ES2082140T3 - Procedimiento para obtener proteina celular con actividad anti-hiv. - Google Patents

Procedimiento para obtener proteina celular con actividad anti-hiv.

Info

Publication number
ES2082140T3
ES2082140T3 ES91305493T ES91305493T ES2082140T3 ES 2082140 T3 ES2082140 T3 ES 2082140T3 ES 91305493 T ES91305493 T ES 91305493T ES 91305493 T ES91305493 T ES 91305493T ES 2082140 T3 ES2082140 T3 ES 2082140T3
Authority
ES
Spain
Prior art keywords
protein
hiv activity
cells
procedure
cell protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91305493T
Other languages
English (en)
Inventor
Meihan Nonoyama
Akiko Tanaka
Partrick K Lai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tampa Bay Research Institute
Original Assignee
Tampa Bay Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tampa Bay Research Institute filed Critical Tampa Bay Research Institute
Application granted granted Critical
Publication of ES2082140T3 publication Critical patent/ES2082140T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN PROCESO PARA OBTENER PROTEINA CELULAR TENIENDO UNA POTENTE ACTIVIDAD ANTI HIV COMPRENDE EL CULTIVAR CELULAS TPOSITIVAS CD4 O CELULAS MIELOIDES EN UN MEDIO DE CULTIVO DE TEJIDO BAJO CONDICIONES EN LAS QUE LAS CELULAS SON INDUCIDAS A PRODUCIR Y SEGREGAR UNA PROTEINA TENIENDO ACTIVIDAD ANTI HIV, SEPARAR LAS CELULAS DEL MEDIO DE CULTIVO CONTENIENDO LA PROTEINA Y DESPUES, RECUPERANDOLA DEL MEDIO, DONDE EL PESO MOLECULAR DE LA PROTEINA QUE TIENE ACTIVIDAD ANTI HIV, MEDIDA POR ANALISIS DE FILTRACION DE GEL ESTA EN UN PROMEDIO DE ALREDEDOR DE 7000 A ALREDEDOR DE 12000 DALTONES.
ES91305493T 1990-06-20 1991-06-18 Procedimiento para obtener proteina celular con actividad anti-hiv. Expired - Lifetime ES2082140T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54097390A 1990-06-20 1990-06-20
US07/659,564 US5346988A (en) 1990-06-20 1991-02-22 Process for obtaining cellular protein having anti-HIV activity

Publications (1)

Publication Number Publication Date
ES2082140T3 true ES2082140T3 (es) 1996-03-16

Family

ID=27066570

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91305493T Expired - Lifetime ES2082140T3 (es) 1990-06-20 1991-06-18 Procedimiento para obtener proteina celular con actividad anti-hiv.

Country Status (5)

Country Link
US (2) US5346988A (es)
EP (1) EP0462792B1 (es)
AT (1) ATE132875T1 (es)
DE (1) DE69116240T2 (es)
ES (1) ES2082140T3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346988A (en) * 1990-06-20 1994-09-13 Tampa Bay Research Institute Process for obtaining cellular protein having anti-HIV activity
US5643881A (en) * 1994-08-04 1997-07-01 Tampa Bay Research Institute Protein having anti-HIV activity and method for obtaining it
WO1996004303A1 (en) * 1994-08-04 1996-02-15 Tampa Bay Research Institute Protein having anti-retrovirus activity and method for obtaining it
RU2172322C1 (ru) 1999-12-27 2001-08-20 Энтофарм Ко., Лтд. Аллофероны-иммуномодулирующие пептиды
WO2005069190A1 (en) * 2003-12-29 2005-07-28 Nokia Corporation Apparatus, and associated method, for detecting packets
RU2276988C2 (ru) * 2004-01-15 2006-05-27 Сергей Иванович Черныш Антивирусное вещество

