|
US20040009166A1
(en)
*
|
1997-04-30 |
2004-01-15 |
Filpula David R. |
Single chain antigen-binding polypeptides for polymer conjugation
|
|
CA2288992C
(en)
*
|
1997-04-30 |
2012-06-12 |
Enzon, Inc. |
Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof
|
|
US6333396B1
(en)
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
|
AU768295B2
(en)
*
|
1998-11-03 |
2003-12-04 |
Centocor Inc. |
Modified antibodies and antibody fragments with increased duration of activity
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
US7122632B2
(en)
|
1999-12-23 |
2006-10-17 |
Zymogenetics, Inc. |
Soluble Interleukin-20 receptor
|
|
MXPA02006795A
(es)
|
2000-01-10 |
2005-04-19 |
Maxygen Holdings Ltd |
Conjugados g-csf.
|
|
IL150692A0
(en)
|
2000-02-11 |
2003-02-12 |
Maxygen Aps |
FACTOR VII OR VIIa-LIKE MOLECULES
|
|
US20030027207A1
(en)
*
|
2000-02-29 |
2003-02-06 |
Filpula David Ray |
Anti-platelet binding proteins and polymer conjugates containing the same
|
|
US6410246B1
(en)
*
|
2000-06-23 |
2002-06-25 |
Genetastix Corporation |
Highly diverse library of yeast expression vectors
|
|
US6410271B1
(en)
*
|
2000-06-23 |
2002-06-25 |
Genetastix Corporation |
Generation of highly diverse library of expression vectors via homologous recombination in yeast
|
|
CA2412279A1
(en)
*
|
2000-09-08 |
2002-03-14 |
Gryphon Therapeutics, Inc. |
"pseudo"-native chemical ligation
|
|
US7118737B2
(en)
*
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
|
US8110218B2
(en)
*
|
2000-11-30 |
2012-02-07 |
The Research Foundation Of State University Of New York |
Compositions and methods for less immunogenic protein-lipid complexes
|
|
AU2002223350A1
(en)
*
|
2000-12-01 |
2002-06-11 |
Eleanor N. Fish |
Cytokine receptor binding peptides
|
|
US6979556B2
(en)
|
2000-12-14 |
2005-12-27 |
Genentech, Inc. |
Separate-cistron contructs for secretion of aglycosylated antibodies from prokaryotes
|
|
US7195923B2
(en)
*
|
2001-01-31 |
2007-03-27 |
Scripps Laboratories, Inc. |
Ratiometric determination of glycated protein
|
|
CA2469846A1
(en)
|
2001-02-27 |
2002-09-26 |
Maxygen Aps |
New interferon beta-like molecules
|
|
KR100968664B1
(ko)
|
2001-08-27 |
2010-07-06 |
제넨테크, 인크. |
항체 발현 및 조립을 위한 시스템
|
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
US7157277B2
(en)
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
|
US8008252B2
(en)
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
|
CA2746308A1
(en)
|
2001-12-17 |
2003-06-26 |
Zymogenetics, Inc. |
Method for treating human papilloma virus
|
|
WO2003062278A1
(en)
|
2002-01-25 |
2003-07-31 |
G2 Therapies Ltd |
MONOCLONAL ANTIBODIES AGAINST EXTRACELLULAR LOOPS OF C5aR
|
|
RU2362807C2
(ru)
|
2002-06-21 |
2009-07-27 |
Ново Нордиск Хелт Кэр Аг |
Конъюгат полипептида фактора vii, способ его получения, его применение и содержащая его фармацевтическая композиция
|
|
MXPA04012496A
(es)
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
US20050026866A1
(en)
*
|
2002-08-02 |
2005-02-03 |
Pawelek John M. |
Agents and methods for treatment of disease by oligosaccharide targeting agents
|
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
|
US7759055B2
(en)
*
|
2002-08-28 |
2010-07-20 |
Millipore Corporation |
Compositions of solution for sequencing reaction clean-up
|
|
US8129330B2
(en)
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
US20040062748A1
(en)
*
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
EP1616003A4
(en)
|
2002-12-30 |
2007-06-20 |
Gryphon Therapeutics Inc |
WATER-SOLUBLE THIOESTER AND SELENOESTER COMPOUNDS AND METHOD FOR THE PRODUCTION AND USE THEREOF
|
|
WO2004071420A2
(en)
*
|
2003-02-05 |
2004-08-26 |
The Research Foundation Of State University Of New York |
Compositions and methods for less immunogenic protein formulations
|
|
US7351688B2
(en)
*
|
2003-02-05 |
2008-04-01 |
The Research Foundation Of State University Of New York |
Compositions and methods for less immunogenic protein formulations
|
|
ES2420581T3
(es)
|
2003-03-14 |
2013-08-26 |
Biogenerix Gmbh |
Polímeros solubles en agua ramificados y sus conjugados
|
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
|
SG155777A1
(en)
|
2003-04-09 |
2009-10-29 |
Neose Technologies Inc |
Glycopegylation methods and proteins/peptides produced by the methods
|
|
ES2380093T3
(es)
*
|
2003-05-09 |
2012-05-08 |
Biogenerix Ag |
Composiciones y métodos para la preparación de mutantes de glucosilación de la hormona del crecimiento humana
|
|
CA2529819A1
(en)
*
|
2003-06-30 |
2004-09-23 |
Domantis Limited |
Pegylated single domain antibodies
|
|
US9005625B2
(en)
*
|
2003-07-25 |
2015-04-14 |
Novo Nordisk A/S |
Antibody toxin conjugates
|
|
US20050069578A1
(en)
*
|
2003-08-05 |
2005-03-31 |
Balasubramanian Sathyamangalam V. |
Reconstitution medium for protein and peptide formulations
|
|
US20050055024A1
(en)
*
|
2003-09-08 |
2005-03-10 |
James Anthony H. |
Orthopaedic implant and screw assembly
|
|
CA2542179A1
(en)
|
2003-10-10 |
2005-04-21 |
Novo Nordisk A/S |
Il-21 derivatives
|
|
EP2633866A3
(en)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Combination therapy
|
|
WO2005052001A2
(en)
*
|
2003-11-21 |
2005-06-09 |
Zymogenetics, Inc. |
Anti-il-20 receptor antibodies and binding partners and methods of using in inflammation
|
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
|
US7956032B2
(en)
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
|
US20060040856A1
(en)
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
|
US20080220049A1
(en)
*
|
2003-12-05 |
2008-09-11 |
Adnexus, A Bristol-Myers Squibb R&D Company |
Compositions and methods for intraocular delivery of fibronectin scaffold domain proteins
|
|
JP5006651B2
(ja)
|
2003-12-05 |
2012-08-22 |
ブリストル−マイヤーズ スクウィブ カンパニー |
２型血管内皮増殖因子受容体の阻害剤
|
|
WO2005070138A2
(en)
|
2004-01-08 |
2005-08-04 |
Neose Technologies, Inc. |
O-linked glycosylation of peptides
|
|
MXPA06008507A
(es)
|
2004-02-02 |
2008-02-13 |
Ambrx Inc |
Cuatro polipeptidos en haz helicoidal humanos modificados y sus usos.
