IL144103A0 - Antiviral method using mek inhibitors - Google Patents

Antiviral method using mek inhibitors

Info

Publication number
IL144103A0
IL144103A0 IL14410399A IL14410399A IL144103A0 IL 144103 A0 IL144103 A0 IL 144103A0 IL 14410399 A IL14410399 A IL 14410399A IL 14410399 A IL14410399 A IL 14410399A IL 144103 A0 IL144103 A0 IL 144103A0
Authority
IL
Israel
Prior art keywords
mek inhibitors
antiviral method
antiviral
mek
inhibitors
Prior art date
Application number
IL14410399A
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL144103A0 publication Critical patent/IL144103A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL14410399A 1999-01-07 1999-12-21 Antiviral method using mek inhibitors IL144103A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11502699P 1999-01-07 1999-01-07
PCT/US1999/030484 WO2000040237A1 (en) 1999-01-07 1999-12-21 Antiviral method using mek inhibitors

Publications (1)

Publication Number Publication Date
IL144103A0 true IL144103A0 (en) 2002-05-23

Family

ID=22358895

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14410399A IL144103A0 (en) 1999-01-07 1999-12-21 Antiviral method using mek inhibitors

Country Status (8)

Country Link
EP (1) EP1140067A1 (en)
JP (1) JP2002534381A (en)
AU (1) AU2203800A (en)
CA (1) CA2358438A1 (en)
HU (1) HUP0104933A3 (en)
IL (1) IL144103A0 (en)
WO (1) WO2000040237A1 (en)
ZA (1) ZA200104000B (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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RU2238264C2 (en) 1999-02-24 2004-10-20 Ф.Хоффманн-Ля Рош Аг Derivatives of benzene or pyridine and pharmaceutical composition based on thereof
DE10017480A1 (en) * 2000-04-07 2001-10-11 Transmit Technologietransfer Use of substances that act as MEK inhibitors for the manufacture of a medicament against DNA and RNA viruses
EP1301472B1 (en) 2000-07-19 2014-03-26 Warner-Lambert Company LLC Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids
EP1201765A3 (en) * 2000-10-16 2003-08-27 Axxima Pharmaceuticals Aktiengesellschaft Cellular kinases involved in cytomegalovirus infection and their inhibition
WO2002069960A2 (en) * 2001-03-06 2002-09-12 Axxima Pharmaceuticals Ag Use of mek inhibitors for treating inflammation and virus induced hemorrhagic shock
IL149462A0 (en) 2001-05-09 2002-11-10 Warner Lambert Co Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor
DE10138912A1 (en) * 2001-08-08 2003-02-27 Medinnova Ges Med Innovationen Use of active substances for the prophylaxis and / or therapy of viral diseases as well as test system for finding such active substances
US7235537B2 (en) 2002-03-13 2007-06-26 Array Biopharma, Inc. N3 alkylated benzimidazole derivatives as MEK inhibitors
ES2335276T3 (en) 2002-03-13 2010-03-24 Array Biopharma, Inc. DERIVATIVES OF BENCIMIDAZOL RENTED N3 AS INHIBITORS OF MEK.
DOP2003000641A (en) * 2002-05-10 2003-11-15 Pfizer INHIBITORS OF RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUSES AND COMPOSITIONS AND TREATMENT USED
US7538120B2 (en) 2003-09-03 2009-05-26 Array Biopharma Inc. Method of treating inflammatory diseases
US7144907B2 (en) 2003-09-03 2006-12-05 Array Biopharma Inc. Heterocyclic inhibitors of MEK and methods of use thereof
RU2352558C2 (en) 2003-10-21 2009-04-20 Уорнер-Ламберт Компани Ллс Polymorphic form of n-[(r)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide
US7732616B2 (en) 2003-11-19 2010-06-08 Array Biopharma Inc. Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof
WO2005051301A2 (en) 2003-11-19 2005-06-09 Array Biopharma Inc. Heterocyclic inhibitors of mek and methods of use thereof
US7517994B2 (en) 2003-11-19 2009-04-14 Array Biopharma Inc. Heterocyclic inhibitors of MEK and methods of use thereof
BRPI0416852A (en) 2003-11-21 2007-02-27 Array Biopharma Inc akt kinase inhibitors
