HRP20110882T1 - Ciklopenta [d] pirimidini kao inhibitori kinaze akt proteina - Google Patents

Ciklopenta [d] pirimidini kao inhibitori kinaze akt proteina Download PDF

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Publication number
HRP20110882T1
HRP20110882T1 HR20110882T HRP20110882T HRP20110882T1 HR P20110882 T1 HRP20110882 T1 HR P20110882T1 HR 20110882 T HR20110882 T HR 20110882T HR P20110882 T HRP20110882 T HR P20110882T HR P20110882 T1 HRP20110882 T1 HR P20110882T1
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HR
Croatia
Prior art keywords
methyl
cyclopenta
piperazin
dihydro
alkyl
Prior art date
Application number
HR20110882T
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English (en)
Croatian (hr)
Inventor
S. Mitchell Ian
F. Blake James
Xu Rui
C. Kallan Nicholas
Xiao Dengming
Lee Spencer Keith
R. Bencsik Josef
Liang Jun
Safina Brian
Li Jun
Chabot Christine
L. Banka Anna
M. Wallace Eli
T. Schlachter Stephen
Original Assignee
Array Biopharma
Genentech
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38686844&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20110882(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma, Genentech filed Critical Array Biopharma
Publication of HRP20110882T1 publication Critical patent/HRP20110882T1/hr

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
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  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gynecology & Obstetrics (AREA)
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  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Diabetes (AREA)
HR20110882T 2006-07-06 2011-11-28 Ciklopenta [d] pirimidini kao inhibitori kinaze akt proteina HRP20110882T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81876206P 2006-07-06 2006-07-06
PCT/US2007/072876 WO2008006032A1 (en) 2006-07-06 2007-07-05 Cyclopenta [d] pyrimidines as akt protein kinase inhibitors

Publications (1)

Publication Number Publication Date
HRP20110882T1 true HRP20110882T1 (hr) 2012-01-31

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ID=38686844

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Application Number Title Priority Date Filing Date
HR20110882T HRP20110882T1 (hr) 2006-07-06 2011-11-28 Ciklopenta [d] pirimidini kao inhibitori kinaze akt proteina

Country Status (32)

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US (3) US8003651B2 (ko)
EP (1) EP2049500B1 (ko)
JP (3) JP5268904B2 (ko)
KR (2) KR20150041164A (ko)
CN (2) CN101631778B (ko)
AR (1) AR061844A1 (ko)
AT (1) ATE523499T1 (ko)
AU (1) AU2007269052B2 (ko)
BR (1) BRPI0713555A2 (ko)
CA (1) CA2656618C (ko)
CL (1) CL2007001992A1 (ko)
CO (1) CO6160229A2 (ko)
CR (2) CR10601A (ko)
CY (1) CY1112142T1 (ko)
DK (1) DK2049500T3 (ko)
ES (1) ES2372955T3 (ko)
HK (1) HK1126758A1 (ko)
HR (1) HRP20110882T1 (ko)
IL (1) IL196051A (ko)
MA (1) MA30952B1 (ko)
MX (1) MX2008016203A (ko)
MY (1) MY147628A (ko)
NO (1) NO20090580L (ko)
NZ (1) NZ573979A (ko)
PL (1) PL2049500T3 (ko)
PT (1) PT2049500E (ko)
RS (1) RS52210B (ko)
RU (1) RU2481336C2 (ko)
SI (1) SI2049500T1 (ko)
TW (1) TWI428335B (ko)
UA (1) UA99597C2 (ko)
WO (1) WO2008006032A1 (ko)

Families Citing this family (44)

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Publication number Priority date Publication date Assignee Title
JP5268904B2 (ja) 2006-07-06 2013-08-21 アレイ バイオファーマ、インコーポレイテッド Ａｋｔプロテインキナーゼ阻害剤としてのシクロペンタ［ｄ］ピリミジン
SI2054418T1 (sl) * 2006-07-06 2012-02-29 Array Biopharma Inc Dihidrotieno pirimidini kot AKT protein kinazni inhibitorji
AU2014201211B2 (en) * 2006-07-06 2016-04-14 Array Biopharma Inc. Hydroxylated and methoxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
US8063050B2 (en) * 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
ATE493418T1 (de) 2006-07-06 2011-01-15 Array Biopharma Inc Dihydrofuropyrimidine als akt- proteinkinaseinhibitoren
UA95641C2 (en) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Hydroxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors
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