-03-31 | 2015-05-20 | 株式会社 資生堂 | しわを防止または改善するための経口、注射、皮膚外用剤および美容方法 |
| JP5369854B2 (ja) | 2008-04-21 | 2013-12-18 | 住友化学株式会社 | 有害節足動物防除組成物および縮合複素環化合物 |
| CN102026637B (zh) * | 2008-05-14 | 2012-12-12 | 株式会社大冢制药工场 | 包含苯衍生物的脂蛋白脂肪酶-活化组合物 |
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| GB0815369D0 (en) * | 2008-08-22 | 2008-10-01 | Summit Corp Plc | Compounds for treatment of duchenne muscular dystrophy |
| JP5764064B2 (ja) | 2008-09-26 | 2015-08-12 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗糖尿病薬として有用な新規な環状ベンゾイミダゾール誘導体 |
| MX2011004258A (es) | 2008-10-22 | 2011-06-01 | Merck Sharp & Dohme | Derivados de bencimidazol ciclicos novedosos utiles como agentes anti-diabeticos. |
| MX2011004505A (es) | 2008-10-29 | 2011-05-31 | Merck Sharp & Dohme | Derivados novedosos de bencimidazol ciclico, utiles como agentes antidiabeticos. |
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| GB0821307D0 (en) * | 2008-11-21 | 2008-12-31 | Summit Corp Plc | Compounds for treatment of duchenne muscular dystrophy |
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| US8969342B2 (en) * | 2009-03-20 | 2015-03-03 | Brandeis University | Compounds and methods for treating mammalian gastrointestinal microbial infections |
| GB0905667D0 (en) * | 2009-04-02 | 2009-05-20 | Summit Corp Plc | Compounds for treatment of duchenne muscular dystrophy |
| GB0905664D0 (en) * | 2009-04-02 | 2009-05-13 | Summit Corp Plc | Compounds for treatment of duchenne muscular dystrophy |
| US9186353B2 (en) | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
| JP2013505913A (ja) * | 2009-09-24 | 2013-02-21 | エフ.ホフマン−ラ ロシュ アーゲー | Crac調節剤としてのインドール誘導体 |
| JP5540640B2 (ja) | 2009-10-07 | 2014-07-02 | 住友化学株式会社 | 複素環化合物及びその有害節足動物防除用途 |
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| JO3192B1 (ar) | 2011-09-06 | 2018-03-08 | Novartis Ag | مركب بنزوثيازولون |
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| RU2015115677A (ru) | 2012-10-17 | 2016-12-10 | Ф. Хоффманн-Ля Рош Аг | Производные 6-аминоиндола в качестве антагонистов канала с транзиторным рецепторным потенциалом (trp) |
| ITMI20122065A1 (it) * | 2012-12-03 | 2014-06-04 | Univ Padova | Uso dei correttori del cftr nel trattamento delle patologie del muscolo striato |
| JP2016506929A (ja) * | 2013-01-23 | 2016-03-07 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ヒト銅輸送タンパク質atox1およびccsを阻害するための方法および組成物 |
| ES2847383T3 (es) | 2013-03-15 | 2021-08-03 | Atyr Pharma Inc | Conjugados de Fc-histidil-ARNt sintetasa |
| TWI652014B (zh) * | 2013-09-13 | 2019-03-01 | 美商艾佛艾姆希公司 | 雜環取代之雙環唑殺蟲劑 |
| ES2838625T3 (es) * | 2014-04-14 | 2021-07-02 | Shanghai hengrui pharmaceutical co ltd | Derivados de amida y sales farmacéuticamente aceptables de los mismos, su método de preparación y aplicación médica de los mismos |
| GB201412010D0 (en) | 2014-07-04 | 2014-08-20 | Summit Corp Plc | Treatment of hypertransaminasemia |
| US20170298081A1 (en) * | 2014-08-08 | 2017-10-19 | Kasuma Partners Inc. | Condensed heterocyclic compound |
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| US9371314B2 (en) | 2014-10-09 | 2016-06-21 | Allergan, Inc. | Pyridyl benzothiophenes as kinase inhibitors |
| JP6603035B2 (ja) * | 2015-03-31 | 2019-11-06 | セイカ株式会社 | アミノ基及び/又はニトロ基を有するベンゾオキサゾール−2−イル−ジフェニルエーテル及びその誘導体、並びにこれらの製造方法 |
| JP6603043B2 (ja) * | 2015-05-26 | 2019-11-06 | セイカ株式会社 | 芳香族ジアミン及びその中間体、並びにこれらの製造方法 |
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| EP3612215B1 (en) | 2017-04-20 | 2024-08-28 | aTyr Pharma, Inc. | Compositions for treating lung inflammation |
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| JP2023552638A (ja) * | 2020-12-11 | 2023-12-18 | ティーエムイーエム16エー リミテッド | 呼吸器疾患を治療するためのベンゾイミダゾール誘導体 |
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| CN114057662A (zh) * | 2021-12-10 | 2022-02-18 | 湖南第一师范学院 | 一种Tafamidis的合成方法 |
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