JP2001510382A - アナライトレベルを測定するための装置及び方法 - Google Patents
アナライトレベルを測定するための装置及び方法Info
- Publication number
- JP2001510382A JP2001510382A JP53868098A JP53868098A JP2001510382A JP 2001510382 A JP2001510382 A JP 2001510382A JP 53868098 A JP53868098 A JP 53868098A JP 53868098 A JP53868098 A JP 53868098A JP 2001510382 A JP2001510382 A JP 2001510382A
- Authority
- JP
- Japan
- Prior art keywords
- glucose
- sensor
- membrane
- body fluid
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
- C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Organic Chemistry (AREA)
- Optics & Photonics (AREA)
- Emergency Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physiology (AREA)
- Computer Networks & Wireless Communication (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. a)電子回路手段、及び該電子回路手段に機能可能なように接続された少な くとも2個の電極を含む外被、及び b)i)生体保護膜、及びii)脈管形成層を含み、前記脈管形成層が外被から 前記生体保護膜よりも遠くに位置している、前記外被の前記電極に機能可能 なように接続されたセンサー手段を含む体液測定装置。 2. 前記生体保護膜が実質的にマクロファージ不透過性である請求項1に記載の 体液測定装置。 3. 前記生体保護膜が孔を含み、該孔が約0.1ミクロン〜約1.0ミクロンの範囲 の直径を有している請求項1に記載の体液測定装置。 4. 前記生体保護膜がポリテトラフルオロエチレンを含む請求項1に記載の体液 測定装置。 5. 前記脈管形成層がポリテトラフルオロエチレンを含む請求項1に記載の体液 測定装置。 6. c)生体組織に前記装置を固定するための手段をさらに含み、該固定手段が 前記外被に係合されている請求項1に記載の体液測定装置。 7. 前記固定手段がポリエチレンテレフタレートを含む請求項6に記載の体液測 定装置。 8. センサー手段が生物学的サンプル中のグルコースの量を測定するための手段 をさらに含む請求項1に記載の体液測定装置。 9. 前記グルコース測定手段がグルコースオキシダーゼを含む膜を含み、前記グ ルコースオキシダーゼを含む膜が、外被から生体保護膜よりも近くに位置す る請求項8に記載の体液測定装置。 10. 前記外被が、装置の外部の位置にデータを伝送するための手段をさらに含 む請求項1に記載の体液測定装置。 11. a)電子回路手段、及び該電子回路手段に機能可能なように接続された少な くとも2個の電極を含む外被、及び b)i)前記電極に機能可能なように接続された、生物学的サンプル中のグル コースの量を測定するための手段、ii)前記外被から前記グルコース測定手 段よりも遠くに位置し、実質的にマクロファージ不透過性である生体保護膜 、及びiii)前記外被から前記生体保護膜よりも遠くに位置している脈管形 成層を含む、前記外被の前記電極に機能可能なように接続されたセンサー手 段を含む、体液中のグルコースを測定するための装置。 12. 前記グルコース測定手段がグルコースオキシダーゼを含む膜を含む請求項 11に記載の体液測定装置。 13. 前記生体保護膜が、約0.1ミクロン〜約1.0ミクロンの範囲の直径を有する 孔をさらに含む請求項11に記載の体液測定装置。 14. 前記生体保護膜の前記孔が約0.2ミクロン〜約0.5ミクロンの範囲の直径を 有する請求項13に記載の体液測定装置。 15. 前記生体保護膜がポリテトラフルオロエチレンを含む請求項11に記載の体 液測定装置。 16. 前記脈管形成層がポリテトラフルオロエチレンを含む請求項11に記載の体 液測定装置。 17. c)生物組織に装置を固定するための手段をさらに含み、該固定手段が前記 外被に係合されている請求項11に記載の体液測定装置。 18. 前記固定手段がポリエチレンテレフタレートを含む請求項17に記載の体液 測定装置。 19. 前記外被が、前記装置の外部の位置にデータを伝送するための手段をさら に含む請求項11に記載の体液測定装置。 20. 前記データ伝送手段が無線通信手段を含む請求項19に記載の体液測定装置 。 21. a)i)宿主、及びii)外被及び体液中のグルコース量を測定するための手 段を含む装置を用意し、 b)前記装置が360日を越える期間にわたってグルコースを正確に測定するよ うな条件下で、前記装置を前記宿主に埋込むことを含む、グルコースレベル をモニターする方法。 22. 前記装置が150日を越える期間について正確にグルコースを測定する請求 項21に記載の方法。 23. 前記装置が90日を越える期間について正確にグルコースを測定する請求項 22に記載の方法。 24. 埋込みが皮下に行われる請求項21に記載の方法。 25. a)i)宿主、及びii)外被、及び正確で連続的なグルコースの検知が可能 な、体液中のグルコース量を測定するための手段を含む装置を用意し、 b)前記連続的なグルコースの検知が2日目頃〜25日目頃に開始されるよう な条件下で、装置を宿主に埋込むことを含む体液中のグルコースを測定する 方法。 26. 前記連続的なグルコースの検知が3日目頃〜21日目頃に開始される請求項 25に記載の方法。 27. 埋込みが皮下に行われる請求項25に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/811,473 | 1997-03-04 | ||
US08/811,473 US6001067A (en) | 1997-03-04 | 1997-03-04 | Device and method for determining analyte levels |
PCT/US1998/004090 WO1998038906A1 (en) | 1997-03-04 | 1998-03-03 | Device and method for determining analyte levels |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2001510382A true JP2001510382A (ja) | 2001-07-31 |