DK1761528T3 (en) 2004-06-11 2008-05-05 Japan Tobacco Inc 5-Amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido [2,3-d] pyrimidine derivatives and related compounds for the treatment of cancer
US7378423B2 (en) 2004-06-11 2008-05-27 Japan Tobacco Inc. Pyrimidine compound and medical use thereof
SE0401969D0 (en) * 2004-08-02 2004-08-02 Astrazeneca Ab Piperidine derivatives
CN101626767A (en) 2005-05-18 2010-01-13 阵列生物制药公司 The heterocycle inhibitor of MEK and using method thereof
DK1934174T3 (en) 2005-10-07 2011-08-01 Exelixis Inc Acetidines as MEK inhibitors for the treatment of proliferative diseases
BRPI0713555A2 (en) 2006-07-06 2012-03-20 Array Biopharma, Inc. cyclopenta [d] pyrimidines as akt protein kinase inhibitors
JP5231410B2 (en) 2006-07-06 2013-07-10 アレイ バイオファーマ、インコーポレイテッド Dihydrofuropyrimidine as an AKT protein kinase inhibitor
US9303040B2 (en) 2006-07-06 2016-04-05 Array Biopharma Inc. Substituted piperazines as AKT inhibitors
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
US7999006B2 (en) 2006-12-14 2011-08-16 Exelixis, Inc. Methods of using MEK inhibitors
US8846683B2 (en) 2007-07-05 2014-09-30 Array Biopharma, Inc. Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
US8618097B2 (en) 2007-07-05 2013-12-31 Array Biopharma, Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
JP5542282B2 (en) 2007-07-05 2014-07-09 アレイ バイオファーマ、インコーポレイテッド Pyrimidylcyclopentane as an AKT protein kinase inhibitor
US8835434B2 (en) 2008-01-09 2014-09-16 Array Biopharma, Inc. Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors
ES2401685T3 (en) 2008-01-09 2013-04-23 Array Biopharma, Inc. Hydroxylated pyrimidyl cyclopentane as an AKT protein kinase inhibitor
WO2010051933A2 (en) 2008-11-10 2010-05-14 Bayer Schering Pharma Aktiengesellschaft Substituted sulphonamido phenoxybenzamides
CN102574782B (en) 2009-10-21 2014-10-08 拜耳知识产权有限责任公司 Substituted halophenoxybenzamide derivatives
JP2013508318A (en) 2009-10-21 2013-03-07 バイエル・ファルマ・アクチェンゲゼルシャフト Substituted benzosulfonamide derivatives
EP2491016A1 (en) 2009-10-21 2012-08-29 Bayer Pharma Aktiengesellschaft Substituted benzosulphonamides
EP2580190A4 (en) * 2010-06-11 2014-04-16 Goeran Wadell New antiviral compounds
CA2816188A1 (en) 2010-10-29 2012-05-03 Marion Hitchcock Substituted phenoxypyridines
EP2694073B1 (en) 2011-04-01 2018-08-08 Genentech, Inc. Combinations of akt and mek inhibitors for treating cancer
TR201802093T4 (en) 2011-04-01 2018-03-21 Genentech Inc Combination of act inhibitor compound and abiraterone for use in therapeutic therapies.
AU2013328824B2 (en) * 2012-10-08 2018-04-05 Atriva Therapeutics Gmbh MEK inhibitors in the treatment of virus diseases
PL2909188T3 (en) 2012-10-12 2018-08-31 Exelixis, Inc. Novel process for making compounds for use in the treatment of cancer
JP6863742B2 (en) 2013-09-11 2021-04-21 ジ・アドミニストレーターズ・オブ・ザ・チューレーン・エデュケーショナル・ファンド New anthranilamide and its use
PT3697405T (en) * 2017-10-17 2021-08-27 Atriva Therapeutics Gmbh Novel mek-inhibitor for the treatment of viral and bacterial infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420338B1 (en) * 1997-06-13 2002-07-16 New York University Medical Center Inhibition of the Src kinase family pathway as a method of treating HBV infection and hepatocellular carcinoma
BR9810385A (en) * 1997-07-01 2000-09-05 Warner Lambert Co Derivatives of benzoic acid 2- (4-bromine or 4-iodine phenylamino) and their use as mek inhibitors
AU757046B2 (en) * 1997-07-01 2003-01-30 Warner-Lambert Company 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors

Also Published As

Publication number Publication date
HUP0104933A3 (en) 2003-12-29
ZA200104000B (en) 2002-08-16
CA2358438A1 (en) 2000-07-13
HUP0104933A2 (en) 2002-04-29
WO2000040237A1 (en) 2000-07-13
EP1140067A1 (en) 2001-10-10
JP2002534381A (en) 2002-10-15
AU2203800A (en) 2000-07-24

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