JP2009530424A5 - - Google Patents

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Publication number
JP2009530424A5
JP2009530424A5 JP2009509903A JP2009509903A JP2009530424A5 JP 2009530424 A5 JP2009530424 A5 JP 2009530424A5 JP 2009509903 A JP2009509903 A JP 2009509903A JP 2009509903 A JP2009509903 A JP 2009509903A JP 2009530424 A5 JP2009530424 A5 JP 2009530424A5
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JP
Japan
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JP2009509903A
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English (en)
Japanese (ja)
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JP2009530424A (ja
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Priority claimed from PCT/US2007/064569 external-priority patent/WO2007136921A2/en
Publication of JP2009530424A publication Critical patent/JP2009530424A/ja
Publication of JP2009530424A5 publication Critical patent/JP2009530424A5/ja
Withdrawn legal-status Critical Current

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JP2009509903A 2006-03-21 2007-03-21 小分子アポトーシスプロモーター Withdrawn JP2009530424A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78461206P 2006-03-21 2006-03-21
US85497506P 2006-10-27 2006-10-27
PCT/US2007/064569 WO2007136921A2 (en) 2006-03-21 2007-03-21 Small molecule apoptosis promoters

Publications (2)

Publication Number Publication Date
JP2009530424A JP2009530424A (ja) 2009-08-27
JP2009530424A5 true JP2009530424A5 (enExample) 2010-03-04

Family

ID=38723933

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009509903A Withdrawn JP2009530424A (ja) 2006-03-21 2007-03-21 小分子アポトーシスプロモーター

Country Status (8)

Country Link
US (3) US7807699B2 (enExample)
EP (1) EP1996184A4 (enExample)
JP (1) JP2009530424A (enExample)
AU (1) AU2007254033A1 (enExample)
BR (1) BRPI0708942A2 (enExample)
CA (1) CA2646186A1 (enExample)
MX (1) MX2008012053A (enExample)
WO (1) WO2007136921A2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1773766B1 (en) * 2004-07-15 2014-04-02 Tetralogic Pharmaceuticals Corporation Iap binding compounds
ATE477254T1 (de) 2004-12-20 2010-08-15 Genentech Inc Pyrrolidine als inhibitoren von iap
BRPI0607988A2 (pt) 2005-02-25 2009-10-27 Tetralogic Pharmaceuticals composto, composição farmacêutica, e método para induzir apoptose em uma célula
US7772177B2 (en) 2005-05-18 2010-08-10 Aegera Therapeutics, Inc. BIR domain binding compounds
JP2009512719A (ja) 2005-10-25 2009-03-26 アエゲラ セラピューティクス インコーポレイテッド Ｉａｐｂｉｒドメイン結合化合物
CN101374829A (zh) 2005-12-19 2009-02-25 健泰科生物技术公司 Iap的抑制剂
TWI543988B (zh) 2006-03-16 2016-08-01 科學製藥股份有限公司 結合於細胞凋亡抑制蛋白（ｉａｐ）之桿狀病毒ｉａｐ重複序列（ｂｉｒ）區域之化合物
CA2646186A1 (en) * 2006-03-21 2007-11-29 Joyant Pharmaceuticals, Inc. Small molecule apoptosis promoters
AU2007250443B2 (en) 2006-05-16 2013-06-13 Pharmascience Inc. IAP BIR domain binding compounds
WO2008014238A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
US20100144650A1 (en) * 2006-07-24 2010-06-10 Tetralogic Pharmaceuticals Corporation Dimeric iap inhibitors
WO2008014252A2 (en) 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Iap inhibitors
AR063943A1 (es) 2006-07-24 2009-03-04 Tetralogic Pharmaceuticals Cor Dipeptidos antagonistas de iap, una composicion farmaceutica que los comprende y el uso de los mismos para el tratamiento del cancer.
CN101687787A (zh) 2007-04-30 2010-03-31 健泰科生物技术公司 Iap的抑制剂
JP2010528587A (ja) * 2007-05-07 2010-08-26 テトラロジック ファーマシューティカルズ コーポレーション アポトーシス阻害タンパク質のアンタゴニストに対する感受性のバイオマーカーとしてＴＮＦα遺伝子の発現を用いる方法
NZ590550A (en) 2008-08-02 2013-05-31 Genentech Inc Inhibitors of Apoptosis (IAP) for treating cancer
US9394279B2 (en) 2009-06-11 2016-07-19 Abbvie Inc. Anti-viral compounds
US8283372B2 (en) 2009-07-02 2012-10-09 Tetralogic Pharmaceuticals Corp. 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic
TW201109335A (en) 2009-08-04 2011-03-16 Takeda Pharmaceutical Heterocyclic compounds
WO2011059763A2 (en) 2009-10-28 2011-05-19 Joyant Pharmaceuticals, Inc. Dimeric smac mimetics
ES2513291T3 (es) 2009-10-29 2014-10-24 Janssen Pharmaceutica Nv Derivados alquinilo útiles como inhibidores de la DPP-1
EP2534170B1 (en) 2010-02-12 2017-04-19 Pharmascience Inc. Iap bir domain binding compounds
UY33236A (es) 2010-02-25 2011-09-30 Novartis Ag Inhibidores dimericos de las iap
UY33794A (es) 2010-12-13 2012-07-31 Novartis Ag Inhibidores diméricos de las iap
JP5906253B2 (ja) * 2010-12-16 2016-04-20 アッヴィ・インコーポレイテッド 抗ウイルス性化合物
WO2013058825A1 (en) * 2011-04-07 2013-04-25 Cornell University Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same
WO2014025759A1 (en) * 2012-08-09 2014-02-13 Bristol-Myers Squibb Company Iap antagonists
PL405505A1 (pl) * 2013-09-30 2015-04-13 Warszawski Uniwersytet Medyczny Zastosowanie pochodnej kwasu diaminodikarboksylowego jako inhibitora aktywności biologicznej IL-15 I IL-2
RU2685505C1 (ru) * 2018-11-29 2019-04-19 Михаил Владимирович Овчинников Гетероциклические амиды тирозина, обладающие анальгетическим, противовоспалительным и противоотечным действием
US20220220152A1 (en) * 2019-04-05 2022-07-14 Hepagene Therapeutics (HK) Limited Bivalent antagonists of inhibitors of apoptosis proteins
WO2021148396A1 (en) 2020-01-20 2021-07-29 Astrazeneca Ab Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer
WO2022198196A1 (en) 2021-03-15 2022-09-22 Maze Therapeutics, Inc. Inhibitors of glycogen synthase 1 (gys1) and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1495124A2 (en) 2002-04-17 2005-01-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
CA2582734C (en) * 2004-03-01 2011-05-03 Board Of Regents, The University Of Texas System Dimeric small molecule potentiators of apoptosis
EP1773766B1 (en) * 2004-07-15 2014-04-02 Tetralogic Pharmaceuticals Corporation Iap binding compounds
JP2009512719A (ja) * 2005-10-25 2009-03-26 アエゲラ セラピューティクス インコーポレイテッド Ｉａｐｂｉｒドメイン結合化合物
TWI543988B (zh) * 2006-03-16 2016-08-01 科學製藥股份有限公司 結合於細胞凋亡抑制蛋白（ｉａｐ）之桿狀病毒ｉａｐ重複序列（ｂｉｒ）區域之化合物
CA2646186A1 (en) * 2006-03-21 2007-11-29 Joyant Pharmaceuticals, Inc. Small molecule apoptosis promoters

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