JP2010529147A5 - - Google Patents

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JP2010529147A5
JP2010529147A5 JP2010511418A JP2010511418A JP2010529147A5 JP 2010529147 A5 JP2010529147 A5 JP 2010529147A5 JP 2010511418 A JP2010511418 A JP 2010511418A JP 2010511418 A JP2010511418 A JP 2010511418A JP 2010529147 A5 JP2010529147 A5 JP 2010529147A5
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JP
Japan
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compound
membered heterocycle
halogen
och
cho
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JP2010511418A
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Japanese (ja)
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JP4827986B2 (ja
JP2010529147A (ja
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Priority claimed from PCT/US2008/066310 external-priority patent/WO2008154484A1/en
Publication of JP2010529147A publication Critical patent/JP2010529147A/ja
Publication of JP2010529147A5 publication Critical patent/JP2010529147A5/ja
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Publication of JP4827986B2 publication Critical patent/JP4827986B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010511418A 2007-06-08 2008-06-09 IRE−1αインヒビター Expired - Fee Related JP4827986B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94274307P 2007-06-08 2007-06-08
US60/942,743 2007-06-08
PCT/US2008/066310 WO2008154484A1 (en) 2007-06-08 2008-06-09 Ire-1a inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011012200A Division JP5684585B2 (ja) 2007-06-08 2011-01-24 IRE−1αインヒビター

Publications (3)

Publication Number Publication Date
JP2010529147A JP2010529147A (ja) 2010-08-26
JP2010529147A5 true JP2010529147A5 (Direct) 2011-03-10
JP4827986B2 JP4827986B2 (ja) 2011-11-30

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ID=39730581

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2010511418A Expired - Fee Related JP4827986B2 (ja) 2007-06-08 2008-06-09 IRE−1αインヒビター
JP2011012200A Expired - Fee Related JP5684585B2 (ja) 2007-06-08 2011-01-24 IRE−1αインヒビター
JP2013169387A Ceased JP2014055129A (ja) 2007-06-08 2013-08-19 IRE−1αインヒビター
JP2015005455A Expired - Fee Related JP5941173B2 (ja) 2007-06-08 2015-01-15 IRE−1αインヒビター

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2011012200A Expired - Fee Related JP5684585B2 (ja) 2007-06-08 2011-01-24 IRE−1αインヒビター
JP2013169387A Ceased JP2014055129A (ja) 2007-06-08 2013-08-19 IRE−1αインヒビター
JP2015005455A Expired - Fee Related JP5941173B2 (ja) 2007-06-08 2015-01-15 IRE−1αインヒビター

Country Status (8)

Country Link
US (5) US7858666B2 (Direct)
EP (4) EP2532643A1 (Direct)
JP (4) JP4827986B2 (Direct)
CN (2) CN102015606B (Direct)
CA (2) CA2690913C (Direct)
ES (2) ES2569660T3 (Direct)
MX (1) MX2009013332A (Direct)
WO (1) WO2008154484A1 (Direct)

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CN106822904B (zh) * 2017-03-08 2019-10-25 暨南大学 含akt抑制剂和ire1抑制剂的药物组合物及其应用
CN107308178B (zh) * 2017-07-31 2020-11-10 苏州大学附属儿童医院 一种用于肠外营养相关性肝病药物
MX2020009566A (es) * 2018-03-27 2020-11-09 Neuropore Therapies Inc Compuestos como moduladores de la se?alizacion de tlr2.
MA53105A (fr) 2018-07-03 2021-05-12 Univ Illinois Activateurs de la réponse à une protéine non dépliée
US20210260069A1 (en) * 2018-07-23 2021-08-26 Fosun Orinove Pharmatech, Inc. IRE1a INHIBITOR IN COMBINATION WITH CANCER THERAPEUTIC AGENT FOR CANCER TREATMENT
WO2020019107A1 (en) * 2018-07-23 2020-01-30 Fosun Orinove Pharmatech, Inc. IRE1α INHIBITOR IN COMBINATION WITH CANCER THERAPEUTIC AGENT FOR CANCER TREATMENT
KR20210087972A (ko) * 2018-11-02 2021-07-13 포선 오리노브 파마테크, 인코포레이티드 암 치료를 위한 암 치료제와 병용된 IRE1α 억제제
BR112021018918A2 (pt) 2019-03-26 2021-12-07 Neuropore Therapies Inc Compostos e composições como moduladores de sinalização de tlr
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
CN118576600A (zh) * 2024-05-31 2024-09-03 中山大学附属第三医院 IRE1α抑制剂KIRA8在制备治疗复发难治多发性骨髓瘤的药物中的应用

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