MX367362B - Nuevas formas solidas de desvenlafaxina. - Google Patents
Nuevas formas solidas de desvenlafaxina.Info
- Publication number
- MX367362B MX367362B MX2016008646A MX2016008646A MX367362B MX 367362 B MX367362 B MX 367362B MX 2016008646 A MX2016008646 A MX 2016008646A MX 2016008646 A MX2016008646 A MX 2016008646A MX 367362 B MX367362 B MX 367362B
- Authority
- MX
- Mexico
- Prior art keywords
- desvenlafaxine
- solid forms
- desmethylvenlafaxine
- menopause
- polymorphs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0018—Evaporation of components of the mixture to be separated
- B01D9/0022—Evaporation of components of the mixture to be separated by reducing pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/02—Laboratory benches or tables; Fittings therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
- C07C65/05—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0018—Evaporation of components of the mixture to be separated
- B01D9/0031—Evaporation of components of the mixture to be separated by heating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/004—Fractional crystallisation; Fractionating or rectifying columns
- B01D9/0045—Washing of crystals, e.g. in wash columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/02—Crystallisation from solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Clinical Laboratory Science (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invención se refiere a nuevas formas sólidas amorfas y cristalinas de desvenlafaxina, también llamado O-desmetilvenlafaxina o desmetilvenlafaxina, y a sus sales, solvatos, hidratos y polimorfos de las mismas, así como a su uso en la preparación de una composición farmacéutica útil para el tratamiento de la depresión y/o inhibidor selectivo de la reabsorción de serotonina y la norepinefrina así como a los trastornos vasomotores asociados a la menopausia.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2016008646A MX367362B (es) | 2016-06-29 | 2016-06-29 | Nuevas formas solidas de desvenlafaxina. |
CONC2017/0006492A CO2017006492A1 (es) | 2016-06-29 | 2017-06-27 | Nuevas formas sólidas de desvenlafaxina |
PE2017001162A PE20180025A1 (es) | 2016-06-29 | 2017-06-27 | Nuevas formas solidas de desvenlafaxina |
CA2972156A CA2972156C (en) | 2016-06-29 | 2017-06-28 | Solid forms of desvenlafaxine |
ES201730859A ES2648369B2 (es) | 2016-06-29 | 2017-06-28 | Nuevas formas sólidas de desvenlafaxina |
US15/636,818 US10207982B2 (en) | 2016-06-29 | 2017-06-29 | Solid forms of desvenlafaxine |
SV2017005474A SV2017005474A (es) | 2016-06-29 | 2017-06-29 | Nuevas formas sólidas de desvenlafaxina |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2016008646A MX367362B (es) | 2016-06-29 | 2016-06-29 | Nuevas formas solidas de desvenlafaxina. |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2016008646A MX2016008646A (es) | 2017-12-28 |
MX367362B true MX367362B (es) | 2019-08-16 |
Family
ID=60718150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016008646A MX367362B (es) | 2016-06-29 | 2016-06-29 | Nuevas formas solidas de desvenlafaxina. |
Country Status (7)
Country | Link |
---|---|
US (1) | US10207982B2 (es) |
CA (1) | CA2972156C (es) |
CO (1) | CO2017006492A1 (es) |
ES (1) | ES2648369B2 (es) |
MX (1) | MX367362B (es) |
PE (1) | PE20180025A1 (es) |
SV (1) | SV2017005474A (es) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
US6197828B1 (en) | 1998-12-01 | 2001-03-06 | Sepracor, Inc. | Derivatives of (+)-venlafaxine and methods of preparing and using the same |
CA2368083A1 (en) | 1999-04-06 | 2000-10-12 | Sepracor Inc. | Derivatives of venlafaxine and methods of preparing and using the same |
DK1360169T3 (da) | 2001-02-12 | 2007-11-26 | Wyeth Corp | Succinatsalt af O-desmethyl-venlafaxin |
WO2009053840A2 (en) | 2007-10-22 | 2009-04-30 | Actavis Group Ptc Ehf | Solid forms of (±)-o-desmethylvenlafaxine salts |
EP2085377A1 (en) | 2008-01-29 | 2009-08-05 | LEK Pharmaceuticals D.D. | Novel salts of O-desmethyl-venlafaxine |
EP2252573A2 (en) * | 2008-02-14 | 2010-11-24 | Egis Gyógyszergyár Nyilvánosan Müködö | New polymorph and amorphous forms of desvenlafaxine fumarate |
IN2008CH00818A (es) * | 2008-04-01 | 2009-10-09 | Actavis Group Ptc Ehf | |
EP2119695A1 (en) | 2008-05-16 | 2009-11-18 | Krka | Preparation of O-desmethylvenlafaxine salts |
WO2010008735A2 (en) * | 2008-06-16 | 2010-01-21 | Teva Pharmaceutical Industries Ltd. | Solid states of o-desmethylvenlaf axine salts |
CZ301503B6 (cs) | 2008-11-27 | 2010-03-24 | Zentiva, A. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
CZ302145B6 (cs) | 2009-07-15 | 2010-11-10 | Zentiva, K. S. | Zpusob prípravy desvenlafaxinu a jeho solí |
EP2340818A1 (en) | 2009-12-23 | 2011-07-06 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of venlafaxine and celecoxib |
US8481596B2 (en) * | 2011-06-08 | 2013-07-09 | Lupin Limited | Polymomorph of desvenlafaxine benzoate |
-
2016
- 2016-06-29 MX MX2016008646A patent/MX367362B/es active IP Right Grant
-
2017
- 2017-06-27 PE PE2017001162A patent/PE20180025A1/es unknown
- 2017-06-27 CO CONC2017/0006492A patent/CO2017006492A1/es unknown
- 2017-06-28 CA CA2972156A patent/CA2972156C/en active Active
- 2017-06-28 ES ES201730859A patent/ES2648369B2/es active Active
- 2017-06-29 SV SV2017005474A patent/SV2017005474A/es unknown
- 2017-06-29 US US15/636,818 patent/US10207982B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2972156A1 (en) | 2017-12-29 |
CO2017006492A1 (es) | 2018-01-05 |
US10207982B2 (en) | 2019-02-19 |
ES2648369A1 (es) | 2018-01-02 |
MX2016008646A (es) | 2017-12-28 |
PE20180025A1 (es) | 2018-01-09 |
US20180002273A1 (en) | 2018-01-04 |
ES2648369B2 (es) | 2018-06-08 |
SV2017005474A (es) | 2017-10-12 |
CA2972156C (en) | 2024-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GD | Licence granted | ||
FG | Grant or registration |