US7205307B2
(en)
*
|
2002-02-14 |
2007-04-17 |
Icagen, Inc. |
Pyrimidines as novel openers of potassium ion channels
|
MXPA05000200A
(es)
*
|
2002-07-02 |
2005-06-06 |
Schering Corp |
Nuevos antagonistas del receptor neuropeptido y y5.
|
US7186735B2
(en)
*
|
2002-08-07 |
2007-03-06 |
Sanofi-Aventis Deutschland Gmbh |
Acylated arylcycloalkylamines and their use as pharmaceuticals
|
EP1388535A1
(de)
*
|
2002-08-07 |
2004-02-11 |
Aventis Pharma Deutschland GmbH |
Acylierte Arylcycloalkylamine und ihre Anwendung als Arzneimittelwirkstoff
|
GB0219961D0
(en)
*
|
2002-08-28 |
2002-10-02 |
Pfizer Ltd |
Oxytocin inhibitors
|
JP2006519755A
(ja)
*
|
2002-11-20 |
2006-08-31 |
ロレアル |
ピラゾール−カルボキシアミドを含有する毛髪の手入れ用又は睫毛用の組成物、毛髪及び睫毛の成長を刺激し、及び/又は抜毛を防止するためのそれらの使用
|
AU2004209495A1
(en)
|
2003-02-07 |
2004-08-19 |
Daiichi Pharmaceutical Co., Ltd. |
Pyrazole derivative
|
US7531558B2
(en)
*
|
2003-02-14 |
2009-05-12 |
Glaxo Group Limited |
Carboxamide derivatives
|
SE0300705D0
(sv)
*
|
2003-03-14 |
2003-03-14 |
Biolipox Ab |
New compounds
|
WO2004089896A1
(en)
*
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ACTIVE COMPOUNDS
|
AR045979A1
(es)
*
|
2003-04-28 |
2005-11-23 |
Astrazeneca Ab |
Amidas heterociclicas
|
US20040220170A1
(en)
*
|
2003-05-01 |
2004-11-04 |
Atkinson Robert N. |
Pyrazole-amides and sulfonamides as sodium channel modulators
|
SI1618092T1
(sl)
*
|
2003-05-01 |
2010-11-30 |
Bristol Myers Squibb Co |
Aril substituirane pirazolamidne spojine uporabnekot kinazni inhibitorji
|
WO2004108133A2
(en)
*
|
2003-06-05 |
2004-12-16 |
Vertex Pharmaceuticals Incorporated |
Modulators of vr1 receptor
|
JP2007506741A
(ja)
*
|
2003-09-23 |
2007-03-22 |
メルク エンド カムパニー インコーポレーテッド |
向代謝性グルタミン酸受容体のピラゾール系調節剤
|
DE10360369A1
(de)
*
|
2003-12-22 |
2005-07-14 |
Bayer Cropscience Ag |
Amide
|
AU2005214375A1
(en)
*
|
2004-02-18 |
2005-09-01 |
Astrazeneca Ab |
Triazole compounds and their use as metabotropic glutamate receptor antagonists
|
US7687533B2
(en)
|
2004-03-18 |
2010-03-30 |
Pfizer Inc. |
N-(1-arylpyrazol-4l) sulfonamides and their use as parasiticides
|
EA201890903A9
(ru)
*
|
2004-09-02 |
2021-11-10 |
Дженентек, Инк. |
Соединения пиридиловых ингибиторов передачи сигналов белком hedgehog, способ их получения, композиция и способы лечения рака и ингибирований ангиогенеза и сигнального пути hedgehog в клетках на их основе
|
JP2008513426A
(ja)
|
2004-09-20 |
2008-05-01 |
バイオリポックス エービー |
炎症の治療に有用なピラゾール化合物
|
US20080090836A1
(en)
*
|
2004-09-20 |
2008-04-17 |
Peter Nilsson |
Pyrazole Compounds Useful In The Treatment Of Inflammation
|
AU2005293336B2
(en)
|
2004-10-12 |
2009-05-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
WO2006089076A2
(en)
|
2005-02-18 |
2006-08-24 |
Neurogen Corporation |
Thiazole amides, imidazole amides and related analogues
|
AR053710A1
(es)
|
2005-04-11 |
2007-05-16 |
Xenon Pharmaceuticals Inc |
Compuestos espiroheterociclicos y sus usos como agentes terapeuticos
|
AR056968A1
(es)
|
2005-04-11 |
2007-11-07 |
Xenon Pharmaceuticals Inc |
Compuestos espiro-oxindol y composiciones farmacéuticas
|
US20090131412A1
(en)
*
|
2005-06-07 |
2009-05-21 |
Dainippon Sumitomo Pharma Co., Ltd. |