|
|
CN102532321B
(zh)
|
2004-06-18 |
2018-10-12 |
Ambrx公司 |
新颖抗原结合多肽和其用途
|
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
|
US20090292110A1
(en)
*
|
2004-07-23 |
2009-11-26 |
Defrees Shawn |
Enzymatic modification of glycopeptides
|
|
US20060045866A1
(en)
*
|
2004-09-01 |
2006-03-02 |
Chris Chappelow |
Novel high purity and high molecular weight mPEG alcohol compositions
|
|
WO2006031811A2
(en)
|
2004-09-10 |
2006-03-23 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
|
EP2586456B1
(en)
|
2004-10-29 |
2016-01-20 |
ratiopharm GmbH |
Remodeling and glycopegylation of fibroblast growth factor (FGF)
|
|
CN103690936A
(zh)
|
2004-12-22 |
2014-04-02 |
Ambrx公司 |
经修饰的人类生长激素
|
|
MX2007007581A
(es)
|
2004-12-22 |
2007-07-24 |
Ambrx Inc |
Composiciones de amino acil-arnt sintetasa y sus usos.
|
|
WO2006071840A2
(en)
|
2004-12-22 |
2006-07-06 |
Ambrx, Inc. |
Formulations of human growth hormone comprising a non-naturally encoded amino acid
|
|
AU2005323106B2
(en)
|
2004-12-22 |
2010-07-29 |
Ambrx, Inc. |
Methods for expression and purification of recombinant human growth hormone
|
|
JP4951527B2
(ja)
|
2005-01-10 |
2012-06-13 |
バイオジェネリックス アーゲー |
糖ｐｅｇ化顆粒球コロニー刺激因子
|
|
CA2595695A1
(en)
*
|
2005-01-25 |
2006-08-03 |
Cell Therapeutics, Inc. |
Biologically active protein conjugates comprising (nn[s/t]) peptide repeats and having increased plasma half-life
|
|
WO2006097682A1
(en)
*
|
2005-03-18 |
2006-09-21 |
Ucl Business Plc |
Mechano growth factor peptides and their use
|
|
WO2006102659A2
(en)
*
|
2005-03-23 |
2006-09-28 |
Nektar Therapeutics Al, Corporation |
CONJUGATES OF AN hGH MOIETY AND A POLYMER
|
|
WO2006105993A2
(en)
|
2005-04-05 |
2006-10-12 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Method for shielding functional sites or epitopes on proteins
|
|
US20070154992A1
(en)
|
2005-04-08 |
2007-07-05 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
|
US20080255026A1
(en)
|
2005-05-25 |
2008-10-16 |
Glycopegylated Factor 1X |
Glycopegylated Factor Ix
|
|
US20110003744A1
(en)
*
|
2005-05-25 |
2011-01-06 |
Novo Nordisk A/S |
Glycopegylated Erythropoietin Formulations
|
|
EP1888098A2
(en)
|
2005-05-25 |
2008-02-20 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin formulations
|
|
WO2006133088A2
(en)
|
2005-06-03 |
2006-12-14 |
Ambrx, Inc. |
Improved human interferon molecules and their uses
|
|
US8028453B2
(en)
*
|
2005-06-16 |
2011-10-04 |
Hold That Thought, Inc. |
Apparatus and methods for displaying a card
|
|
WO2006134173A2
(en)
|
2005-06-17 |
2006-12-21 |
Novo Nordisk Health Care Ag |
Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
|
|
US7695710B2
(en)
*
|
2005-06-20 |
2010-04-13 |
Pepgen Corporation |
Antitumor and antiviral combination therapies using low-toxicity, long-circulating human interferon-alpha analogs
|
|
KR20080037656A
(ko)
*
|
2005-06-20 |
2008-04-30 |
펩젠 코포레이션 |
저독성의 장시간 순환하는 사람 인터페론-알파 유사체 및인터페론 타우의 키메라
|
|
BRPI0612843A2
(pt)
*
|
2005-06-29 |
2010-11-30 |
Univ New York State Res Found |
composição farmacêutica, métodos para fabricar a composição, e, uso de uma formulação
|
|
WO2007021822A2
(en)
*
|
2005-08-09 |
2007-02-22 |
The Research Foundation Of State Of University Of New York At Buffalo |
Compositions and methods of preparation of liposomal microparticulate il-12
|
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
|
WO2007026972A2
(en)
*
|
2005-09-01 |
2007-03-08 |
Canon Kabushiki Kaisha |
Binding protein molecule
|
|
US8168592B2
(en)
|
2005-10-21 |
2012-05-01 |
Amgen Inc. |
CGRP peptide antagonists and conjugates
|
|
US20090048440A1
(en)
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
|
ES2547554T3
(es)
|
2005-11-16 |
2015-10-07 |
Ambrx, Inc. |
Métodos y composiciones que comprenden aminoácidos no naturales
|
|
US7875288B2
(en)
*
|
2006-03-30 |
2011-01-25 |
The Research Foundation Of State University Of New York |
Method for treating blood coagulation disorders
|
|
CA2660310C
(en)
*
|
2006-03-30 |
2015-04-21 |
The Research Foundation Of State University Of New York |
Compositions of less immunogenic and long-circulating protein-lipid complexes
|
|
US7645860B2
(en)
*
|
2006-03-31 |
2010-01-12 |
Baxter Healthcare S.A. |
Factor VIII polymer conjugates
|
|
US7985839B2
(en)
*
|
2006-03-31 |
2011-07-26 |
Baxter International Inc. |
Factor VIII polymer conjugates
|
|
US7982010B2
(en)
*
|
2006-03-31 |
2011-07-19 |
Baxter International Inc. |
Factor VIII polymer conjugates
|
|
BRPI0708832A2
(pt)
|
2006-03-31 |
2011-06-14 |
Baxter Int |
construÇço proteinÁcea
|
|
JP2009533347A
(ja)
|
2006-04-07 |
2009-09-17 |
ネクター セラピューティックス エイエル，コーポレイション |
抗ＴＮＦα抗体の複合体
|
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
|
EP2018437A2
(en)
|
2006-05-02 |
2009-01-28 |
Allozyne, Inc. |
Non-natural amino acid substituted polypeptides
|
|
KR20090013816A
(ko)
|
2006-05-24 |
2009-02-05 |
노보 노르디스크 헬스 케어 악티엔게젤샤프트 |
연장된 생체내 반감기를 갖는 인자 ⅸ 유사체
|
|
DK2426150T3
(en)
|
2006-06-30 |
2018-01-22 |
Novo Nordisk As |
ANTI-NKG2A ANTIBODIES AND APPLICATIONS THEREOF
|
|
JP2009544327A
(ja)
|
2006-07-21 |
2009-12-17 |
ノヴォ ノルディスク アー／エス |
Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
|
|
CN106008699A
(zh)
|
2006-09-08 |
2016-10-12 |
Ambrx公司 |
经修饰的人类血浆多肽或Fc骨架和其用途
|
|
PT2061878E
(pt)
|
2006-09-08 |
2014-04-22 |
Ambrx Inc |
Supressor híbrido arnt para células de vertebrados
|
|
JP2008069073A
(ja)
*
|
2006-09-12 |
2008-03-27 |
Yokohama Tlo Co Ltd |
ラクトフェリン複合体及びその製造方法
|
|
US8367065B2
(en)
*
|
2006-09-15 |
2013-02-05 |
Enzon Pharmaceuticals, Inc. |
Targeted polymeric prodrugs containing multifunctional linkers
|
|
CA2662981A1
(en)
*
|
2006-09-15 |
2008-03-20 |
Enzon Pharmaceuticals, Inc. |
Targeted polymeric prodrugs containing multifunctional linkers
|
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
EP2054521A4
(en)
|
2006-10-03 |
2012-12-19 |
Novo Nordisk As |
METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
|
|
KR20090110295A
(ko)
*
|
2006-11-22 |
2009-10-21 |
에드넥서스, 어 브리스톨-마이어스 스퀴브 알＆디 컴파니 |
Ｉｇｆ-ｉｒ을 포함하는 티로신 키나제 수용체에 대한 공학처리된 단백질에 기반한 표적화 치료제
|
|
EP2101821B1
(en)
|
2006-12-15 |
2014-08-13 |
Baxter International Inc. |
Factor viia- (poly) sialic acid conjugate having prolonged in vivo half-life
|
|
KR20170037677A
(ko)
*
|
2007-01-30 |
2017-04-04 |
에피백스, 인크. |
조절 ｔ 세포 에피토프, 그의 조성물 및 용도
|
|
EP2111228B1
(en)
*
|
2007-02-02 |
2011-07-20 |
Bristol-Myers Squibb Company |
10Fn3 domain for use in treating diseases associated with inappropriate angiogenesis
|
|
ES2385114T3
(es)
|
2007-03-30 |
2012-07-18 |
Ambrx, Inc. |
Polipéptidos de FGF-21 modificados y sus usos
|
|
NZ580030A
(en)
|
2007-04-03 |
2012-06-29 |
Biogenerix Ag |
Methods of treatment using glycopegylated g-csf
|
|
BRPI0810622A2
(pt)
|
2007-05-02 |
2020-10-13 |
Ambrx, Inc. |
polipeptídeos de interferon beta modificados e seus usos
|
|
JP5876649B2
(ja)
|
2007-06-12 |
2016-03-02 |
ラツィオファルム ゲーエムベーハーｒａｔｉｏｐｈａｒｍ ＧｍｂＨ |
ヌクレオチド糖の改良製造法
|
|
US7968811B2
(en)
*
|
2007-06-29 |
2011-06-28 |
Harley-Davidson Motor Company Group, Inc. |
Integrated ignition and key switch
|
|
CN101848733A
(zh)
*
|
2007-07-13 |
2010-09-29 |
艾博特生物技术有限公司 |
用于肺部给予TNFα抑制剂的方法和组合物
|
|
CA2707840A1
(en)
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
|
CA2697032C
(en)
|
2007-08-22 |
2021-09-14 |
The Regents Of The University Of California |
Activatable binding polypeptides and methods of identification and use thereof
|
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
JP5933894B2
(ja)
|
2007-09-14 |
2016-06-15 |
アディマブ， エルエルシー |
合理的に設計された、合成抗体ライブラリおよびその使用
|
|
ES2369230T3
(es)
*
|
2007-11-15 |
2011-11-28 |
Nestec S.A. |
Producción de productos alimenticios con frescura en boca y mental, mejorada.
|
|
CN101918026B
(zh)
|
2007-11-20 |
2016-03-02 |
Ambrx公司 |
经修饰胰岛素多肽和其用途
|
|
WO2009078970A1
(en)
|
2007-12-14 |
2009-06-25 |
Biotium, Inc. |
Fluorescent compounds
|
|
JP5591712B2
(ja)
|
2007-12-14 |
2014-09-17 |
ノボ・ノルデイスク・エー／エス |
ヒトｎｋｇ２ｄに対する抗体とその使用
|
|
KR20100110864A
(ko)
|
2008-01-24 |
2010-10-13 |
노보 노르디스크 에이/에스 |
인간화된 항-인간 ｎｋｇ2ａ 모노클로날 항체
|
|
MX344166B
(es)
|
2008-02-08 |
2016-12-07 |
Ambrx Inc |
Leptina-polipeptidos modificados y sus usos.
