JO3032B1 - مركبات سبيرو – اوكسندول وإستعمالاتها كعوامل علاجية. - Google Patents

مركبات سبيرو – اوكسندول وإستعمالاتها كعوامل علاجية.

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Publication number
JO3032B1
JO3032B1 JOP/2009/0380A JOP20090380A JO3032B1 JO 3032 B1 JO3032 B1 JO 3032B1 JO P20090380 A JOP20090380 A JO P20090380A JO 3032 B1 JO3032 B1 JO 3032B1
Authority
JO
Jordan
Prior art keywords
spiro
therapeutic agents
oxindole compounds
oxindole
compounds
Prior art date
Application number
JOP/2009/0380A
Other languages
English (en)
Inventor
Zenova Alla
Hsieh Tom
Langille Jonathan
Cadieux Jean-Jacques
Fu Jianmin
Sun Jianyu
Cikojevic Zoran
Chowdhury Sultan
Sviridov Serguei
J Gauthier Simon
Sun Shaoyi
Liu Shifeng
Jia Qi
Fraser Lauren
Wood Mark
Chafeev Mikhail
Chakka Nagasree
Original Assignee
Xenon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41395034&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3032(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenon Pharmaceuticals Inc filed Critical Xenon Pharmaceuticals Inc
Application granted granted Critical
Publication of JO3032B1 publication Critical patent/JO3032B1/ar

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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Abstract

يتعلق الاختراع الحالي بمركبات سبيرو أوكسيندول مثل مزدوجات تجاسم متشاكلات مركبات صنوية منه أو خلائط منه؛ أو أملاح مقبولة صيدلانيا منها و ذوابات أو عقاقير أولية منها لعلاج و/أو الوقاية من الأمراض أو الحالات التي تسببها قناة الصوديوم مثل الألم
JOP/2009/0380A 2008-10-17 2009-10-13 مركبات سبيرو – اوكسندول وإستعمالاتها كعوامل علاجية. JO3032B1 (ar)

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