Novel 2-quinolone derivative
|
CN1884262B
(zh)
*
|
2005-06-24 |
2014-06-25 |
中国人民解放军军事医学科学院毒物药物研究所 |
4-氨基哌啶类化合物及其医药用途
|
JP5261176B2
(ja)
*
|
2005-08-16 |
2013-08-14 |
アイカジェン, インコーポレイテッド |
電位作動型ナトリウムチャンネル阻害剤
|
EP1772449A1
(de)
*
|
2005-10-05 |
2007-04-11 |
Bayer CropScience S.A. |
N-alkyl-heterocyclische carboxamide Derivate
|
WO2007073432A2
(en)
*
|
2005-10-11 |
2007-06-28 |
Chemocentryx, Inc. |
Piperidine derivatives and methods of use
|
TW200800911A
(en)
*
|
2005-10-20 |
2008-01-01 |
Biolipox Ab |
Pyrazoles useful in the treatment of inflammation
|
EP1943234A1
(de)
*
|
2005-10-31 |
2008-07-16 |
Biolipox AB |
Triazolverbindungen als lipoxygenaseinhibitoren
|
TW200732320A
(en)
*
|
2005-10-31 |
2007-09-01 |
Biolipox Ab |
Pyrazoles useful in the treatment of inflammation
|
EP1943225A1
(de)
*
|
2005-11-01 |
2008-07-16 |
Biolipox AB |
Bei der behandlung von entzündungen geeignete pyrazole
|
EP1787981A1
(de)
*
|
2005-11-22 |
2007-05-23 |
Bayer CropScience S.A. |
Neue N-phenethylcarboxamidderivate
|
JP2009523748A
(ja)
*
|
2006-01-18 |
2009-06-25 |
シエナ ビオテク ソシエタ ペル アチオニ |
α7ニコチン性アセチルコリン受容体の調節物質およびそれらの治療への使用
|
FR2897061B1
(fr)
|
2006-02-03 |
2010-09-03 |
Sanofi Aventis |
Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique.
|
UY30183A1
(es)
|
2006-03-02 |
2007-10-31 |
Astrazeneca Ab |
Derivados de quinolina
|
SI1999114T1
(sl)
|
2006-03-22 |
2015-10-30 |
F. Hoffmann-La Roche Ag |
Pirazoli kot 11-beta-hsd-1
|
US8841483B2
(en)
|
2006-04-11 |
2014-09-23 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of voltage-gated sodium channels
|
JP5290965B2
(ja)
*
|
2006-06-08 |
2013-09-18 |
シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト |
N−(1−アルキル−2−フェニルエチル)−カルボキサミド誘導体と、それを殺真菌剤として利用する方法
|
EA200900072A1
(ru)
|
2006-07-07 |
2009-06-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Фенилзамещенные гетероарильные производные и их применение в качестве противоопухолевых средств
|
CA2657247A1
(en)
|
2006-07-28 |
2008-01-31 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
EP2065369A4
(de)
*
|
2006-08-23 |
2011-12-28 |
Astellas Pharma Inc |
Harnstoffverbindung oder salz davon
|
BRPI0718515A2
(pt)
|
2006-09-25 |
2013-11-19 |
Boehringer Ingelheim Int |
Compostos que modulam o receptor cb2
|
EP2079728B1
(de)
*
|
2006-10-10 |
2013-09-25 |
Amgen Inc. |
N-arylpyrazolverbindungen zur verwendung gegen diabetes
|
TW200833695A
(en)
|
2006-10-12 |
2008-08-16 |
Xenon Pharmaceuticals Inc |
Use of spiro-oxindole compounds as therapeutic agents
|
WO2008046084A2
(en)
*
|
2006-10-12 |
2008-04-17 |
Xenon Pharmaceuticals Inc. |
Spiroheterocyclic compounds and their uses as therapeutic agents
|
US8173638B2
(en)
*
|
2006-11-21 |
2012-05-08 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the CB2 receptor
|
JP2010043004A
(ja)
*
|
2006-12-06 |
2010-02-25 |
Dainippon Sumitomo Pharma Co Ltd |
新規2環性複素環化合物
|
CL2008000512A1
(es)
|
2007-02-22 |
2008-08-29 |
Bayer Cropscience Sa |
Compuestos derivados de n-(3-fenilpropil)carboxamida; procedimiento de preparacion de dichos compuestos; composicion fungicida; y metodo para combatir de forma preventiva o curativa los hongos fitopatogenos de cultivos.
