JP2001504106A - 口部に適用される瞬時湿潤性の水溶性薄膜または水溶性層 - Google Patents
口部に適用される瞬時湿潤性の水溶性薄膜または水溶性層Info
- Publication number
- JP2001504106A JP2001504106A JP52208898A JP52208898A JP2001504106A JP 2001504106 A JP2001504106 A JP 2001504106A JP 52208898 A JP52208898 A JP 52208898A JP 52208898 A JP52208898 A JP 52208898A JP 2001504106 A JP2001504106 A JP 2001504106A
- Authority
- JP
- Japan
- Prior art keywords
- water
- film
- mixture
- composition according
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
- A61K8/8176—Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.粘膜接着性フィルムからなる口腔に適用できる組成物であって、前記粘膜接 着性フィルムが水溶性ポリマー、ポリアルコール、化粧用および/または薬剤用 の活性剤、および香味料からなる均質な混合物を含む組成物。 2.前記水溶性ポリマーがヒドロキシプロピルメチルセルロース、ヒドロキシエ チルセルロース、ヒドロキシプロピルセルロース、ポリビニルピロリドン、カル ボキシメチルセルロース、ポリビニルアルコール、アルギン酸ナトリウム、ポリ エチレングリコール、キサンゴム、トラガカントゴム、グアーゴム、アカシアゴ ム、アラビアゴム、ポリアクリル酸、メチルメタクリレート共重合体、カルボキ シビニル共重合体類、またはそれらの混合物である請求項1に記載の組成物。 3.乾燥した前記フィルムにおける前記水溶性ポリマーの濃度が20%以上75 %以下の範囲である請求項1に記載の組成物。 4.前記混合物が任意の成分として1つ以上の可塑剤または界面活性剤を含む請 求項1に記載の組成物。 5.前記界面活性剤混合物の第1成分がポリオキシエチレンソルビタン脂肪酸エ ステルまたはα−ハイドロ−ω−ヒドロキシポリ(オキシエチレン)ポリ(オキ シプロピレン)ポリ(オキシエチレン)ブロック共重合体である請求項4に記載 の組成物。 6.前記界面活性剤混合物の第2成分がポリオキシエチレンアルキルエーテルま たはポリオキシエチレンひまし油誘導体である請求項4に記載の組成物。 7.前記ポリアルコールがグリセロール、ポリエチレングリコール、プロピレン グリコール、または脂肪酸類を有するグリセロールモノエステル類から選択され る請求項1に記載の組成物。 8.前記治療薬が睡眠薬、鎮静薬、抗てんかん薬、覚醒剤、向精神神経薬、神経 筋遮断薬、鎮痙薬、抗ヒスタミン薬、抗アレルギー薬、強心薬、不整脈治療薬、 利尿薬、降圧薬、昇圧薬、鎮咳性去痰薬、甲状腺ホルモン、性ホルモン、抗糖尿 病薬、抗腫瘍薬、抗生物質および化学療法薬、または麻酔薬から選択される請求 項1に記載の組成物。 9.前記化粧用活性剤がメントールに代表される呼気清涼化合物、または口腔衛 生用に通常使用されるその他の香味料または芳香剤、および/または第四級アン モニウム塩基類に代表される歯および/または口腔の清浄に用いられる薬剤を含 む請求項1に記載の組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19646392.0 | 1996-11-11 | ||
DE19646392A DE19646392A1 (de) | 1996-11-11 | 1996-11-11 | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
PCT/EP1997/005820 WO1998020862A1 (de) | 1996-11-11 | 1997-10-22 | Sofortige benetzbarkeit aufweisende(r) wasserlöslicher film oder wasserlösliche schicht zur oralen applikation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2005161714A Division JP4817721B2 (ja) | 1996-11-11 | 2005-06-01 | 口腔内に活性物質であるニコチンを放出するための口部に適用される組成物及びその製造方法 |
Publications (2)
Publication Number | Publication Date |
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JP2001504106A true JP2001504106A (ja) | 2001-03-27 |
JP4063331B2 JP4063331B2 (ja) | 2008-03-19 |
Family
ID=7811214
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52208898A Expired - Lifetime JP4063331B2 (ja) | 1996-11-11 | 1997-10-22 | 口部に適用される瞬時湿潤性の水溶性薄膜または水溶性層 |
JP2005161714A Expired - Fee Related JP4817721B2 (ja) | 1996-11-11 | 2005-06-01 | 口腔内に活性物質であるニコチンを放出するための口部に適用される組成物及びその製造方法 |
JP2009222637A Pending JP2010006832A (ja) | 1996-11-11 | 2009-09-28 | 口腔内に活性物質であるニコチンを放出するための口部に適用される組成物及びその製造方法 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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JP2005161714A Expired - Fee Related JP4817721B2 (ja) | 1996-11-11 | 2005-06-01 | 口腔内に活性物質であるニコチンを放出するための口部に適用される組成物及びその製造方法 |
JP2009222637A Pending JP2010006832A (ja) | 1996-11-11 | 2009-09-28 | 口腔内に活性物質であるニコチンを放出するための口部に適用される組成物及びその製造方法 |
Country Status (26)
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US (8) | US5948430A (ja) |
EP (2) | EP0936905B1 (ja) |
JP (3) | JP4063331B2 (ja) |
KR (2) | KR100569847B1 (ja) |
AT (2) | ATE422157T1 (ja) |
AU (1) | AU739698B2 (ja) |
CA (1) | CA2265651C (ja) |
CZ (1) | CZ297354B6 (ja) |
DE (4) | DE19646392A1 (ja) |
DK (2) | DK1362584T3 (ja) |
ES (2) | ES2206692T3 (ja) |
HK (1) | HK1035316A1 (ja) |
HU (2) | HU228464B1 (ja) |
ID (1) | ID22526A (ja) |
IL (2) | IL129819A0 (ja) |
MY (1) | MY125548A (ja) |
NO (2) | NO325073B1 (ja) |
NZ (1) | NZ335063A (ja) |
PL (1) | PL190376B1 (ja) |
PT (2) | PT936905E (ja) |
SI (1) | SI0936905T1 (ja) |
SK (2) | SK285999B6 (ja) |
TR (1) | TR199901633T2 (ja) |
TW (2) | TWI250029B (ja) |
WO (1) | WO1998020862A1 (ja) |
ZA (1) | ZA9710093B (ja) |
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- 1997-10-22 WO PCT/EP1997/005820 patent/WO1998020862A1/de active IP Right Grant
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- 1997-10-22 CZ CZ0164799A patent/CZ297354B6/cs not_active IP Right Cessation
- 1997-10-22 DK DK03014213T patent/DK1362584T3/da active
- 1997-10-22 HU HU0500666A patent/HU230022B1/hu unknown
- 1997-10-22 DK DK97911237T patent/DK0936905T3/da active
- 1997-10-22 AU AU48682/97A patent/AU739698B2/en not_active Ceased
- 1997-10-22 PT PT03014213T patent/PT1362584E/pt unknown
- 1997-10-22 SI SI9730590T patent/SI0936905T1/xx unknown
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1999
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2004
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2005
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