HK1143738A1 - Ido inhibitors ido - Google Patents

Ido inhibitors ido

Info

Publication number
HK1143738A1
HK1143738A1 HK10110228.1A HK10110228A HK1143738A1 HK 1143738 A1 HK1143738 A1 HK 1143738A1 HK 10110228 A HK10110228 A HK 10110228A HK 1143738 A1 HK1143738 A1 HK 1143738A1
Authority
HK
Hong Kong
Prior art keywords
indoleamine
dioxygenase
compound
administering
aspects described
Prior art date
Application number
HK10110228.1A
Other languages
English (en)
Inventor
Mario Mautino
Firoz Jaipuri
Agnieszka Marcinowicz-Flick
Tanay Kesharwani
Jesse Waldo
Steven James Collier
Original Assignee
Newlink Genetics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newlink Genetics filed Critical Newlink Genetics
Publication of HK1143738A1 publication Critical patent/HK1143738A1/xx

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    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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CN101932325A (zh) 2010-12-29
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JP5583592B2 (ja) 2014-09-03
EP2227233B1 (en) 2013-02-13
WO2009073620A2 (en) 2009-06-11
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JP2011505379A (ja) 2011-02-24
CA2932121A1 (en) 2009-06-11
US20130289083A1 (en) 2013-10-31
CN101932325B (zh) 2014-05-28
CA2707308A1 (en) 2009-06-11
US20110053941A1 (en) 2011-03-03
CA2707308C (en) 2016-08-02
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