JP2003502367A5 - - Google Patents

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Publication number
JP2003502367A5
JP2003502367A5 JP2001504372A JP2001504372A JP2003502367A5 JP 2003502367 A5 JP2003502367 A5 JP 2003502367A5 JP 2001504372 A JP2001504372 A JP 2001504372A JP 2001504372 A JP2001504372 A JP 2001504372A JP 2003502367 A5 JP2003502367 A5 JP 2003502367A5
Authority
JP
Japan
Prior art keywords
group
compound
formula
aryl
dichlorobenzyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001504372A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003502367A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/017244 external-priority patent/WO2000078309A1/en
Publication of JP2003502367A publication Critical patent/JP2003502367A/ja
Publication of JP2003502367A5 publication Critical patent/JP2003502367A5/ja
Pending legal-status Critical Current

Links

JP2001504372A 1999-06-23 2000-06-22 インドール化合物 Pending JP2003502367A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14055899P 1999-06-23 1999-06-23
US60/140,558 1999-06-23
PCT/US2000/017244 WO2000078309A1 (en) 1999-06-23 2000-06-22 Indole compounds

Publications (2)

Publication Number Publication Date
JP2003502367A JP2003502367A (ja) 2003-01-21
JP2003502367A5 true JP2003502367A5 (enExample) 2007-08-23

Family

ID=22491792

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001504372A Pending JP2003502367A (ja) 1999-06-23 2000-06-22 インドール化合物

Country Status (7)

Country Link
US (1) US6469046B1 (enExample)
EP (1) EP1187607A4 (enExample)
JP (1) JP2003502367A (enExample)
AU (1) AU5633300A (enExample)
CO (1) CO5180605A1 (enExample)
HK (1) HK1044481A1 (enExample)
WO (1) WO2000078309A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
CO5370679A1 (es) 1999-06-01 2004-02-27 Smithkline Beecham Corp Inhibidores fab 1
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
ECSP003699A (es) 1999-10-08 2002-04-23 Smithkline Beecham Corp Inhibidores de fab i
DE60230934D1 (de) 2001-04-06 2009-03-05 Affinium Pharm Inc Fab-i-inhibitoren
EP1575951B1 (en) * 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
US8450307B2 (en) * 2004-06-04 2013-05-28 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
CA2632476A1 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
CA2644809A1 (en) 2006-03-02 2007-09-07 Astellas Pharma Inc. 17 .beta. hsd type 5 inhibitor
EP2687533B1 (en) 2006-07-20 2017-07-19 Debiopharm International SA Acrylamide derivatives as FAB I inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
US20130237535A1 (en) * 2010-11-08 2013-09-12 Nicholas D. Adams Fatty acid synthase inhibitors
KR101720885B1 (ko) 2012-06-19 2017-03-28 데비오팜 인터네셔날 에스 에이 (e)-n-메틸-n-((3-메틸벤조푸란-2-일)메틸)-3-(7-옥소-5,6,7,8-테트라히드로-1,8-나프티리딘-3-일)아크릴아미드의전구약물 유도체
EP3587406B1 (en) 2013-03-13 2021-01-27 Forma Therapeutics, Inc. 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (fasn) inhibitors for the treatment of cancer
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
US11690824B2 (en) 2018-04-10 2023-07-04 The General Hospital Corporation Antibacterial compounds
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
CN113382633A (zh) 2018-10-29 2021-09-10 福马治疗股份有限公司 (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式
MY203711A (en) 2019-02-14 2024-07-15 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
JP7418475B2 (ja) 2019-06-14 2024-01-19 デバイオファーム インターナショナル エス.エー. バイオフィルムが関与する細菌感染症を治療するための医薬及びその使用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482960A (en) * 1994-11-14 1996-01-09 Warner-Lambert Company Nonpeptide endothelin antagonists

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