IT1248934B - Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle - Google Patents

Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle

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Publication number
IT1248934B
IT1248934B IT2051390A IT2051390A IT1248934B IT 1248934 B IT1248934 B IT 1248934B IT 2051390 A IT2051390 A IT 2051390A IT 2051390 A IT2051390 A IT 2051390A IT 1248934 B IT1248934 B IT 1248934B
Authority
IT
Italy
Prior art keywords
use
processes
preparation
support
obtained
Prior art date
Application number
IT2051390A
Other languages
English (en)
Other versions
IT9020513A1 (it
IT9020513D0 (it
Inventor
Valle Francesco Della
Gabriella Calderini
Alessandro Rastrelli
Romeo Aurelio
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Priority to IT2051390A priority Critical patent/IT1248934B/it
Publication of IT9020513D0 publication Critical patent/IT9020513D0/it
Publication of IT9020513A1 publication Critical patent/IT9020513A1/it
Application granted granted Critical
Publication of IT1248934B publication Critical patent/IT1248934B/it

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629Keratinocytes; Whole skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/10Hair or skin implants
    • A61F2/105Skin implants, e.g. artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062General methods for three-dimensional culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • C12N2533/80Hyaluronan
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2539/00Supports and/or coatings for cell culture characterised by properties
    • C12N2539/10Coating allowing for selective detachment of cells, e.g. thermoreactive coating
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/24Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24273Structurally defined web or sheet [e.g., overall dimension, etc.] including aperture
IT2051390A 1990-06-01 1990-06-01 Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle IT1248934B (it)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT2051390A IT1248934B (it) 1990-06-01 1990-06-01 Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle

Applications Claiming Priority (26)

Application Number Priority Date Filing Date Title
IT2051390A IT1248934B (it) 1990-06-01 1990-06-01 Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle
IL9825591A IL98255A (en) 1990-06-01 1991-05-24 Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts
DE1991627235 DE69127235T2 (de) 1990-06-01 1991-05-28 Biologisch verträgliche perforierte Membranen und ihre Verwendung als Kunsthaut
EP19910108654 EP0462426B1 (en) 1990-06-01 1991-05-28 Biocompatible perforated membranes and their use as artificial skin
ES91108654T ES2108019T3 (es) 1990-06-01 1991-05-28 Membranas perforadas biocompatibles y su uso como piel artificial.
SG1996005810A SG52545A1 (en) 1990-06-01 1991-05-28 Biocompatible perforated membranes process for their preparation their use as a support in the in vitro growth of epithelial cells the artificial skin
AT91108654T AT156689T (de) 1990-06-01 1991-05-28 Biologisch verträgliche perforierte membranen und ihre verwendung als kunsthaut
IE182591A IE911825A1 (en) 1990-06-01 1991-05-28 Biocompatible perforated membranes, processes for their¹preparation, their use as a support in the in vitro growth¹of epithelial cells, the artificial skin obtained in this¹manner, and its use in skin grafts
DE1991627235 DE69127235D1 (de) 1990-06-01 1991-05-28 Biologisch verträgliche perforierte Membranen und ihre Verwendung als Kunsthaut
DK91108654T DK0462426T3 (da) 1990-06-01 1991-05-28 Biokompatible, perforerede membraner og deres anvendelse som kunstig hud
ZA914098A ZA9104098B (en) 1990-06-01 1991-05-29 Biocompatible perforated membranes,processes for their preparation,their use as a support in the in vitro growth of epithelial cells,the artificial skin obtained in this manner,and its use in skin grafts
BR9102225A BR9102225A (pt) 1990-06-01 1991-05-29 Membranas biocompativeis,processo para sua preparacao e pele artificial
NO912058A NO303562B1 (no) 1990-06-01 1991-05-29 Bioforlikelige membraner og fremgangsmÕte for fremstilling derav, samt fremgangsmÕte for fremstilling av kunstig hud
AU78066/91A AU637235B2 (en) 1990-06-01 1991-05-30 Biocompatible perforated membranes, process for their preparation , their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts
AR31981891A AR244354A1 (es) 1990-06-01 1991-05-30 Membranas perforadas biocompatibles, procedimientos para su preparacion y piel artificial obtenida a partir de las mismas.
FI912591A FI108918B (fi) 1990-06-01 1991-05-30 Biologisesti yhteen sopivat membraanit
TW80104245A TW208652B (it) 1990-06-01 1991-05-30
CA 2043527 CA2043527C (en) 1990-06-01 1991-05-30 Biocompatible perforated membranes, processes for their preparation, and uses thereof
JP12924591A JP3202257B2 (ja) 1990-06-01 1991-05-31 生物適合性の被穿孔膜
KR1019910008999A KR100195574B1 (ko) 1990-06-01 1991-05-31 생체 적합성 천공막 및 이의 제조방법
HU911834A HU215534B (hu) 1990-06-01 1991-05-31 Biokompatíbilis, perforált membránok, eljárás előállításukra, hámszövet sejtek in vitro növekedésének elősegítésére való alkalmazásuk és az így kapott mesterséges bőr
PT9783291A PT97832B (pt) 1990-06-01 1991-05-31 Processo para a preparacao de membranas biocompativeis perfuradas e de pele artificial
US08/019,818 US5326356A (en) 1990-06-01 1993-02-16 Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts
US08/209,626 US5650164A (en) 1990-06-01 1994-03-14 Process for preparing artificial skin with biocompatible perforated membranes
US08/478,541 US5658331A (en) 1990-06-01 1995-06-07 Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of epithelial cells, the artificial skin obtained in this manner, and its use in skin grafts
GR970402714T GR3025075T3 (en) 1990-06-01 1997-10-16 Biocompatible perforated membranes and their use as artificial skin

