JP2003502367A5 - - Google Patents

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Publication number
JP2003502367A5
JP2003502367A5 JP2001504372A JP2001504372A JP2003502367A5 JP 2003502367 A5 JP2003502367 A5 JP 2003502367A5 JP 2001504372 A JP2001504372 A JP 2001504372A JP 2001504372 A JP2001504372 A JP 2001504372A JP 2003502367 A5 JP2003502367 A5 JP 2003502367A5
Authority
JP
Japan
Prior art keywords
group
compound
formula
aryl
dichlorobenzyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001504372A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003502367A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/017244 external-priority patent/WO2000078309A1/en
Publication of JP2003502367A publication Critical patent/JP2003502367A/ja
Publication of JP2003502367A5 publication Critical patent/JP2003502367A5/ja
Pending legal-status Critical Current

Links

JP2001504372A 1999-06-23 2000-06-22 インドール化合物 Pending JP2003502367A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14055899P 1999-06-23 1999-06-23
US60/140,558 1999-06-23
PCT/US2000/017244 WO2000078309A1 (en) 1999-06-23 2000-06-22 Indole compounds

Publications (2)

Publication Number Publication Date
JP2003502367A JP2003502367A (ja) 2003-01-21
JP2003502367A5 true JP2003502367A5 (enExample) 2007-08-23

Family

ID=22491792

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001504372A Pending JP2003502367A (ja) 1999-06-23 2000-06-22 インドール化合物

Country Status (7)

Country Link
US (1) US6469046B1 (enExample)
EP (1) EP1187607A4 (enExample)
JP (1) JP2003502367A (enExample)
AU (1) AU5633300A (enExample)
CO (1) CO5180605A1 (enExample)
HK (1) HK1044481A1 (enExample)
WO (1) WO2000078309A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
AR024158A1 (es) 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
ES2231275T3 (es) 1999-10-08 2005-05-16 Affinium Pharmaceuticals, Inc. Inhibidores de fab i.
JP4387804B2 (ja) * 2001-04-06 2009-12-24 アフィニアム・ファーマシューティカルズ・インコーポレイテッド ＦａｂＩ阻害剤
PT1575951E (pt) * 2002-12-06 2014-09-15 Debiopharm Int Sa Compostos heterocíclicos, métodos para os preparar e sua utilização em terapia
EP1608377B1 (en) 2003-03-17 2008-10-01 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
US8450307B2 (en) * 2004-06-04 2013-05-28 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
US20090156578A1 (en) * 2005-12-05 2009-06-18 PAULS Henry 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents
MX2008011127A (es) * 2006-03-02 2008-10-31 Astellas Pharma Inc INHIBIDOR DE 17ß HSD TIPO 5.
EP2054422B1 (en) * 2006-07-20 2017-06-14 Debiopharm International SA Acrylamide derivatives as fab i inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
JP2013542960A (ja) * 2010-11-08 2013-11-28 グラクソスミスクライン、インテレクチュアル、プロパティー、ナンバー２、リミテッド 脂肪酸シンターゼ阻害剤
EP2861608B8 (en) 2012-06-19 2019-06-19 Debiopharm International SA Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
MX364895B (es) 2013-03-13 2019-05-10 Forma Therapeutics Inc Nuevos compuestos y composiciones para la inhibicion de fasn.
DK3419628T3 (da) 2016-02-26 2021-01-11 Debiopharm Int Sa Medikament til behandling af diabetiske fodinfektioner
WO2019199979A1 (en) * 2018-04-10 2019-10-17 The General Hospital Corporation Antibacterial compounds
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
CN113382633A (zh) 2018-10-29 2021-09-10 福马治疗股份有限公司 (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式
ES2944535T3 (es) 2019-02-14 2023-06-22 Debiopharm Int Sa Formulación de afabicina, método para preparar la misma
UA129222C2 (uk) 2019-06-14 2025-02-12 Дебіофарм Інтернешнл С.А. Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482960A (en) * 1994-11-14 1996-01-09 Warner-Lambert Company Nonpeptide endothelin antagonists

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