JP2009530424A5 - - Google Patents
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- Publication number
- JP2009530424A5 JP2009530424A5 JP2009509903A JP2009509903A JP2009530424A5 JP 2009530424 A5 JP2009530424 A5 JP 2009530424A5 JP 2009509903 A JP2009509903 A JP 2009509903A JP 2009509903 A JP2009509903 A JP 2009509903A JP 2009530424 A5 JP2009530424 A5 JP 2009530424A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- independently
- ring
- alkyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78461206P | 2006-03-21 | 2006-03-21 | |
| US85497506P | 2006-10-27 | 2006-10-27 | |
| PCT/US2007/064569 WO2007136921A2 (en) | 2006-03-21 | 2007-03-21 | Small molecule apoptosis promoters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009530424A JP2009530424A (ja) | 2009-08-27 |
| JP2009530424A5 true JP2009530424A5 (enExample) | 2010-03-04 |
Family
ID=38723933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009509903A Withdrawn JP2009530424A (ja) | 2006-03-21 | 2007-03-21 | 小分子アポトーシスプロモーター |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7807699B2 (enExample) |
| EP (1) | EP1996184A4 (enExample) |
| JP (1) | JP2009530424A (enExample) |
| AU (1) | AU2007254033A1 (enExample) |
| BR (1) | BRPI0708942A2 (enExample) |
| CA (1) | CA2646186A1 (enExample) |
| MX (1) | MX2008012053A (enExample) |
| WO (1) | WO2007136921A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2475207T3 (es) | 2004-07-15 | 2014-07-10 | Tetralogic Pharmaceuticals Corporation | Compuestos de unión a IAP |
| DK1836201T4 (da) | 2004-12-20 | 2013-11-11 | Genentech Inc | Pyrrolidininhibitorer af IAP. |
| PL1851200T3 (pl) | 2005-02-25 | 2014-06-30 | Tetralogic Pharm Corp | Dimeryczne inhibitory IAP |
| EP1883627B1 (en) | 2005-05-18 | 2018-04-18 | Pharmascience Inc. | Bir domain binding compounds |
| KR20080067357A (ko) | 2005-10-25 | 2008-07-18 | 에게라 쎄라퓨틱스 인코포레이티드 | Ｉａｐ ｂｉｒ 도메인 결합 화합물 |
| CA2632807A1 (en) | 2005-12-19 | 2007-09-20 | Genentech, Inc. | Inhibitors of iap |
| TWI504597B (zh) | 2006-03-16 | 2015-10-21 | Pharmascience Inc | 結合於細胞凋亡抑制蛋白（ｉａｐ）之桿狀病毒ｉａｐ重複序列（ｂｉｒ）區域之化合物 |
| EP1996184A4 (en) * | 2006-03-21 | 2010-09-22 | Joyant Pharmaceuticals Inc | SMALL MOLECULAR APOPTOSIS PROMOTERS |
| WO2007131366A1 (en) | 2006-05-16 | 2007-11-22 | Aegera Therapeutics Inc. | Iap bir domain binding compounds |
| US20100143499A1 (en) * | 2006-07-24 | 2010-06-10 | Tetralogic Pharmaceuticals Corporation | Dimeric iap inhibitors |
| EP2049524A2 (en) | 2006-07-24 | 2009-04-22 | Tetralogic Pharmaceuticals Corporation | Iap inhibitors |
| WO2008014263A2 (en) | 2006-07-24 | 2008-01-31 | Tetralogic Pharmaceuticals Corporation | Dimeric iap antagonists |
| WO2008014229A2 (en) * | 2006-07-24 | 2008-01-31 | Tetralogic Pharmaceuticals Corporation | Dimeric iap inhibitors |
| TWI432212B (zh) | 2007-04-30 | 2014-04-01 | Genentech Inc | Ｉａｐ抑制劑 |
| US20110008802A1 (en) * | 2007-05-07 | 2011-01-13 | Tetralogic Pharmaceuticals Corp. | TNFalpha GENE EXPRESSION AS A BIOMARKER OF SENSITIVITY TO ANTAGONISTS OF INHIBITOR OF APOPTOSIS PROTEINS |
| JP2011529962A (ja) | 2008-08-02 | 2011-12-15 | ジェネンテック， インコーポレイテッド | Ｉａｐのインヒビター |
| US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
| US8283372B2 (en) | 2009-07-02 | 2012-10-09 | Tetralogic Pharmaceuticals Corp. | 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic |
| US20110034469A1 (en) | 2009-08-04 | 2011-02-10 | Takeda Pharmaceutical Company Limited | Heterocyclic Compound |
| JP5529282B2 (ja) | 2009-10-28 | 2014-06-25 | ジョイアント ファーマスーティカルズ、インク． | 二量体Ｓｍａｃ模倣薬 |
| AU2010319927B2 (en) | 2009-10-29 | 2015-01-22 | Janssen Pharmaceutica Nv | Alkynyl derivatives useful as DPP-1 inhibitors |
| SG182724A1 (en) | 2010-02-12 | 2012-08-30 | Pharmascience Inc | Iap bir domain binding compounds |
| UY33236A (es) | 2010-02-25 | 2011-09-30 | Novartis Ag | Inhibidores dimericos de las iap |
| UY33794A (es) | 2010-12-13 | 2012-07-31 | Novartis Ag | Inhibidores diméricos de las iap |
| EP2651885A1 (en) * | 2010-12-16 | 2013-10-23 | Abbvie Inc. | Anti-viral compounds |
| WO2013058825A1 (en) * | 2011-04-07 | 2013-04-25 | Cornell University | Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same |
| EP2882740B1 (en) * | 2012-08-09 | 2017-03-01 | Bristol-Myers Squibb Company | Iap antagonists |
| PL405505A1 (pl) * | 2013-09-30 | 2015-04-13 | Warszawski Uniwersytet Medyczny | Zastosowanie pochodnej kwasu diaminodikarboksylowego jako inhibitora aktywności biologicznej IL-15 I IL-2 |
| RU2685505C1 (ru) * | 2018-11-29 | 2019-04-19 | Михаил Владимирович Овчинников | Гетероциклические амиды тирозина, обладающие анальгетическим, противовоспалительным и противоотечным действием |
| AU2020252216B2 (en) * | 2019-04-05 | 2026-02-26 | Hepagene Therapeutics (HK) Limited | Bivalent antagonists of inhibitors of apoptosis proteins |
| CA3166980A1 (en) | 2020-01-20 | 2021-07-29 | Astrazeneca Ab | Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer |
| MX2023009857A (es) | 2021-03-15 | 2024-01-03 | Maze Therapeutics Inc | Inhibidores de la glucogeno sintasa 1 (gys1) y metodos de uso de los mismos. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003086470A2 (en) | 2002-04-17 | 2003-10-23 | Deutsches Krebsforschungszentrum | Smac-peptides as therapeutics against cancer and autoimmune diseases |
| US7309792B2 (en) * | 2004-03-01 | 2007-12-18 | Board Of Regents, The University Of Texas System | Dimeric small molecule potentiators of apoptosis |
| ES2475207T3 (es) * | 2004-07-15 | 2014-07-10 | Tetralogic Pharmaceuticals Corporation | Compuestos de unión a IAP |
| KR20080067357A (ko) * | 2005-10-25 | 2008-07-18 | 에게라 쎄라퓨틱스 인코포레이티드 | Ｉａｐ ｂｉｒ 도메인 결합 화합물 |
| TWI504597B (zh) * | 2006-03-16 | 2015-10-21 | Pharmascience Inc | 結合於細胞凋亡抑制蛋白（ｉａｐ）之桿狀病毒ｉａｐ重複序列（ｂｉｒ）區域之化合物 |
| EP1996184A4 (en) * | 2006-03-21 | 2010-09-22 | Joyant Pharmaceuticals Inc | SMALL MOLECULAR APOPTOSIS PROMOTERS |
-
2007
- 2007-03-21 EP EP07759058A patent/EP1996184A4/en not_active Withdrawn
- 2007-03-21 US US11/726,602 patent/US7807699B2/en not_active Expired - Fee Related
- 2007-03-21 WO PCT/US2007/064569 patent/WO2007136921A2/en not_active Ceased
- 2007-03-21 AU AU2007254033A patent/AU2007254033A1/en not_active Abandoned
- 2007-03-21 CA CA002646186A patent/CA2646186A1/en not_active Abandoned
- 2007-03-21 BR BRPI0708942-2A patent/BRPI0708942A2/pt not_active IP Right Cessation
- 2007-03-21 MX MX2008012053A patent/MX2008012053A/es unknown
- 2007-03-21 JP JP2009509903A patent/JP2009530424A/ja not_active Withdrawn
-
2010
- 2010-10-04 US US12/897,760 patent/US8222291B2/en not_active Expired - Fee Related
-
2012
- 2012-06-28 US US13/536,974 patent/US8586542B2/en not_active Expired - Fee Related
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