HRP20110685T1 - Cjepivo od konjugata pneumokoknog polisaharida - Google Patents
Cjepivo od konjugata pneumokoknog polisaharida Download PDFInfo
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- HRP20110685T1 HRP20110685T1 HR20110685T HRP20110685T HRP20110685T1 HR P20110685 T1 HRP20110685 T1 HR P20110685T1 HR 20110685 T HR20110685 T HR 20110685T HR P20110685 T HRP20110685 T HR P20110685T HR P20110685 T1 HRP20110685 T1 HR P20110685T1
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- serotype
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- 108010060123 Conjugate Vaccines Proteins 0.000 title 1
- 229940031670 conjugate vaccine Drugs 0.000 title 1
- 150000004676 glycans Chemical class 0.000 title 1
- 229920001282 polysaccharide Polymers 0.000 title 1
- 239000005017 polysaccharide Substances 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 claims abstract 21
- 241000193998 Streptococcus pneumoniae Species 0.000 claims abstract 16
- 239000002775 capsule Substances 0.000 claims abstract 14
- 230000002163 immunogen Effects 0.000 claims abstract 14
- 208000015181 infectious disease Diseases 0.000 claims abstract 14
- 230000006806 disease prevention Effects 0.000 claims abstract 13
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims abstract 11
- 108010078791 Carrier Proteins Proteins 0.000 claims abstract 9
- 102000014914 Carrier Proteins Human genes 0.000 claims abstract 9
- 229960003983 diphtheria toxoid Drugs 0.000 claims abstract 9
- 239000000203 mixture Substances 0.000 claims abstract 4
- 229960000814 tetanus toxoid Drugs 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims 1
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 claims 1
- 241000606768 Haemophilus influenzae Species 0.000 claims 1
- 108700028353 OmpC Proteins 0.000 claims 1
- 101710188053 Protein D Proteins 0.000 claims 1
- 101710132893 Resolvase Proteins 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
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- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
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Abstract
Imunogeni pripravak bakterije Streptococcus pneumoniae koji sadrži 9 ili više, 10 ili više, 11 ili više, 13 ili više, ili 14 ili više saharida iz kapsule različitih serotipova bakterije S. pneumoniae konjugiranih s 2 ili više različitih proteina-nosača, gdje navedeni pripravak sadrži saharid iz kapsule serotipa 19F, konjugiran s difterijskim toksoidom (DT), no ne sadrži saharid iz kapsule serotipa 19A, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae. Patent sadrži još 12 patentnih zahtjeva.
Claims (13)
1. Imunogeni pripravak bakterije Streptococcus pneumoniae koji sadrži 9 ili više, 10 ili više, 11 ili više, 13 ili više, ili 14 ili više saharida iz kapsule različitih serotipova bakterije S. pneumoniae konjugiranih s 2 ili više različitih proteina-nosača, gdje navedeni pripravak sadrži saharid iz kapsule serotipa 19F, konjugiran s difterijskim toksoidom (DT), no ne sadrži saharid iz kapsule serotipa 19A, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
2. Imunogeni pripravak u skladu s patentnim zahtjevom 1, gdje je saharid iz kapsule serotipa 19F jedini saharid u pripravku konjugiran s difterijskim toksoidom (DT), naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
3. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje je saharid iz kapsule sarotipa 19F izravno konjugiran s proteinom-nosačem, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
4. Imunogeni pripravak u skladu s patentnim zahtjevom 1 ili 2, gdje je saharid iz kapsule sarotipa 19F konjugiran s proteinom-nosačem preko spojnice, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
5. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje je saharid iz serotipa 19F konjugiran s proteinom-nosačem ili sa spojnicom uz pomoć CDAP kemije, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
6. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje je omjer između proteina-nosača i saharida iz serotipa 19F između 5:1 i 1:5, 4:1 i 1:1 ili 2:1 i 1:1, ili 1,5:1 i 1,4:1 (težinski), naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
7. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje je prosječna veličina (primjerice u Mw) saharida iz serotipa 19F iznad 100 kDa, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
8. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje doza konjugata saharida iz serotipa 19F je između 1 i 10 µg, 1 i 5 µg, ili 1 i 3 µg saharida, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
9. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva koji sadrži 2, 3, 4, 5 ili 6 različitih proteina-nosača, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
10. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje se jedan ili više ili sve proteine-nosače bira iz skupine koju čine DT, CRM197, TT, Fragment C, dPly, PhtA, PhyB, PhtD, PhtE, PhtDE OmpC, PorS i Protein D iz bakterije Haemophilus influenzae, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
11. Imunogeni pripravak u skladu s bilo kojim od prethodnih patentnih zahtjeva, gdje pripravak sadrži saharid iz kapsule serotipa 18C konjugiran s TT, naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
12. Imunogeni pripravak u skladu s patentnim zahtjevom 11, gdje je saharid iz kapsule serotipa 18C jedini saharid u pripravku konjugiran s tetanusnim toksoidom (TT), naznačen time što je namijenjen upotrebi u liječenju ili sprječavanju bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
13. Upotreba imunogenog pripravka koji sadrži 9 ili više, 10 ili više, 11 ili više, 13 ili više, ili 14 ili više saharida iz kapsule različitih serotipova bakterije S. pneumoniae konjugiranih s 2 ili više različitih proteina-nosača, gdje navedeni pripravak sadrži saharid iz kapsule serotipa 19F, konjugiran s difterijskim toksoidom (DT), no ne sadrži saharid iz kapsule serotipa 19A, naznačena time što je navedeni pripravak namijenjen proizvodnji medikamenta za liječenje ili sprječavanje bolesti uzrokovanih infekcijom sojevima serotipa 19A bakterije Streptococcus pneumoniae.
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0526232A GB0526232D0 (en) | 2005-12-22 | 2005-12-22 | Vaccine |
GBGB0607088.2A GB0607088D0 (en) | 2006-04-07 | 2006-04-07 | Vaccine |
GB0607087A GB0607087D0 (en) | 2006-04-07 | 2006-04-07 | Vaccine |
GB0609902A GB0609902D0 (en) | 2006-05-18 | 2006-05-18 | Novel composition |
GBGB0620336.8A GB0620336D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
GB0620337A GB0620337D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
GB0620816A GB0620816D0 (en) | 2006-10-19 | 2006-10-19 | vaccine |
GB0620815A GB0620815D0 (en) | 2006-10-19 | 2006-10-19 | Vaccine |
PCT/GB2006/004634 WO2007068907A2 (en) | 2005-12-13 | 2006-12-12 | Vaccine compositions comprising a saponin adjuvant |
PCT/EP2006/069974 WO2007071707A2 (en) | 2005-12-22 | 2006-12-20 | Pneumococcal polysaccharide conjugate vaccine |
Publications (1)
Publication Number | Publication Date |
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HRP20110685T1 true HRP20110685T1 (hr) | 2011-10-31 |
Family
ID=39133667
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20110685T HRP20110685T1 (hr) | 2005-12-22 | 2011-09-23 | Cjepivo od konjugata pneumokoknog polisaharida |
HRP20161682TT HRP20161682T1 (hr) | 2005-12-22 | 2016-12-08 | Cjepivo koje sadrži konjugate polisaharida iz kapsule bakterije streptococcus pneumoniae |
HRP20161681TT HRP20161681T1 (hr) | 2005-12-22 | 2016-12-08 | Cjepivo protiv bakterije streptococcus pneumoniae |
HRP20190037TT HRP20190037T1 (hr) | 2005-12-22 | 2019-01-04 | Cjepivo na bazi konjugata pneumokoknih polisaharida |
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HRP20161681TT HRP20161681T1 (hr) | 2005-12-22 | 2016-12-08 | Cjepivo protiv bakterije streptococcus pneumoniae |
HRP20190037TT HRP20190037T1 (hr) | 2005-12-22 | 2019-01-04 | Cjepivo na bazi konjugata pneumokoknih polisaharida |
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