MA53105A - Activateurs de la réponse à une protéine non dépliée - Google Patents
Activateurs de la réponse à une protéine non dépliéeInfo
- Publication number
- MA53105A MA53105A MA053105A MA53105A MA53105A MA 53105 A MA53105 A MA 53105A MA 053105 A MA053105 A MA 053105A MA 53105 A MA53105 A MA 53105A MA 53105 A MA53105 A MA 53105A
- Authority
- MA
- Morocco
- Prior art keywords
- activators
- response
- unfolded protein
- unfolded
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862693641P | 2018-07-03 | 2018-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA53105A true MA53105A (fr) | 2021-05-12 |
Family
ID=69059783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA053105A MA53105A (fr) | 2018-07-03 | 2019-07-01 | Activateurs de la réponse à une protéine non dépliée |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US20210276951A1 (fr) |
| EP (1) | EP3817741A4 (fr) |
| JP (1) | JP2021529757A (fr) |
| KR (1) | KR20210027382A (fr) |
| CN (1) | CN112423743A (fr) |
| AU (1) | AU2019299221A1 (fr) |
| BR (1) | BR112020025591A2 (fr) |
| CA (1) | CA3103958A1 (fr) |
| CL (1) | CL2020003423A1 (fr) |
| CO (1) | CO2020016690A2 (fr) |
| CR (1) | CR20210060A (fr) |
| DO (1) | DOP2020000256A (fr) |
| EA (1) | EA202190146A1 (fr) |
| EC (1) | ECSP20084330A (fr) |
| IL (1) | IL279429A (fr) |
| JO (1) | JOP20200344A1 (fr) |
| MA (1) | MA53105A (fr) |
| MX (1) | MX2021000043A (fr) |
| PE (1) | PE20210662A1 (fr) |
| PH (1) | PH12020552223A1 (fr) |
| SG (1) | SG11202012902WA (fr) |
| WO (1) | WO2020009958A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3817741A4 (fr) | 2018-07-03 | 2022-07-06 | The Board of Trustees of the University of Illinois | Activateurs de la réponse à une protéine non dépliée |
| WO2021222738A1 (fr) * | 2020-05-01 | 2021-11-04 | The Board Of Trustees Of The University Of Illinois | Composés pour cancers positifs au récepteur des oestrogènes |
| WO2022020605A1 (fr) * | 2020-07-23 | 2022-01-27 | The Board Of Trustees Of The University Of Illinois | Traitement du cancer du sein positif aux récepteurs des œstrogènes metastasé |
| WO2022032146A1 (fr) * | 2020-08-07 | 2022-02-10 | Systems Oncology, Llc | Procédés d'inhibition de la croissance de cancers era positifs |
| AU2021366688A1 (en) * | 2020-10-23 | 2023-05-25 | The Board Of Trustees Of The University Of Illinois | Anticancer compounds selective for er-positive cancers |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003078394A1 (fr) | 2002-03-15 | 2003-09-25 | Eli Lilly And Company | Derives de dihydroindol-2-one modulant le recepteur nucleaire de l'hormone steroide |
| US20050070718A1 (en) | 2003-09-30 | 2005-03-31 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| JP4989976B2 (ja) * | 2004-02-13 | 2012-08-01 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 翻訳開始阻害剤としての３−３−二置換オキシインドール |
| US7517899B2 (en) | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| BRPI0509745A (pt) * | 2004-04-08 | 2007-09-25 | Topotarget As | compostos de difenil ox-indol-2-ona e seu uso no tratamento de cáncer |
| WO2007041023A1 (fr) | 2005-09-29 | 2007-04-12 | Wyeth | Derives de 1- (1h- indol- 1-yl) -3- (methylamino) -1- phenylpropan-2-ol et composes associes utilises comme modulateurs du recaptage de monoamine pour traiter des symptomes vasomoteurs (vms) |
| TW200817382A (en) | 2006-08-24 | 2008-04-16 | Wyeth Corp | Process for preparing indolinone phenylaminopropanol derivatives |
| WO2008071387A1 (fr) * | 2006-12-11 | 2008-06-19 | Topotarget A/S | Pro-médicaments de composés diphényl ox-indol-2-one pour le traitement de cancers |
| EP2139856A1 (fr) * | 2007-04-24 | 2010-01-06 | Topotarget A/S | Composés 3-(4-hydroxyphényl)-indolin-2-one substitués |
