IL157340A0 - Novel succinate salt of o-desmethyl-venlafaxine - Google Patents
Novel succinate salt of o-desmethyl-venlafaxineInfo
- Publication number
- IL157340A0 IL157340A0 IL15734002A IL15734002A IL157340A0 IL 157340 A0 IL157340 A0 IL 157340A0 IL 15734002 A IL15734002 A IL 15734002A IL 15734002 A IL15734002 A IL 15734002A IL 157340 A0 IL157340 A0 IL 157340A0
- Authority
- IL
- Israel
- Prior art keywords
- desmethyl
- venlafaxine
- succinate salt
- novel succinate
- novel
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/10—Succinic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26821401P | 2001-02-12 | 2001-02-12 | |
US29796301P | 2001-06-13 | 2001-06-13 | |
PCT/US2002/004103 WO2002064543A2 (en) | 2001-02-12 | 2002-02-11 | Novel succinate salt of o-desmethyl-venlafaxine |
Publications (1)
Publication Number | Publication Date |
---|---|
IL157340A0 true IL157340A0 (en) | 2004-02-19 |
Family
ID=26952945
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15734002A IL157340A0 (en) | 2001-02-12 | 2002-02-11 | Novel succinate salt of o-desmethyl-venlafaxine |
IL157340A IL157340A (en) | 2001-02-12 | 2003-08-11 | O salts - Desmethyl - and nalfaxine succinate and the pharmaceutical compositions containing them |
IL200255A IL200255A (en) | 2001-02-12 | 2009-08-05 | Method of preparing o-desmethyl-venlafaxine |
IL209444A IL209444A (en) | 2001-02-12 | 2010-11-18 | Uses of O-Desmethyl-Venelfaxine Crystalline Succin |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL157340A IL157340A (en) | 2001-02-12 | 2003-08-11 | O salts - Desmethyl - and nalfaxine succinate and the pharmaceutical compositions containing them |
IL200255A IL200255A (en) | 2001-02-12 | 2009-08-05 | Method of preparing o-desmethyl-venlafaxine |
IL209444A IL209444A (en) | 2001-02-12 | 2010-11-18 | Uses of O-Desmethyl-Venelfaxine Crystalline Succin |
Country Status (31)
Country | Link |
---|---|
US (5) | US6673838B2 (de) |
EP (3) | EP2319826A1 (de) |
JP (1) | JP4220243B2 (de) |
KR (1) | KR100875610B1 (de) |
CN (2) | CN100567253C (de) |
AR (2) | AR032671A1 (de) |
AT (1) | ATE369330T1 (de) |
AU (1) | AU2002250058B2 (de) |
BR (1) | BR0207157A (de) |
CA (2) | CA2436668C (de) |
CY (1) | CY1106952T1 (de) |
DE (1) | DE60221642T3 (de) |
DK (1) | DK1360169T3 (de) |
EA (1) | EA011451B1 (de) |
ES (1) | ES2290281T5 (de) |
HK (1) | HK1057885A1 (de) |
HN (1) | HN2002000030A (de) |
HU (1) | HUP0303128A3 (de) |
IL (4) | IL157340A0 (de) |
MX (1) | MXPA03007043A (de) |
NO (1) | NO328807B1 (de) |
NZ (1) | NZ539791A (de) |
PA (1) | PA8539901A1 (de) |
PE (1) | PE20020877A1 (de) |
PL (2) | PL211788B1 (de) |
PT (1) | PT1360169E (de) |
SI (1) | SI1360169T1 (de) |
TW (1) | TWI318201B (de) |
UY (1) | UY27175A1 (de) |
WO (1) | WO2002064543A2 (de) |
ZA (1) | ZA200307116B (de) |
Families Citing this family (114)
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BR9914826A (pt) | 1998-10-30 | 2001-11-06 | Ajinomoto Kk | Processo de cristalização de cristais de éster metìlico de n- [n-(3,3-dimetilbutil)-l-alfa-aspartil] -l-fenilalanina |
US6342533B1 (en) * | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
