JP2009530424A5 - - Google Patents

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Publication number
JP2009530424A5
JP2009530424A5 JP2009509903A JP2009509903A JP2009530424A5 JP 2009530424 A5 JP2009530424 A5 JP 2009530424A5 JP 2009509903 A JP2009509903 A JP 2009509903A JP 2009509903 A JP2009509903 A JP 2009509903A JP 2009530424 A5 JP2009530424 A5 JP 2009530424A5
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JP
Japan
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JP2009509903A
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English (en)
Japanese (ja)
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JP2009530424A (ja
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Priority claimed from PCT/US2007/064569 external-priority patent/WO2007136921A2/en
Publication of JP2009530424A publication Critical patent/JP2009530424A/ja
Publication of JP2009530424A5 publication Critical patent/JP2009530424A5/ja
Withdrawn legal-status Critical Current

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JP2009509903A 2006-03-21 2007-03-21 小分子アポトーシスプロモーター Withdrawn JP2009530424A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78461206P 2006-03-21 2006-03-21
US85497506P 2006-10-27 2006-10-27
PCT/US2007/064569 WO2007136921A2 (en) 2006-03-21 2007-03-21 Small molecule apoptosis promoters

Publications (2)

Publication Number Publication Date
JP2009530424A JP2009530424A (ja) 2009-08-27
JP2009530424A5 true JP2009530424A5 (enExample) 2010-03-04

Family

ID=38723933

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009509903A Withdrawn JP2009530424A (ja) 2006-03-21 2007-03-21 小分子アポトーシスプロモーター

Country Status (8)

Country Link
US (3) US7807699B2 (enExample)
EP (1) EP1996184A4 (enExample)
JP (1) JP2009530424A (enExample)
AU (1) AU2007254033A1 (enExample)
BR (1) BRPI0708942A2 (enExample)
CA (1) CA2646186A1 (enExample)
MX (1) MX2008012053A (enExample)
WO (1) WO2007136921A2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5230865B2 (ja) 2004-07-15 2013-07-10 テトラロジック ファーマシューティカルズ コーポレーション Iap結合性化合物
MX2007007195A (es) 2004-12-20 2007-10-08 Genentech Inc Inhibidores de pirrolidina de iap.
EA012810B1 (ru) 2005-02-25 2009-12-30 Тетралоджик Фармасеутикалс Димерные ингибиторы ингибиторов белков апоптоза (iap)
WO2006122408A1 (en) 2005-05-18 2006-11-23 Aegera Therapeutics Inc. Bir domain binding compounds
AU2006308453B9 (en) 2005-10-25 2011-12-01 Pharmascience Inc. IAP BIR domain binding compounds
WO2007106192A2 (en) 2005-12-19 2007-09-20 Genentech, Inc. Inhibitors of iap
TWI504597B (zh) 2006-03-16 2015-10-21 Pharmascience Inc 結合於細胞凋亡抑制蛋白(iap)之桿狀病毒iap重複序列(bir)區域之化合物
MX2008012053A (es) * 2006-03-21 2008-12-17 Joyant Pharmaceuticals Inc Promotores de apoptosis de molecula pequeña.
BRPI0711591A2 (pt) 2006-05-16 2011-11-16 Aegera Therapeutics, Inc. composto de ligação de domìnio bir da iap
JP5452223B2 (ja) 2006-07-24 2014-03-26 テトラロジック ファーマシューティカルズ コーポレーション Iap阻害剤
MX2009000824A (es) 2006-07-24 2009-02-04 Tetralogic Pharmaceuticals Cor Antagonistas dimericos de las proteinas inhibidoras de la apoptosis.
WO2008014229A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
US20100143499A1 (en) * 2006-07-24 2010-06-10 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
NZ598890A (en) 2007-04-30 2013-10-25 Genentech Inc Inhibitors of iap
JP2010528587A (ja) * 2007-05-07 2010-08-26 テトラロジック ファーマシューティカルズ コーポレーション アポトーシス阻害タンパク質のアンタゴニストに対する感受性のバイオマーカーとしてTNFα遺伝子の発現を用いる方法
US8835393B2 (en) 2008-08-02 2014-09-16 Genentech, Inc. Inhibitors of IAP
US9394279B2 (en) 2009-06-11 2016-07-19 Abbvie Inc. Anti-viral compounds
US8283372B2 (en) * 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
UY32826A (es) 2009-08-04 2011-02-28 Takeda Pharmaceutical Compuestos heterocíclicos
EP2493879B1 (en) * 2009-10-28 2014-05-14 Joyant Pharmaceuticals, Inc. Dimeric smac mimetics
AU2010319927B2 (en) 2009-10-29 2015-01-22 Janssen Pharmaceutica Nv Alkynyl derivatives useful as DPP-1 inhibitors
NZ602368A (en) 2010-02-12 2014-10-31 Pharmascience Inc Iap bir domain binding compounds
UY33236A (es) 2010-02-25 2011-09-30 Novartis Ag Inhibidores dimericos de las iap
UY33794A (es) 2010-12-13 2012-07-31 Novartis Ag Inhibidores diméricos de las iap
WO2012083170A1 (en) * 2010-12-16 2012-06-21 Abbott Laboratories Anti-viral compounds
US20140163229A1 (en) * 2011-04-07 2014-06-12 Cornell University Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same
EP2882740B1 (en) * 2012-08-09 2017-03-01 Bristol-Myers Squibb Company Iap antagonists
PL405505A1 (pl) * 2013-09-30 2015-04-13 Warszawski Uniwersytet Medyczny Zastosowanie pochodnej kwasu diaminodikarboksylowego jako inhibitora aktywności biologicznej IL-15 I IL-2
RU2685505C1 (ru) * 2018-11-29 2019-04-19 Михаил Владимирович Овчинников Гетероциклические амиды тирозина, обладающие анальгетическим, противовоспалительным и противоотечным действием
AU2020252216B2 (en) * 2019-04-05 2026-02-26 Hepagene Therapeutics (HK) Limited Bivalent antagonists of inhibitors of apoptosis proteins
US20230056604A1 (en) 2020-01-20 2023-02-23 Astrazeneca Ab Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer
EP4308095A4 (en) 2021-03-15 2025-02-19 Maze Therapeutics, Inc. GLYCOGEN SYNTHASE 1 (GYS1) INHIBITORS AND METHODS OF USE THEREOF

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003086470A2 (en) 2002-04-17 2003-10-23 Deutsches Krebsforschungszentrum Smac-peptides as therapeutics against cancer and autoimmune diseases
EP1723122B1 (en) * 2004-03-01 2014-11-19 Board of Regents, The University of Texas System Dimeric small molecule potentiators of apoptosis
JP5230865B2 (ja) * 2004-07-15 2013-07-10 テトラロジック ファーマシューティカルズ コーポレーション Iap結合性化合物
AU2006308453B9 (en) * 2005-10-25 2011-12-01 Pharmascience Inc. IAP BIR domain binding compounds
TWI504597B (zh) * 2006-03-16 2015-10-21 Pharmascience Inc 結合於細胞凋亡抑制蛋白(iap)之桿狀病毒iap重複序列(bir)區域之化合物
MX2008012053A (es) * 2006-03-21 2008-12-17 Joyant Pharmaceuticals Inc Promotores de apoptosis de molecula pequeña.

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