| US7858666B2 (en) | 2007-06-08 | 2010-12-28 | Mannkind Corporation | IRE-1α inhibitors |
| WO2010109008A1 (fr) | 2009-03-26 | 2010-09-30 | Topotarget A/S | Promédicaments de 3-(4-hydroxyphényl)-indolin-2-ones substitués |
| WO2014047437A1 (fr) | 2012-09-20 | 2014-03-27 | President And Fellows Of Harvard College | Oxindoles 3,3-di-substitués en tant qu'inhibiteurs de l'initiation de la traduction |
| US9316631B1 (en) | 2012-10-19 | 2016-04-19 | Whitehead Institute For Biomedical Research | ER-stress inducing compounds and methods of use thereof |
| CA2898732A1 (fr) * | 2013-01-18 | 2014-07-24 | Mao CHENGJIAN | Inhibiteurs d'un recepteur des strogenes |
| AU2014233520B2 (en) | 2013-03-15 | 2019-02-21 | The Regents Of The University Of California | Modulators of the eIF2alpha pathway |
| PE20160874A1 (es) | 2013-05-28 | 2016-09-04 | Astrazeneca Ab | Compuestos quimicos |
| EP3817741A4 (fr) | 2018-07-03 | 2022-07-06 | The Board of Trustees of the University of Illinois | Activateurs de la réponse à une protéine non dépliée |
-
2019
- 2019-07-01 EP EP19831532.7A patent/EP3817741A4/fr not_active Withdrawn
- 2019-07-01 KR KR1020217001833A patent/KR20210027382A/ko unknown
- 2019-07-01 CA CA3103958A patent/CA3103958A1/fr not_active Abandoned
- 2019-07-01 MX MX2021000043A patent/MX2021000043A/es unknown
- 2019-07-01 AU AU2019299221A patent/AU2019299221A1/en not_active Abandoned
- 2019-07-01 JP JP2020573046A patent/JP2021529757A/ja active Pending
- 2019-07-01 JO JOP/2020/0344A patent/JOP20200344A1/ar unknown
- 2019-07-01 BR BR112020025591-2A patent/BR112020025591A2/pt not_active IP Right Cessation
- 2019-07-01 SG SG11202012902WA patent/SG11202012902WA/en unknown
- 2019-07-01 MA MA053105A patent/MA53105A/fr unknown
- 2019-07-01 CN CN201980045131.2A patent/CN112423743A/zh active Pending
- 2019-07-01 CR CR20210060A patent/CR20210060A/es unknown
- 2019-07-01 US US17/254,771 patent/US20210276951A1/en active Pending
- 2019-07-01 WO PCT/US2019/040058 patent/WO2020009958A1/fr active Application Filing
- 2019-07-01 EA EA202190146A patent/EA202190146A1/ru unknown
- 2019-07-01 PE PE2020002206A patent/PE20210662A1/es unknown
-
2020
- 2020-02-26 US US16/801,839 patent/US11046647B2/en active Active
- 2020-12-14 IL IL279429A patent/IL279429A/en unknown
- 2020-12-19 PH PH12020552223A patent/PH12020552223A1/en unknown
- 2020-12-29 CL CL2020003423A patent/CL2020003423A1/es unknown
- 2020-12-29 DO DO2020000256A patent/DOP2020000256A/es unknown
- 2020-12-29 EC ECSENADI202084330A patent/ECSP20084330A/es unknown
- 2020-12-30 CO CONC2020/0016690A patent/CO2020016690A2/es unknown
-
2021
- 2021-05-13 US US17/319,447 patent/US11584718B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3817741A4 (fr) | 2022-07-06 |
| EA202190146A1 (ru) | 2021-04-27 |
| US11584718B2 (en) | 2023-02-21 |
| DOP2020000256A (es) | 2021-03-15 |
| WO2020009958A1 (fr) | 2020-01-09 |
| ECSP20084330A (es) | 2021-01-29 |
| AU2019299221A1 (en) | 2021-02-04 |
| MX2021000043A (es) | 2021-03-25 |
| EP3817741A1 (fr) | 2021-05-12 |
| KR20210027382A (ko) | 2021-03-10 |
| CA3103958A1 (fr) | 2020-01-09 |
| BR112020025591A2 (pt) | 2021-03-23 |
| CR20210060A (es) | 2021-04-08 |
| PH12020552223A1 (en) | 2021-06-28 |
| CN112423743A (zh) | 2021-02-26 |
| IL279429A (en) | 2021-01-31 |
| JOP20200344A1 (ar) | 2020-12-31 |
| US11046647B2 (en) | 2021-06-29 |
| JP2021529757A (ja) | 2021-11-04 |
| CL2020003423A1 (es) | 2021-05-14 |
| CO2020016690A2 (es) | 2021-01-18 |
| SG11202012902WA (en) | 2021-01-28 |
| US20210340100A1 (en) | 2021-11-04 |
| US20210276951A1 (en) | 2021-09-09 |
| PE20210662A1 (es) | 2021-03-31 |
| US20200190029A1 (en) | 2020-06-18 |
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