CY1118535T1 - Εμβολιο streptococcus pneumoniae - Google Patents
Εμβολιο streptococcus pneumoniaeInfo
- Publication number
- CY1118535T1 CY1118535T1 CY20171100077T CY171100077T CY1118535T1 CY 1118535 T1 CY1118535 T1 CY 1118535T1 CY 20171100077 T CY20171100077 T CY 20171100077T CY 171100077 T CY171100077 T CY 171100077T CY 1118535 T1 CY1118535 T1 CY 1118535T1
- Authority
- CY
- Cyprus
- Prior art keywords
- streptococcus pneumoniae
- capsule
- conjugated
- pneumoniae vaccine
- saccharide
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/385—Haptens or antigens, bound to carriers
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6415—Toxins or lectins, e.g. clostridial toxins or Pseudomonas exotoxins
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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- A—HUMAN NECESSITIES
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- A61K2039/6068—Other bacterial proteins, e.g. OMP
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- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
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- A61K2039/70—Multivalent vaccine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Η παρούσα εφεύρεση ανήκει στο πεδίο των εμβολίων συζευγμάτων σακχαριτών κάψας Streptococcus pneumoniae. Ειδικά, μια πολυσθενής ανοσογόνος σύνθεση Streptococcus pneumoniae παρέχεται που περιέχει 10 ή περισσότερους σακχαρίτες κάψας από διαφορετικούς οροτύπους S. pneumoniae που είναι συζευγμένοι με μια φέρουσα πρωτεΐνη, και περιέχει 3 ή περισσότερες διαφορετικές φέρουσες πρωτεΐνες, όπου η σύνθεση περιέχει σακχαρίτη κάψας ορότυπου 19F συζευγμένο με ανατοξίνη διφθερίτιδας (DT)• σακχαρίτη κάψας ορότυπου 18C συζευγμένο με ανατοξίνη τετάνου (ΤΤ)• σακχαρίτες κάψας ορότυπου 1, 4, 5, 6Β, 7F, 9V, 14 και 23F συζευγμένους με πρωτεΐνη D από Haemophilus influenzae.
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0526232A GB0526232D0 (en) | 2005-12-22 | 2005-12-22 | Vaccine |
GB0607087A GB0607087D0 (en) | 2006-04-07 | 2006-04-07 | Vaccine |
GBGB0607088.2A GB0607088D0 (en) | 2006-04-07 | 2006-04-07 | Vaccine |
GB0609902A GB0609902D0 (en) | 2006-05-18 | 2006-05-18 | Novel composition |
GB0620337A GB0620337D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
GBGB0620336.8A GB0620336D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
GB0620815A GB0620815D0 (en) | 2006-10-19 | 2006-10-19 | Vaccine |
GB0620816A GB0620816D0 (en) | 2006-10-19 | 2006-10-19 | vaccine |
PCT/GB2006/004634 WO2007068907A2 (en) | 2005-12-13 | 2006-12-12 | Vaccine compositions comprising a saponin adjuvant |
EP06830743A EP1962899B1 (en) | 2005-12-22 | 2006-12-20 | Pneumococcal polysaccharide conjugate vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118535T1 true CY1118535T1 (el) | 2017-07-12 |
Family
ID=39133667
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100993T CY1112677T1 (el) | 2005-12-22 | 2011-10-19 | Εμβολιο συζευγμενου πνευμονοκοκκικου πολυσακχαριδιου |
CY20151100528T CY1116407T1 (el) | 2005-12-22 | 2015-06-19 | Εμβολιο |
CY20161101312T CY1118345T1 (el) | 2005-12-22 | 2016-12-16 | Εμβολιο που περιλαμβανει προϊοντα συζευξης καψικου πολυσακχαριδιου streptococcus pneumoniae |
CY20171100077T CY1118535T1 (el) | 2005-12-22 | 2017-01-18 | Εμβολιο streptococcus pneumoniae |
CY20191100081T CY1121376T1 (el) | 2005-12-22 | 2019-01-21 | Εμβολιο προϊοντος συζευξης πνευμονιοκοκκικου πολυσακχαριδιου |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100993T CY1112677T1 (el) | 2005-12-22 | 2011-10-19 | Εμβολιο συζευγμενου πνευμονοκοκκικου πολυσακχαριδιου |
CY20151100528T CY1116407T1 (el) | 2005-12-22 | 2015-06-19 | Εμβολιο |