|
|
AU2009213141A1
(en)
|
2008-02-14 |
2009-08-20 |
Bristol-Myers Squibb Company |
Targeted therapeutics based on engineered proteins that bind EGFR
|
|
RU2010138612A
(ru)
|
2008-02-20 |
2012-03-27 |
Джи2 ИНФЛЕММЕЙШН ПТИ ЛТД (AU) |
ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ C5аR
|
|
EP2626080A3
(en)
|
2008-02-27 |
2014-03-05 |
Novo Nordisk A/S |
Conjugated factor VIII molecules
|
|
AR071874A1
(es)
|
2008-05-22 |
2010-07-21 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
|
EP2318029B1
(en)
|
2008-07-23 |
2017-11-01 |
Ambrx, Inc. |
Modified bovine g-csf polypeptides and their uses
|
|
MX343802B
(es)
|
2008-09-26 |
2016-11-23 |
Ambrx Inc |
Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales.
|
|
JP5694171B2
(ja)
|
2008-09-26 |
2015-04-01 |
アンブルックス, インコーポレイテッドAmbrx, Inc. |
修飾されている動物のエリスロポエチンポリペプチドおよびそれらの使用
|
|
WO2010059315A1
(en)
|
2008-11-18 |
2010-05-27 |
Merrimack Pharmaceuticals, Inc. |
Human serum albumin linkers and conjugates thereof
|
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
|
|
AU2009331570C1
(en)
|
2008-12-22 |
2024-04-18 |
Novo Nordisk A/S |
Antibodies against tissue factor pathway inhibitor
|
|
CN106995495A
(zh)
|
2009-01-12 |
2017-08-01 |
希托马克斯医疗有限责任公司 |
修饰抗体组合物及其制备和使用方法
|
|
US9181341B2
(en)
|
2009-01-19 |
2015-11-10 |
Innate Pharma |
Anti-KIR3D antibodies
|
|
BRPI1011384A2
(pt)
|
2009-02-23 |
2016-03-15 |
Cytomx Therapeutics Inc |
pro-proteinas e seus metodos de uso
|
|
US8067201B2
(en)
*
|
2009-04-17 |
2011-11-29 |
Bristol-Myers Squibb Company |
Methods for protein refolding
|
|
CA2766009A1
(en)
*
|
2009-06-25 |
2010-12-29 |
Danisco A/S |
Variant lipolytic enzymes with improved expression, functionality and/or activity
|
|
EA022788B1
(ru)
|
2009-07-03 |
2016-03-31 |
Бионор Иммуно Ас |
Новые терапевтические и диагностические средства
|
|
ES2856055T3
(es)
|
2009-07-27 |
2021-09-27 |
Baxalta GmbH |
Glicopolisialilación de proteínas diferentes de las proteínas de coagulación de la sangre
|
|
KR101912335B1
(ko)
|
2009-07-27 |
2018-10-26 |
리폭센 테크놀로지즈 리미티드 |
비혈액 응고 단백질의 글리코폴리시알화
|
|
DK2459224T3
(en)
*
|
2009-07-27 |
2016-07-25 |
Baxalta GmbH |
Blodstørkningsproteinkonjugater
|
|
US8642737B2
(en)
|
2010-07-26 |
2014-02-04 |
Baxter International Inc. |
Nucleophilic catalysts for oxime linkage
|
|
US8809501B2
(en)
|
2009-07-27 |
2014-08-19 |
Baxter International Inc. |
Nucleophilic catalysts for oxime linkage
|
|
WO2011030107A1
(en)
|
2009-09-10 |
2011-03-17 |
Ucb Pharma S.A. |
Multivalent antibodies
|
|
US8658434B2
(en)
*
|
2009-10-28 |
2014-02-25 |
Biotium, Inc. |
Fluorescent pyrene compounds
|
|
GB0920127D0
(en)
*
|
2009-11-17 |
2009-12-30 |
Ucb Pharma Sa |
Antibodies
|
|
BR112012015597A2
(pt)
|
2009-12-21 |
2017-01-31 |
Ambrx Inc |
peptídeos de somatotropina suínos modificados e seus usos
|
|
CA2784793A1
(en)
|
2009-12-21 |
2011-07-21 |
Ambrx, Inc. |
Modified bovine somatotropin polypeptides and their uses
|
|
TWI513466B
(zh)
|
2010-01-20 |
2015-12-21 |
Boehringer Ingelheim Int |
抗凝血劑解毒劑
|
|
US10080799B2
(en)
|
2010-02-12 |
2018-09-25 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Methods and compositions related to glycoprotein-immunoglobulin fusions
|
|
RU2012139181A
(ru)
|
2010-02-26 |
2014-04-10 |
Ново Нордиск А/С |
Стабильная композиция, содержащая антитело
|
|
EP2542569B1
(en)
|
2010-03-05 |
2020-09-16 |
Omeros Corporation |
Chimeric inhibitor molecules of complement activation
|
|
TW201138808A
(en)
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
JP2013528374A
(ja)
|
2010-05-10 |
2013-07-11 |
パーシード セラピューティクス リミテッド ライアビリティ カンパニー |
Ｖｌａ４のポリペプチド阻害剤
|
|
EP2576615B1
(en)
|
2010-05-26 |
2016-03-30 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins having improved stability
|
|
WO2011147921A1
(en)
|
2010-05-28 |
2011-12-01 |
Novo Nordisk A/S |
Stable multi-dose compositions comprising an antibody and a preservative
|
|
US9127052B2
(en)
|
2010-06-29 |
2015-09-08 |
Centre National De La Recherche Scientifique |
LLT-1 antibodies with new functional properties
|
|
TW201212938A
(en)
|
2010-06-30 |
2012-04-01 |
Novo Nordisk As |
Antibodies that are capable of specifically binding tissue factor pathway inhibitor
|
|
JP6266343B2
(ja)
|
2010-07-16 |
