FR14C0034I1 - - Google Patents

Info

Publication number
FR14C0034I1
FR14C0034I1 FR14C0034C FR14C0034I1 FR 14C0034 I1 FR14C0034 I1 FR 14C0034I1 FR 14C0034 C FR14C0034 C FR 14C0034C FR 14C0034 I1 FR14C0034 I1 FR 14C0034I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34115515&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR14C0034(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of FR14C0034I1 publication Critical patent/FR14C0034I1/fr
Application granted granted Critical
Publication of FR14C0034I2 publication Critical patent/FR14C0034I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
FR14C0034C 2003-08-01 2014-04-18 Nouveaux composes possedant une activite inhibitrice dirigee contre le transporteur dependant du sodium Active FR14C0034I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49153403P 2003-08-01 2003-08-01
PCT/JP2004/011312 WO2005012326A1 (fr) 2003-08-01 2004-07-30 Nouveaux composes possedant une activite inhibitrice dirigee contre le transporteur dependant du sodium

Publications (2)

Publication Number Publication Date
FR14C0034I1 true FR14C0034I1 (fr) 2014-06-13
FR14C0034I2 FR14C0034I2 (fr) 2014-11-14

Family

ID=34115515

Family Applications (1)

Application Number Title Priority Date Filing Date
FR14C0034C Active FR14C0034I2 (fr) 2003-08-01 2014-04-18 Nouveaux composes possedant une activite inhibitrice dirigee contre le transporteur dependant du sodium

Country Status (37)

Country Link
US (3) US7943788B2 (fr)
EP (4) EP2514756B1 (fr)
JP (2) JP4130466B2 (fr)
KR (2) KR100778988B1 (fr)
CN (4) CN103214471B (fr)
AR (1) AR045173A1 (fr)
AU (1) AU2004260761B2 (fr)
BE (1) BE2014C027I2 (fr)
BR (1) BRPI0413232B8 (fr)
CA (1) CA2534024C (fr)
CR (2) CR8188A (fr)
CY (3) CY1113813T1 (fr)
DK (2) DK1651658T4 (fr)
EA (2) EA015104B1 (fr)
ES (4) ES2844401T3 (fr)
FR (1) FR14C0034I2 (fr)
HK (1) HK1086277A1 (fr)
HR (2) HRP20130124T4 (fr)
HU (2) HUE037320T2 (fr)
IL (2) IL173050A (fr)
LT (1) LT2896397T (fr)
LU (1) LU92426I2 (fr)
ME (1) ME00411B (fr)
MX (1) MXPA06001274A (fr)
MY (1) MY143203A (fr)
NL (1) NL300670I2 (fr)
NO (3) NO333933B1 (fr)
NZ (2) NZ575711A (fr)
PL (2) PL1651658T5 (fr)
PT (2) PT2896397T (fr)
RS (1) RS53365B (fr)
SG (1) SG145694A1 (fr)
SI (2) SI2896397T2 (fr)
TW (2) TWI385177B (fr)
UA (1) UA83243C2 (fr)
WO (1) WO2005012326A1 (fr)
ZA (5) ZA200601685B (fr)

