JP2009520695A5 - - Google Patents
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- Publication number
- JP2009520695A5 JP2009520695A5 JP2008545125A JP2008545125A JP2009520695A5 JP 2009520695 A5 JP2009520695 A5 JP 2009520695A5 JP 2008545125 A JP2008545125 A JP 2008545125A JP 2008545125 A JP2008545125 A JP 2008545125A JP 2009520695 A5 JP2009520695 A5 JP 2009520695A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- group
- solvate
- hydrate
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 27
- 150000003839 salts Chemical class 0.000 claims 11
- 239000012453 solvate Substances 0.000 claims 11
- 125000001072 heteroaryl group Chemical group 0.000 claims 10
- 125000003118 aryl group Chemical group 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000003107 substituted aryl group Chemical group 0.000 claims 2
- 125000006163 5-membered heteroaryl group Chemical group 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 230000003385 bacteriostatic effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 0 CC(*)(C1)C(*)C(C(NO)=O)N1C(*)=O Chemical compound CC(*)(C1)C(*)C(C(NO)=O)N1C(*)=O 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75060005P | 2005-12-15 | 2005-12-15 | |
| PCT/IB2006/003549 WO2007069020A2 (en) | 2005-12-15 | 2006-12-04 | N-hydroxyamide derivatives possessing antibacterial activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009520695A JP2009520695A (ja) | 2009-05-28 |
| JP2009520695A5 true JP2009520695A5 (enExample) | 2010-01-28 |
Family
ID=38163279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545125A Pending JP2009520695A (ja) | 2005-12-15 | 2006-12-04 | 抗菌活性を有するｎ−ヒドロキシアミド誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8088804B2 (enExample) |
| EP (2) | EP1963262A2 (enExample) |
| JP (1) | JP2009520695A (enExample) |
| CA (1) | CA2634005C (enExample) |
| WO (1) | WO2007069020A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101011373B1 (ko) | 2002-07-11 | 2011-01-28 | 비큐론 파마슈티컬스 인코포레이티드 | 항균작용을 갖는 ｎ-히드록시아미드 유도체 |
| EP2170814B1 (en) | 2007-06-12 | 2016-08-17 | Achaogen, Inc. | Antibacterial agents |
| EP2234608A2 (en) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
| JP5650642B2 (ja) * | 2008-08-01 | 2015-01-07 | バイオキシネス ファーマシューティカルズ， インコーポレイテッド | メチオニンアナログおよびそれらを使用する方法 |
| US8722686B2 (en) | 2008-09-19 | 2014-05-13 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| JP5746864B2 (ja) * | 2008-11-19 | 2015-07-08 | ポーラ化成工業株式会社 | シワ改善剤 |
| EP2488489A2 (en) * | 2009-10-13 | 2012-08-22 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| CA2899583A1 (en) | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| TWI543961B (zh) | 2010-04-20 | 2016-08-01 | 大正製藥股份有限公司 | Novel hydroxamic acid derivatives |
| KR101593288B1 (ko) * | 2011-03-07 | 2016-02-11 | 화이자 인코포레이티드 | 항균제로서 유용한 플루오로-피리디논 유도체 |
| CN103492368A (zh) | 2011-04-08 | 2014-01-01 | 辉瑞大药厂 | 用作抗菌剂的咪唑、吡唑和噻唑衍生物 |
| AU2012238374B2 (en) | 2011-04-08 | 2015-04-02 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| JP6006609B2 (ja) * | 2011-10-19 | 2016-10-12 | 大正製薬株式会社 | 新規なヒドロキサム酸誘導体を含有する医薬 |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| ES2728336T3 (es) | 2013-03-15 | 2019-10-23 | Fujifilm Toyama Chemical Co Ltd | Nuevo derivado de ácido hidroxámico o sal del mismo |
| EP2883876A1 (en) | 2013-12-16 | 2015-06-17 | Actelion Pharmaceuticals Ltd. | Stereoselective synthesis of substituted pyrrolidines |
| AU2015316401A1 (en) | 2014-09-12 | 2017-04-06 | Fujifilm Toyama Chemical Co., Ltd. | Novel pharmaceutical composition containing hydroxamic acid derivative or salt thereof |
| RU2017112303A (ru) | 2014-09-12 | 2018-10-12 | Тояма Кемикал Ко., Лтд. | Способ применения комбинации нового производного гидроксамовой кислоты и антибактериального вещества |
| CN108569991A (zh) * | 2018-05-31 | 2018-09-25 | 常州制药厂有限公司 | 一种抗丙肝病毒药物关键中间体的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4077998A (en) | 1975-10-28 | 1978-03-07 | Morton-Norwich Products, Inc. | Phthaloyl amino acid hydroxamic acids |
| KR100332273B1 (ko) * | 1995-07-26 | 2002-06-20 | 디. 제이. 우드, 스피겔 알렌 제이 | 엔-(아로일)글리신하이드록삼산유도체및이와관련된화합물 |
| CA2235986C (en) * | 1995-11-06 | 2006-09-12 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US6693123B2 (en) * | 1995-11-06 | 2004-02-17 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| WO1999006340A2 (en) | 1997-07-31 | 1999-02-11 | The Procter & Gamble Company | Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors |
| US6784173B2 (en) * | 2001-06-15 | 2004-08-31 | Hoffmann-La Roche Inc. | Aromatic dicarboxylic acid derivatives |
| KR101011373B1 (ko) | 2002-07-11 | 2011-01-28 | 비큐론 파마슈티컬스 인코포레이티드 | 항균작용을 갖는 ｎ-히드록시아미드 유도체 |
| AU2004204760C1 (en) * | 2003-01-08 | 2010-08-19 | Novartis Vaccines And Diagnostics, Inc. | Antibacterial agents |
| US7208601B2 (en) | 2003-08-08 | 2007-04-24 | Mjalli Adnan M M | Aryl and heteroaryl compounds, compositions, and methods of use |
| DE10348023A1 (de) * | 2003-10-15 | 2005-05-19 | Imtm Gmbh | Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
| JP2008508348A (ja) * | 2004-08-02 | 2008-03-21 | ジェンメディカ・セラピューティックス・ソシエダッド・リミターダ | 銅含有アミンオキシダーゼを阻害するための化合物およびその使用 |
| WO2006040646A1 (en) | 2004-10-14 | 2006-04-20 | Pfizer, Inc. | Benzimidazole or indole amides as inhibitors of pin1 |
| US20100152188A1 (en) | 2005-08-05 | 2010-06-17 | Akella Satya Surya Visweswara Srinivas | Novel Heterocyclic Compounds |
-
2006
- 2006-12-04 US US12/097,307 patent/US8088804B2/en not_active Expired - Fee Related
- 2006-12-04 WO PCT/IB2006/003549 patent/WO2007069020A2/en not_active Ceased
- 2006-12-04 EP EP06821047A patent/EP1963262A2/en not_active Withdrawn
- 2006-12-04 CA CA2634005A patent/CA2634005C/en not_active Expired - Fee Related
- 2006-12-04 JP JP2008545125A patent/JP2009520695A/ja active Pending
- 2006-12-04 EP EP11151502A patent/EP2338878A3/en not_active Withdrawn