JP2003519676A5 - - Google Patents

Download PDF

Info

Publication number
JP2003519676A5
JP2003519676A5 JP2001551838A JP2001551838A JP2003519676A5 JP 2003519676 A5 JP2003519676 A5 JP 2003519676A5 JP 2001551838 A JP2001551838 A JP 2001551838A JP 2001551838 A JP2001551838 A JP 2001551838A JP 2003519676 A5 JP2003519676 A5 JP 2003519676A5
Authority
JP
Japan
Prior art keywords
group
alkyl
substituted
unsubstituted
heteroalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001551838A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003519676A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/001219 external-priority patent/WO2001051456A2/en
Publication of JP2003519676A publication Critical patent/JP2003519676A/ja
Publication of JP2003519676A5 publication Critical patent/JP2003519676A5/ja
Pending legal-status Critical Current

Links

JP2001551838A 2000-01-13 2001-01-12 抗菌剤 Pending JP2003519676A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17589200P 2000-01-13 2000-01-13
US60/175,892 2000-01-13
PCT/US2001/001219 WO2001051456A2 (en) 2000-01-13 2001-01-12 Antibacterial agents

Publications (2)

Publication Number Publication Date
JP2003519676A JP2003519676A (ja) 2003-06-24
JP2003519676A5 true JP2003519676A5 (enExample) 2008-02-07

Family

ID=22642090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001551838A Pending JP2003519676A (ja) 2000-01-13 2001-01-12 抗菌剤

Country Status (9)

