DE69431624T2 - Impfstoff gegen mittelohrentzündung - Google Patents
Impfstoff gegen mittelohrentzündungInfo
- Publication number
- DE69431624T2 DE69431624T2 DE69431624T DE69431624T DE69431624T2 DE 69431624 T2 DE69431624 T2 DE 69431624T2 DE 69431624 T DE69431624 T DE 69431624T DE 69431624 T DE69431624 T DE 69431624T DE 69431624 T2 DE69431624 T2 DE 69431624T2
- Authority
- DE
- Germany
- Prior art keywords
- fimbrin
- ignition
- vaccine against
- dna coding
- against medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 102100035181 Plastin-1 Human genes 0.000 abstract 5
- 108010049148 plastin Proteins 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 241000606790 Haemophilus Species 0.000 abstract 1
- 206010033078 Otitis media Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6544293A | 1993-05-18 | 1993-05-18 | |
PCT/US1994/005477 WO1994026304A1 (en) | 1993-05-18 | 1994-05-12 | Otitis media vaccine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69431624D1 DE69431624D1 (de) | 2002-12-05 |
DE69431624T2 true DE69431624T2 (de) | 2003-07-10 |
Family
ID=22062752
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69431624T Expired - Fee Related DE69431624T2 (de) | 1993-05-18 | 1994-05-12 | Impfstoff gegen mittelohrentzündung |
Country Status (9)
Country | Link |
---|---|
US (3) | US5766608A (de) |
EP (2) | EP0699076B1 (de) |
JP (1) | JP3429313B2 (de) |
AT (1) | ATE226831T1 (de) |
DE (1) | DE69431624T2 (de) |
DK (1) | DK0699076T3 (de) |
ES (1) | ES2185658T3 (de) |
PT (1) | PT699076E (de) |
WO (1) | WO1994026304A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2185658T3 (es) | 1993-05-18 | 2003-05-01 | Univ Ohio State Res Found | Vacuna para la otitis media. |
JPH09500013A (ja) * | 1993-06-01 | 1997-01-07 | ライフ・テクノロジーズ・インコーポレイテッド | カチオン性脂質による遺伝子免疫 |
US5770213A (en) | 1994-05-05 | 1998-06-23 | American Cyanamid Company | Purified nontypable haemophilus influenzae P5 protein as a vaccine for nontypable haemophilus influenzae infection |
US5843464A (en) | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
GB9812613D0 (en) * | 1998-06-11 | 1998-08-12 | Smithkline Beecham Biolog | Vaccine |
AU772847B2 (en) * | 1998-11-12 | 2004-05-06 | Invitrogen Corporation | Transfection reagents |
SI1162999T1 (sl) | 1999-03-19 | 2007-04-30 | Glaxosmithkline Biolog Sa | Vakcina proti Streptococcus pneumoniae |
GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
GB0117762D0 (en) * | 2001-07-20 | 2001-09-12 | Glaxosmithkline Biolog Sa | Novel compounds |
ES2537737T3 (es) | 2002-08-02 | 2015-06-11 | Glaxosmithkline Biologicals S.A. | Composiciones de vacuna que comprenden lipooligosacáridos de inmunotipo L2 y/o L3 de Neisseria meningitidis de IgtB |
ATE352316T1 (de) | 2002-11-01 | 2007-02-15 | Glaxosmithkline Biolog Sa | Immunogene zusammensetzung |
US8574596B2 (en) | 2003-10-02 | 2013-11-05 | Glaxosmithkline Biologicals, S.A. | Pertussis antigens and use thereof in vaccination |
GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
EP2298794A3 (de) * | 2005-07-08 | 2011-04-06 | Nationwide Children's Hospital, Inc. | Chimärer Impfstoff gegen Haemophilus Influenzae induzierte Krankheiten |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
ES2707499T3 (es) | 2005-12-22 | 2019-04-03 | Glaxosmithkline Biologicals Sa | Vacuna de conjugado de polisacárido neumocócico |
KR101737464B1 (ko) | 2006-01-17 | 2017-05-18 | 아르네 포르스그렌 아베 | 표면 노출된 헤모필루스 인플루엔자 단백질 (단백질 E ― pE) |
RS54349B1 (en) | 2007-06-26 | 2016-02-29 | Glaxosmithkline Biologicals S.A. | VACCINE CONTAINING STREPTOCOCCUS PNEUMONIAE Capsular POLYSACCHARIDE CONJUGATES |
EP2250286A1 (de) * | 2008-02-15 | 2010-11-17 | Life Technologies Corporation | Verfahren und zusammensetzungen zum scheren von polymeren mittels ultraschallbehandlung |
GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
US20130011429A1 (en) | 2010-03-10 | 2013-01-10 | Jan Poolman | Immunogenic composition |
GB201103836D0 (en) | 2011-03-07 | 2011-04-20 | Glaxosmithkline Biolog Sa | Conjugation process |
EP2717909B1 (de) | 2011-06-04 | 2017-12-06 | Rochester General Hospital Research Institute | Zusammensetzungen und verfahren in zusammenhang mit p6 von haemophilus influenzae |
CA2904388C (en) | 2013-03-08 | 2023-09-26 | Research Institute At Nationwide Children's Hospital | Transcutaneous dosage formulation |
EP3169310A1 (de) | 2014-07-15 | 2017-05-24 | Life Technologies Corporation | Zusammensetzungen mit lipidaggregaten und verfahren zur effizienten bereitstellung von molekülen an zellen |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