Publications (3)

Publication Number Publication Date
IT9020513D0 IT9020513D0 (it) 1990-06-01
IT9020513A1 IT9020513A1 (it) 1991-12-02
IT1248934B true IT1248934B (it) 1995-02-11

Family

ID=11168072

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2051390A IT1248934B (it) 1990-06-01 1990-06-01 Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle

Country Status (23)

Country Link
US (3) US5326356A (it)
EP (1) EP0462426B1 (it)
JP (1) JP3202257B2 (it)
KR (1) KR100195574B1 (it)
AR (1) AR244354A1 (it)
AT (1) AT156689T (it)
AU (1) AU637235B2 (it)
BR (1) BR9102225A (it)
CA (1) CA2043527C (it)
DE (2) DE69127235D1 (it)
DK (1) DK0462426T3 (it)
ES (1) ES2108019T3 (it)
FI (1) FI108918B (it)
GR (1) GR3025075T3 (it)
HU (1) HU215534B (it)
IE (1) IE911825A1 (it)
IL (1) IL98255A (it)
IT (1) IT1248934B (it)
NO (1) NO303562B1 (it)
PT (1) PT97832B (it)
SG (1) SG52545A1 (it)
TW (1) TW208652B (it)
ZA (1) ZA9104098B (it)

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CA2043527C (en) 2003-12-16
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ES2108019T3 (es) 1997-12-16
AR244354A1 (es) 1993-10-29
JP3202257B2 (ja) 2001-08-27
FI108918B1 (it)
IT9020513D0 (it) 1990-06-01
AU7806691A (en) 1991-12-05
DK0462426T3 (da) 1998-02-23
KR100195574B1 (ko) 1999-06-15
AU637235B2 (en) 1993-05-20
IE911825A1 (en) 1991-12-04
HUT60514A (en) 1992-09-28
AT156689T (de) 1997-08-15
US5658331A (en) 1997-08-19
IL98255D0 (en) 1992-06-21
NO912058D0 (no) 1991-05-29
SG52545A1 (en) 1998-09-28
DE69127235D1 (de) 1997-09-18
IL98255A (en) 1997-11-20
PT97832A (pt) 1992-02-28
TW208652B (it) 1993-07-01
NO303562B1 (no) 1998-08-03
GR3025075T3 (en) 1998-01-30
HU215534B (hu) 1999-01-28
EP0462426B1 (en) 1997-08-13
FI912591D0 (it)
CA2043527A1 (en) 1991-12-02
US5650164A (en) 1997-07-22
ZA9104098B (en) 1992-03-25
JPH04231061A (en) 1992-08-19
NO912058L (no) 1991-12-02
BR9102225A (pt) 1992-01-07
FI912591A0 (fi) 1991-05-30
US5326356A (en) 1994-07-05
HU911834D0 (en) 1991-12-30
PT97832B (pt) 1998-10-30
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