Country Link
US (3) US6780858B2 (enExample)
EP (1) EP1246795B1 (enExample)
JP (1) JP2003519676A (enExample)
AT (1) ATE376996T1 (enExample)
AU (1) AU2001239725A1 (enExample)
CA (1) CA2397575A1 (enExample)
DE (1) DE60131138T2 (enExample)
ES (1) ES2293980T3 (enExample)
WO (1) WO2001051456A2 (enExample)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2397575A1 (en) 2000-01-13 2001-07-19 Tularik Inc. Antibacterial agents
AU2002326375B2 (en) 2001-03-08 2006-12-21 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers as anti-infective agents
MXPA04000224A (es) 2001-07-10 2005-07-25 4Sc Ag Novedosos compuestos como agentes antiinflamatorios, inmunomoduladores y antiproliferativos.
WO2003039529A1 (en) * 2001-11-07 2003-05-15 4Sc A.G. Selective antibacterial agents
US7335779B2 (en) 2002-03-08 2008-02-26 Quonova, Llc Modulation of pathogenicity
US7338969B2 (en) 2002-03-08 2008-03-04 Quonova, Llc Modulation of pathogenicity
US7589199B2 (en) * 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
DK1531822T3 (da) * 2002-06-12 2009-12-07 Chemocentryx Inc 1-aryl-4-substituerede piperazin derivater til anvendelse som CCR1 antagonister til behandlingen af inflammation og immunforstyrrelser
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
GB0215676D0 (en) 2002-07-05 2002-08-14 Novartis Ag Organic compounds
ATE402700T1 (de) * 2002-08-27 2008-08-15 Merck Patent Gmbh Glycinamid-derivate als raf-kinase-hemmer
US7589112B2 (en) * 2002-10-24 2009-09-15 Merck Patent Gmbh Methylene urea derivatives
US7078419B2 (en) 2003-03-10 2006-07-18 Boehringer Ingelheim Pharmaceuticals, Inc. Cytokine inhibitors
US9241917B2 (en) 2003-03-17 2016-01-26 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers and uses thereof
US20040242639A1 (en) * 2003-03-31 2004-12-02 Bharat Lagu Phospholipase C inhibitors for use in treating inflammatory disorders
WO2005020921A2 (en) 2003-08-29 2005-03-10 Exelixis, Inc. C-kit modulators and methods of use
US7932272B2 (en) 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
WO2005046683A1 (en) 2003-10-07 2005-05-26 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2005072246A2 (en) 2004-01-23 2005-08-11 The Trustees Of The University Of Pennsylvania Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
US7371743B2 (en) 2004-02-28 2008-05-13 Boehringer Ingelheim International Gmbh Carboxylic acid amides, the preparation thereof and their use as medicaments
US7435831B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
AU2005219438B2 (en) * 2004-03-03 2011-02-17 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
US7250413B2 (en) 2004-04-26 2007-07-31 Cumbre Pharmaceuticals Inc. C-25 carbamate rifamycin derivatives with activity against drug-resistant microbes
MX2007004248A (es) 2004-10-13 2007-06-12 Merck Patent Gmbh Derivados heterociclicos de bisarilurea sustituidos como inhibidores de cinasa.
WO2006082030A1 (en) * 2005-02-04 2006-08-10 Ctg Pharma S.R.L. New 4-aminoquinoline derivatives as antimalarials
US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2006106711A1 (ja) 2005-03-30 2006-10-12 Eisai R & D Management Co., Ltd. ピリジン誘導体を含有する抗真菌剤
DK1879573T3 (da) 2005-05-10 2013-02-25 Incyte Corp Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
US20090023813A1 (en) 2005-12-13 2009-01-22 Arpida Ag Diphenyl Urea Derivatives
ES2540561T3 (es) 2005-12-20 2015-07-10 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
CA2640678C (en) 2006-02-03 2015-03-31 Bionomics Limited Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors
US20070203140A1 (en) * 2006-02-09 2007-08-30 Combs Andrew P N-hydroxyguanidines as modulators of indoleamine 2,3-dioxygenase
US8168658B2 (en) 2006-02-28 2012-05-01 Merck Sharp & Dohme Corp. Inhibitors of histone deacetylase
US20080146624A1 (en) * 2006-09-19 2008-06-19 Incyte Corporation Amidines as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es) * 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
CA2663057C (en) 2006-09-19 2015-12-08 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
US20080182882A1 (en) * 2006-11-08 2008-07-31 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
US8093265B2 (en) 2007-03-09 2012-01-10 Renovis, Inc. Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
GB0718735D0 (en) * 2007-09-25 2007-11-07 Prolysis Ltd Antibacterial agents
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
GB2461167B (en) * 2008-06-24 2012-12-26 Scynexis Inc Novel amidoxime derivatives
CA3012229C (en) 2008-07-08 2020-11-10 Incyte Holdings Corporation 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
WO2010077734A2 (en) * 2008-12-09 2010-07-08 Cytokine Pharmasciences, Inc. Novel antiviral compounds, compositions, and methods of use
US20110275635A1 (en) * 2009-01-09 2011-11-10 The Uab Research Foundation Small molecule inhibitors of nads, namnat, and nmnat
US8362277B2 (en) 2009-01-09 2013-01-29 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9095572B2 (en) 2009-01-09 2015-08-04 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
CA2748813C (en) 2009-01-09 2018-07-10 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9962368B2 (en) 2009-01-09 2018-05-08 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9162980B2 (en) 2009-01-09 2015-10-20 Board Of Regents Of The University Of Texas System Anti-depression compounds
ES2458872T3 (es) 2009-04-30 2014-05-07 Novartis Ag Derivados de imidazol y su uso como moduladores de quinasas dependientes de ciclina
ES2663972T3 (es) 2012-01-10 2018-04-17 Merck Patent Gmbh Derivados de benzamida como moduladores de la hormona folículo estimulante
EP2887803A4 (en) 2012-08-24 2016-08-03 Univ Texas PRO-NEUROGENIC COMPOUNDS
CN104797429B (zh) * 2012-11-21 2017-04-19 日本曹达株式会社 使用非酚类化合物的记录材料、记录片和将非酚类化合物用于显色剂的方法
AR094929A1 (es) 2013-02-28 2015-09-09 Bristol Myers Squibb Co Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
EP2961746B1 (en) 2013-02-28 2018-01-03 Bristol-Myers Squibb Company Phenylpyrazole derivatives as potent rock1 and rock2 inhibitors
EP3744715A1 (en) 2013-11-08 2020-12-02 Incyte Holdings Corporation Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor
WO2015070237A1 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective chemicals and methods for identifying and using same
EP3068388A4 (en) 2013-11-11 2017-04-12 Board of Regents of the University of Texas System Neuroprotective compounds and use thereof
CN104725276B (zh) * 2013-12-18 2017-05-10 浙江省化工研究院有限公司 一种含七氟异丙基的羰基肟醚类化合物、其制备方法及应用
CN116761603A (zh) * 2021-02-06 2023-09-15 正大天晴药业集团股份有限公司 含有苯并杂环的作为egfr激酶抑制剂的大环化合物、其药物组合物和用途
MX2023014819A (es) 2021-06-14 2024-03-21 Scorpion Therapeutics Inc Derivados de la urea que pueden ser utilizados para tratar el cancer.
CN114773250A (zh) * 2021-08-02 2022-07-22 湖南大学 具有抗耐药性的抗菌脒类低聚物及其制作方法和用途
AR131715A1 (es) * 2023-01-30 2025-04-23 Eurofarma Laboratorios S A AMIDAS BLOQUEADORAS DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE LOS MISMOS Y KITS
WO2024159287A1 (pt) * 2023-01-30 2024-08-08 Eurofarma Laboratórios S.A. Hidroxamatos bloqueadores de nav 1.7 e/ou nav 1.8, seus processos de obtenção, composições, usos, métodos de tratamento destes e kits
EP4722193A1 (en) * 2024-10-04 2026-04-08 Technische Universität München, in Vertretung des Freistaats Bayern Compounds for use in the treatment of bacterial diseases and infections