2018-01-24 |
アディマブ， エルエルシー |
抗体ライブラリー
|
|
EA030886B1
(ru)
|
2010-08-17 |
2018-10-31 |
Амбркс, Инк. |
Модифицированные полипептиды релаксина, содержащие некодируемую в природе аминокислоту, связанную с полимером, и их применение
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
|
KR102025442B1
(ko)
|
2010-12-22 |
2019-09-25 |
박스알타 인코퍼레이티드 |
단백질에 수용성 지방산 유도체를 접합하기 위한 물질 및 방법
|
|
JP2014515740A
(ja)
|
2011-03-30 |
2014-07-03 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
抗凝固薬の解毒剤
|
|
CN103619877B
(zh)
|
2011-04-21 |
2018-01-02 |
加文医学研究所 |
修饰的可变结构域分子及其产生和使用方法b
|
|
CN103702721A
(zh)
|
2011-05-31 |
2014-04-02 |
诺沃—诺迪斯克有限公司 |
Il-21表位和il-21配体
|
|
PT3424953T
(pt)
|
2011-06-06 |
2020-11-03 |
Novo Nordisk As |
Anticorpos terapêuticos
|
|
BR112013032217B1
(pt)
|
2011-06-17 |
2021-01-19 |
Novo Nordisk A/S |
uso de um anticorpo anti-nkg2a
|
|
KR20140054009A
(ko)
|
2011-07-01 |
2014-05-08 |
바이엘 인텔렉쳐 프로퍼티 게엠베하 |
릴랙신 융합 폴리펩타이드 및 그의 용도
|
|
CN103747807B
(zh)
|
2011-07-05 |
2016-12-07 |
比奥阿赛斯技术有限公司 |
P97‑抗体缀合物和使用方法
|
|
WO2013011059A1
(en)
|
2011-07-18 |
2013-01-24 |
Novo Nordisk A/S |
Antagonist antibodies against oscar
|
|
WO2013011062A2
(en)
|
2011-07-18 |
2013-01-24 |
Novo Nordisk A/S |
Oscar antagonists
|
|
WO2013011063A1
(en)
|
2011-07-18 |
2013-01-24 |
Novo Nordisk A/S |
Antagonistic antibodies against oscar
|
|
WO2013011061A1
(en)
|
2011-07-18 |
2013-01-24 |
Novo Nordisk A/S |
Antagonistic antibodies against oscar
|
|
CA2858806A1
(en)
|
2011-12-23 |
2013-06-27 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
|
US9663568B2
(en)
|
2012-02-15 |
2017-05-30 |
Novo Nordisk A/S |
Antibodies that bind peptidoglycan recognition protein 1
|
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
|
ES2640268T3
(es)
|
2012-02-15 |
2017-11-02 |
Novo Nordisk A/S |
Anticuerpos que se unen a y bloquean un receptor desencadenante expresado en células mieloides 1 (TREM-1)
|
|
EP2858667A1
(en)
|
2012-06-06 |
2015-04-15 |
Bionor Immuno AS |
Hiv vaccine
|
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
|
WO2014004639A1
(en)
|
2012-06-26 |
2014-01-03 |
Sutro Biopharma, Inc. |
Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
|
|
WO2014006230A1
(en)
|
2012-07-06 |
2014-01-09 |
Novo Nordisk A/S |
Il-20 epitopes and il-20 ligands
|
|
EP2872894B1
(en)
|
2012-07-13 |
2019-04-17 |
Innate Pharma |
Screening of conjugated antibodies
|
|
EP2880156B1
(en)
|
2012-07-31 |
2017-08-23 |
biOasis Technologies Inc |
Dephosphorylated lysosomal storage disease proteins and methods of use thereof
|
|
US20150202287A1
(en)
|
2012-08-30 |
2015-07-23 |
Merrimack Pharmaceuticals, Inc. |
Combination therapies comprising anti-erbb3 agents
|
|
SG11201501464TA
(en)
|
2012-08-31 |
2015-03-30 |
Sutro Biopharma Inc |
Modified amino acids comprising an azido group
|
|
WO2014072482A1
(en)
|
2012-11-09 |
2014-05-15 |
Innate Pharma |
Recognition tags for tgase-mediated conjugation
|
|
CN104884056A
(zh)
|
2012-11-12 |
2015-09-02 |
雷德伍德生物科技股份有限公司 |
用于制备缀合物的化合物和方法
|
|
CA2890906A1
(en)
|
2012-11-16 |
2014-05-22 |
The Regents Of The University Of California |
Pictet-spengler ligation for protein chemical modification
|
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
US10077315B2
(en)
|
2013-02-05 |
2018-09-18 |
Engmab Sàrl |
Bispecific antibodies against CD3 and BCMA
|
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
|
AU2014243816B2
(en)
|
2013-03-13 |
2019-01-31 |
Bioasis Technologies Inc. |
Fragments of p97 and uses thereof
|
|
WO2014140240A1
(en)
|
2013-03-15 |
2014-09-18 |
Novo Nordisk A/S |
Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor
|
|
US10611824B2
(en)
|
2013-03-15 |
2020-04-07 |
Innate Pharma |
Solid phase TGase-mediated conjugation of antibodies
|
|
EP2789630A1
(en)
|
2013-04-09 |
2014-10-15 |
EngMab AG |
Bispecific antibodies against CD3e and ROR1
|
|
WO2014202773A1
(en)
|
2013-06-20 |
2014-12-24 |
Innate Pharma |
Enzymatic conjugation of polypeptides
|
|
KR20160042871A
(ko)
|
2013-06-21 |
2016-04-20 |
이나뜨 파르마, 에스.아. |
폴리펩티드의 효소적 콘쥬게이션
|
|
EP3019522B1
(en)
|
2013-07-10 |
2017-12-13 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
|
WO2015007337A1
(en)
|
2013-07-19 |
2015-01-22 |
Bionor Immuno As |