NZ514612A (en) * | 1999-04-06 | 2004-01-30 | Sepracor Inc | Derivatives of venlafaxine and methods of preparing and using the same |
EP2319826A1 (de) * | 2001-02-12 | 2011-05-11 | Wyeth LLC | O-Desmethyl-Venlafaxine Succinat Salz |
US20050244498A1 (en) * | 2001-09-14 | 2005-11-03 | Biovail Laboratories, Inc. | Modified-release compositions of at least one form of venlafaxine |
UA80543C2 (en) | 2001-12-04 | 2007-10-10 | Wyeth Corp | Method for the preparation of o-desmethylvenlafaxine |
WO2003082261A1 (en) * | 2002-03-28 | 2003-10-09 | Synthon B.V. | Extended release venlafaxine formulations |
EP1519720A4 (de) * | 2002-06-10 | 2010-02-10 | Wyeth Corp | Neues format-salz von o-desmethyl-venlafaxin |
CN1678322A (zh) * | 2002-08-29 | 2005-10-05 | 阿瑞科诺沃治疗有限公司 | (4-(2-氟苯基)-6-甲基-2-(1-哌嗪基)噻吩并[2,3-d]嘧啶的新治疗用途 |
US7345096B2 (en) | 2002-10-15 | 2008-03-18 | Wyeth | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
PT1628685E (pt) | 2003-04-25 | 2011-03-16 | Gilead Sciences Inc | Análogos de fosfonatos antivirais |
JP2004359665A (ja) * | 2003-05-30 | 2004-12-24 | Rohm & Haas Co | 生体利用性増強剤を含有する治療組成物 |
US7531543B2 (en) | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
US7491723B2 (en) | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
US7524846B2 (en) | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
US7550485B2 (en) | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
US7365076B2 (en) | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
US7402698B2 (en) | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
CA2554559A1 (en) * | 2004-02-06 | 2005-08-25 | Wyeth | Multiparticulate o-desmethylvenlafaxine salts and uses thereof |
US7517899B2 (en) | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US7414052B2 (en) | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
US7439280B2 (en) * | 2004-04-06 | 2008-10-21 | Basf Corporation | Lignocellulosic composite material and method for preparing the same |
EP1773322A1 (de) * | 2004-07-22 | 2007-04-18 | Wyeth | Verfahren zur behandlung von erkrankungen und zuständen des nervensystems |
AU2005266994A1 (en) * | 2004-07-22 | 2006-02-02 | Wyeth | Method for treating nervous system disorders and conditions |
JP2008507551A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系疾患および病態の治療方法 |
RS51799B (en) | 2004-07-27 | 2011-12-31 | Gilead Sciences Inc. | NUCLEOSIDE-PHOSPHONATE CONJUGATES AS HIV AGENTS |
US20060228413A1 (en) * | 2005-02-28 | 2006-10-12 | Penwest Pharmaceuticals Co. | Controlled release venlafaxine formulations |
WO2006104791A1 (en) * | 2005-03-31 | 2006-10-05 | Wyeth | O-desmethylvenlafaxine and bazedoxifene combination product and uses thereof |
CN1955159B (zh) | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
MX2008000249A (es) * | 2005-07-06 | 2008-03-18 | Sepracor Inc | Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos. |
PE20070247A1 (es) * | 2005-07-15 | 2007-04-11 | Wyeth Corp | Derivados dimetilamino como agentes inhibidores de la recaptacion doble de serotonina y norepinefrina con alta selectividad |
US7687520B2 (en) | 2005-07-15 | 2010-03-30 | Wyeth Llc | Serotonin and norepinephrine reuptake inhibitors and uses thereof |
US7595340B2 (en) | 2005-07-15 | 2009-09-29 | Wyeth | Serotonin and norepinephrine reuptake inhibitor and uses thereof |
JP2009502798A (ja) * | 2005-07-21 | 2009-01-29 | ワイス | 神経系障害および状態の処置方法 |
GT200600396A (es) * | 2005-09-07 | 2007-04-23 | Dispositivos para la aplicacion de medicamentos transdermicos conteniendo o-desmetil venlafaxina (odv) o sus sales | |
GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales | |
CN1332946C (zh) * | 2005-10-21 | 2007-08-22 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 作用于中枢神经系统的前药 |
SI1954669T1 (sl) * | 2005-12-01 | 2016-01-29 | Auspex Pharmaceuticals, Inc. | Substituirani fenetilamini s serotoninergično in / ali noradrenalinsko aktivnostjo |
BRPI0619449A2 (pt) * | 2005-12-05 | 2011-03-29 | Wyeth Corp | processo para a sìntese estereosseletiva de uma (4s ou 4r)-4-benzil-3-[2r ou 2s]-(1-hidroxicicloexil)-(metoxifenil) acetil]-1,3-oxazolidin-2-ona e de um enantiÈmero de uma 2-fenil-2-(1-hidroxicicloalquil) etilamina ou seu sal e compostos |
WO2007071404A1 (en) | 2005-12-20 | 2007-06-28 | Synthon B.V. | Process for making desvenlafaxine |
JP2008546718A (ja) | 2006-04-17 | 2008-12-25 | テバ ファーマシューティカル インダストリーズ リミティド | 実質的に純粋なo−デスメチルベンラファキシン及びその調製方法。 |
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CN101442994B (zh) * | 2006-05-16 | 2013-03-06 | 吉里德科学公司 | 用于治疗恶性血液病的方法和组合物 |
US20090069601A1 (en) * | 2006-07-26 | 2009-03-12 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
JP4763788B2 (ja) * | 2006-07-26 | 2011-08-31 | テバ ファーマシューティカル インダストリーズ リミティド | O−デスメチルベンラファキシンの合成方法 |
EP1934167A2 (de) * | 2006-07-26 | 2008-06-25 | Teva Pharmaceutical Industries Ltd. | Verfahren zur synthese von o-desmethylvenlafaxin |
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US20090137846A1 (en) * | 2006-07-26 | 2009-05-28 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-Desmethylvenlafaxine |
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US20100063160A1 (en) * | 2006-10-18 | 2010-03-11 | Merck Development Centre Private Limited | Polymorphs of o-desmethyl venlafaxine succinate |
US20080261895A1 (en) * | 2006-10-25 | 2008-10-23 | Wyeth | Isolated hydroxy and n-oxide metabolites and derivatives of O-desmethylvenlafaxine and methods of treatment |
MX2009006528A (es) * | 2006-12-21 | 2009-06-26 | Pfizer Prod Inc | Sal de succinato de la 2-((4-(1-metil-4-(piridin-4-il)-1h-pirazol- 3-il)fenoxi)metil)quinolina. |
WO2009027766A2 (en) * | 2006-12-22 | 2009-03-05 | Medichem, S.A. | New crystalline solid forms of o-desvenlafaxine base |
US7820716B2 (en) * | 2007-01-08 | 2010-10-26 | Mai De Ltd | Crystalline polymorphs of desvenlafaxine succinate and their preparations |
AR064987A1 (es) * | 2007-01-22 | 2009-05-06 | Medichem Sa | Proceso mejorado para sintetizar desvenlafaxina como base libre y sales o solvatos de la misma |
CA2672808A1 (en) * | 2007-01-31 | 2008-08-07 | Generics [Uk] Limited | Process for the preparation of o-desmethyl venlafaxine |
CN101663263A (zh) * | 2007-02-21 | 2010-03-03 | 塞普拉柯公司 | 包含(-)-o-去甲基文拉法辛的固体形式及其用途 |
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