Families Citing this family (199)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1020944C (zh) * 1990-01-30 1993-05-26 阿图尔-费希尔股份公司费希尔厂 紧固件
PT1980560E (pt) 2003-03-14 2011-06-29 Astellas Pharma Inc Derivados de c-glicósido para o tratamento da diabetes
EP2514756B1 (fr) † 2003-08-01 2014-12-17 Mitsubishi Tanabe Pharma Corporation Nouveaux composés présentant une activité inhibitrice contre le transporteur dépendant du sodium
ZA200608028B (en) * 2004-03-04 2009-03-25 Kissei Pharmaceutical Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
WO2005092877A1 (fr) 2004-03-16 2005-10-06 Boehringer Ingelheim International Gmbh Derives du benzol substitues par un glucopyranosyle,, medicaments renfermant ces composes, leur utilisation et leur procede de production
US7393836B2 (en) 2004-07-06 2008-07-01 Boehringer Ingelheim International Gmbh D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
CA2574451A1 (fr) * 2004-07-27 2006-02-02 Boehringer Ingelheim International Gmbh Cyclenes substitues par d-glucopyranosyle-phenyle, medicaments contenant lesdits composes, leur utilisation et procede de production correspondant
WO2006035796A1 (fr) * 2004-09-29 2006-04-06 Kissei Pharmaceutical Co., Ltd. COMPOSÉ HÉTÉROCYCLIQUE AZOTÉ 1-(β-D-GLYCOPYRANOSYL)-3-SUBSTITUÉ, PRÉPARATION THÉRAPEUTIQUE CONTENANT LEDIT COMPOSÉ, ET EMPLOI MÉDICAL DUDIT COMPOSÉ
CA2587639A1 (fr) 2004-12-16 2006-06-22 Boehringer Ingelheim International Gmbh Derives de benzene substitues par glucopyranosyle, medicaments contenant ces composes, leur utilisation et leur procede de fabrication
TW200637869A (en) 2005-01-28 2006-11-01 Chugai Pharmaceutical Co Ltd The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
JP4496174B2 (ja) * 2005-01-31 2010-07-07 田辺三菱製薬株式会社 医薬組成物
MY147375A (en) * 2005-01-31 2012-11-30 Mitsubishi Tanabe Pharma Corp Indole derivatives
AR053329A1 (es) * 2005-01-31 2007-05-02 Tanabe Seiyaku Co Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
EP1856082B1 (fr) 2005-02-23 2009-10-14 Boehringer Ingelheim International GmbH Derives d'(hetero)arylethynyl-benzyl-benzene a substitution glucopyranosyle et leur utilisation en tant qu'inhibiteurs du cotransporteur 2 de glucose dependant de sodium (sglt2)
WO2006108842A1 (fr) 2005-04-15 2006-10-19 Boehringer Ingelheim International Gmbh Derives de glucopyranosyl-substitue (heteroaryloxy-benzyl)-benzene utilises comme inhibiteurs de sglt
UA91546C2 (uk) 2005-05-03 2010-08-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
US7723309B2 (en) 2005-05-03 2010-05-25 Boehringer Ingelheim International Gmbh Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
US7772191B2 (en) 2005-05-10 2010-08-10 Boehringer Ingelheim International Gmbh Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
TW200726755A (en) * 2005-07-07 2007-07-16 Astellas Pharma Inc A crystalline choline salt of an azulene derivative
JP5128474B2 (ja) 2005-07-27 2013-01-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルコピラノシル−置換（（ヘテロ）シクロアルキルエチニル−ベンジル）−ベンゼン誘導体、該化合物を含有する薬剤、それらの使用及びそれらの製造方法
ATE484499T1 (de) 2005-08-30 2010-10-15 Boehringer Ingelheim Int Glucopyranosyl-substituierte benzyl-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür
TW200745075A (en) 2005-09-08 2007-12-16 Boehringer Ingelheim Int Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-(4-ethynyl-benzyl)-benzene, methods for its preparation and the use thereof for preparing medicaments
AR056195A1 (es) * 2005-09-15 2007-09-26 Boehringer Ingelheim Int Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos
EA200801773A1 (ru) 2006-02-15 2009-02-27 Бёрингер Ингельхайм Интернациональ Гмбх Глюкопиранозилзамещенные производные бензонитрила, фармацевтические композиции, содержащие такие соединения, их применение и способ их получения
TWI370818B (en) 2006-04-05 2012-08-21 Astellas Pharma Inc Cocrystal of c-glycoside derivative and l-proline
PE20080697A1 (es) 2006-05-03 2008-08-05 Boehringer Ingelheim Int Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
WO2007140191A2 (fr) 2006-05-23 2007-12-06 Theracos, Inc. Inhibiteurs de transport de glucose et procédés d'utilisation
TWI418556B (zh) * 2006-07-27 2013-12-11 Mitsubishi Tanabe Pharma Corp 吲哚衍生物
TWI432446B (zh) 2006-07-27 2014-04-01 Chugai Pharmaceutical Co Ltd 稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
TWI403516B (zh) 2006-07-27 2013-08-01 Chugai Pharmaceutical Co Ltd To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
US20080027014A1 (en) * 2006-07-28 2008-01-31 Tanabe Seiyaku Co., Ltd. Novel SGLT inhibitors
JP5384343B2 (ja) 2006-08-15 2014-01-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルコピラノシル−置換シクロプロピルベンゼン誘導体、そのような化合物を含む医薬組成物、ｓｇｌｔ阻害剤としてのそれらの使用及びそれらの製造方法
JP5372759B2 (ja) * 2006-09-21 2013-12-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルコピラノシル−置換ジフルオロベンジル−ベンゼン誘導体、該化合物を含有する医薬品及びその使用と調製方法
