MA52884A - Anticorps anti-il-11 - Google Patents

Anticorps anti-il-11

Info

Publication number
MA52884A
MA52884A MA052884A MA52884A MA52884A MA 52884 A MA52884 A MA 52884A MA 052884 A MA052884 A MA 052884A MA 52884 A MA52884 A MA 52884A MA 52884 A MA52884 A MA 52884A
Authority
MA
Morocco
Prior art keywords
antibodies
Prior art date
Application number
MA052884A
Other languages
English (en)
Inventor
Stuart Alexander Cook
Sebastian Schaefer
Original Assignee
Boehringer Ingelheim Int
Nat Univ Singapore
Singapore Health Serv Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Nat Univ Singapore, Singapore Health Serv Pte Ltd filed Critical Boehringer Ingelheim Int
Publication of MA52884A publication Critical patent/MA52884A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA052884A 2018-06-13 2019-06-13 Anticorps anti-il-11 MA52884A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1809699.0A GB201809699D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies

Publications (1)

Publication Number Publication Date
MA52884A true MA52884A (fr) 2021-04-21

Family

ID=63042160

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052884A MA52884A (fr) 2018-06-13 2019-06-13 Anticorps anti-il-11

Country Status (25)

Country Link
US (4) US11084874B2 (fr)
EP (1) EP3807314A1 (fr)
JP (2) JP2021535733A (fr)
KR (1) KR20210031690A (fr)
CN (1) CN113056481A (fr)
AU (1) AU2019286795A1 (fr)
BR (1) BR112020025443A2 (fr)
CA (1) CA3102483A1 (fr)
CL (1) CL2020003223A1 (fr)
CO (1) CO2020015383A2 (fr)
CR (1) CR20210009A (fr)
DO (2) DOP2020000245A (fr)
EA (1) EA202092668A1 (fr)
EC (1) ECSP21000695A (fr)
GB (1) GB201809699D0 (fr)
IL (1) IL279356A (fr)
JO (1) JOP20200309A1 (fr)
MA (1) MA52884A (fr)
MX (1) MX2020013583A (fr)
PE (1) PE20211498A1 (fr)
PH (1) PH12020552232A1 (fr)
SA (1) SA520420801B1 (fr)
SG (1) SG11202011782XA (fr)
TW (1) TW202003560A (fr)
WO (1) WO2019238882A1 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
US20180186871A1 (en) 2016-12-16 2018-07-05 Singapore Health Services Pte Ltd. Il-11 antibodies
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
EP3824906A1 (fr) 2016-12-21 2021-05-26 Amgen Inc. Formulations d'anticorps anti-tnf alpha
GB201716733D0 (en) * 2017-10-12 2017-11-29 Nat Univ Singapore Treatment of SMC mediated disease
AU2020211695A1 (en) 2019-01-21 2021-09-02 National University Of Singapore Treatment of hepatotoxicity
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
CN114364693A (zh) 2019-05-03 2022-04-15 新加坡保健服务私人有限公司 代谢性疾病的治疗和预防
GB202009292D0 (en) 2020-06-18 2020-08-05 Singapore Health Serv Pte Ltd Treatment and prevention of disease caused by type IV collagen dysfunction
US20230235029A1 (en) * 2020-07-20 2023-07-27 Integrated Biotherapeutics, Inc. Broadly neutralizing binding molecules against marburgviruses
US20230257458A1 (en) * 2020-08-13 2023-08-17 Sunshine Lake Pharma Co., Ltd. Antibody of il-11 and use thereof
GB202017244D0 (en) 2020-10-30 2020-12-16 Nat Univ Singapore Methods to extend health-span and treat age-related diseases
CN114681592A (zh) * 2020-12-31 2022-07-01 天境生物科技(杭州)有限公司 包含可溶性gp130二聚体的制剂和使用方法
CN113980129B (zh) * 2021-01-15 2023-07-28 东大生物技术(苏州)有限公司 一组il-11单克隆抗体及其医药用途
PE20231503A1 (es) 2021-02-26 2023-09-26 Bayer Ag INHIBIDORES DE IL-11 O IL-11Ra PARA USO EN EL TRATAMIENTO DE SANGRADO UTERINO ANORMAL
US20250092126A1 (en) 2021-07-26 2025-03-20 Boehringer Ingelheim International Gmbh Treatment and prevention of alcoholic liver disease
US20250002574A1 (en) * 2021-08-12 2025-01-02 Sunshine Lake Pharma Co., Ltd. Il-11 humanized antibody and application thereof
US20240425606A1 (en) 2021-08-30 2024-12-26 Lassen Therapeutics 1, Inc. Anti-il-11ra antibodies
EP4448096A1 (fr) 2021-12-16 2024-10-23 Singapore Health Services Pte. Ltd. Traitement et prévention d'une maladie glomérulaire
CN116891528A (zh) * 2022-01-29 2023-10-17 迈威(上海)生物科技股份有限公司 一种抗白介素-11的抗体及其应用
GB202218388D0 (en) 2022-12-07 2023-01-18 Vvb Bio Pte Ltd GP130 antigen-binding molecules
WO2024146458A1 (fr) 2023-01-06 2024-07-11 广东东阳光药业股份有限公司 Anticorps humanisé anti-cytokine il-11
WO2024225979A1 (fr) 2023-04-25 2024-10-31 Vvb Bio Pte Ltd Anticorps anti-il-11
CN120518762A (zh) * 2023-06-05 2025-08-22 北京东方百泰生物科技股份有限公司 一种结合il-11的抗体、其抗原结合片段及应用
GB202311050D0 (en) 2023-07-19 2023-08-30 Vvb Bio Pte Ltd GP130 antigen-binding molecules
CN119424631A (zh) * 2023-07-28 2025-02-14 迈威(上海)生物科技股份有限公司 抗白介素-11抗体在制备肿瘤治疗药物中的应用
WO2025108343A1 (fr) * 2023-11-22 2025-05-30 上海华奥泰生物药业股份有限公司 Protéine de liaison à l'antigène ciblant il-11
WO2025146029A1 (fr) * 2024-01-02 2025-07-10 上海华奥泰生物药业股份有限公司 Molécule multispécifique ciblant il-11 et tslp
GB202405551D0 (en) 2024-04-19 2024-06-05 Vvb Bio Pte Ltd Combination treatment
CN119119262B (zh) * 2024-08-02 2025-05-02 杭州曼迪生物科技有限公司 一种干细胞冻干粉及其在制备药物或者化妆品中的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2399148A1 (fr) * 2000-02-10 2001-08-16 Abbott Laboratories Anticorps de liaison de l'interleukine 18 humaine et procedes de preparation et d'utilisation
US8518888B2 (en) * 2008-10-14 2013-08-27 Csl Limited Method of treatment of gastrointestinal-type cancer with antagonistic antibodies to IL-11R
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
RU2016125115A (ru) * 2016-06-23 2017-12-28 Федеральное государственное бюджетное учреждение науки Институт биологического приборостроения с опытным производством Российской Академии наук (ИБП РАН) Терапевтическое антитело, специфичное к интерлейкину-11, ингибирующее сигналирование через его рецептор, и способ его использования для лечения пациентов
US20180186871A1 (en) * 2016-12-16 2018-07-05 Singapore Health Services Pte Ltd. Il-11 antibodies
RU2016151730A (ru) * 2016-12-28 2018-06-29 Федеральное государственное бюджетное учреждение науки Институт биологического приборостроения с опытным производством Российской Академии наук (ИБП РАН) Антитела для лабораторной диагностики концентрации интерлейкина-11