|
WO2008135826A2
(en)
*
|
2007-05-03 |
2008-11-13 |
Pfizer Limited |
2 -pyridine carboxamide derivatives as sodium channel modulators
|
CL2008001647A1
(es)
|
2007-06-08 |
2008-10-10 |
Syngenta Participations Ag |
Compuestos derivados de feniletil-amida de acido-1h-pirazol-4-carboxilico; compuestos derivados de (feniletil)amina; metodo para controlar o prevenir la infestacion de plantas por parte de microorganismos fitopatogenos; y composicion para el control
|
CL2008001943A1
(es)
|
2007-07-02 |
2009-09-11 |
Boehringer Ingelheim Int |
Compuestos derivados de fenil-triazol, inhibidores de enzimas de señales especificas que participan del control de la proliferacion celular; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar cancer, infecciones, enfermedades inflamatorias y autoinmunes.
|
ES2523196T3
(es)
*
|
2007-07-13 |
2014-11-21 |
Icagen, Inc. |
Inhibidores de los canales de sodio
|
EP2178865B1
(de)
|
2007-07-19 |
2015-08-19 |
Lundbeck, H., A/S |
Fünfteilige heterozyklische amide und entsprechende verbindungen
|
US7977358B2
(en)
|
2007-07-26 |
2011-07-12 |
Hoffmann-La Roche Inc. |
Pyrazol derivatives
|
EP2212290B1
(de)
|
2007-10-11 |
2014-12-03 |
Vertex Pharmaceuticals Incorporated |
Als inhibitoren von spannungsabhängigen natriumkanälen geeignete arylamide
|
WO2009049181A1
(en)
|
2007-10-11 |
2009-04-16 |
Vertex Pharmaceuticals Incorporated |
Amides useful as inhibitors of voltage-gated sodium channels
|
CA2701946A1
(en)
*
|
2007-10-11 |
2009-04-16 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl amides useful as inhibitors of voltage-gated sodium channels
|
CA2704684A1
(en)
|
2007-11-07 |
2009-05-14 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
CA2714591A1
(en)
|
2008-02-13 |
2009-08-20 |
Eisai R&D Management Co., Ltd. |
Bicycloamine derivative
|
DE102008015032A1
(de)
|
2008-03-17 |
2009-09-24 |
Aicuris Gmbh & Co. Kg |
Substituierte Pyrazolamide und ihre Verwendung
|
DE102008015033A1
(de)
|
2008-03-17 |
2009-09-24 |
Aicuris Gmbh & Co. Kg |
Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
|
US9206143B2
(en)
|
2008-03-19 |
2015-12-08 |
Aurimmed Pharma, Inc. |
Compounds advantageous in the treatment of central nervous system diseases and disorders
|
US10793515B2
(en)
|
2008-03-19 |
2020-10-06 |
Aurimmed Pharma, Inc. |
Compounds advantageous in the treatment of central nervous system diseases and disorders
|
US9212155B2
(en)
|
2008-03-19 |
2015-12-15 |
Aurimmed Pharma, Inc. |
Compounds advantageous in the treatment of central nervous system diseases and disorders
|
US20090281089A1
(en)
*
|
2008-04-11 |
2009-11-12 |
Genentech, Inc. |
Pyridyl inhibitors of hedgehog signalling
|
JP5216912B2
(ja)
*
|
2008-04-29 |
2013-06-19 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ccr1受容体拮抗薬としてのインダゾール化合物
|
CA2722811C
(en)
*
|
2008-05-06 |
2016-07-05 |
Boehringer Ingelheim International Gmbh |
Pyrazole compounds as ccr1 antagonists
|
UY31907A
(es)
|
2008-06-19 |
2010-01-29 |
Takeda Pharmaceutical |
Compuesto heterociclico y su uso
|
CA2730037A1
(en)
|
2008-07-10 |
2010-01-14 |
Boehringer Ingelheim International Gmbh |
Sulfone compounds which modulate the cb2 receptor
|
PE20110397A1
(es)
|
2008-09-25 |
2011-07-01 |
Boehringer Ingelheim Int |
Compuestos que modulan selectivamente el receptor cb2
|
EP2346868B1
(de)
*
|
2008-09-26 |
2016-01-27 |
Boehringer Ingelheim International Gmbh |
Azaindazolverbindungen als ccr1-rezeptorantagonisten
|
AU2009295855A1
(en)
|
2008-09-29 |
2010-04-01 |
Boehringer Ingelheim International Gmbh |
Antiproliferative compounds
|
CA2741024A1
(en)
|
2008-10-17 |
2010-04-22 |
Xenon Pharmaceuticals Inc. |
Spiro-oxindole compounds and their use as therapeutic agents
|
CN103664973B
(zh)
|
2008-10-17 |
2017-04-19 |
泽农医药公司 |
螺羟吲哚化合物及其作为治疗剂的用途
|
DE102008062863A1
(de)
|
2008-12-17 |
2010-06-24 |
Aicuris Gmbh & Co. Kg |
Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
|
DE102008062878A1
(de)
|
2008-12-17 |
2010-06-24 |
Aicuris Gmbh & Co. Kg |
Substituierte Furancarboxamide und ihre Verwendung
|
WO2010080357A1
(en)
*
|
2008-12-18 |
2010-07-15 |
Boehringer Ingelheim International Gmbh |
Serotonin 5-ht2b receptor inhibitors
|
US20110269788A1
(en)
|
2008-12-29 |
2011-11-03 |
Xenon Pharmaceuticals Inc. |
Spiro-oxindole-derivatives as sodium channel blockers
|
CA2761639C
(en)
|
2009-05-29 |
2016-06-07 |
Raqualia Pharma Inc. |
Aryl substituted carboxamide derivatives as calcium or sodium channel blockers
|
US8299103B2
(en)
|
2009-06-15 |
2012-10-30 |
Boehringer Ingelheim International Gmbh |
Compounds which selectively modulate the CB2 receptor
|
WO2010147791A1
(en)
|
2009-06-16 |
2010-12-23 |
Boehringer Ingelheim International Gmbh |
Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor
|
AR077252A1
(es)
|
2009-06-29 |
2011-08-10 |
Xenon Pharmaceuticals Inc |
Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
|
DE102009036604A1
(de)
|
2009-07-30 |
2011-02-03 |
Aicuris Gmbh & Co. Kg |
Substituierte Bis-Arylpyrazolamide mit terminaler primärer Amidfunktionalisierung und ihre Verwendung
|
JP2013505295A
(ja)
|
2009-09-22 |
2013-02-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を選択的に調節する化合物
|
NZ712378A
(en)
|
2009-10-14 |
2017-05-26 |
Xenon Pharmaceuticals Inc |
Synthetic methods for spiro-oxindole compounds
|
CA2778060A1
(en)
|
2009-10-21 |
2011-04-28 |
Boehringer Ingelheim International Gmbh |
Indazole and pyrazolopyridine compounds as ccr1 receptor antagonists
|
JP5542214B2
(ja)
|
2009-10-27 |
2014-07-09 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ccr1受容体アンタゴニストとしての複素環化合物
|
JP2013512954A
(ja)
*
|
2009-12-08 |
2013-04-18 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
置換インダゾール及びアザインダゾール化合物の生成に有効な中間体の合成方法
|
JP2013517271A
(ja)
|
2010-01-15 |
2013-05-16 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を調節する化合物
|
SG183126A1
(en)
|
2010-02-26 |
2012-09-27 |
Xenon Pharmaceuticals Inc |
Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
|
JP5746228B2
(ja)
|
2010-03-05 |
2015-07-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を選択的に調節するテトラゾール化合物
|
JP5871896B2
(ja)
|
2010-03-26 |
2016-03-01 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
B−rafキナーゼインヒビター
|
EP2552907B1
(de)
|
2010-03-26 |
2014-10-22 |
Boehringer Ingelheim International GmbH |
Pyridyltriazole
|
EP2563787B1
(de)
|
2010-04-30 |
2014-11-26 |
Boehringer Ingelheim International GmbH |
Azaindazolamidverbindungen als ccr1-rezeptor-antagonisten
|
US8846936B2
(en)
|
2010-07-22 |
2014-09-30 |
Boehringer Ingelheim International Gmbh |
Sulfonyl compounds which modulate the CB2 receptor
|
US9302991B2
(en)
*
|
2010-10-18 |
2016-04-05 |
Raqualia Pharma Inc. |
Arylamide derivatives as TTX-S blockers
|
WO2012052459A1
(en)
*
|
2010-10-21 |
2012-04-26 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
EP2630126B1
(de)
|
2010-10-21 |
2015-01-07 |
Glaxo Group Limited |
Pyrazolverbindungen gegen allergie-, immun- und entzündungserkrankungen
|
WO2012061926A1
(en)
*
|
2010-11-08 |
2012-05-18 |
Zalicus Pharmaceuticals Ltd. |
Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers
|
AR083987A1
(es)
|
2010-12-01 |
2013-04-10 |
Bayer Cropscience Ag |
Amidas de acido pirazolcarboxilico utiles para la reduccion de la contaminacion de micotoxina en las plantas
|
US8710055B2
(en)
|
2010-12-21 |
2014-04-29 |
Boehringer Ingelheim International Gmbh |
Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors
|
JP5684406B2
(ja)
|
2010-12-23 |
2015-03-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ccr1受容体アンタゴニストとしてのピラゾロピペリジン化合物
|
MX347952B
(es)
|
2011-05-13 |
2017-05-19 |
Array Biopharma Inc |
Compuestos de pirrolidinil urea y pirrolidinil tiourea como inhibidores de cinasa trka.
|
WO2012177263A1
(en)
|
2011-06-24 |
2012-12-27 |
Intra-Cellular Therapies, Inc. |
Compounds and methods of prophylaxis and treatment regarding nictonic receptor antagonists
|
DE102011055815A1
(de)
|
2011-11-29 |
2013-05-29 |
Aicuris Gmbh & Co. Kg |
Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung
|
WO2013138613A1
(en)
|
2012-03-16 |
2013-09-19 |
Axikin Pharmaceuticals, Inc. |
3,5-diaminopyrazole kinase inhibitors
|
JP2015516976A
(ja)
*
|
2012-04-17 |
2015-06-18 |
ギリアード サイエンシーズ, インコーポレイテッド |
抗ウイルス処置のための化合物および方法
|
KR102067235B1
(ko)
*
|
2012-04-25 |
2020-01-16 |
라퀄리아 파마 인코포레이티드 |
Ttx-s 차단제로서 아미드 유도체
|
DE102012016908A1
(de)
|
2012-08-17 |
2014-02-20 |
Aicuris Gmbh & Co. Kg |
Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung
|
US10092574B2
(en)
|
2012-09-26 |
2018-10-09 |
Valorisation-Recherche, Limited Partnership |
Inhibitors of polynucleotide repeat-associated RNA foci and uses thereof
|
CN103772284B
(zh)
*
|
2012-10-23 |
2015-08-12 |
沈阳感光化工研究院 |
一种4,5-二氨基-1-(2-羟乙基)吡唑硫酸盐的制备方法
|
CN102993097A
(zh)
*
|
2012-11-09 |
2013-03-27 |
贵州大学 |
吡唑酰胺类化合物及其应用
|
US9828360B2
(en)
|
2012-11-13 |
2017-11-28 |
Array Biopharma Inc. |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
WO2014078408A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
US9969694B2
(en)
|
2012-11-13 |
2018-05-15 |
Array Biopharma Inc. |
N-(arylalkyl)-N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
US9790178B2
(en)
|
2012-11-13 |
2017-10-17 |
Array Biopharma Inc. |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
WO2014078328A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
N-bicyclic aryl,n'-pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
AU2013344886B2
(en)
|
2012-11-13 |
2017-06-29 |
Array Biopharma Inc. |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain
|
WO2014078322A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
BR112015010875B1
(pt)
|
2012-11-13 |
2022-05-03 |
Array Biopharma Inc |
Compostos de n-pirrolidinil, n-pirazolil-ureia, tioureia, guanidina e cianoguanidina como inibidores de trka quinase, sua composição farmacêutica, seu uso e seu processo para preparação
|
US9790210B2
(en)
|
2012-11-13 |
2017-10-17 |
Array Biopharma Inc. |
N-(monocyclic aryl),N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
WO2014078417A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
MX2015008919A
(es)
|
2013-01-10 |
2015-10-22 |
Gruenenthal Gmbh |
Carboxamidas basadas en pirazolilo i como inhibidores del canal de calcio activado por liberacion de calcio (crac).