US20100093744A1 (en) 2006-10-13 2010-04-15 Chugai Seiyaku Kabushiki Kaisha Thioglucose spiroketal derivative and use thereof as therapeutic agent for diabetes
EP2086991A1 (fr) 2006-10-27 2009-08-12 Boehringer Ingelheim International GmbH FORME CRISTALLINE DU 4-(ß-D-GLUCOPYRANOS-1-YL)-1-MÉTHYL-2-[4-((S)-TÉTRAHYDROFURAN-3-YLOXY)BENZYL]-BENZÈNE, PROCÉDÉ POUR LA PRÉPARATION DE CELLE-CI ET UTILISATION DE CELLE-CI POUR PRÉPARER DES MÉDICAMENTS
JP5298025B2 (ja) * 2006-12-04 2013-09-25 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗糖尿病薬としてのチエニル含有グリコピラノシル誘導体
UY30730A1 (es) 2006-12-04 2008-07-03 Mitsubishi Tanabe Pharma Corp Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
CA2673498C (fr) * 2006-12-21 2012-04-24 Astellas Pharma Inc. Procede de fabrication d'un derive de c-glycoside et intermediaire de synthese de celui-ci
US7795228B2 (en) * 2006-12-28 2010-09-14 Theracos, Inc. Spiroheterocyclic glycosides and methods of use
WO2008103618A1 (fr) * 2007-02-22 2008-08-28 University Of Utah Research Foundation Synthèse de nouveaux xylosides et leurs utilisations potentielles
CA2682202C (fr) 2007-04-02 2016-01-12 Theracos, Inc. Derives de glycoside benzylique et procedes d'utilisation
CA2684021A1 (fr) * 2007-04-11 2008-10-23 N.V. Organon Procedes de preparation d'un enantiomere d'une benzazepine tetracyclique
CL2008002427A1 (es) 2007-08-16 2009-09-11 Boehringer Ingelheim Int Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
KR101107425B1 (ko) 2007-08-23 2012-01-19 테라코스, 인코포레이티드 벤질벤젠 유도체 및 사용 방법
US9024009B2 (en) * 2007-09-10 2015-05-05 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
UA101004C2 (en) 2007-12-13 2013-02-25 Теракос, Инк. Derivatives of benzylphenylcyclohexane and use thereof
CL2008003653A1 (es) * 2008-01-17 2010-03-05 Mitsubishi Tanabe Pharma Corp Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
WO2009096455A1 (fr) 2008-01-31 2009-08-06 Astellas Pharma Inc. Composition pharmaceutique pour le traitement de stéatoses hépatiques
UY31651A1 (es) * 2008-02-13 2009-09-30 Nuevos derivados de fluoroglicósidos aromáticos, medicamentos que comprenden estos compuestos y uso de los mismos.
MX2010012656A (es) 2008-05-22 2010-12-20 Squibb Bristol Myers Co Metodo para tratar la hiperuricemia empleando un inhibidor de sglt2 y composicion que contiene el mismo.
EP2324002B1 (fr) 2008-08-22 2016-10-05 Theracos Sub, LLC Procédés de préparation d'inhibiteurs de sglt2
DK2334687T5 (da) 2008-08-28 2012-09-10 Pfizer Dioxa-bicyclo[3.2.1.]octan-2,3,4-triol-derivater
US20110269700A1 (en) * 2008-09-19 2011-11-03 Novartis Ag Glucoside derivatives and uses thereof
US9056850B2 (en) * 2008-10-17 2015-06-16 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
UY32441A (es) 2009-02-13 2010-09-30 Boehringer Ingelheim Int Composicion farmaceutica, metodos de tratamiento y sus usos
CN101830876A (zh) * 2009-03-12 2010-09-15 上海恒瑞医药有限公司 C-芳基葡萄糖苷衍生物、其制备方法及其在医药上的应用
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
EA022186B1 (ru) 2009-07-10 2015-11-30 Янссен Фармацевтика Нв СПОСОБ КРИСТАЛЛИЗАЦИИ 1-(β-D-ГЛЮКОПИРАНОЗИЛ)-4-МЕТИЛ-3-[5-(4-ФТОРФЕНИЛ)-2-ТИЕНИЛМЕТИЛ]БЕНЗОЛА
WO2011034846A1 (fr) 2009-09-15 2011-03-24 Janssen Pharmaceutica, N.V. Utilisation d'alpha-méthylglucoside (amg) en tant qu'indicateur de l'absorption et de l'excrétion du glucose
EP2483286B1 (fr) 2009-09-30 2016-07-13 Boehringer Ingelheim International GmbH Procédé de préparation d'une forme cristalline de 1-chloro-4-( -d-glucopyranos-1-yl)-2-[4-((s)-tétrahydrofuran-3-yloxy)-benzyl]-benzène
DK2486029T3 (en) 2009-09-30 2015-08-24 Boehringer Ingelheim Int Methods of making of glucopyranosyl-substituted benzyl-benzene derivatives.
US10610489B2 (en) 2009-10-02 2020-04-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
HUE031375T2 (en) * 2009-10-14 2017-07-28 Janssen Pharmaceutica Nv A method for preparing compounds useful as SGLT2 inhibitors
US8163704B2 (en) 2009-10-20 2012-04-24 Novartis Ag Glycoside derivatives and uses thereof
ES2527179T3 (es) 2009-11-02 2015-01-21 Pfizer Inc. Derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol
CN102115468B (zh) * 2009-12-31 2014-06-11 上海特化医药科技有限公司 一种2,5-二取代噻吩化合物的合成方法
CN102134226B (zh) * 2010-01-26 2013-06-12 天津药物研究院 一类苯基c-葡萄糖苷衍生物、其制备方法和用途
WO2011120923A1 (fr) 2010-03-30 2011-10-06 Boehringer Ingelheim International Gmbh Composition pharmaceutique comprenant un inhibiteur sglt2 et un agoniste ppar-gamma, utilisations correspondantes
JP2013523819A (ja) 2010-04-06 2013-06-17 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置
JP5596799B2 (ja) * 2010-05-11 2014-09-24 田辺三菱製薬株式会社 カナグリフロジン含有錠剤
JO3577B1 (ar) 2010-05-11 2020-07-05 Janssen Pharmaceutica Nv صيغ صيدلانية تشمل مشتقات 1-(بيتا-d- غلوكوبيرانوسيل) -2-ثينيل ميثيل بنزين كمثبطات sglt
US8217183B2 (en) 2010-05-18 2012-07-10 Corning Incorporated Methods of making fused thiophenes
WO2011153712A1 (fr) 2010-06-12 2011-12-15 Theracos, Inc. Forme cristalline d'inhibiteur de sglt2 de type benzyl-benzène
CA2804506C (fr) 2010-07-06 2018-08-21 Janssen Pharmaceutica Nv Formulation pour le traitement par co-therapie du diabete
CN102372722A (zh) 2010-08-10 2012-03-14 江苏恒瑞医药股份有限公司 C-芳基葡萄糖苷衍生物、其制备方法及其在医药上的应用
WO2012033390A2 (fr) * 2010-09-10 2012-03-15 Green Cross Corporation Nouveau dérivé du thiophène utilisé comme inhibiteur du sglt2 et composition pharmaceutique comprenant ce dérivé
CA2812061A1 (fr) 2010-09-22 2012-03-29 Arena Pharmaceuticals, Inc. Modulateurs du recepteur gpr119 et traitement des troubles qui lui sont lies
WO2012041898A1 (fr) 2010-09-29 2012-04-05 Celon Pharma Sp. Z O.O. Combinaison de l'inhibiteur de sglt2 et d'un composé de sucre pour le traitement du diabète
CN102453026A (zh) 2010-10-27 2012-05-16 上海艾力斯医药科技有限公司 C-芳基葡糖苷衍生物、制备方法及其应用
US20120283169A1 (en) 2010-11-08 2012-11-08 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US20130035281A1 (en) 2011-02-09 2013-02-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
EP2676965B1 (fr) 2011-02-18 2017-10-04 Shanghai Yingli Pharmaceutical Co., Ltd Composé aryl glycoside, son procédé de préparation et d'utilisation
AR085689A1 (es) 2011-03-07 2013-10-23 Boehringer Ingelheim Int Composiciones farmaceuticas de metformina, linagliptina y un inhibidor de sglt-2
WO2012135570A1 (fr) 2011-04-01 2012-10-04 Arena Pharmaceuticals, Inc. Modulateurs du récepteur gpr119 et traitement de troubles qui lui sont associés
WO2012140120A1 (fr) * 2011-04-13 2012-10-18 Janssen Pharmaceutica Nv Procédé de préparation de composés utiles en tant qu'inhibiteurs de sglt2
WO2012139495A1 (fr) 2011-04-13 2012-10-18 Merck Sharp & Dohme Corp. Antagonistes des récepteurs de minéralocorticoïdes
MX2013011926A (es) * 2011-04-14 2013-11-01 Novartis Ag Derivados de glicosido y usos de los mismos.
WO2012145361A1 (fr) 2011-04-19 2012-10-26 Arena Pharmaceuticals, Inc. Modulateurs du récepteur gpr119 et traitement de troubles liés à celui-ci
WO2012145603A1 (fr) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulateurs du récepteur gpr119 et traitement de troubles liés à celui-ci
WO2012145604A1 (fr) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulateurs du récepteur gpr119 et traitement de troubles liés à celui-ci
TWI542596B (zh) * 2011-05-09 2016-07-21 健生藥品公司 （２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體
WO2012162113A1 (fr) * 2011-05-20 2012-11-29 Janssen Pharmaceutica Nv Procédé de synthèse de composés pouvant être employés comme inhibiteurs de sglt-2
EP2712359B1 (fr) 2011-05-20 2017-06-21 Janssen Pharmaceutica NV Procédé de préparation de composés utiles à titre d'inhibiteurs de sglt-2
US9034921B2 (en) * 2011-06-01 2015-05-19 Green Cross Corporation Diphenylmethane derivatives as SGLT2 inhibitors
JP5835598B2 (ja) 2011-06-03 2015-12-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 神経弛緩剤で治療されている患者において代謝性障害を治療するためのｓｇｌｔ−２阻害剤
WO2012170702A1 (fr) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulateurs du récepteur gpr119 et traitement de troubles associés à celui-ci
CN102827122B (zh) * 2011-06-17 2015-01-14 山东轩竹医药科技有限公司 糖苷衍生物
WO2013055910A1 (fr) 2011-10-12 2013-04-18 Arena Pharmaceuticals, Inc. Modulateurs du récepteur gpr119 et traitement de troubles associés
WO2013061105A2 (fr) * 2011-10-28 2013-05-02 Debreceni Egyetem Inhibiteurs de phosphorylase de glycogène
WO2013090550A1 (fr) * 2011-12-15 2013-06-20 National Health Research Institutes Nouveaux composés glycosides
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
US9192617B2 (en) 2012-03-20 2015-11-24 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US9193751B2 (en) 2012-04-10 2015-11-24 Theracos, Inc. Process for the preparation of benzylbenzene SGLT2 inhibitors
CN103570671B (zh) * 2012-09-26 2016-03-30 上海天慈生物谷生物工程有限公司 一种降糖化合物及其制法和应用
WO2014074668A1 (fr) 2012-11-08 2014-05-15 Arena Pharmaceuticals, Inc. Modulateurs de gpr119 et traitement de troubles associés à ceux-ci
EP2933250B1 (fr) * 2012-12-17 2017-08-09 Tianjin Institute Of Pharmaceutical Research Dérivé de phényl-c-glucoside contenant une structure de désoxyglucose, procédé de préparation et utilisation de celui-ci
CN103910769B (zh) 2012-12-31 2018-10-02 上海璎黎药业有限公司 葡萄糖衍生物和脯氨酸的复合物、晶体、制备方法及应用
EP2963048B1 (fr) * 2013-02-26 2020-11-18 Mitsubishi Tanabe Pharma Corporation Procédé de production d'un alpha-halo-tétraacyl-glucose
CA2903747C (fr) * 2013-03-11 2021-08-10 Janssen Pharmaceutica Nv Inhibiteurs doubles de sglt1/sglt2
EP3466431B1 (fr) 2013-03-14 2023-11-15 MSD International GmbH Formes crystallins et modes preparatoires pour la manufacture des inhibiteurs de sglt2
ES2647526T3 (es) 2013-03-15 2017-12-22 Janssen Pharmaceutica Nv Combinación de canagliflozina y probenecid para el tratamiento de la hiperuricemia
HUE064190T2 (hu) 2013-04-04 2024-03-28 Boehringer Ingelheim Vetmedica Gmbh Lófélék anyagcserezavarainak kezelése
US20140303097A1 (en) 2013-04-05 2014-10-09 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
