AU8258591A - Human mk gene and protein sequence - Google Patents

Human mk gene and protein sequence

Info

Publication number
AU8258591A
AU8258591A AU82585/91A AU8258591A AU8258591A AU 8258591 A AU8258591 A AU 8258591A AU 82585/91 A AU82585/91 A AU 82585/91A AU 8258591 A AU8258591 A AU 8258591A AU 8258591 A AU8258591 A AU 8258591A
Authority
AU
Australia
Prior art keywords
human
gene
protein sequence
protein
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU82585/91A
Other versions
AU636789B2 (en
Inventor
Peter Bohlen
Imre Kovesdi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of AU8258591A publication Critical patent/AU8258591A/en
Application granted granted Critical
Publication of AU636789B2 publication Critical patent/AU636789B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to novel DNA and amino sequences for a human MK protein. Also described are expression vectors and host cells useful in a method for production of the MK protein.
AU82585/91A 1990-08-20 1991-08-19 Human mk gene and protein sequence Ceased AU636789B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56857390A 1990-08-20 1990-08-20
US650795 1991-02-05
US568573 1991-02-05
US07/650,795 US5210026A (en) 1990-08-20 1991-02-05 Human mk gene and method of expression

Publications (2)

Publication Number Publication Date
AU8258591A true AU8258591A (en) 1992-02-27
AU636789B2 AU636789B2 (en) 1993-05-06

Family

ID=27074824

Family Applications (1)

Application Number Title Priority Date Filing Date
AU82585/91A Ceased AU636789B2 (en) 1990-08-20 1991-08-19 Human mk gene and protein sequence

Country Status (13)

Country Link
US (1) US5210026A (en)
EP (1) EP0476233B1 (en)
JP (1) JPH06217778A (en)
KR (1) KR920004570A (en)
AT (1) ATE134219T1 (en)
AU (1) AU636789B2 (en)
CA (1) CA2049370A1 (en)
DE (1) DE69117123T2 (en)
DK (1) DK0476233T3 (en)
ES (1) ES2085928T3 (en)
GR (1) GR3019059T3 (en)
NZ (1) NZ239357A (en)
PT (1) PT98694A (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5461029A (en) * 1992-04-24 1995-10-24 American Cyanamid Company Method of treating herpes viral infections using HBNF and MK proteins
GB9225928D0 (en) * 1992-12-11 1993-02-03 Cancer Res Campaign Tech Growth factor
US5534615A (en) * 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
US6472585B1 (en) 1994-04-25 2002-10-29 Genentech, Inc. Cardiotrophin-1 defective mouse
US7258983B2 (en) * 1994-04-25 2007-08-21 Genentech, Inc. Cardiotrophin-1 compositions and methods for the treatment of tumor
DK0755446T3 (en) * 1994-04-25 2007-01-29 Genentech Inc Cardiotrophin and its uses
JPH0995454A (en) * 1995-10-02 1997-04-08 Meiji Milk Prod Co Ltd Antiulcerative composition
US5859311A (en) * 1995-11-27 1999-01-12 University Of Kentucky Research Foundation Transgenic mice which overexpress neurotrophin-3 (NT-3) and methods of use
EP0937461B1 (en) * 1996-07-10 2005-07-06 Meiji Dairies Corporation Use of proteins from the mk family as hematopoietic factor
CA2283954A1 (en) 1997-03-12 1998-09-17 Meiji Milk Products Co., Ltd. Preventive and therapeutic compositions for drug induced nephropathy and hepatitis
EP0998941B9 (en) * 1997-07-14 2007-03-14 Takashi Muramatsu Use of midkine or of anti-midkine antibodies
US8106009B2 (en) * 1997-09-26 2012-01-31 Medical Therapies Limited Pharmaceutical composition for preventing or treating ischemic diseases
AU1486801A (en) * 1999-11-15 2001-05-30 Curagen Corporation Novel growth factor polypeptides and nucleic acids encoding same
EP1545608A4 (en) 2002-06-28 2006-09-13 Centocor Inc Mammalian ch1 deleted mimetibodies, compositions, methods and uses
GB0228776D0 (en) * 2002-12-10 2003-01-15 Ares Trading Sa Splice variant
ES2376332T3 (en) * 2004-06-23 2012-03-13 Tissuegene, Inc. REGENERATION OF NERVES.
EP1904113B1 (en) * 2005-06-23 2016-01-06 TissueGene, Inc. Neuroprotective effective compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI890342A (en) * 1988-01-25 1989-07-26 American Cyanamid Co HJAERNMITOGENER, SOM BINDS TILL HEPARIN.

Also Published As

Publication number Publication date
CA2049370A1 (en) 1992-02-21
NZ239357A (en) 1993-07-27
DK0476233T3 (en) 1996-03-11
GR3019059T3 (en) 1996-05-31
DE69117123T2 (en) 1996-10-02
AU636789B2 (en) 1993-05-06
DE69117123D1 (en) 1996-03-28
ATE134219T1 (en) 1996-02-15
KR920004570A (en) 1992-03-27
EP0476233A1 (en) 1992-03-25
EP0476233B1 (en) 1996-02-14
PT98694A (en) 1992-07-31
JPH06217778A (en) 1994-08-09
US5210026A (en) 1993-05-11
ES2085928T3 (en) 1996-06-16

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