KR930007445A - 국소 적용 배합물의 침투 증가방법 - Google Patents
국소 적용 배합물의 침투 증가방법 Download PDFInfo
- Publication number
- KR930007445A KR930007445A KR1019920019450A KR920019450A KR930007445A KR 930007445 A KR930007445 A KR 930007445A KR 1019920019450 A KR1019920019450 A KR 1019920019450A KR 920019450 A KR920019450 A KR 920019450A KR 930007445 A KR930007445 A KR 930007445A
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- topical application
- solvent
- vitamin
- penetration
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
치료학적 유효(화장품용 또는 약리학적 활성)약물 또는 화장품 성분의 침투를 증가시키는 목적으로 적용 조성물에 비타민 E를 사용하는 것이 개시된다. 비타민 E를 침투-증가 농도로 함유한 국소 조성물은 반고체(겔, 페이스트, 크림, 로션, 연고, 등), 액제, 분산액, 필름 또는 라미네이트를 비롯한 다양한 형태로 제공될 수 있다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (22)
- 조성물에 비타민 E를 침투-증가시키는 양으로 포함시키는 것으로 이루어진 치료 활성제로 된 국소 적용조성물의 침투-증가 방법.
- 제1항에 있어서, 비타민 E가 유리 알코올, 리놀레이트, 니코티네이트, 아세테이트 또는 산 숙시네이트 에스테르의 형태인 것이 특징인 침투-증가 방법.
- 제2항에 있어서,침투-증가 양이 조성물의 약 0.01-20중량%인 것이 특징인 침투-증가 방법.
- 제3항에 있어서, 침투-증가 양이 조성물의 약 0.1-15중량%인 것이 특징인 침투-증가 방법.
- 제4항에 있어서, 국소 적용 조성물이 점막 점착성 부형제로 이루어진 것이 특징인 침투-증가 방법.
- 제1항에 있어서, 치료 활성제가 약리 활성제인 것이 특징인 침투-증가 방법.
- 제6항에 있어서, 상기 조성물이 겔, 페이스트, 연고, 크림, 로션, 액제, 분산액, 좌제, 필름 또는 라미네이트의 형태인 것이 특징인 침투-증가 방법.
- 제1항에 있어서, 국소 적용 조성물이 점막 점착성 부형제로 이루어진 것이 특징인 침투-증가 방법.
- 제1항에 있어서, 국소 적용 조성물이 용매를 함유하는 것이 특징인 침투-증가 방법.
- 제9항에 있어서, 용매가 미네랄 오일, 물, 에탄올, 트리아세틴, 글리세린 및 프로필렌 글리콜중에서 적어도 한가지 성분인 것이 특징인 침투-증가 방법.
- 제9항에 있어서, 국소 적용 조성물이 점착제를 포함하는 것이 특징인 침투-증가 방법.
- 제11항에 있어서, 점착제가 폴리이소부틸렌인 것이 특징인 침투-증가 방법.
- 제12항에 있어서, 용매가 미네랄 오일인 것이 특징인 침투-증가 방법.
- 제1항에 있어서, 상기 조성물이 약리적으로 허용되는 중점제를 포함하는 것이 특징인 침투-증가 방법.
- 제14항에 있어서, 중점제가 폴리옥시에틸렌과 폴리옥시프로필렌의 블록 코폴리머인 것이 특징인 침투-증가 방법.
- 제15항에 있어서, 조성물이 물을 함유하는 것이 특징인 침투-증가 방법.
- 제14항에 있어서, 중점제가 히드록시프로필 셀룰로스이며 조성물이 용매로서 프로필렌 글리콜을 함유하는 것이 특징인 침투-증가 방법.
- 제11항에 있어서, 점착제가 폴리비닐 아세테이트이며 용매가 트리아세틴으로 이루어지는 것이 특징인 침투-증가 방법.
- 제11항에 있어서, 점착제가 폴리비닐 알코올이며 용매가 글리세린인 것이 특징인 침투-증가 방법.
- 제1항에 있어서, 국소 적용 조성물이 화장품을 활성제와 침투-증가 양의비타민 E로 이루어지는 것이 특징인 침투-증가 방법.
- 제1항에 있어서, 조성물이 비타민 E인 약리적으로 허용되는 부형제를 함유하는 것이 특징인 침투-증가 방법.
- ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78542691A | 1991-10-23 | 1991-10-23 | |
US07/785,426 | 1991-10-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR930007445A true KR930007445A (ko) | 1993-05-20 |
Family
ID=25135484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019920019450A KR930007445A (ko) | 1991-10-23 | 1992-10-22 | 국소 적용 배합물의 침투 증가방법 |
Country Status (11)
Country | Link |
---|---|
US (1) | US6017520A (ko) |
EP (1) | EP0539215B1 (ko) |
JP (1) | JP2671248B2 (ko) |
KR (1) | KR930007445A (ko) |
AT (1) | ATE169228T1 (ko) |
AU (1) | AU658681B2 (ko) |
CA (1) | CA2081269C (ko) |
DE (1) | DE69226491T2 (ko) |
DK (1) | DK0539215T3 (ko) |
ES (1) | ES2119800T3 (ko) |
NZ (1) | NZ244862A (ko) |
Families Citing this family (34)
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US5683711A (en) * | 1993-04-20 | 1997-11-04 | Hexal Pharma Gmbh | Active ingredient patch |
CA2166722A1 (en) * | 1994-05-06 | 1995-11-16 | Manoj L. Maniar | Use of vitamin e tocopheryl derivatives in ophthalmic compositions |
GB9409778D0 (en) | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
WO1996020712A1 (en) * | 1994-12-30 | 1996-07-11 | American Home Products Corporation | Clear non-alcoholic hydrocortisone solutions |
EP0766960B1 (en) | 1995-04-21 | 2003-09-17 | Sekisui Kagaku Kogyo Kabushiki Kaisha | External preparations for treating dermatoses |
BR9710407A (pt) * | 1996-03-14 | 1999-08-17 | Johnson & Johnson Consumer | Composi-{es tensoativas de limpeza e umecta-Æo |
US6730679B1 (en) | 1996-03-22 | 2004-05-04 | Smithkline Beecham Corporation | Pharmaceutical formulations |
IT1282778B1 (it) * | 1996-05-31 | 1998-03-31 | Giorgio Panin | Vitamina "e" acetato quale prodotto per applicazione topica |
DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
AUPO379596A0 (en) | 1996-11-22 | 1996-12-19 | Soltec Research Pty Ltd | Percutaneous delivery system |
US20040067212A1 (en) * | 1998-03-11 | 2004-04-08 | Kabushiki Kaisha Soken | Skin conditioner |
KR20000000840A (ko) * | 1998-06-03 | 2000-01-15 | 김영대 | 신규한 폴리옥시프로필렌폴리옥시에틸렌 비타민 e 및 그의제조방법 |
FR2761600B1 (fr) | 1998-06-19 | 2000-03-31 | Oreal | Composition moussante pour le lavage et le traitement des cheveux et/ou du cuir chevelu a base d'un principe actif, d'un tensioactif anionique, d'un tensioactif amphotere et d'un agent propenetrant |
US6486207B2 (en) | 1998-12-10 | 2002-11-26 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US6825234B2 (en) | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US20070191320A1 (en) * | 1998-12-10 | 2007-08-16 | Nexmed Holdings, Inc. | Methods of treatment for female sexual arousal disorder |
EP1152742A1 (en) * | 1999-02-12 | 2001-11-14 | The Procter & Gamble Company | Cosmetic compositions containing vitamin b3 compounds |
US6787342B2 (en) * | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
US6383505B1 (en) | 2000-11-09 | 2002-05-07 | Steris Inc | Fast-acting antimicrobial lotion with enhanced efficacy |
US6429231B1 (en) * | 2001-09-24 | 2002-08-06 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
ATE419835T1 (de) * | 2002-05-06 | 2009-01-15 | Elan Pharma Int Ltd | Nystatin-nanopartikelzusammensetzungen |
AU2003240824B9 (en) * | 2002-05-31 | 2008-09-25 | University Of Mississippi | Transmucosal delivery of cannabinoids |
DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
JP2004123633A (ja) * | 2002-10-03 | 2004-04-22 | Medorekkusu:Kk | 外用製剤 |
US7374772B2 (en) * | 2002-11-07 | 2008-05-20 | Bommarito Alexander A | Topical antifungal treatment |
US20040191279A1 (en) * | 2003-03-28 | 2004-09-30 | Klofta Thomas James | Tacky skin care compositions and articles having tacky skin care compositions disposed thereon |
AU2004279389B2 (en) * | 2003-10-03 | 2008-03-06 | Noxell Corporation | Topical composition |