HUE041709T2 (hu) 2013-04-05 2019-05-28 Boehringer Ingelheim Int Az empagliflozin terápiás alkalmazásai
US11813275B2 (en) 2013-04-05 2023-11-14 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
MX2015014512A (es) 2013-04-18 2016-02-09 Boehringer Ingelheim Int Composicion farmaceutica, metodos para tratamiento y sus usos.
MX355831B (es) 2013-05-08 2018-05-02 Lek Pharmaceuticals NOVEDOSOS HIDRATOS CRISTALINOS DE 1-(ß-D-GLUCOPIRANOSIL)-4-METIL-3 -[5-(4-FLUORO-FENIL)-2-TIENIL-METIL]-BENCENO.
WO2014195966A2 (fr) 2013-05-30 2014-12-11 Cadila Healthcare Limited Forme amorphe de canagliflozine et son procédé de préparation
CN104418834B (zh) * 2013-08-23 2017-09-15 重庆博腾制药科技股份有限公司 一种抗糖尿病药物中间体的合成方法
WO2015051484A1 (fr) 2013-10-12 2015-04-16 Theracos, Inc. Préparation de dérivés d'hydroxy-benzylbenzène
CN104557894A (zh) * 2013-10-18 2015-04-29 上海信谊药厂有限公司 坎格列汀晶型及其制备方法
HRP20231694T1 (hr) 2013-12-17 2024-03-15 Boehringer Ingelheim Vetmedica Gmbh Sglt-2 inhibitor za uporabu u liječenju metaboličkog poremećaja kod životinja iz porodice mačaka
AU2015208291B2 (en) 2014-01-23 2019-12-05 Boehringer Ingelheim Vetmedica Gmbh Treatment of metabolic disorders in canine animals
EA201691555A1 (ru) 2014-01-31 2017-01-30 Янссен Фармацевтика Нв Способы лечения и предотвращения заболеваний почек и жировых дистрофий печени
EP2918579A1 (fr) 2014-03-14 2015-09-16 LEK Pharmaceuticals d.d. Synthèse de 2-arylméthyl-5-aryl-thiophène
CN105121434B (zh) 2014-03-19 2017-08-29 杭州普晒医药科技有限公司 坎格列净一水合物及其晶型、它们的制备方法和用途
NZ723781A (en) 2014-04-01 2022-09-30 Boehringer Ingelheim Vetmedica Gmbh Treatment of metabolic disorders in equine animals
CN103936725B (zh) * 2014-04-01 2016-07-27 天津大学 卡格列净的c晶型及其结晶制备方法
CN105001213B (zh) 2014-04-14 2020-08-28 上海迪诺医药科技有限公司 C-芳基糖苷衍生物、其药物组合物、制备方法及应用
EP2933255A1 (fr) 2014-04-17 2015-10-21 LEK Pharmaceuticals d.d. Nouvelle forme cristalline de 1-(beta-D-glucopyranosyl)-4- methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene
CN103980263B (zh) * 2014-04-17 2016-08-03 海门瑞一医药科技有限公司 卡格列净的合成工艺
CN103936800A (zh) * 2014-05-08 2014-07-23 安徽联创药物化学有限公司 1-(1-甲氧基吡喃葡糖基)-4-甲基-3-[5-(4-氟苯基)-2-噻吩基甲基]苯的制备方法
TW201623321A (zh) * 2014-05-13 2016-07-01 韓美藥品股份有限公司 雙環衍生物及包含其之藥學組成物
EP2947077A1 (fr) 2014-05-19 2015-11-25 LEK Pharmaceuticals d.d. Synthèse stéréosélective d'intermédiaires dans la préparation de ß-C-arylglucosides
ES2711804T3 (es) * 2014-05-27 2019-05-07 Glenmark Pharmaceuticals Ltd Proceso para preparación de canagliflozina
CN105319294B (zh) * 2014-06-20 2021-03-30 重庆医药工业研究院有限责任公司 一种分离测定卡格列净及其有关物质的方法
US20160002275A1 (en) * 2014-07-03 2016-01-07 Cadila Healthcare Limited Process for preparation and purification of canagliflozin
CN104119324B (zh) * 2014-07-23 2016-03-30 齐鲁天和惠世制药有限公司 一种卡格列净的制备方法
CN104109157B (zh) * 2014-08-04 2016-05-25 山东康美乐医药科技有限公司 卡格列净的制备方法
EP2990029A1 (fr) 2014-08-29 2016-03-02 Sandoz Ag Compositions pharmaceutiques comprenant du canagliflozin
US20170247359A1 (en) 2014-09-05 2017-08-31 Mylan Laboratories Ltd. Process for the preparation of canagliflozin
CN104292209A (zh) * 2014-09-11 2015-01-21 浙江丽晶化学有限公司 一种制备2-(4-氟苯基)噻吩(化合物v)的新方法
CZ2014634A3 (cs) 2014-09-16 2016-03-23 Zentiva, K.S. Komplexy canagliflozinu a cyklodextrinů
CN104817554A (zh) * 2014-11-10 2015-08-05 镇江新元素医药科技有限公司 一类葡萄糖苷衍生物及其药物组合物
CN104478968A (zh) * 2015-01-14 2015-04-01 佛山市赛维斯医药科技有限公司 含噻唑基的o-半乳糖苷衍生物、其制备方法和用途
CN104447906A (zh) * 2015-01-14 2015-03-25 佛山市赛维斯医药科技有限公司 烷氧苯基双葡萄糖苷衍生物、其制备方法和用途
CN104478969A (zh) * 2015-01-14 2015-04-01 佛山市赛维斯医药科技有限公司 含烷氧苯基噻唑基的o-半乳糖苷衍生物、其制备方法和用途
CN104447905A (zh) * 2015-01-14 2015-03-25 佛山市赛维斯医药科技有限公司 一种含硝基苯和双o-葡萄糖苷衍生物、其制备方法和用途
CN104447907A (zh) * 2015-01-14 2015-03-25 佛山市赛维斯医药科技有限公司 含硝基联苯双葡萄糖苷结构化合物、其制备方法和用途
CN104478962A (zh) * 2015-01-15 2015-04-01 佛山市赛维斯医药科技有限公司 一类卤代苯基s-葡萄糖苷衍生物、其制备方法和用途
US10508128B2 (en) 2015-02-09 2019-12-17 Indoco Remedies Limited Process for the preparation of SGLT inhibitor compounds
CN105884755B (zh) * 2015-02-14 2019-05-28 正大天晴药业集团股份有限公司 氘修饰的碳甙衍生物
US10308871B2 (en) 2015-02-19 2019-06-04 Jnc Corporation Liquid crystal compound having benzothiophene, liquid crystal composition and liquid crystal display device
WO2016135747A2 (fr) * 2015-02-27 2016-09-01 Msn Laboratories Private Limited Processus de préparation d'un composé amorphe (1s)-1,5-anhvdro-1-[3- [[5- (4 fluorophényl)-2-thiényl]methvl]-4-méthylphényl]-d-glucitol et de ses formes polymorphes
CN104803977A (zh) * 2015-03-03 2015-07-29 佛山市赛维斯医药科技有限公司 一种含四氮唑结构的ptp1b衍生物、其制备方法及用途
WO2016142950A1 (fr) * 2015-03-11 2016-09-15 Harman Finochem Limited Nouveau procédé de préparation de (2s,3r,4r,5s,6r)-2-{3-[5-[4-fluoro-phényl)-thiophén-2-ylméthyl]-4-méthyl-phényl}-6-hydroxyméthyl-tétrahydro-pyran-3,4,5-triol et de sa forme semi-hydratée amorphe stable
CA2986697C (fr) 2015-05-22 2023-09-26 Janssen Pharmaceutica Nv Forme cristalline anhydre de (1s)-1,5-anhydro-1-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-d-glucitol
CN104926803B (zh) * 2015-06-17 2017-12-22 南通常佑药业科技有限公司 一种新的sglt2抑制剂药物的制备方法
CZ2015435A3 (cs) 2015-06-25 2017-01-04 Zentiva, K.S. Pevné formy amorfního canagliflozinu
CN104987320A (zh) * 2015-08-03 2015-10-21 沧州那瑞化学科技有限公司 一种坎格列净中间体的制备方法
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
EP3349762B1 (fr) 2015-09-15 2021-08-25 Laurus Labs Limited Co-cristaux d'inhibiteurs de sglt2, procédé pour leur préparation et compositions pharmaceutiques de ceux-ci
WO2017046655A1 (fr) * 2015-09-16 2017-03-23 Optimus Drugs (P) Ltd Nouveau procédé de préparation de canagliflozine
US10370365B2 (en) 2015-09-16 2019-08-06 Optimus Drugs (P) Limited Process for the preparation of Canagliflozin
CZ2015729A3 (cs) 2015-10-13 2017-04-26 Zentiva, K.S. Příprava intermediátů pro syntézu Canagliflozinu a Dapagliflozinu
WO2017064679A1 (fr) * 2015-10-15 2017-04-20 Lupin Limited Procédé destiné à la préparation de canagliflozine amorphe
CN105503845A (zh) * 2015-12-01 2016-04-20 北京普德康利医药科技发展有限公司 去氟卡格列净化合物及其制备方法和应用
WO2017093949A1 (fr) * 2015-12-04 2017-06-08 Dr. Reddy's Laboratories Limited Canagliflozine sensiblement pure
CN106892929B (zh) * 2015-12-17 2020-01-14 上海艾力斯医药科技有限公司 螺缩酮衍生物及其制备方法和应用
EP3394051B1 (fr) 2015-12-21 2020-04-22 Janssen Pharmaceutica N.V. Procédure de cristallisation pour l'obtention de cristaux d'hémihydrate canagliflozine
CN105541815B (zh) * 2015-12-24 2018-07-13 寿光富康制药有限公司 一种卡格列净的制备方法
WO2017141202A1 (fr) 2016-02-17 2017-08-24 Lupin Limited Complexe d'inhibiteur sglt2 et son procédé de préparation
ES2898336T3 (es) * 2016-06-17 2022-03-07 Dae Woong Pharma Derivado de difenilmetano en forma cristalina
WO2018020506A1 (fr) 2016-07-25 2018-02-01 Natco Pharma Ltd Processus pour la préparation des formes amorphes de canagliflozine
CA3041169A1 (fr) 2016-10-19 2018-04-26 Boehringer Ingelheim International Gmbh Combinaisons comprenant un inhibiteur de ssao/vap-1 et un inhibiteur de sglt2, leurs utilisations
CN106588898A (zh) 2017-02-20 2017-04-26 浙江华海药业股份有限公司 一种卡格列净无定型的制备方法
US11198703B2 (en) 2017-05-09 2021-12-14 Piramal Enterprises Limited Process for the preparation of SGLT2 inhibitors and intermediates thereof
AU2018283781B2 (en) 2017-06-12 2023-09-28 Janssen Pharmaceutica Nv Method for reducing or preventing cardiovascular events in patients with type II diabetes mellitus
CN108017612B (zh) * 2017-11-29 2020-06-09 南通常佑药业科技有限公司 一种坎格列净中间体的制备方法
CN111989103A (zh) 2018-04-17 2020-11-24 勃林格殷格翰国际有限公司 药物组合物、其治疗方法和用途
MX2021000601A (es) 2018-07-19 2021-04-13 Astrazeneca Ab Metodos de tratamiento de hfpef empleando dapagliflozina y composiciones que comprenden la misma.
WO2020039394A1 (fr) 2018-08-24 2020-02-27 Novartis Ag Nouvelles combinaisons de médicaments
WO2020050361A1 (fr) * 2018-09-06 2020-03-12 株式会社トクヤマ PROCÉDÉ DE FABRICATION DE DÉRIVÉ D'ARYLE β－C-GLYCOSIDE
JP7432598B2 (ja) 2018-11-05 2024-02-16 ベタゲノン アーベー 重度のインスリン抵抗性糖尿病の対象における糖尿病の治療方法
TW202103709A (zh) 2019-03-26 2021-02-01 比利時商健生藥品公司 用於治療患有慢性腎臟病之對象的方法
CA3158368A1 (fr) 2019-11-28 2021-06-03 Boehringer Ingelheim Vetmedica Gmbh Utilisation d'inhibiteurs de sglt-2 dans le sechage de mammiferes non humains
CN110981851A (zh) * 2019-12-24 2020-04-10 艾希尔（深圳）药物研发有限公司 一种卡格列净杂质的制备方法
CA3167531A1 (fr) 2020-02-17 2021-08-26 Boehringer Ingelheim Vetmedica Gmbh Utilisation d'inhibiteurs de sglt-2 pour la prevention et/ou le traitement de maladies cardiaques chez les felins
CN115916197A (zh) 2020-04-22 2023-04-04 拜耳公司 用于治疗和/或预防心血管和/或肾脏疾病的非奈利酮和sglt2抑制剂的组合
US20220023252A1 (en) 2020-07-27 2022-01-27 Astrazeneca Ab Methods of treating chronic kidney disease with dapagliflozin
WO2022208172A1 (fr) 2021-04-01 2022-10-06 Astrazeneca Uk Limited Systèmes et méthodes de gestion de prédiabète à l'aide d'une composition pharmaceutique d'inhibiteur de cotransport 2 de sodium-glucose à base de gliflozine
CN113429379A (zh) * 2021-06-28 2021-09-24 江苏法安德医药科技有限公司 一种lh-1801中间体及其制备方法和应用
WO2023006745A1 (fr) 2021-07-28 2023-02-02 Boehringer Ingelheim Vetmedica Gmbh Utilisation d'inhibiteurs de sglt-2 pour la prévention et/ou le traitement de l'hypertension chez des mammifères non humains
KR20240040106A (ko) 2021-07-28 2024-03-27 베링거잉겔하임베트메디카게엠베하 비-사람 포유류에서 신장 질환의 예방 및/또는 치료를 위한 sglt-2 억제제의 용도
WO2023006718A1 (fr) 2021-07-28 2023-02-02 Boehringer Ingelheim Vetmedica Gmbh Utilisation d'inhibiteurs de sglt-2 pour la prévention et/ou le traitement de maladies cardiaques chez des mammifères non humains à l'exclusion de félins, en particulier des canidés
WO2023129595A1 (fr) 2021-12-30 2023-07-06 Newamsterdam Pharma B.V. Combinaison d'obicetrapib et d'inhibiteur de sglt2
WO2023144722A1 (fr) 2022-01-26 2023-08-03 Astrazeneca Ab Dapagliflozine destinée à être utilisée dans le traitement du prédiabète ou pour réduire le risque de développer un diabète de type 2
US20230381101A1 (en) 2022-05-25 2023-11-30 Boehringer Ingelheim Vetmedica Gmbh Aqueous pharmaceutical compositions comprising sglt-2 inhibitors

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1476537A (fr) * 1965-05-10 1967-04-14 Chimetron Sarl Glucosides dérivés du benzimidazole
US4160861A (en) * 1977-10-03 1979-07-10 Merck & Co., Inc. Method for the separation of antibiotic macrolides
US4584369A (en) * 1981-07-31 1986-04-22 Sloan-Kettering Institute For Cancer Research Anti-leukemic beta-glycosyl C-nucleosides
JP2544609B2 (ja) 1986-10-07 1996-10-16 和光純薬工業株式会社 Ｔｃｎｑ錯体
DE68920798T2 (de) 1988-08-19 1995-05-18 Warner Lambert Co Substituierte Dihydroisochinolinone und verwandte Verbindungen als Verstärker der letalen Effekte von Bestrahlung und bestimmten Chemotherapeutika; ausgewählte Verbindungen, Analoga und Verfahren.
HU203896B (en) 1988-10-26 1991-10-28 Biogal Gyogyszergyar Process for producing glycosides of aromatic amines
JPH04253974A (ja) 1991-02-05 1992-09-09 Ishihara Sangyo Kaisha Ltd スルホニル尿素系化合物、それらの製造方法及びそれらを含有する除草剤
US5149838A (en) * 1991-09-20 1992-09-22 Merck & Co., Inc. Intermediates for substituted azetidinones useful as anti-inflammatory and antidegenerative agents
GB9208161D0 (en) 1992-04-14 1992-05-27 Pfizer Ltd Indoles
US5334225A (en) 1992-07-15 1994-08-02 Kao Corporation Keratinous fiber dye composition containing a 2-substituted amino-5-alkylphenol derivative coupler
US5731292A (en) * 1992-11-12 1998-03-24 Tanabe Seiyaku Co., Ltd. Dihydrochalcone derivatives which are hypoglycemic agents
CA2102591C (fr) * 1992-11-12 2000-12-26 Kenji Tsujihara Agent hypoglycemiant
US6297363B1 (en) * 1993-02-12 2001-10-02 Nomura Co., Ltd. Glycoside indoles
US5830873A (en) * 1994-05-11 1998-11-03 Tanabe Seiyaku Co., Ltd. Propiophenone derivative and a process for preparing the same
US5780483A (en) * 1995-02-17 1998-07-14 Smithkline Beecham Corporation IL-8 receptor antagonists
CA2236007A1 (fr) 1995-10-31 1997-07-17 Gerald Floyd Smith Diamines antithrombotiques
JP3059088B2 (ja) * 1995-11-07 2000-07-04 田辺製薬株式会社 プロピオフェノン誘導体およびその製法
JPH09263549A (ja) 1996-01-25 1997-10-07 Fujisawa Pharmaceut Co Ltd ベンゼン誘導体の製造法
EP0850948B1 (fr) * 1996-12-26 2002-04-24 Tanabe Seiyaku Co., Ltd. Dérivés de propiophénone et un procédé pour leur préparation
US6153632A (en) * 1997-02-24 2000-11-28 Rieveley; Robert B. Method and composition for the treatment of diabetes
JPH10324632A (ja) 1997-03-25 1998-12-08 Takeda Chem Ind Ltd 医薬組成物
JP2000034239A (ja) 1998-07-16 2000-02-02 Asahi Glass Co Ltd トリフルオロメチル化芳香族化合物の製造方法
JP3857429B2 (ja) 1998-07-17 2006-12-13 ポーラ化成工業株式会社 含硫黄抗真菌剤
US20020032164A1 (en) * 1998-12-30 2002-03-14 Dale Roderic M. K. Antimicrobial compounds and methods for their use
GB9912961D0 (en) 1999-06-03 1999-08-04 Pfizer Ltd Metalloprotease inhibitors
US6515117B2 (en) 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
PH12000002657B1 (en) * 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
JP4456768B2 (ja) 2000-02-02 2010-04-28 壽製薬株式会社 Ｃ−配糖体を含有する薬剤
US6627611B2 (en) * 2000-02-02 2003-09-30 Kotobuki Pharmaceutical Co Ltd C-glycosides and preparation of thereof as antidiabetic agents
AU2001232175B2 (en) 2000-03-03 2005-07-07 Pfizer Products Inc. Pyrazole ether derivatives as anti-inflammatory/analgesic agents
HUP0300057A3 (en) * 2000-03-17 2003-09-29 Kissei Pharmaceutical Glucopyranosyloxy benzylbenzene derivatives, pharmaceutical compositions containing the same and intermediates for the preparation of the derivatives
US6683056B2 (en) * 2000-03-30 2004-01-27 Bristol-Myers Squibb Company O-aryl glucoside SGLT2 inhibitors and method
US6555519B2 (en) * 2000-03-30 2003-04-29 Bristol-Myers Squibb Company O-glucosylated benzamide SGLT2 inhibitors and method
DE60141156D1 (de) 2000-11-02 2010-03-11 Ajinomoto Kk Neue pyrazolderivate und diese enthaltende mittel gegen diabetes
US6476352B2 (en) * 2000-12-18 2002-11-05 General Electric Company Laser beam stop sensor and method for automatically detecting the presence of laser beam stop material using a laser beam stop sensor
JP4035052B2 (ja) * 2000-12-28 2008-01-16 キッセイ薬品工業株式会社 グルコピラノシルオキシピラゾール誘導体及びその医薬用途
US7087579B2 (en) * 2001-02-26 2006-08-08 Kissei Pharmaceutical Co., Ltd. Glucopyranosyloxypyrazole derivatives and medicinal use thereof
CA2438595C (fr) 2001-02-27 2011-08-09 Kissei Pharmaceutical Co., Ltd. Derives de glycopyranosyloxypyrazole et utilisation medicinale de ceux-ci
US7018610B2 (en) 2001-03-02 2006-03-28 University Of Western Ontario Polymer precursors of radiolabeled compounds, and methods of making and using the same
US6936590B2 (en) * 2001-03-13 2005-08-30 Bristol Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
WO2002083066A2 (fr) * 2001-04-11 2002-10-24 Bristol-Myers Squibb Company Complexes acides amines de glugocides c-aryle pour le traitement du diabete et procede correspondant
CA2445346C (fr) 2001-04-27 2010-04-06 Ajinomoto Co., Inc. Derives pyrazolyl-o-glycoside n-substitues et medicament contre le diabete en contenant
GB0112122D0 (en) 2001-05-18 2001-07-11 Lilly Co Eli Heteroaryloxy 3-substituted propanamines
KR100882179B1 (ko) 2001-06-20 2009-02-06 깃세이 야쿠힌 고교 가부시키가이샤 함질소 복소환 유도체, 그것을 함유하는 의약 조성물, 그의약 용도 및 그 제조 중간체
JP4115105B2 (ja) 2001-07-02 2008-07-09 協和醗酵工業株式会社 ピラゾール誘導体
WO2003011880A1 (fr) 2001-07-31 2003-02-13 Kissei Pharmaceutical Co., Ltd. Derive de glucopyranosyloxybenzylbenzene, composition medicinale contenant ce derive, usage medicinal de cette composition et produit intermediaire pour produire cette composition
EP1432720A1 (fr) * 2001-09-05 2004-06-30 Bristol-Myers Squibb Company Inhibiteurs de sglt2 contenant du glucoside de o-pyrazole et methode d'utilisation
ATE316148T1 (de) * 2001-10-24 2006-02-15 Michael Burton Enzymsubstrate zum nachweis der beta-d- ribofuranosidase aktivität
BR0214208A (pt) 2001-11-16 2004-10-26 Cutanix Corp Composições farmacêuticas e cosméticas que contêm aldeìdos aromáticos que suportam grupos de oxigênio
US6617313B1 (en) * 2002-03-13 2003-09-09 Council Of Scientific And Industrial Research Glucopyranoside and process of isolation thereof from pterocarpus marsupium pharmaceutical composition containing the same and use thereof
US6562791B1 (en) * 2002-03-29 2003-05-13 Council Of Scientific And Industrial Research Glucopyranoside, process for isolation thereof, pharmaceutical composition containing same and use thereof
CA2482313A1 (fr) 2002-04-18 2003-10-23 Astrazeneca Ab Composes heterocycliques
DE10230605A1 (de) 2002-07-08 2004-01-29 Bayer Ag Substituierte Imidazotriazine
DE10231370B4 (de) 2002-07-11 2006-04-06 Sanofi-Aventis Deutschland Gmbh Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
TWI254635B (en) 2002-08-05 2006-05-11 Yamanouchi Pharma Co Ltd Azulene derivative and salt thereof
AU2003254904A1 (en) 2002-08-09 2004-02-25 Taisho Pharmaceutical Co., Ltd. Aryl 5-thio-beta-d-glucopyranoside derivatives and therapeutic agents for diabetes containing the same
AU2003262262A1 (en) 2002-08-27 2004-03-19 Kissei Pharmaceutical Co., Ltd. Pyrazole derivatives, medicinal composition containing the same, and medicinal use thereof
DE10258008B4 (de) 2002-12-12 2006-02-02 Sanofi-Aventis Deutschland Gmbh Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
DE10258007B4 (de) * 2002-12-12 2006-02-09 Sanofi-Aventis Deutschland Gmbh Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
JP2006516257A (ja) 2003-01-03 2006-06-29 ブリストル−マイヤーズ　スクイブ　カンパニー Ｃ−アリールグルコシドｓｇｌｔ２阻害剤の製造法
PT1980560E (pt) * 2003-03-14 2011-06-29 Astellas Pharma Inc Derivados de c-glicósido para o tratamento da diabetes
JP2004300102A (ja) 2003-03-31 2004-10-28 Kissei Pharmaceut Co Ltd 縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途
AU2003902263A0 (en) 2003-05-12 2003-05-29 Fujisawa Pharmaceutical Co., Ltd. Monosaccharide compounds
WO2004113359A1 (fr) 2003-06-20 2004-12-29 Kissei Pharmaceutical Co., Ltd. Derive de pyrazole, composition de medicaments contenant ledit derive et intermediaire de production associe
WO2005011592A2 (fr) * 2003-08-01 2005-02-10 Janssen Pharmaceutica N.V. Indazoles-o-glucosides substitues
AR048376A1 (es) * 2003-08-01 2006-04-26 Janssen Pharmaceutica Nv C- glicosidos heterociclos fusionados sustituidos
UA86042C2 (en) * 2003-08-01 2009-03-25 Янссен Фармацевтика Н.В. Substituted indazole-o-glucosides
CA2549022A1 (fr) * 2003-08-01 2005-02-10 Janssen Pharmaceutica N.V. Benzimidazole-, benztriazole- et benzimidazolone-o-glucosides substitues
EA010422B1 (ru) * 2003-08-01 2008-08-29 Янссен Фармацевтика Н.В. Замещённые индол-о-глюкозиды
EP2514756B1 (fr) † 2003-08-01 2014-12-17 Mitsubishi Tanabe Pharma Corporation Nouveaux composés présentant une activité inhibitrice contre le transporteur dépendant du sodium

