WO2002062962A3 - 60491, a novel human acyltransferase family member and uses thereof - Google Patents

60491, a novel human acyltransferase family member and uses thereof Download PDF

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Publication number
WO2002062962A3
WO2002062962A3 PCT/US2002/003736 US0203736W WO02062962A3 WO 2002062962 A3 WO2002062962 A3 WO 2002062962A3 US 0203736 W US0203736 W US 0203736W WO 02062962 A3 WO02062962 A3 WO 02062962A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
family member
novel human
expression vectors
Prior art date
Application number
PCT/US2002/003736
Other languages
French (fr)
Other versions
WO2002062962A2 (en
Inventor
Rachel E Meyers
Peter J Olandt
Original Assignee
Millennium Pharm Inc
Rachel E Meyers
Peter J Olandt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Rachel E Meyers, Peter J Olandt filed Critical Millennium Pharm Inc
Priority to AU2002243902A priority Critical patent/AU2002243902A1/en
Priority to US10/184,648 priority patent/US7301016B2/en
Publication of WO2002062962A2 publication Critical patent/WO2002062962A2/en
Publication of WO2002062962A3 publication Critical patent/WO2002062962A3/en
Priority to US11/786,411 priority patent/US7799898B2/en
Priority to US12/828,319 priority patent/US8252915B2/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated 60491 nucleic acid molecules, which encode novel acyltransferase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 60491 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 60491 gene has been introduced or disrupted. The invention still further provides isolated 60491 proteins, fusion proteins, antigenic peptides and anti-60491 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2002/003736 2000-03-07 2002-02-08 60491, a novel human acyltransferase family member and uses thereof WO2002062962A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2002243902A AU2002243902A1 (en) 2001-02-08 2002-02-08 60491, a novel human acyltransferase family member and uses thereof
US10/184,648 US7301016B2 (en) 2000-03-07 2002-06-27 Human transferase family members and uses thereof
US11/786,411 US7799898B2 (en) 2000-03-07 2007-04-11 Human transferase family members and uses thereof
US12/828,319 US8252915B2 (en) 2000-03-07 2010-07-01 Human transferase family members and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26749401P 2001-02-08 2001-02-08
US60/267,494 2001-02-08

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US7228502A Continuation-In-Part 2000-03-07 2002-02-08
US10/184,648 Continuation-In-Part US7301016B2 (en) 2000-03-07 2002-06-27 Human transferase family members and uses thereof

Publications (2)

Publication Number Publication Date
WO2002062962A2 WO2002062962A2 (en) 2002-08-15
WO2002062962A3 true WO2002062962A3 (en) 2003-12-18

Family

ID=23019023

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/003736 WO2002062962A2 (en) 2000-03-07 2002-02-08 60491, a novel human acyltransferase family member and uses thereof

Country Status (2)

Country Link
AU (1) AU2002243902A1 (en)
WO (1) WO2002062962A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049488A (en) * 1985-11-08 1991-09-17 Genentech, Inc. Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049488A (en) * 1985-11-08 1991-09-17 Genentech, Inc. Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase

Also Published As

Publication number Publication date
AU2002243902A1 (en) 2002-08-19
WO2002062962A2 (en) 2002-08-15

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