Method for the vaccination against hiv
|
|
US20150093399A1
(en)
|
2013-08-28 |
2015-04-02 |
Bioasis Technologies, Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
|
KR20240034882A
(ko)
|
2013-10-15 |
2024-03-14 |
씨젠 인크. |
개선된 리간드-약물 컨쥬게이트 약물동력학을 위한 peg화된 약물-링커
|
|
WO2015067755A2
(en)
|
2013-11-07 |
2015-05-14 |
Novo Nordisk A/S |
Novel methods and antibodies for treating coagulapathy
|
|
US9493413B2
(en)
|
2013-11-27 |
2016-11-15 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
AU2015222879B2
(en)
|
2014-02-26 |
2019-12-05 |
The Board Of Regents Of The University Of Texas System |
Nitrobenzaldehyde proton release for manipulation of cellular acidosis
|
|
BR122024001145A2
(pt)
|
2014-03-14 |
2024-02-27 |
Novartis Ag |
Molécula de anticorpo isolada capaz de se ligar a lag-3, seu método de produção, composição farmacêutica, ácidos nucleicos, vetor de expressão, método para detecção de lag-3 em uma amostra biológica, e uso das referidas molécula de anticorpo e composição
|
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
EA034886B1
(ru)
|
2014-03-20 |
2020-04-02 |
Бристол-Майерс Сквибб Компани |
Связывающие сывороточный альбумин домены фибронектина iii типа
|
|
JP6702893B2
(ja)
|
2014-06-27 |
2020-06-03 |
イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． |
多重特異的抗原結合タンパク質
|
|
WO2015197593A1
(en)
|
2014-06-27 |
2015-12-30 |
Innate Pharma |
MULTISPECIFIC NKp46 BINDING PROTEINS
|
|
SG11201700250WA
(en)
|
2014-07-17 |
2017-02-27 |
Novo Nordisk As |
Site directed mutagenesis of trem-1 antibodies for decreasing viscosity
|
|
EP3026061A1
(en)
|
2014-11-26 |
2016-06-01 |
Novo Nordisk A/S |
Site directed mutagenesis of trem-1 antibodies for decreasing viscosity.
|
|
EP2975056A1
(en)
|
2014-07-17 |
2016-01-20 |
Novo Nordisk A/S |
Site directed mutagenesis of TREM-1 antibodies for decreasing viscosity
|
|
BR112017001242A2
(pt)
|
2014-07-21 |
2017-12-05 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico a cd33
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
MX2017001011A
(es)
|
2014-07-21 |
2018-05-28 |
Novartis Ag |
Tratamiento de cancer de usando un receptor quimerico de antigeno anti-bcma.
|
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のｍＴＯＲ阻害剤とＣＡＲの組み合わせ
|
|
US20170209492A1
(en)
|
2014-07-31 |
2017-07-27 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
|
BR112017003104A2
(pt)
|
2014-08-19 |
2017-12-05 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico anti-cd123
|
|
CN114621969A
(zh)
|
2014-09-17 |
2022-06-14 |
诺华股份有限公司 |
用于过继免疫疗法的具有嵌合受体的靶向细胞毒性细胞
|
|
ES2850325T3
(es)
|
2014-10-09 |
2021-08-27 |
Engmab Sarl |
Anticuerpos biespecíficos contra CD3epsilon y ROR1
|
|
CR20170143A
(es)
|
2014-10-14 |
2017-06-19 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas
|
|
PE20170950A1
(es)
|
2014-10-24 |
2017-07-13 |
Bristol Myers Squibb Co |
Polipeptidos del factor de crecimiento de fibroblastos 2 (fgf-21) modificados y usos de los mismos
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
US10610504B2
(en)
|
2014-12-23 |
2020-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Alpha-cell re-generation combined with conversion to beta cells
|
|
CN114958764A
(zh)
|
2015-04-08 |
2022-08-30 |
诺华股份有限公司 |
Cd20疗法、cd22疗法和与cd19嵌合抗原受体（car）表达细胞的联合疗法
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
JP6971153B2
(ja)
|
2015-06-23 |
2021-11-24 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
多重特異的ｎｋエンゲイジャータンパク質
|
|
WO2016207273A2
(en)
|
2015-06-23 |
2016-12-29 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
EP3317301B1
(en)
|
2015-07-29 |
2021-04-07 |
Novartis AG |
Combination therapies comprising antibody molecules to lag-3
|
|
PL3331910T3
(pl)
|
2015-08-03 |
2020-05-18 |
Engmab Sàrl |
Przeciwciała monoklonalne przeciwko ludzkiemu antygenowi dojrzewania limfocytów B (BCMA)
|
|
ES2781207T3
(es)
|
2015-09-23 |
2020-08-31 |
Bristol Myers Squibb Co |
Dominios de fibronectina de tipo iii de unión a seroalbúmina con velocidad de disociación rápida
|
|
US11793880B2
(en)
|
2015-12-04 |
2023-10-24 |
Seagen Inc. |
Conjugates of quaternized tubulysin compounds
|
|
MX2018006218A
(es)
|
2015-12-04 |
2018-09-05 |
Seattle Genetics Inc |
Conjugados de compuestos de tubulisina cuaternizada.