Also Published As

Publication number Publication date
IL206831A (en) 2012-06-28
HRP20130124T1 (hr) 2013-04-30
EA200600351A1 (ru) 2006-08-25
AU2004260761A1 (en) 2005-02-10
EP2514756A1 (fr) 2012-10-24
JP5065135B2 (ja) 2012-10-31
SI1651658T2 (sl) 2020-12-31
SI2896397T1 (en) 2018-01-31
BRPI0413232A (pt) 2006-10-03
ES2844401T3 (es) 2021-07-22
CY1119814T1 (el) 2018-06-27
SI1651658T1 (sl) 2013-04-30
EP1651658B2 (fr) 2020-08-12
PL2896397T5 (pl) 2023-06-19
HRP20130124T4 (hr) 2020-11-13
LU92426I2 (fr) 2014-06-10
BE2014C027I2 (fr) 2023-12-14
CN103214471B (zh) 2018-02-06
TWI385177B (zh) 2013-02-11
US8222219B2 (en) 2012-07-17
US7943788B2 (en) 2011-05-17
ZA200603879B (en) 2010-01-27
EA200800924A1 (ru) 2008-08-29
NO334706B1 (no) 2014-05-12
ZA200601685B (en) 2007-05-30
HRP20171838T4 (hr) 2021-02-05
PL1651658T3 (pl) 2013-05-31
CA2534024C (fr) 2009-06-02
NO20120585L (no) 2006-05-02
CY2014016I2 (el) 2015-12-09
ES2402098T3 (es) 2013-04-26
NO2014009I1 (no) 2014-06-02
US8202984B2 (en) 2012-06-19
US20110105424A1 (en) 2011-05-05
BRPI0413232B1 (pt) 2018-03-06
BRPI0413232B8 (pt) 2021-05-25
PT1651658E (pt) 2013-03-07
SI2896397T2 (sl) 2020-12-31
CA2534024A1 (fr) 2005-02-10
IL173050A0 (en) 2006-06-11
MXPA06001274A (es) 2006-04-11
NO333933B1 (no) 2013-10-28
UA83243C2 (ru) 2008-06-25
MY143203A (en) 2011-03-31
US20120058941A1 (en) 2012-03-08
TWI365190B (en) 2012-06-01
HUE037320T2 (hu) 2018-08-28
NZ545304A (en) 2009-04-30
AU2004260761B2 (en) 2008-01-31
PL1651658T5 (pl) 2020-11-30
EA015104B1 (ru) 2011-06-30
EP2896397B2 (fr) 2020-10-07
JP4130466B2 (ja) 2008-08-06
IL173050A (en) 2011-06-30
CY1113813T1 (el) 2015-12-09
AR045173A1 (es) 2005-10-19
ES2402098T5 (es) 2021-06-09
DK1651658T4 (da) 2020-11-09
HRP20171838T1 (hr) 2018-01-12
KR100942622B1 (ko) 2010-02-17
HK1086277A1 (en) 2006-09-15
MEP61208A (en) 2011-05-10
NO2014009I2 (no) 2016-08-01
KR100778988B1 (ko) 2007-11-28
KR20070065454A (ko) 2007-06-22
CY2014016I1 (el) 2015-12-09
IL206831A0 (en) 2011-08-01
EP3251679B1 (fr) 2020-12-16
ZA200603882B (en) 2010-03-31
EP2514756B1 (fr) 2014-12-17
LT2896397T (lt) 2017-11-27
DK2896397T3 (da) 2017-11-06
NZ575711A (en) 2010-05-28
EP3251679A1 (fr) 2017-12-06
ZA200700550B (en) 2009-08-26
ES2649737T5 (es) 2021-07-07
CR11263A (es) 2010-05-19
TW201038588A (en) 2010-11-01
DK2896397T4 (da) 2020-11-16
HUS1400021I1 (hu) 2016-08-29
CN103819465A (zh) 2014-05-28
EP1651658B1 (fr) 2013-01-16
PL2896397T3 (pl) 2018-03-30
NL300670I2 (fr) 2016-09-22
NO20060220L (no) 2006-05-02
FR14C0034I2 (fr) 2014-11-14
JP2007518683A (ja) 2007-07-12
US20050233988A1 (en) 2005-10-20
DK1651658T3 (da) 2013-02-18
CN103214471A (zh) 2013-07-24
RS53365B (sr) 2014-10-31
JP2008266328A (ja) 2008-11-06
ME00411B (me) 2011-10-10
SG145694A1 (en) 2008-09-29
ES2531660T3 (es) 2015-03-18
CR8188A (es) 2006-07-14
EP2896397A1 (fr) 2015-07-22
EA010299B1 (ru) 2008-08-29
CN104109155A (zh) 2014-10-22
ZA200603881B (en) 2010-01-27
EP2896397B1 (fr) 2017-09-06
ES2649737T3 (es) 2018-01-15
EP1651658A1 (fr) 2006-05-03
CN1829729A (zh) 2006-09-06
RS20060079A (en) 2008-04-04
PT2896397T (pt) 2017-11-23
KR20060057589A (ko) 2006-05-26
TW200510441A (en) 2005-03-16
WO2005012326A1 (fr) 2005-02-10
LU92426I9 (fr) 2019-01-16

Similar Documents

Publication Publication Date Title
FR14C0034I1 (fr)
BE2011C030I2 (fr)
JP2003299673A5 (fr)
JP2003273409A5 (fr)
JP2004063471A5 (fr)
IN2005DE04524A (fr)
JP2004162685A5 (fr)
BE2012C053I2 (fr)
JP2003299632A5 (fr)
JP2004174248A5 (fr)
JP2003341090A5 (fr)
JP2004048000A5 (fr)
JP2004221534A5 (fr)
ECSDI044955S (fr)
JP2004191034A5 (fr)
JP2004111914A5 (fr)
JP2004229074A5 (fr)
AU2002331433A1 (fr)
AU2002318342A1 (fr)
AU2002339901A1 (fr)
AU2002337949A1 (fr)
AU2002333044A1 (fr)
AU2002332887A1 (fr)
AU2002348177A1 (fr)
AU2002311957A1 (fr)