MA52884A - Anticorps anti-il-11 - Google Patents

Anticorps anti-il-11

Info

Publication number
MA52884A
MA52884A MA052884A MA52884A MA52884A MA 52884 A MA52884 A MA 52884A MA 052884 A MA052884 A MA 052884A MA 52884 A MA52884 A MA 52884A MA 52884 A MA52884 A MA 52884A
Authority
MA
Morocco
Prior art keywords
antibodies
Prior art date
Application number
MA052884A
Other languages
English (en)
Inventor
Stuart Alexander Cook
Sebastian Schaefer
Original Assignee
Boehringer Ingelheim Int
Nat Univ Singapore
Singapore Health Serv Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Nat Univ Singapore, Singapore Health Serv Pte Ltd filed Critical Boehringer Ingelheim Int
Publication of MA52884A publication Critical patent/MA52884A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • G01N33/575
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
MA052884A 2018-06-13 2019-06-13 Anticorps anti-il-11 MA52884A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1809699.0A GB201809699D0 (en) 2018-06-13 2018-06-13 IL-11 antibodies

Publications (1)

Publication Number Publication Date
MA52884A true MA52884A (fr) 2021-04-21

Family

ID=63042160

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052884A MA52884A (fr) 2018-06-13 2019-06-13 Anticorps anti-il-11

Country Status (25)

Country Link
US (4) US11084874B2 (fr)
EP (1) EP3807314A1 (fr)
JP (2) JP2021535733A (fr)
KR (1) KR20210031690A (fr)
CN (1) CN113056481A (fr)
AU (1) AU2019286795A1 (fr)
BR (1) BR112020025443A2 (fr)
CA (1) CA3102483A1 (fr)
CL (1) CL2020003223A1 (fr)
CO (1) CO2020015383A2 (fr)
CR (1) CR20210009A (fr)
DO (2) DOP2020000245A (fr)
EA (1) EA202092668A1 (fr)
EC (1) ECSP21000695A (fr)
GB (1) GB201809699D0 (fr)
IL (1) IL279356A (fr)
JO (1) JOP20200309A1 (fr)
MA (1) MA52884A (fr)
MX (1) MX2020013583A (fr)
PE (1) PE20211498A1 (fr)
PH (1) PH12020552232A1 (fr)
SA (1) SA520420801B1 (fr)
SG (1) SG11202011782XA (fr)
TW (1) TW202003560A (fr)
WO (1) WO2019238882A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
KR20190096390A (ko) 2016-12-16 2019-08-19 싱가포르 헬스 서비시즈 피티이 엘티디 Il-11 항체
EP3824906A1 (fr) 2016-12-21 2021-05-26 Amgen Inc. Formulations d'anticorps anti-tnf alpha
GB201716733D0 (en) * 2017-10-12 2017-11-29 Nat Univ Singapore Treatment of SMC mediated disease
AU2020211695A1 (en) * 2019-01-21 2021-09-02 National University Of Singapore Treatment of hepatotoxicity
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
CA3146344A1 (fr) 2019-05-03 2020-11-12 Singapore Health Services Pte. Ltd. Traitement et prevention de maladies metaboliques
GB202009292D0 (en) 2020-06-18 2020-08-05 Singapore Health Serv Pte Ltd Treatment and prevention of disease caused by type IV collagen dysfunction
EP4181959A4 (fr) * 2020-07-20 2024-11-06 Razi Holdings, Inc. Molécules de liaison à large spectre de neutralisation contre les virus de marbourg
JP2023537422A (ja) * 2020-08-13 2023-08-31 サンシャイン・レイク・ファーマ・カンパニー・リミテッド Il-11の抗体及びその使用
GB202017244D0 (en) 2020-10-30 2020-12-16 Nat Univ Singapore Methods to extend health-span and treat age-related diseases
CN114681592A (zh) * 2020-12-31 2022-07-01 天境生物科技(杭州)有限公司 包含可溶性gp130二聚体的制剂和使用方法
CN113980129B (zh) * 2021-01-15 2023-07-28 东大生物技术(苏州)有限公司 一组il-11单克隆抗体及其医药用途
WO2022180172A1 (fr) 2021-02-26 2022-09-01 Bayer Aktiengesellschaft Inhibiteurs de l'il-11 ou de l'il-11ra destinés à être utilisés dans le traitement d'un saignement utérin anormal
US20250092126A1 (en) 2021-07-26 2025-03-20 Boehringer Ingelheim International Gmbh Treatment and prevention of alcoholic liver disease
WO2023016505A1 (fr) * 2021-08-12 2023-02-16 广东东阳光药业有限公司 Anticorps humanisé anti-il-11 et son utilisation
KR20240067079A (ko) 2021-08-30 2024-05-16 라센 테라퓨틱스 1, 인코포레이티드 항-IL-11Rα 항체
EP4448096A1 (fr) 2021-12-16 2024-10-23 Singapore Health Services Pte. Ltd. Traitement et prévention d'une maladie glomérulaire
KR20240139077A (ko) * 2022-01-29 2024-09-20 맵웰 (상하이) 바이오사이언스 컴퍼니, 리미티드 항-인터루킨-11 항체 및 이의 용도
GB202218388D0 (en) 2022-12-07 2023-01-18 Vvb Bio Pte Ltd GP130 antigen-binding molecules
CN118307670A (zh) 2023-01-06 2024-07-09 广东东阳光药业股份有限公司 抗il-11细胞因子人源化抗体
WO2024225979A1 (fr) 2023-04-25 2024-10-31 Vvb Bio Pte Ltd Anticorps anti-il-11
CN119080927B (zh) * 2023-06-05 2025-06-24 北京东方百泰生物科技股份有限公司 一种结合il-11的抗体、其抗原结合片段及应用
GB202311050D0 (en) 2023-07-19 2023-08-30 Vvb Bio Pte Ltd GP130 antigen-binding molecules
WO2025026206A1 (fr) * 2023-07-28 2025-02-06 迈威(上海)生物科技股份有限公司 Utilisation d'anticorps anti-interleukine-11 dans la préparation d'un médicament pour le traitement de tumeurs
WO2025108343A1 (fr) * 2023-11-22 2025-05-30 上海华奥泰生物药业股份有限公司 Protéine de liaison à l'antigène ciblant il-11
TW202528345A (zh) * 2024-01-02 2025-07-16 大陸商上海華奧泰生物藥業股份有限公司 靶向il-11和tslp的多特異性分子
GB202405551D0 (en) 2024-04-19 2024-06-05 Vvb Bio Pte Ltd Combination treatment
GB202408044D0 (en) 2024-06-06 2024-07-24 Vvb Bio Pte Ltd gp130 antigen-binding molecules
WO2026001793A1 (fr) * 2024-06-27 2026-01-02 上海华奥泰生物药业股份有限公司 Protéine de liaison à l'antigène ciblant il-11 et son utilisation
CN119119262B (zh) * 2024-08-02 2025-05-02 杭州曼迪生物科技有限公司 一种干细胞冻干粉及其在制备药物或者化妆品中的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1257585A2 (fr) * 2000-02-10 2002-11-20 Basf Aktiengesellschaft Anticorps de liaison de l'interleukine 18 humaine et procedes de preparation et d'utilisation
US8518888B2 (en) * 2008-10-14 2013-08-27 Csl Limited Method of treatment of gastrointestinal-type cancer with antagonistic antibodies to IL-11R
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
RU2016125115A (ru) * 2016-06-23 2017-12-28 Федеральное государственное бюджетное учреждение науки Институт биологического приборостроения с опытным производством Российской Академии наук (ИБП РАН) Терапевтическое антитело, специфичное к интерлейкину-11, ингибирующее сигналирование через его рецептор, и способ его использования для лечения пациентов
KR20190096390A (ko) * 2016-12-16 2019-08-19 싱가포르 헬스 서비시즈 피티이 엘티디 Il-11 항체
RU2016151730A (ru) * 2016-12-28 2018-06-29 Федеральное государственное бюджетное учреждение науки Институт биологического приборостроения с опытным производством Российской Академии наук (ИБП РАН) Антитела для лабораторной диагностики концентрации интерлейкина-11

