HRP20100538T1 - 5,6-dialkil-7-aminotriazolopirimidini, postupci za njihovo dobijanje, njihova primjena za kontrolu patogenih gljiva, kao i sredstva koja sadrže spomenute spojeve - Google Patents

5,6-dialkil-7-aminotriazolopirimidini, postupci za njihovo dobijanje, njihova primjena za kontrolu patogenih gljiva, kao i sredstva koja sadrže spomenute spojeve Download PDF

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Publication number
HRP20100538T1
HRP20100538T1 HR20100538T HRP20100538T HRP20100538T1 HR P20100538 T1 HRP20100538 T1 HR P20100538T1 HR 20100538 T HR20100538 T HR 20100538T HR P20100538 T HRP20100538 T HR P20100538T HR P20100538 T1 HRP20100538 T1 HR P20100538T1
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Croatia
Prior art keywords
formula
ethyl
ylamine
triazolo
pyrimidin
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HR20100538T
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English (en)
Inventor
Tormo I Blasco Jordi
Blettner Carsten
Mller Bernd
Gewehr Markus
Grammenos Wassilios
Grote Thomas
Rheinheimer Joachim
Sch�fer Peter
Schieweck Frank
Schw�gler Anja
Wagner Oliver
Niedenbr�ck Matthias
Scherer Maria
Strathmann Siegfried
Sch�fl Ulrich
Stierl Reinhard
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Basf Se
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Publication of HRP20100538T1 publication Critical patent/HRP20100538T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catching Or Destruction (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Triazolopirimidini formule Inaznačeni time, što supstituenti imaju slijedeće značenje: R1 je C5-C12-alkil ili C5-C14-alkoksialkil, pri čemu alifatične grupe mogu biti supstituirane sa jednom do tri slijedeće grupe: cijano, nitro, hidroksi, C3-C6-cikloalkil, C1-C6-alkiltio i NRaRb;Ra, Rb su vodik ili C1-C6-alkil; R2 je etil, CH=CH2 ili CH2CH=CH2.Patent sadrži još 9 patentnih zahtjeva.

Claims (10)

1. Triazolopirimidini formule I [image] naznačeni time, što supstituenti imaju slijedeće značenje: R1 je C5-C12-alkil ili C5-C14-alkoksialkil, pri čemu alifatične grupe mogu biti supstituirane sa jednom do tri slijedeće grupe: cijano, nitro, hidroksi, C3-C6-cikloalkil, C1-C6-alkiltio i NRaRb; Ra, Rb su vodik ili C1-C6-alkil; R2 je etil, CH=CH2 ili CH2CH=CH2.
2. Spojevi formule I prema zahtjevu 1, naznačeni time, što R2 označava etil.
3. Spojevi formule I prema zahtjevu 1, naznačeni time, što R1 označava nesupstituirani, nerazgranati ili jednostruko, dvostruko ili trostruko razgranati alkilni lanac sa do 12 atoma ugljika.
4. Triazolopirimidini formule I prema zahtjevu 1 naznačeni time, što su izabrani iz grupe koja sadrži: 5-etil-6-(1-metil-heptil)-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-oktil-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-(3,5,5-trimetil-heksil)-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-pentil-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-heksil-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-heptil-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-nonil-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-undecil-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin; 5-etil-6-(3-pentiloksi-propil)-[1,2,4]triazolo[1,5-a]pirimidin-7-ilamin.
5. Postupak za dobijanje spojeva formule I prema jednom od zahtjeva 1 do 4, naznačen time, što β-keto ester formule II, [image] u kojoj R označava C1-C4-alkil, reagira sa 3-amino-1,2,4-triazolom formule III [image] u 7-hidroksitriazolopirimidine formule IV [image] koji se halogenira u spojeve formule V, [image] u kojoj Hal označava klor ili brom, a zatim V reagira sa amonijakom.
6. Spojevi formula IV i V, naznačeni time, što su u skladu sa zahtjevom 5.
7. Postupak za dobijanje spojeva formule I prema jednom od zahtjeva 1 do 4, naznačen time, što acilcijanidi formule VI [image] reagiraju sa 3-amino-1,2,4-triazolom formule III prema zahtjevu 5.
8. Fungicidno sredstvo, naznačeno time, što sadrži čvrsti ili tekući nosač i spoj formule I prema jednom od zahtjeva 1 do 4.
9. Sjeme naznačeno time, što sadrži spoj formule I prema jednom od zahtjeva 1 do 4 u količini od 1 do na .
10. Postupak za kontrolu fitopatogenih štetnih gljiva, naznačen time, što se gljive ili materijali, biljke, tlo ili sjeme koje treba zaštititi od gljivične zaraze, tretiraju sa djelotvornom količinom spojeva formule I prema jednom od zahtjeva 1 do 4.
HR20100538T 2004-03-10 2010-10-04 5,6-dialkil-7-aminotriazolopirimidini, postupci za njihovo dobijanje, njihova primjena za kontrolu patogenih gljiva, kao i sredstva koja sadrže spomenute spojeve HRP20100538T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004012011 2004-03-10
PCT/EP2005/002427 WO2005087773A1 (de) 2004-03-10 2005-03-08 5,6-dialkyl-7-amino-triazolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel

Publications (1)

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HRP20100538T1 true HRP20100538T1 (hr) 2010-12-31

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HR20100538T HRP20100538T1 (hr) 2004-03-10 2010-10-04 5,6-dialkil-7-aminotriazolopirimidini, postupci za njihovo dobijanje, njihova primjena za kontrolu patogenih gljiva, kao i sredstva koja sadrže spomenute spojeve

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US (1) US9487519B2 (hr)
EP (1) EP1725561B1 (hr)
JP (2) JP5005528B2 (hr)
KR (1) KR101306446B1 (hr)
CN (1) CN1930166B (hr)
AP (1) AP2264A (hr)
AR (1) AR048813A1 (hr)
AT (1) ATE473228T1 (hr)
AU (1) AU2005221808B8 (hr)
BR (1) BRPI0508281B1 (hr)
CA (1) CA2557781C (hr)
CR (1) CR8551A (hr)
DE (1) DE502005009862D1 (hr)
DK (1) DK1725561T3 (hr)
EA (1) EA010411B1 (hr)
EC (1) ECSP066829A (hr)
EG (1) EG24617A (hr)
ES (1) ES2347664T3 (hr)
HR (1) HRP20100538T1 (hr)
IL (1) IL177361A (hr)
MA (1) MA28523B1 (hr)
NO (1) NO20064133L (hr)
NZ (1) NZ549218A (hr)
PE (1) PE20051137A1 (hr)
PL (1) PL1725561T3 (hr)
PT (1) PT1725561E (hr)
RS (1) RS51454B (hr)
SI (1) SI1725561T1 (hr)
TW (1) TWI348354B (hr)
UA (1) UA81873C2 (hr)
UY (1) UY28800A1 (hr)
WO (1) WO2005087773A1 (hr)
ZA (1) ZA200608384B (hr)

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