IE20190084A3 (en) | 2017-05-30 | 2023-07-19 | Glaxosmithkline Biologicals Sa | Novel methods for manufacturing an adjuvant |
EP3717001A1 (de) | 2017-12-01 | 2020-10-07 | GlaxoSmithKline Biologicals S.A. | Saponinreinigung |
MX2021001479A (es) | 2018-08-07 | 2021-04-28 | Glaxosmithkline Biologicals Sa | Novedosos procesos y vacunas. |
EP3886901A1 (de) | 2018-11-29 | 2021-10-06 | GlaxoSmithKline Biologicals S.A. | Verfahren zur herstellung eines adjuvans |
CA3142300A1 (en) | 2019-06-05 | 2020-12-10 | Glaxosmithkline Biologicals Sa | Saponin purification |
GB202205833D0 (en) | 2022-04-21 | 2022-06-08 | Glaxosmithkline Biologicals Sa | Bacteriophage |
WO2024017827A1 (en) | 2022-07-19 | 2024-01-25 | Glaxosmithkline Biologicals Sa | Continuous process for vaccine production |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4888170A (en) * | 1981-10-22 | 1989-12-19 | Research Corporation | Vaccines obtained from antigenic gene products of recombinant genes |
DK219084D0 (da) * | 1984-05-02 | 1984-05-02 | Frederik Carl Peter Lindberg | Antigen |
US5110908A (en) * | 1986-12-31 | 1992-05-05 | Praxis Biologics, Inc. | Haemophilus influenzae peptides and proteins |
ES2185658T3 (es) | 1993-05-18 | 2003-05-01 | Univ Ohio State Res Found | Vacuna para la otitis media. |
-
1994
- 1994-05-12 ES ES94922428T patent/ES2185658T3/es not_active Expired - Lifetime
- 1994-05-12 WO PCT/US1994/005477 patent/WO1994026304A1/en active IP Right Grant
- 1994-05-12 DK DK94922428T patent/DK0699076T3/da active
- 1994-05-12 EP EP94922428A patent/EP0699076B1/de not_active Expired - Lifetime
- 1994-05-12 AT AT94922428T patent/ATE226831T1/de not_active IP Right Cessation
- 1994-05-12 JP JP52577994A patent/JP3429313B2/ja not_active Expired - Fee Related
- 1994-05-12 PT PT94922428T patent/PT699076E/pt unknown
- 1994-05-12 EP EP02023186A patent/EP1300156A3/de not_active Ceased
- 1994-05-12 DE DE69431624T patent/DE69431624T2/de not_active Expired - Fee Related
-
1995
- 1995-06-01 US US08/457,997 patent/US5766608A/en not_active Expired - Lifetime
- 1995-06-06 US US08/467,722 patent/US6030626A/en not_active Expired - Lifetime
-
1999
- 1999-11-29 US US09/451,184 patent/US6562349B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE226831T1 (de) | 2002-11-15 |
WO1994026304A1 (en) | 1994-11-24 |
US5766608A (en) | 1998-06-16 |
JPH09500104A (ja) | 1997-01-07 |
EP1300156A3 (de) | 2003-05-07 |
EP0699076A4 (de) | 1999-09-08 |
DK0699076T3 (da) | 2003-03-03 |
US6562349B1 (en) | 2003-05-13 |
JP3429313B2 (ja) | 2003-07-22 |
EP0699076A1 (de) | 1996-03-06 |
ES2185658T3 (es) | 2003-05-01 |
DE69431624D1 (de) | 2002-12-05 |
EP0699076B1 (de) | 2002-10-30 |
US6030626A (en) | 2000-02-29 |
PT699076E (pt) | 2003-03-31 |
EP1300156A2 (de) | 2003-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69431624T2 (de) | Impfstoff gegen mittelohrentzündung | |
IL114809A0 (en) | Mutant br96 antibodies | |
NO953033L (no) | Stabile baktericid/permeabilitetsökende proteinprodukter og farmasöytiske preparater inneholdende disse | |
DE3770915D1 (de) | Menschliches apolipoprotein a1 sowie dessen variante, exprimiert in escherichia coli. | |
EP0804609A4 (de) | NEUARTIGE AUF p53 ANSPRECHENDE GENE | |
HUP9801638A2 (hu) | Kevésbé adszorbeálódó és jobban hidrolizáló proteáz K variánsok | |
DE69217144D1 (de) | Regulator-DNA zur Gen-Expression | |
DE69129604D1 (de) | Mutierte beta-Lactamacylasegene | |
ATE255165T1 (de) | Rekombinantes mersacidin und verfahren zu seiner herstellung | |
AU8258591A (en) | Human mk gene and protein sequence | |
AUPP627498A0 (en) | Novel peptides - i | |
EP1251176A3 (de) | Expressionssysteme, die selbstspaltende Fusionsproteine verwenden sowie ein reduzierendes Polypeptid | |
WO2001044289A3 (en) | Modified leukotoxin gene and protein | |
AU4568496A (en) | Acarbose biosynthesis genes from Actinoplanes sp., process for the isolation thereof and the use thereof | |
WO2001066759A3 (en) | 26886, a novel carnitine acyltransferase family member and uses therefor | |
MXPA01011563A (es) | Una novedosa proteina 5 relacionada al factro-h y anticuerpos relacionados. | |
ATE107694T1 (de) | Für a.nidulans-isopenicillin-n-synthetase codierende dns, deren verwendung und dafür codierende vektoren. | |
WO2002026817A3 (en) | 33521, a human guanine nucleotide exchange family member and uses thereof | |
EP1158052A4 (de) | Beta-primeverosidase gen | |
TH10372EX (th) | จีนเซฟาโลสปอรินแอเซทิลไฮโดรเลสและโปรตีนที่ประมวลรหัสไว้ในจีนดังกล่าว | |
WO2001096545A3 (en) | 50090, a human hydratase and uses thereof | |
WO2002062962A3 (en) | 60491, a novel human acyltransferase family member and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |