JP2009520695A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009520695A5 JP2009520695A5 JP2008545125A JP2008545125A JP2009520695A5 JP 2009520695 A5 JP2009520695 A5 JP 2009520695A5 JP 2008545125 A JP2008545125 A JP 2008545125A JP 2008545125 A JP2008545125 A JP 2008545125A JP 2009520695 A5 JP2009520695 A5 JP 2009520695A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- group
- solvate
- hydrate
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 27
- 150000003839 salts Chemical class 0.000 claims 11
- 239000012453 solvate Substances 0.000 claims 11
- 125000001072 heteroaryl group Chemical group 0.000 claims 10
- 125000003118 aryl group Chemical group 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000003107 substituted aryl group Chemical group 0.000 claims 2
- 125000006163 5-membered heteroaryl group Chemical group 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 230000003385 bacteriostatic effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 0 CC(*)(C1)C(*)C(C(NO)=O)N1C(*)=O Chemical compound CC(*)(C1)C(*)C(C(NO)=O)N1C(*)=O 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75060005P | 2005-12-15 | 2005-12-15 | |
| PCT/IB2006/003549 WO2007069020A2 (en) | 2005-12-15 | 2006-12-04 | N-hydroxyamide derivatives possessing antibacterial activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009520695A JP2009520695A (ja) | 2009-05-28 |
| JP2009520695A5 true JP2009520695A5 (enExample) | 2010-01-28 |
Family
ID=38163279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545125A Pending JP2009520695A (ja) | 2005-12-15 | 2006-12-04 | 抗菌活性を有するｎ−ヒドロキシアミド誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8088804B2 (enExample) |
| EP (2) | EP1963262A2 (enExample) |
| JP (1) | JP2009520695A (enExample) |
| CA (1) | CA2634005C (enExample) |
| WO (1) | WO2007069020A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2492035A1 (en) | 2002-07-11 | 2004-01-15 | Vicuron Pharmaceuticals, Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| CA2691987C (en) | 2007-06-12 | 2016-08-16 | Achaogen, Inc. | Antibacterial agents |
| EP2234608A2 (en) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
| US8580859B2 (en) | 2008-08-01 | 2013-11-12 | Bioxiness Pharmaceuticals, Inc. | Methionine analogs and methods of using same |
| US8722686B2 (en) | 2008-09-19 | 2014-05-13 | Pfizer Inc. | Hydroxamic acid derivatives useful as antibacterial agents |
| CN102215812B (zh) * | 2008-11-19 | 2014-09-10 | 宝丽化成工业有限公司 | 抗皱剂 |
| CA2774250C (en) * | 2009-10-13 | 2013-12-17 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| JP5793766B2 (ja) | 2009-12-16 | 2015-10-14 | ファイザー・インク | 抗菌剤として有用なｎ−結合型ヒドロキサム酸誘導体 |
| RS59255B1 (sr) | 2010-04-20 | 2019-10-31 | Fujifilm Toyama Chemical Co Ltd | Derivat hidroksaminske kiseline |
| AP3336A (en) | 2011-03-07 | 2015-07-31 | Pfizer | Fluoro-pyridinone derivatives useful as antibacterial agents |
| WO2012137094A1 (en) | 2011-04-08 | 2012-10-11 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| WO2012137099A1 (en) * | 2011-04-08 | 2012-10-11 | Pfizer Inc. | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents |
| JP6006609B2 (ja) * | 2011-10-19 | 2016-10-12 | 大正製薬株式会社 | 新規なヒドロキサム酸誘導体を含有する医薬 |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| EP2975022B1 (en) | 2013-03-15 | 2019-05-08 | FUJIFILM Toyama Chemical Co., Ltd. | Novel hydroxamic acid derivative or salt thereof |
| EP2883876A1 (en) | 2013-12-16 | 2015-06-17 | Actelion Pharmaceuticals Ltd. | Stereoselective synthesis of substituted pyrrolidines |
| CA2960949A1 (en) | 2014-09-12 | 2016-03-17 | Tatsuya Honda | Novel pharmaceutical composition containing hydroxamic acid derivative or salt thereof |
| CN106794162A (zh) | 2014-09-12 | 2017-05-31 | 富山化学工业株式会社 | 组合使用新的异羟肟酸衍生物和抗菌性物质的方法 |
| CN108569991A (zh) * | 2018-05-31 | 2018-09-25 | 常州制药厂有限公司 | 一种抗丙肝病毒药物关键中间体的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4077998A (en) * | 1975-10-28 | 1978-03-07 | Morton-Norwich Products, Inc. | Phthaloyl amino acid hydroxamic acids |
| EP0850215B1 (en) * | 1995-07-26 | 2000-10-18 | Pfizer Inc. | N-(aroyl)glycine hydroxamic acid derivatives and related compounds |
| US6693123B2 (en) | 1995-11-06 | 2004-02-17 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
| ATE236632T1 (de) * | 1995-11-06 | 2003-04-15 | Univ Pittsburgh | Inhibitoren der protein-isoprenyl-transferase |
| US5925659A (en) | 1996-05-07 | 1999-07-20 | Merck & Co., Inc. | Antibacterial agents |
| CN1265647A (zh) | 1997-07-31 | 2000-09-06 | 普罗克特和甘保尔公司 | 无环金属蛋白酶抑制剂 |
| US6784173B2 (en) * | 2001-06-15 | 2004-08-31 | Hoffmann-La Roche Inc. | Aromatic dicarboxylic acid derivatives |
| CA2492035A1 (en) * | 2002-07-11 | 2004-01-15 | Vicuron Pharmaceuticals, Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
| ES2387803T3 (es) * | 2003-01-08 | 2012-10-02 | Novartis Vaccines And Diagnostics, Inc. | Agentes antibacterianos |
| US7208601B2 (en) | 2003-08-08 | 2007-04-24 | Mjalli Adnan M M | Aryl and heteroaryl compounds, compositions, and methods of use |
| DE10348023A1 (de) * | 2003-10-15 | 2005-05-19 | Imtm Gmbh | Neue Alanyl-Aminopeptidasen-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
| MX2007001337A (es) * | 2004-08-02 | 2008-03-13 | Genmedica Therapeutics Sl | Compuestos para inhibir amina-oxidasas que contienen cobre y usos de los mismos. |
| WO2006040646A1 (en) * | 2004-10-14 | 2006-04-20 | Pfizer, Inc. | Benzimidazole or indole amides as inhibitors of pin1 |
| WO2007017728A2 (en) | 2005-08-05 | 2007-02-15 | Orchid Research Laboratories Limited | Novel heterocyclic compounds |
-
2006
- 2006-12-04 JP JP2008545125A patent/JP2009520695A/ja active Pending
- 2006-12-04 US US12/097,307 patent/US8088804B2/en not_active Expired - Fee Related
- 2006-12-04 CA CA2634005A patent/CA2634005C/en not_active Expired - Fee Related
- 2006-12-04 WO PCT/IB2006/003549 patent/WO2007069020A2/en not_active Ceased
- 2006-12-04 EP EP06821047A patent/EP1963262A2/en not_active Withdrawn
- 2006-12-04 EP EP11151502A patent/EP2338878A3/en not_active Withdrawn