HUP0204074A3 - Humanized antibodies that sequester abetha peptide - Google Patents

Humanized antibodies that sequester abetha peptide

Info

Publication number
HUP0204074A3
HUP0204074A3 HU0204074A HUP0204074A HUP0204074A3 HU P0204074 A3 HUP0204074 A3 HU P0204074A3 HU 0204074 A HU0204074 A HU 0204074A HU P0204074 A HUP0204074 A HU P0204074A HU P0204074 A3 HUP0204074 A3 HU P0204074A3
Authority
HU
Hungary
Prior art keywords
abetha
sequester
peptide
humanized antibodies
humanized
Prior art date
Application number
HU0204074A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27391859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0204074(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUP0204074A2 publication Critical patent/HUP0204074A2/hu
Publication of HUP0204074A3 publication Critical patent/HUP0204074A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU0204074A 2000-02-24 2001-02-26 Humanized antibodies that sequester abetha peptide HUP0204074A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18460100P 2000-02-24 2000-02-24
US25449800P 2000-12-08 2000-12-08
US25446500P 2000-12-08 2000-12-08
PCT/US2001/006191 WO2001062801A2 (en) 2000-02-24 2001-02-26 Humanized antibodies that sequester amyloid beta peptide

Publications (2)

Publication Number Publication Date
HUP0204074A2 HUP0204074A2 (hu) 2003-03-28
HUP0204074A3 true HUP0204074A3 (en) 2004-07-28

Family

ID=27391859

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0204074A HUP0204074A3 (en) 2000-02-24 2001-02-26 Humanized antibodies that sequester abetha peptide
HU0800571A HU230768B1 (hu) 2000-02-24 2011-02-26 Aß peptidet kiválasztó humanizált ellenanyagok

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0800571A HU230768B1 (hu) 2000-02-24 2011-02-26 Aß peptidet kiválasztó humanizált ellenanyagok

Country Status (32)

Country Link
US (4) US7195761B2 (enExample)
EP (4) EP1257584B2 (enExample)
JP (2) JP4738696B2 (enExample)
KR (1) KR100767146B1 (enExample)
CN (3) CN1426423B (enExample)
AT (1) ATE279442T1 (enExample)
AU (1) AU4178601A (enExample)
BR (1) BRPI0108676B8 (enExample)
CA (1) CA2400559C (enExample)
CY (1) CY1118381T1 (enExample)
CZ (2) CZ304211B6 (enExample)
DE (2) DE1257584T1 (enExample)
DK (2) DK1481992T3 (enExample)
DZ (1) DZ3295A1 (enExample)
EA (1) EA006606B1 (enExample)
ES (2) ES2611427T3 (enExample)
HK (1) HK1048640B (enExample)
HR (2) HRP20020693B1 (enExample)
HU (2) HUP0204074A3 (enExample)
IL (3) IL151378A0 (enExample)
LT (1) LT1481992T (enExample)
MX (1) MXPA02008145A (enExample)
NO (2) NO329840B1 (enExample)
NZ (1) NZ520800A (enExample)
PL (2) PL210157B1 (enExample)
PT (2) PT1481992T (enExample)
SI (2) SI1257584T2 (enExample)
SK (2) SK288711B6 (enExample)
TR (1) TR200202799T3 (enExample)
UA (1) UA75881C2 (enExample)
WO (1) WO2001062801A2 (enExample)
ZA (1) ZA200206712B (enExample)

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* Cited by examiner, † Cited by third party
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