|
AU2014204977A1
(en)
|
2013-01-10 |
2015-08-20 |
Grunenthal Gmbh |
Pyrazolyl-based carboxamides II as CRAC channel inhibitors
|
EP2803668A1
(de)
|
2013-05-17 |
2014-11-19 |
Boehringer Ingelheim International Gmbh |
Neuartige (Cyano-dimethyl-methyl)-isoxazole und -[1,3,4]-thiadiazole
|
TWI636047B
(zh)
|
2013-08-14 |
2018-09-21 |
英商卡爾維斯塔製藥有限公司 |
雜環衍生物
|
NZ631142A
(en)
|
2013-09-18 |
2016-03-31 |
Axikin Pharmaceuticals Inc |
Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
|
CA2923503A1
(en)
*
|
2013-09-25 |
2015-04-02 |
Valorisation-Recherche |
Inhibitors of polynucleotide repeat-associated rna foci and uses thereof
|
US10835533B2
(en)
|
2014-05-15 |
2020-11-17 |
Array Biopharma Inc. |
1 -((3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl)urea as a TrkA kinase inhibitor
|
EP3152199B1
(de)
|
2014-06-03 |
2018-08-15 |
Idorsia Pharmaceuticals Ltd |
Pyrazol- verbindungen und ihre verwendung als t-typ calciumkanalblocker
|
EP3193609A4
(de)
*
|
2014-09-10 |
2018-02-28 |
Epizyme, Inc. |
Substituierte pyrrolidin-carboxamid-verbindungen
|
WO2016041892A1
(en)
|
2014-09-15 |
2016-03-24 |
Actelion Pharmaceuticals Ltd |
Triazole compounds as t-type calcium channel blockers
|
CN104402819B
(zh)
*
|
2014-09-22 |
2016-08-24 |
安徽农业大学 |
一类双吡唑酰胺衍生物的制备及其在治理水稻黑条矮缩病中的应用
|
GB201421085D0
(en)
|
2014-11-27 |
2015-01-14 |
Kalvista Pharmaceuticals Ltd |
New enzyme inhibitors
|
GB201421083D0
(en)
|
2014-11-27 |
2015-01-14 |
Kalvista Pharmaceuticals Ltd |
Enzyme inhibitors
|
ES2805528T3
(es)
|
2014-12-23 |
2021-02-12 |
Sma Therapeutics Inc |
Inhibidores de 3,5-diaminopirazol quinasa
|
TW201636017A
(zh)
|
2015-02-05 |
2016-10-16 |
梯瓦製藥國際有限責任公司 |
以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法
|
WO2016202758A1
(en)
|
2015-06-18 |
2016-12-22 |
Bayer Pharma Aktiengesellschaft |
Substituted 2-(1h-pyrazol-1-yl)-1h-benzimidazole compounds
|
WO2016202756A1
(en)
|
2015-06-18 |
2016-12-22 |
Bayer Pharma Aktiengesellschaft |
Substituted 2-(1h-pyrazol-1-yl)-1h-benzimidazole compounds
|
WO2016202935A1
(en)
|
2015-06-19 |
2016-12-22 |
Bayer Pharma Aktiengesellschaft |
Glucose transport inhibitors
|
DK3356345T3
(da)
*
|
2015-09-30 |
2024-02-12 |
Max Planck Gesellschaft |
Heteroaryl-derivater som sepiapterin-reduktase-inhibitorer
|
WO2017063966A1
(en)
|
2015-10-13 |
2017-04-20 |
Bayer Pharma Aktiengesellschaft |
Substituted 2-(1h-pyrazol-1-yl)-benzothiazole compounds
|
JP6572392B2
(ja)