JP2001510382A5 JP2001510382A5 (ja) | 2005-11-10 |
JP4124827B2 JP4124827B2 (ja) | 2008-07-23 |
Family
ID=25206642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53868098A Expired - Fee Related JP4124827B2 (ja) | 1997-03-04 | 1998-03-03 | アナライトレベルを測定するための装置及び方法 |
Country Status (9)
Country | Link |
---|---|
US (10) | US6001067A (ja) |
EP (1) | EP1011425B1 (ja) |
JP (1) | JP4124827B2 (ja) |
AT (1) | ATE361024T1 (ja) |
AU (1) | AU6680098A (ja) |
DE (1) | DE69837709T2 (ja) |
DK (1) | DK1011425T3 (ja) |
ES (1) | ES2286848T3 (ja) |
WO (1) | WO1998038906A1 (ja) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2006500170A (ja) * | 2002-09-27 | 2006-01-05 | メドトロニック ミニメド インコーポレイテッド | 埋込可能型センサ方法及びシステム |
JP2007511737A (ja) * | 2003-07-25 | 2007-05-10 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
JP2007535991A (ja) * | 2004-05-03 | 2007-12-13 | デックスコム・インコーポレーテッド | 植込み可能なアナライトセンサ |
JP2008514255A (ja) * | 2004-09-27 | 2008-05-08 | ズーリ ホルディングズ リミテッド | 埋込み可能なセンサの保護方法及び保護された埋込み可能なセンサ |
JP2008538708A (ja) * | 2005-04-11 | 2008-11-06 | エフ.ホフマン−ラ ロシュ アーゲー | ウェブ対応携帯型医療デバイス |
JP2012213640A (ja) * | 2005-12-28 | 2012-11-08 | Abbott Diabetes Care Inc | 分析物モニタリング |
US8465466B2 (en) | 2001-10-23 | 2013-06-18 | Medtronic Minimed, Inc | Method and system for non-vascular sensor implantation |
US8506550B2 (en) | 2001-09-07 | 2013-08-13 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
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US10219728B2 (en) | 2005-12-28 | 2019-03-05 | Abbott Diabetes Care Inc. | Analyte monitoring: stabilizer for subcutaneous glucose sensor with incorporated antiglycolytic agent |
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JP2007535991A (ja) * | 2004-05-03 | 2007-12-13 | デックスコム・インコーポレーテッド | 植込み可能なアナライトセンサ |
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JP2012213640A (ja) * | 2005-12-28 | 2012-11-08 | Abbott Diabetes Care Inc | 分析物モニタリング |
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US8676288B2 (en) | 2014-03-18 |
EP1011425A4 (en) | 2004-06-16 |
US20100099970A1 (en) | 2010-04-22 |
US9339223B2 (en) | 2016-05-17 |
US7974672B2 (en) | 2011-07-05 |
US20050177036A1 (en) | 2005-08-11 |
US7835777B2 (en) | 2010-11-16 |
US20140128700A1 (en) | 2014-05-08 |
US20110253533A1 (en) | 2011-10-20 |
US20100204555A1 (en) | 2010-08-12 |
DE69837709D1 (de) | 2007-06-14 |
US20100204559A1 (en) | 2010-08-12 |
EP1011425B1 (en) | 2007-05-02 |
ES2286848T3 (es) | 2007-12-01 |
ATE361024T1 (de) | 2007-05-15 |
US7711402B2 (en) | 2010-05-04 |
AU6680098A (en) | 1998-09-22 |
US6001067A (en) | 1999-12-14 |
US8527025B1 (en) | 2013-09-03 |
JP4124827B2 (ja) | 2008-07-23 |
WO1998038906A1 (en) | 1998-09-11 |
DE69837709T2 (de) | 2007-12-06 |
US20140128701A1 (en) | 2014-05-08 |
US7792562B2 (en) | 2010-09-07 |
US7970448B2 (en) | 2011-06-28 |
EP1011425A1 (en) | 2000-06-28 |
DK1011425T3 (da) | 2007-09-10 |
US20100099971A1 (en) | 2010-04-22 |
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