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683199A (en) * 1983-01-31 1987-07-28 Sloan-Kettering Institute For Cancer Research Interleukin-2 dependent cytotoxic T-cell clones
JPS59181293A (ja) * 1983-03-31 1984-10-15 Kyowa Hakko Kogyo Co Ltd 新規生理活性蛋白性物質
JPS6062997A (ja) * 1983-09-17 1985-04-11 Mochida Pharmaceut Co Ltd インタ−フエロンの生産方法
EP0193032A3 (de) * 1985-02-13 1988-04-06 Gesellschaft für Biotechnologische Forschung mbH (GBF) Zusammensetzung umfassend oder enthaltend Cytokin, Herstellungsverfahren, DNA-Sequenz und deren Verwendung
US5039794A (en) * 1986-09-19 1991-08-13 Otsuka Pharmaceutical Co., Ltd. Tumor egress factor and processes for producing the same
US4985249A (en) * 1987-06-26 1991-01-15 Hiroshi Sakagami Anti-HIV agents
JPS6490199A (en) * 1987-09-30 1989-04-06 Hiromi Fujiwara T cell growth factor derived from thymic interstitial cell and production thereof
US5346988A (en) * 1990-06-20 1994-09-13 Tampa Bay Research Institute Process for obtaining cellular protein having anti-HIV activity
US5236829A (en) * 1990-12-10 1993-08-17 The Johns Hopkins University Method of producing monokine induced by gamma interferon

Also Published As

Publication number Publication date
ATE132875T1 (de) 1996-01-15
EP0462792A3 (en) 1992-05-27
US5480782A (en) 1996-01-02
DE69116240T2 (de) 1996-05-23
US5346988A (en) 1994-09-13
EP0462792A2 (en) 1991-12-27
EP0462792B1 (en) 1996-01-10
DE69116240D1 (de) 1996-02-22

Similar Documents

Publication Publication Date Title
DK0451611T3 (da) Human hæmatopoietisk stamcelle
FR2629091B1 (fr) Procede de production de membranes poreuses, membranes poreuses obtenues par ce procede et leur utilisation comme matrices de support dans des bandelettes reactives
FI890821A (fi) Menetelmä kudossiirtoon soveltuvien, in vitro-viljeltyjen epiteelikalvojen säilyttämiseksi
DE3888642D1 (de) Rollflasche zur Züchtung von Zellengewebekulturen.
ES2120946T3 (es) Sistemas y medios de cultivo celular.
ES2147720T3 (es) Factor de celulas madre.
BR8301918A (pt) Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase
JPS5372891A (en) Purifying of microbiological enzyme extract by using synthesized high molecular electrolyte
FR2559501B1 (fr) Procede d'activation de la production de proteines par des cultures cellulaires
BE866031A (fr) Nouveaux 2-(2,2-diarylalkyl)-1-azabicyclo (2,2,2)octanes, utiles notamment comme antidiarrheiques, et leur procede de preparation
DE3061854D1 (en) Process for the preparation of interferon and culture medium composition used in it
KR840001836A (ko) 생리활성 물질의 제법
PT1200561E (pt) Clone celular recombinante estavel, sua producao e utilizacao
BE858521A (fr) Proteine specifique de tissus organiques et leur procede de preparation
ES2082140T3 (es) Procedimiento para obtener proteina celular con actividad anti-hiv.
ATE82985T1 (de) Strukturelles phosphoprotein (pp 150) des menschlichen cytomegalovirus, seine herstellung und verwendung.
SE8006993L (sv) Cellkulturmikroberare
AR214660A1 (es) Procedimiento y dispositivo para para la obtencion microbiologica de proteinas de microorganismos unicelulares a partir de etanol
DE3871530D1 (de) Vorrichtung zum kultivieren von ruhenden zellen in einem bioreaktor.
ES2052883T3 (es) Cultivo de celulas de riñon de cerdo y su uso en la produccion de vacunas.
DE2966082D1 (en) Process for growing human epidermal cells in tissue culture
ES2047946T3 (es) Metodos de cultivos celulares para producir proteina c activada.
FR2612186B1 (fr) Carbonyl 2,2' bis (alkyl-4 oxadiazolidines-1,2,4-diones-3,5), leur procede de preparation et leur utilisation comme intermediaires de synthese dans la preparation de carbamates
FR2555577B1 (fr) Nouveaux derives de peptides, leur procede de preparation et leur emploi comme reactif biologique
JPS52148683A (en) Treatment of microbial cultivation liquid

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 462792

Country of ref document: ES