|
2015-12-18 |
2019-09-11 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
電位作動型ナトリウムチャネルにおいて選択的活性を有する、ヒドロキシアルキルアミンおよびヒドロキシシクロアルキルアミンで置換されたジアミン−アリールスルホンアミド化合物
|
US10882841B2
(en)
|
2016-03-01 |
2021-01-05 |
University Of Maryland, Baltimore |
Wnt signaling pathway inhibitors for treatments of disease
|
HUE049918T2
(hu)
|
2016-05-31 |
2020-11-30 |
Kalvista Pharmaceuticals Ltd |
Pirazol-származékok mint plazma kallikrein inhibitorok
|
GB201609607D0
(en)
|
2016-06-01 |
2016-07-13 |
Kalvista Pharmaceuticals Ltd |
Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts
|
GB201609603D0
(en)
|
2016-06-01 |
2016-07-13 |
Kalvista Pharmaceuticals Ltd |
Polymorphs of N-[(6-cyano-2-fluoro-3-methoxyphenyl)Methyl]-3-(methoxymethyl)-1-({4-[(2-ox opyridin-1-YL)Methyl]phenyl}methyl)pyrazole-4-carboxamide
|
AU2017378487B2
(en)
|
2016-12-15 |
2022-03-31 |
The Regents Of The University Of California |
Compositions and methods for treating cancer
|
UA124977C2
(uk)
|
2016-12-16 |
2021-12-22 |
Ідорсія Фармасьютікалз Лтд |
Фармацевтична комбінація, яка містить блокатор кальцієвих каналів т-типу
|
TWI795381B
(zh)
|
2016-12-21 |
2023-03-11 |
比利時商健生藥品公司 |
作為malt1抑制劑之吡唑衍生物
|
CN110225781B
(zh)
*
|
2017-01-09 |
2022-05-17 |
辉诺生物医药科技(杭州)有限公司 |
噻唑衍生物及其应用
|
MX2019009242A
(es)
|
2017-02-06 |
2019-09-13 |
Idorsia Pharmaceuticals Ltd |
Un proceso novedoso para la sintesis de 1-aril-1-trifluoro-metil-c iclopropanos.
|
US11491150B2
(en)
|
2017-05-22 |
2022-11-08 |
Intra-Cellular Therapies, Inc. |
Organic compounds
|
LT3716952T
(lt)
|
2017-11-29 |
2022-04-11 |
Kalvista Pharmaceuticals Limited |
Vaisto formos, apimančios plazmos kalikreino inhibitorių
|
GB201719881D0
(en)
|
2017-11-29 |
2018-01-10 |
Kalvista Pharmaceuticals Ltd |
Solid forms of plasma kallikrein inhibitor and salts thereof
|
WO2019243965A1
(en)
|
2018-06-18 |
2019-12-26 |
Janssen Pharmaceutica Nv |
Pyrazole derivatives as malt1 inhibitors
|
JP7296408B2
(ja)
|
2018-06-18 |
2023-06-22 |
ヤンセン ファーマシューティカ エヌ.ベー. |
Malt1阻害剤としてのピラゾール誘導体
|
WO2020117626A1
(en)
|
2018-12-05 |
2020-06-11 |
Merck Sharp & Dohme Corp. |
4-amino or 4-alkoxy-substituted aryl sulfonamide compounds with selective activity in voltage-gated sodium channels
|
WO2021028645A1
(en)
|
2019-08-09 |
2021-02-18 |
Kalvista Pharmaceuticals Limited |
Plasma kallikrein inhibitors
|
CN114044754A
(zh)
*
|
2021-11-23 |
2022-02-15 |
贵州大学 |
一类5-三氟甲基-4-吡唑衍生物的制备方法及其在抑制肿瘤细胞上的应用
|