|
|
CA3007421A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Combination of c-met inhibitor with antibody molecule to pd-1 and uses thereof
|
|
EP3389712B1
(en)
|
2015-12-17 |
2024-04-10 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
|
ES2847155T3
(es)
|
2016-01-21 |
2021-08-02 |
Novartis Ag |
Moléculas multiespecíficas que fijan como objetivo CLL-1
|
|
SG11201807489PA
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
BR112018069273A2
(pt)
|
2016-03-25 |
2019-01-22 |
Seattle Genetics Inc |
métodos para preparação de um composto e para tratamento de um indivíduo com uma malignidade hematológica, composto, composição, e, intermediário ligante de fármaco ou composto ligante de fármaco
|
|
IL262321B1
(en)
|
2016-04-15 |
2024-05-01 |
Novartis Ag |
Preparations and methods for selective protein expression
|
|
AU2017266298B2
(en)
|
2016-05-18 |
2024-01-04 |
Boehringer Ingelheim International Gmbh |
Anti PD-1 and anti-LAG3 antibodies for cancer treatment
|
|
US10556936B2
(en)
|
2016-05-27 |
2020-02-11 |
Alk Abelló |
Immunogenic proteins and fragments thereof from allergenic mites
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
KR102382895B1
(ko)
|
2016-07-12 |
2022-04-08 |
카이트 파마 인코포레이티드 |
항원 결합 분자 및 그의 사용 방법
|
|
EP3484455A2
(en)
|
2016-07-15 |
2019-05-22 |
Novartis AG |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
KR20190034588A
(ko)
|
2016-07-28 |
2019-04-02 |
노파르티스 아게 |
키메라 항원 수용체 및 pd-1 억제제의 조합 요법
|
|
KR20190036551A
(ko)
|
2016-08-01 |
2019-04-04 |
노파르티스 아게 |
Pro-m2 대식세포 분자의 억제제를 병용하는, 키메라 항원 수용체를 이용한 암의 치료
|
|
MX2019003886A
(es)
|
2016-10-07 |
2019-08-05 |
Novartis Ag |
Receptores de antigenos quimericos para el tratamiento del cancer.
|
|
JP7267914B2
(ja)
|
2016-11-02 |
2023-05-02 |
エンクマフ エスアーエールエル |
Ｂｃｍａ及びｃｄ３に対する二重特異性抗体、及び多発性骨髄腫を治療するために併用して使用される免疫療法薬
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
US11129906B1
(en)
|
2016-12-07 |
2021-09-28 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
EP3360898A1
(en)
|
2017-02-14 |
2018-08-15 |
Boehringer Ingelheim International GmbH |
Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer
|
|
US20190322767A1
(en)
|
2016-12-23 |
2019-10-24 |
Innate Pharma |
Heterodimeric antigen binding proteins
|
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
|
SG11201907209QA
(en)
|
2017-02-08 |
2019-09-27 |
Bristol Myers Squibb Co |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
|
WO2018160731A1
(en)
|
2017-02-28 |
2018-09-07 |
Novartis Ag |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
SG11201908325PA
(en)
|
2017-03-24 |
2019-10-30 |
Seattle Genetics Inc |
Process for the preparation of glucuronide drug-linkers and intermediates thereof
|
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
WO2018201051A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
SG11201912473PA
(en)
|
2017-06-22 |
2020-01-30 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3645037A1
(en)
|
2017-06-27 |
2020-05-06 |
Novartis AG |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
|
EP3652209A2
(en)
|
2017-07-11 |
2020-05-20 |
Compass Therapeutics LLC |
Agonist antibodies that bind human cd137 and uses thereof
|
|
WO2019018730A1
(en)
|
2017-07-20 |
2019-01-24 |
Novartis Ag |
DOSAGE REGIMES FOR ANTI-LAG3 ANTIBODIES AND USES THEREOF
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
RU2020119578A
(ru)
|
2017-11-16 |
2021-12-17 |
Новартис Аг |
Комбинированные терапии
|
|
WO2019100052A2
(en)
|
2017-11-20 |
2019-05-23 |
Compass Therapeutics Llc |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
AU2018371114A1
(en)
|
2017-11-21 |
2020-05-07 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
WO2019133399A1
(en)
|
2017-12-26 |
2019-07-04 |
Becton, Dickinson And Company |
Deep ultraviolet-excitable water-solvated polymeric dyes
|
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
|
WO2019191482A1
(en)
|
2018-03-30 |
2019-10-03 |
Becton, Dickinson And Company |
Water-soluble polymeric dyes having pendant chromophores
|
|
KR20200139219A
(ko)
|
2018-04-02 |
2020-12-11 |
브리스톨-마이어스 스큅 컴퍼니 |
항-trem-1 항체 및 이의 용도
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
EP3569618A1
(en)
|
2018-05-19 |
2019-11-20 |
Boehringer Ingelheim International GmbH |
Antagonizing cd73 antibody
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
US20200109195A1
(en)
|
2018-05-21 |
2020-04-09 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
|
MA52969A
(fr)
|
2018-06-19 |
2021-04-28 |
Atarga Llc |
Molécules d'anticorps se liant au composant du complément 5 et leurs utilisations
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
US20220162336A1
(en)
|
2018-07-22 |
2022-05-26 |
Bioasis Technologies, Inc. |
Treatment of lymphatic metastases
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
MX2021002575A
(es)
|
2018-09-11 |
2021-06-08 |
Ambrx Inc |
Conjugados de polipeptidos de interleucina-2 y sus usos.
|
|
US20220009986A1
(en)
|
2018-10-19 |
2022-01-13 |
Ambrx, Inc. |
Interleukin-10 polypeptide conjugates, dimers thereof, and their uses
|
|
GB201818477D0
(en)
|
2018-11-13 |
2018-12-26 |
Emstopa Ltd |
Tissue plasminogen activator antibodies and method of use thereof
|
|
JP2022507253A
(ja)
|
2018-11-13 |
2022-01-18 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
チェックポイント分子に対する多重特異性結合性構築物およびその使用
|
|
CA3123356A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Combinations of a hdm2-p53 interaction inhibitor and a bcl2 inhibitor and their use for treating cancer
|
|
EP3897637A1
(en)
|
2018-12-20 |
2021-10-27 |
Novartis AG |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP3923991A1
(en)
|
2019-02-12 |
2021-12-22 |
Ambrx, Inc. |
Compositions containing, methods and uses of antibody-tlr agonist conjugates
|
|
EP3924055B1
(en)
|
2019-02-15 |
2024-04-03 |
Novartis AG |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US20220144807A1
(en)
|
2019-02-15 |
2022-05-12 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
EP3927371A1
(en)
|
2019-02-22 |
2021-12-29 |
Novartis AG |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
SG11202110732XA
(en)
|
2019-03-29 |
2021-10-28 |
Atarga Llc |
Anti fgf23 antibody
|
|
EP3947451A1
(en)
|
2019-04-01 |
2022-02-09 |
Novo Nordisk A/S |
Antibodies directed against liraglutide and use thereof
|
|
JP2022540904A
(ja)
|
2019-07-15 |
2022-09-20 |
ブリストル－マイヤーズ スクイブ カンパニー |
ヒトｔｒｅｍ－１に対する抗体およびその使用
|
|
EP3999543A1
(en)
|
2019-07-15 |
2022-05-25 |
Bristol-Myers Squibb Company |
Anti-trem-1 antibodies and uses thereof
|
|
CA3153311A1
(en)
*
|
2019-09-06 |
2021-03-11 |
The Regents Of The University Of California |
Chimeric antigen receptors and related methods and compositions for the treatment of cancer
|
|
BR112022007376A2
(pt)
|
2019-10-21 |
2022-07-05 |
Novartis Ag |
Terapias de combinação com venetoclax e inibidores de tim-3
|
|
MX2022004769A
(es)
|
2019-10-21 |
2022-05-16 |
Novartis Ag |
Inhibidores de tim-3 y sus usos.
