IL122290A0 - Lipid-nucleic acid complex its preparation and use - Google Patents

Lipid-nucleic acid complex its preparation and use

Info

Publication number
IL122290A0
IL122290A0 IL12229096A IL12229096A IL122290A0 IL 122290 A0 IL122290 A0 IL 122290A0 IL 12229096 A IL12229096 A IL 12229096A IL 12229096 A IL12229096 A IL 12229096A IL 122290 A0 IL122290 A0 IL 122290A0
Authority
IL
Israel
Prior art keywords
nucleic acid
lipid
particles
preparation
acid complex
Prior art date
Application number
IL12229096A
Other languages
English (en)
Original Assignee
Inex Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/485,458 external-priority patent/US5705385A/en
Priority claimed from US08/484,282 external-priority patent/US5981501A/en
Application filed by Inex Pharmaceuticals Corp filed Critical Inex Pharmaceuticals Corp
Publication of IL122290A0 publication Critical patent/IL122290A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
IL12229096A 1995-06-07 1996-06-06 Lipid-nucleic acid complex its preparation and use IL122290A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/485,458 US5705385A (en) 1995-06-07 1995-06-07 Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
US08/484,282 US5981501A (en) 1995-06-07 1995-06-07 Methods for encapsulating plasmids in lipid bilayers
PCT/US1996/009949 WO1996040964A2 (en) 1995-06-07 1996-06-06 Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer

Publications (1)

Publication Number Publication Date
IL122290A0 true IL122290A0 (en) 1998-04-05

Family

ID=27047938

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12229096A IL122290A0 (en) 1995-06-07 1996-06-06 Lipid-nucleic acid complex its preparation and use
IL122290A IL122290A (en) 1995-06-07 1997-11-25 Lipid-nucleic acid complex preparation and therapeutic compositions containing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL122290A IL122290A (en) 1995-06-07 1997-11-25 Lipid-nucleic acid complex preparation and therapeutic compositions containing same

Country Status (10)

Country Link
US (1) US5976567A (xx)
EP (2) EP0832271B8 (xx)
JP (2) JP4335310B2 (xx)
AT (1) ATE285477T1 (xx)
AU (1) AU723163B2 (xx)
CA (1) CA2222328C (xx)
DE (1) DE69634084T2 (xx)
ES (1) ES2231819T3 (xx)
IL (2) IL122290A0 (xx)
WO (1) WO1996040964A2 (xx)

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* Cited by examiner, † Cited by third party
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WO1996040964A3 (en) 1997-04-24
JP2009028046A (ja) 2009-02-12
EP0832271B8 (en) 2005-03-02
DE69634084T2 (de) 2005-12-08
WO1996040964A2 (en) 1996-12-19
IL122290A (en) 2006-12-31
CA2222328A1 (en) 1996-12-19
JP4335310B2 (ja) 2009-09-30
AU6330796A (en) 1996-12-30
EP0832271B1 (en) 2004-12-22
EP0832271A2 (en) 1998-04-01
EP1489184A1 (en) 2004-12-22
CA2222328C (en) 2012-01-10
JPH11507537A (ja) 1999-07-06
DE69634084D1 (de) 2005-01-27
AU723163B2 (en) 2000-08-17
ATE285477T1 (de) 2005-01-15
US5976567A (en) 1999-11-02

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