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3347874A (en) * 1963-01-09 1967-10-17 Union Carbide Corp 5-nitrofuryl-2-amidoximes
JPS49124204A (enExample) * 1973-04-02 1974-11-28
DE2623228C3 (de) * 1976-05-24 1981-09-10 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren N-Acyl-substituierte Benzamide, Verfahren zu ihrer Herstellung und Arzneimittel, enthaltend solche Benzamide
DE2801509A1 (de) * 1978-01-12 1979-07-19 Schering Ag 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
JPS6434954A (en) * 1987-02-18 1989-02-06 Hokko Chem Ind Co Benzenecarboximidamide derivative and agricultural and horticultural fungicide
JPS63316703A (ja) * 1987-06-19 1988-12-26 Hokko Chem Ind Co Ltd 薬害軽減作用を有する農園芸用殺菌・除草剤
JPS6413071A (en) * 1987-07-07 1989-01-17 Fuji Photo Film Co Ltd Production of 3-alkoxy-5-amino-1h-pyrazoles
JPH01215994A (ja) * 1988-02-24 1989-08-29 Hokko Chem Ind Co Ltd 電解反応によるベンゼンカルボキシイミダミド誘導体の製造方法
JPH07122744B2 (ja) * 1988-12-15 1995-12-25 富士写真フイルム株式会社 マゼンタ色素形成カプラーおよびカラー画像形成方法
JPH02201358A (ja) * 1989-01-30 1990-08-09 Konica Corp 新規なシアンカプラーを含有するハロゲン化銀カラー写真感光材料
JPH03148267A (ja) * 1989-11-01 1991-06-25 Hokko Chem Ind Co Ltd １，２，４―オキサジアジン―５―オン誘導体および農園芸用殺菌剤
JPH1171336A (ja) * 1997-06-25 1999-03-16 Mitsubishi Chem Corp アミド誘導体
EP2196930B1 (en) * 1998-07-01 2011-03-23 The Trustees of The University of Pennsylvania Cavity induced allosteric modificatin of intermolecular interactions and methods of identifiying compounds that effect the same
NZ510588A (en) * 1998-09-18 2003-08-29 Abbott Gmbh & Co Pyrrolopyrimidines as protein kinase inhibitors
EP1142868A4 (en) * 1998-12-22 2004-09-29 Mitsubishi Chem Corp AMIDE DERIVATIVES
CA2397575A1 (en) 2000-01-13 2001-07-19 Tularik Inc. Antibacterial agents

Similar Documents

Publication Publication Date Title
RU2225389C2 (ru) Производные аминометилкарбоновой кислоты и фармацевтическая композиция на их основе
EP1325921A3 (en) Oxo or oxy-pyridine compounds as 5-HT4 receptor modulators
JP2002536445A5 (enExample)
JP2002513668A5 (enExample)
RU2001104339A (ru) Производные тиобензимидазола
JP2002536329A5 (enExample)
JP2006501181A5 (enExample)
RU92004336A (ru) Водорастворимые производные камптотецина, способ их получения, фармацевтическая композиция, способ ингибирования энзима топоизомеразы, промежуточные продукты
JP2002502874A5 (enExample)
JP2005538072A5 (enExample)
JP2006511484A5 (enExample)
JP2002527434A5 (enExample)
JP2004533444A5 (enExample)
JP2001525394A5 (enExample)
JP2007246474A5 (enExample)
JP2002527414A5 (enExample)
CA2539349A1 (en) 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
JP2003502367A5 (enExample)
JP2001514171A5 (enExample)
JP2009520695A5 (enExample)
CA2382247A1 (en) Azaindoles having serotonin receptor affinity
JP2003507380A5 (enExample)
JP2004521913A5 (enExample)
JP2001513567A5 (enExample)
JP2005526773A5 (enExample)