|
|
EP4065158A2
(en)
|
2019-11-26 |
2022-10-05 |
Novartis AG |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
TW202135858A
(zh)
|
2019-12-20 |
2021-10-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體和檢查點抑制劑用於治療增殖性疾病之用途
|
|
CN113186185B
(zh)
*
|
2020-01-14 |
2023-05-26 |
东北林业大学 |
一种从哺乳动物粪便中高效富集宿主dna的方法
|
|
WO2021144657A1
(en)
|
2020-01-17 |
2021-07-22 |
Novartis Ag |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
EP4090762A1
(en)
|
2020-01-17 |
2022-11-23 |
Becton, Dickinson and Company |
Methods and compositions for single cell secretomics
|
|
JP2023515211A
(ja)
|
2020-02-27 |
2023-04-12 |
ノバルティス アーゲー |
キメラ抗原受容体発現細胞を作製する方法
|
|
EP4117732A1
(en)
|
2020-03-11 |
2023-01-18 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and methods of use thereof
|
|
US20210355468A1
(en)
|
2020-05-18 |
2021-11-18 |
Bioasis Technologies, Inc. |
Compositions and methods for treating lewy body dementia
|
|
IL298287A
(en)
|
2020-05-19 |
2023-01-01 |
Boehringer Ingelheim Int |
Binding molecules for cancer treatment
|
|
US20210371503A1
(en)
|
2020-05-29 |
2021-12-02 |
University Of Cologne |
Neutralizing antibodies against sars-related coronavirus
|
|
US20210393787A1
(en)
|
2020-06-17 |
2021-12-23 |
Bioasis Technologies, Inc. |
Compositions and methods for treating frontotemporal dementia
|
|
AU2021297099A1
(en)
|
2020-06-23 |
2023-01-05 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CN116323664A
(zh)
|
2020-07-16 |
2023-06-23 |
诺华股份有限公司 |
抗β细胞素抗体、其片段和多特异性结合分子
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
WO2022029573A1
(en)
|
2020-08-03 |
2022-02-10 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CA3186062A1
(en)
|
2020-08-10 |
2022-02-17 |
Marion BENEZECH |
Cell surface mica and micb detection using antibodies
|
|
JP2023538071A
(ja)
|
2020-08-20 |
2023-09-06 |
アンブルックス，インコーポレイテッド |
抗体－ｔｌｒアゴニストコンジュゲート、その方法及び使用
|
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
TW202233668A
(zh)
|
2020-10-21 |
2022-09-01 |
德商百靈佳殷格翰國際股份有限公司 |
用於治療眼部疾病之雙特異性抗-VEGF及抗-TrkB結合分子
|
|
CA3199319A1
(en)
|
2020-10-22 |
2022-04-28 |
Janssen Biotech, Inc. |
Proteins comprising delta-like ligand 3 (dll3) antigen binding domains and their uses
|
|
CN116472288A
(zh)
|
2020-11-06 |
2023-07-21 |
诺华股份有限公司 |
抗体Fc变体
|
|
WO2022104061A1
(en)
|
2020-11-13 |
2022-05-19 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
WO2022182872A2
(en)
|
2021-02-24 |
2022-09-01 |
Alladapt Immunotherapeutics, Inc. |
Compositions and methods for identification of cross-reactive allergenic proteins and treatment of allergies
|
|
CA3214440A1
(en)
|
2021-03-26 |
2022-09-29 |
Rupesh Nanjunda |
Humanized antibodies against paired helical filament tau and uses thereof
|
|
CA3207652A1
(en)
|
2021-03-26 |
2022-09-29 |
Stephanie Cornen |
Cytokine anchors for nkp46-binding nk cell engager proteins
|
|
AU2022249223A1
(en)
|
2021-04-03 |
2023-10-12 |
Ambrx, Inc. |
Anti-her2 antibody-drug conjugates and uses thereof
|
|
JP2024513880A
(ja)
|
2021-04-05 |
2024-03-27 |
イナート・ファルマ・ソシエテ・アノニム |
免疫組織化学法およびｋｉｒ３ｄｌ２特異的薬剤
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
EP4095156A1
(en)
|
2021-05-28 |
2022-11-30 |
Universität zu Köln |
Neutralizing antibodies against hepatitis c virus
|
|
WO2022258678A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
|
|
KR20240019786A
(ko)
|
2021-06-09 |
2024-02-14 |
이나뜨 파르마 에스.에이. |
Cd20, nkp46, cd16에 결합하고 il-2에 접합된 다중특이적 항체
|
|
WO2022258691A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
|
|
CN117616050A
(zh)
|
2021-06-09 |
2024-02-27 |
先天制药公司 |
与nkp46、细胞因子受体、肿瘤抗原和cd16a结合的多特异性蛋白质
|
|
AR126161A1
(es)
|
2021-06-17 |
2023-09-27 |
Boehringer Lngelheim Int Gmbh |
Moléculas de fijación triespecíficas novedosas
|
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
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|
|
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|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(zh)
|
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|
|
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(zh)
|
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|
|
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(en)
|
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|
|
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(zh)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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Dhnt monomers and polymer dyes with modified photophysical properties
|
|
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(en)
|
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2024-03-21 |
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|