Also Published As

Publication number Publication date
JP2024105466A (ja) 2024-08-06
US20200031918A1 (en) 2020-01-30
JP2021535733A (ja) 2021-12-23
BR112020025443A2 (pt) 2021-03-16
MX2020013583A (es) 2021-04-13
CL2020003223A1 (es) 2021-07-30
JOP20200309A1 (ar) 2020-11-30
CN113056481A (zh) 2021-06-29
KR20210031690A (ko) 2021-03-22
US11084874B2 (en) 2021-08-10
SG11202011782XA (en) 2020-12-30
SA520420801B1 (ar) 2023-12-07
ECSP21000695A (es) 2021-03-31
CR20210009A (es) 2021-06-21
PH12020552232A1 (en) 2021-06-28
CA3102483A1 (fr) 2019-12-19
AU2019286795A1 (en) 2021-01-28
CO2020015383A2 (es) 2021-04-19
IL279356A (en) 2021-01-31
US20240190953A1 (en) 2024-06-13
EA202092668A1 (ru) 2021-05-18
GB201809699D0 (en) 2018-08-01
US20240270837A1 (en) 2024-08-15
DOP2020000245A (es) 2021-10-31
PE20211498A1 (es) 2021-08-11
EP3807314A1 (fr) 2021-04-21
TW202003560A (zh) 2020-01-16
DOP2024000220A (es) 2025-02-28
WO2019238882A1 (fr) 2019-12-19
US20210230266A1 (en) 2021-07-29

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