CY20161101312T CY1118345T1 (el) | 2005-12-22 | 2016-12-16 | Εμβολιο που περιλαμβανει προϊοντα συζευξης καψικου πολυσακχαριδιου streptococcus pneumoniae |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20191100081T CY1121376T1 (el) | 2005-12-22 | 2019-01-21 | Εμβολιο προϊοντος συζευξης πνευμονιοκοκκικου πολυσακχαριδιου |
Country Status (37)
Country | Link |
---|---|
US (10) | US20090017072A1 (el) |
EP (10) | EP1973564B1 (el) |
JP (7) | JP5579387B2 (el) |
KR (5) | KR101515078B1 (el) |
CN (6) | CN101378779B (el) |
AR (3) | AR058707A1 (el) |
AT (1) | ATE520415T1 (el) |
AU (4) | AU2006327036B2 (el) |
BR (3) | BRPI0620163B8 (el) |
CA (5) | CA2816182C (el) |
CL (1) | CL2013002106A1 (el) |
CR (2) | CR10119A (el) |
CY (5) | CY1112677T1 (el) |
DK (5) | DK2384765T3 (el) |
EA (3) | EA014649B1 (el) |
ES (4) | ES2630759T3 (el) |
HK (1) | HK1120230A1 (el) |
HR (4) | HRP20110685T1 (el) |
HU (3) | HUE032903T2 (el) |
IL (5) | IL191911A (el) |
JO (1) | JO2813B1 (el) |
LT (3) | LT2384765T (el) |
MA (3) | MA30065B1 (el) |
MX (2) | MX354843B (el) |
MY (4) | MY147495A (el) |
NO (4) | NO346529B1 (el) |
NZ (4) | NZ569077A (el) |
PE (2) | PE20071058A1 (el) |
PH (1) | PH12014502544A1 (el) |
PL (5) | PL2384765T3 (el) |
PT (5) | PT1968631E (el) |
SG (1) | SG168517A1 (el) |
SI (5) | SI1973564T1 (el) |
TR (1) | TR201900418T4 (el) |
TW (4) | TWI465248B (el) |
UA (2) | UA96934C2 (el) |
WO (3) | WO2007071707A2 (el) |
Families Citing this family (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU227893B1 (en) * | 2000-06-29 | 2012-05-29 | Glaxosmithkline Biolog Sa | Vaccine compositions |
ATE317267T1 (de) | 2000-11-07 | 2006-02-15 | Immunovaccine Technologies Inc | Impfstoffe mit erhöhter immunantwort und verfahren zur deren herstellung |
US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
IL308456A (en) | 2005-04-08 | 2024-01-01 | Wyeth Llc | A multivalent pneumomuroral protein-polysaccharide conjugate preparation |
PE20110072A1 (es) | 2005-06-27 | 2011-02-04 | Glaxosmithkline Biolog Sa | Composicion inmunogenica |
CA2816182C (en) | 2005-12-22 | 2018-02-20 | Glaxosmithkline Biologicals S.A. | Pneumococcal polysaccharide conjugate vaccine |
EP2081953A2 (en) * | 2006-08-17 | 2009-07-29 | The UAB Research Foundation | Immunogenic pcpa polypeptides and uses thereof |
EP2155244B1 (en) * | 2007-04-23 | 2017-03-22 | Serum Institute of India Private Limited | Antigenic polysaccharides and process for their preparation |
JP2010525035A (ja) | 2007-05-02 | 2010-07-22 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
KR101579947B1 (ko) * | 2007-06-26 | 2015-12-28 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 스트렙토코쿠스 뉴모니애 캡슐 다당류 컨쥬게이트를 포함하는 백신 |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
CN101827613A (zh) | 2007-09-27 | 2010-09-08 | 免疫疫苗技术有限公司 | 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用 |
PL2200642T3 (pl) | 2007-10-19 | 2012-09-28 | Novartis Ag | Preparaty szczepionek meningokokowych |
EP2252326A4 (en) * | 2008-02-01 | 2012-08-29 | Newcastle Innovation Ltd | VACCINE COMPOSITIONS |
CN102065889A (zh) * | 2008-04-16 | 2011-05-18 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
MX2010011412A (es) * | 2008-04-16 | 2010-11-12 | Glaxosmithkline Biolog Sa | Vacuna. |
US9125863B2 (en) * | 2008-05-22 | 2015-09-08 | Children's Medical Center Corporation | Synergistic immunogenic fusion protein-polysaccharide conjugate |
EP2296696B1 (en) | 2008-06-05 | 2014-08-27 | ImmunoVaccine Technologies Inc. | Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance |
GB0822633D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
CA2747340A1 (en) | 2008-12-17 | 2010-06-24 | Novartis Ag | Meningococcal vaccines including hemoglobin receptor |
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