Also Published As

Publication number Publication date
JP2021535733A (ja) 2021-12-23
IL279356A (en) 2021-01-31
EA202092668A1 (ru) 2021-05-18
MX2020013583A (es) 2021-04-13
JOP20200309A1 (ar) 2020-11-30
US20200031918A1 (en) 2020-01-30
EP3807314A1 (fr) 2021-04-21
KR20210031690A (ko) 2021-03-22
TW202003560A (zh) 2020-01-16
US11084874B2 (en) 2021-08-10
CN113056481A (zh) 2021-06-29
BR112020025443A2 (pt) 2021-03-16
PE20211498A1 (es) 2021-08-11
CL2020003223A1 (es) 2021-07-30
AU2019286795A1 (en) 2021-01-28
CA3102483A1 (fr) 2019-12-19
US20240270837A1 (en) 2024-08-15
WO2019238882A1 (fr) 2019-12-19
DOP2020000245A (es) 2021-10-31
SA520420801B1 (ar) 2023-12-07
DOP2024000220A (es) 2025-02-28
CO2020015383A2 (es) 2021-04-19
JP2024105466A (ja) 2024-08-06
PH12020552232A1 (en) 2021-06-28
CR20210009A (es) 2021-06-21
GB201809699D0 (en) 2018-08-01
SG11202011782XA (en) 2020-12-30
US20210230266A1 (en) 2021-07-29
US20240190953A1 (en) 2024-06-13
ECSP21000695A (es) 2021-03-31

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