US9314431B2 (en) * | 2005-02-14 | 2016-04-19 | Transdermal Corp | Solubilized benzoyl small molecule |
US20090304820A1 (en) * | 2008-06-05 | 2009-12-10 | Pankaj Modi | Solubilized benzoyl peroxide topical drug formulation for the treatment of acne |
US9308268B2 (en) * | 2005-02-14 | 2016-04-12 | Transdermal Corp | Solubilized benzoyl peroxyde acne |
US7563464B1 (en) * | 2005-04-22 | 2009-07-21 | Bruce Eric Hudkins | Treatment of mucosal membranes utilizing phytoestrogen |
WO2008037809A1 (en) * | 2006-09-29 | 2008-04-03 | Abbott Gmbh & Co. Kg | Transmucosal administration of fibrate compounds and delivery system therefor |
CA2719512A1 (en) | 2010-11-01 | 2012-05-01 | Stiefel Research Australia Pty Ltd | Polymeric topical compositions |
WO2018122344A1 (en) | 2016-12-29 | 2018-07-05 | Nestlé Skin Health Sa | Composition comprising a crosslinked hyaluronic acid (ha) in combination with a low-molecular ha and/or an agent stimulating endogenous ha synthesis |
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US4177267A (en) * | 1963-12-09 | 1979-12-04 | Crown Zellerbach | Enhancing tissue penetration of physiologically active steroidal agents with DMSC |
IN142640B (ko) * | 1975-01-17 | 1977-08-06 | Johnson & Johnson | |
JPS5579318A (en) * | 1978-12-07 | 1980-06-14 | Taisho Pharmaceut Co Ltd | Poultice |
JPS5610887A (en) * | 1979-07-09 | 1981-02-03 | Babcock Hitachi Kk | Handrall structure of joint portion of duct |
JPS5855417A (ja) * | 1981-09-27 | 1983-04-01 | Nitto Electric Ind Co Ltd | 医薬組成物 |
ATE82684T1 (de) * | 1984-03-07 | 1992-12-15 | Roshdy Ismail | Mittel zur behandlung und zum schutz der haut. |
JPS60224638A (ja) * | 1984-04-23 | 1985-11-09 | Kao Corp | 経皮吸収促進剤およびこれを含有する外用剤 |
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GB8630721D0 (en) * | 1986-12-23 | 1987-02-04 | Unilever Plc | Cosmetic compositions |
US4847069A (en) * | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising sorbohydroxamic acid and an anti-inflammatory agent |
US4869897A (en) * | 1987-10-22 | 1989-09-26 | The Procter & Gamble Company | Photoprotection compositions comprising sorbohydroxamic acid |
JP2663136B2 (ja) * | 1988-05-02 | 1997-10-15 | 有限会社野々川商事 | 美白化粧料 |
EP0356382B1 (de) * | 1988-08-02 | 1994-02-16 | Ciba-Geigy Ag | Mehrschichtiges Pflaster |
JPH06509559A (ja) * | 1991-03-19 | 1994-10-27 | セラピューティック パッチ リサーチ エヌ.ブイ. | 膜透過エンハンサーとしてのアミノアルコール誘導体組成物及び方法 |
US5215759A (en) * | 1991-10-01 | 1993-06-01 | Chanel, Inc. | Cosmetic composition |
-
1992
- 1992-10-22 AU AU27266/92A patent/AU658681B2/en not_active Expired
- 1992-10-22 JP JP4307998A patent/JP2671248B2/ja not_active Expired - Lifetime
- 1992-10-22 NZ NZ244862A patent/NZ244862A/en not_active IP Right Cessation
- 1992-10-22 KR KR1019920019450A patent/KR930007445A/ko active IP Right Grant
- 1992-10-23 DE DE69226491T patent/DE69226491T2/de not_active Revoked
- 1992-10-23 EP EP92309727A patent/EP0539215B1/en not_active Revoked
- 1992-10-23 AT AT92309727T patent/ATE169228T1/de not_active IP Right Cessation
- 1992-10-23 DK DK92309727T patent/DK0539215T3/da active
- 1992-10-23 CA CA002081269A patent/CA2081269C/en not_active Expired - Lifetime
- 1992-10-23 ES ES92309727T patent/ES2119800T3/es not_active Expired - Lifetime
-
1997
- 1997-05-02 US US08/850,377 patent/US6017520A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69226491T2 (de) | 1999-01-14 |
JPH06128176A (ja) | 1994-05-10 |
CA2081269A1 (en) | 1993-04-24 |
AU658681B2 (en) | 1995-04-27 |
ATE169228T1 (de) | 1998-08-15 |
CA2081269C (en) | 2002-03-05 |
NZ244862A (en) | 1995-07-26 |
DK0539215T3 (da) | 1999-05-03 |
ES2119800T3 (es) | 1998-10-16 |
AU2726692A (en) | 1993-04-29 |
EP0539215A1 (en) | 1993-04-28 |
JP2671248B2 (ja) | 1997-10-29 |
EP0539215B1 (en) | 1998-08-05 |
US6017520A (en) | 2000-01-25 |
DE69226491D1 (de) | 1998-09-10 |
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