|
WO1997046584A1
(de)
*
|
1996-06-05 |
1997-12-11 |
Boehringer Mannheim Gmbh |
Exendin-analoga, verfahren zu deren herstellung und diese enthaltende arzneimittel
|
|
ATE493998T1
(de)
|
1996-08-08 |
2011-01-15 |
Amylin Pharmaceuticals Inc |
Pharmazeutische zusammensetzung mit einem exendin-4-peptid
|
|
DE69732572T2
(de)
*
|
1996-11-12 |
2005-12-29 |
Novo Nordisk A/S |
Verwendung von glp-1 peptiden
|
|
DE122007000044I2
(de)
|
1997-01-07 |
2011-05-05 |
Amylin Pharmaceuticals Inc |
Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme
|
|
US20040022807A1
(en)
*
|
1998-06-05 |
2004-02-05 |
Duft Bradford J |
Methods for treating obesity
|
|
US7910548B2
(en)
*
|
1997-06-06 |
2011-03-22 |
Amylin Pharmaceuticals, Inc. |
Methods for treating obesity
|
|
EP1938831A1
(en)
*
|
1997-08-08 |
2008-07-02 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
ES2293688T5
(es)
*
|
1997-08-08 |
2011-05-04 |
Amylin Pharmaceuticals, Inc. |
Nuevos compuestos análogos de la exendina.
|
|
US7157555B1
(en)
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
US7223725B1
(en)
*
|
1997-11-14 |
2007-05-29 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
ATE383867T1
(de)
*
|
1997-11-14 |
2008-02-15 |
Amylin Pharmaceuticals Inc |
Neuartige exendin agonisten
|
|
AU2003200129B2
(en)
*
|
1997-11-14 |
2006-06-22 |
Amylin Pharmaceuticals, Llc |
Novel Exendin Agonist Compounds
|
|
AU2006225176B2
(en)
*
|
1997-11-14 |
2009-01-08 |
Amylin Pharmaceuticals, Llc |
Novel exendin agonist compounds
|
|
US7220721B1
(en)
|
1997-11-14 |
2007-05-22 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist peptides
|
|
MXPA00004670A
(es)
|
1997-11-14 |
2003-07-14 |
Amylin Pharmaceuticals Inc |
Compuestos agonistas de exendina novedosos.
|
|
EP1941900A1
(en)
*
|
1997-11-14 |
2008-07-09 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
EP1938830A1
(en)
*
|
1997-11-14 |
2008-07-02 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
US6998387B1
(en)
|
1998-03-19 |
2006-02-14 |
Amylin Pharmaceuticals, Inc. |
Human appetite control by glucagon-like peptide receptor binding compounds
|
|
US7259136B2
(en)
|
1999-04-30 |
2007-08-21 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treating peripheral vascular disease
|
|
US6429197B1
(en)
|
1998-10-08 |
2002-08-06 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain
|
|
US6284725B1
(en)
*
|
1998-10-08 |
2001-09-04 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
|
|
US7399489B2
(en)
|
1999-01-14 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Exendin analog formulations
|
|
US20030087820A1
(en)
*
|
1999-01-14 |
2003-05-08 |
Young Andrew A. |
Novel exendin agonist formulations and methods of administration thereof
|
|
US6902744B1
(en)
*
|
1999-01-14 |
2005-06-07 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist formulations and methods of administration thereof
|
|
ES2278589T3
(es)
|
1999-01-14 |
2007-08-16 |
Amylin Pharmaceuticals, Inc. |
Excendinas destinadas a la inhibicion de glucagon.
|
|
US20050272652A1
(en)
|
1999-03-29 |
2005-12-08 |
Gault Victor A |
Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
|
|
CA2372214A1
(en)
|
1999-04-30 |
2000-11-09 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US6924264B1
(en)
*
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US20090175821A1
(en)
*
|
1999-05-17 |
2009-07-09 |
Bridon Dominique P |
Modified therapeutic peptides with extended half-lives in vivo
|
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
US6506724B1
(en)
|
1999-06-01 |
2003-01-14 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
EP1076066A1
(en)
*
|
1999-07-12 |
2001-02-14 |
Zealand Pharmaceuticals A/S |
Peptides for lowering blood glucose levels
|
|
WO2001051078A1
(en)
*
|
2000-01-10 |
2001-07-19 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for modulation of triglyceride levels and treatment of dyslipidemia
|
|
ES2253353T3
(es)
*
|
2000-03-08 |
2006-06-01 |
Novo Nordisk A/S |
Reduccion del colesterol serico.
|
|
EP2123293A3
(en)
|
2000-12-14 |
2010-09-08 |
Amylin Pharmaceuticals, Inc. |
Peptide YY and petide YY agonists for treatment of metabolic disorders
|
|
US20090281032A1
(en)
*
|
2001-03-01 |
2009-11-12 |
Peter Raymond Flatt |
Modified CCK peptides
|
|
ATE408414T1
(de)
|
2001-07-31 |
2008-10-15 |
Us Gov Health & Human Serv |
Glp 1 exendin 4 peptidanaloga und deren verwendungen
|
|
GB0121709D0
(en)
*
|
2001-09-07 |
2001-10-31 |
Imp College Innovations Ltd |
Food inhibition agent
|
|
CN100350968C
(zh)
*
|
2001-09-24 |
2007-11-28 |
皇家创新有限公司 |
饮食行为的改进
|
|
WO2003059378A2
(en)
*
|
2001-12-29 |
2003-07-24 |
Novo Nordisk A/S |
Combined use of a glp-1 compound and another drug for treating dyslipidemia
|
|
ATE412421T1
(de)
*
|
2002-01-08 |
2008-11-15 |
Amylin Pharmaceuticals Inc |
Verwendung von amylin, amylinanaloga und amylin derivaten zur behandlung von dyslipidämie und hypertriglyceridämie
|
|
EP1474163A2
(en)
*
|
2002-01-10 |
2004-11-10 |
Imperial College Innovations Limited |
Modification of feeding behavior
|
|
US8058233B2
(en)
*
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
US7105489B2
(en)
*
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
WO2004005342A1
(en)
|
2002-07-04 |
2004-01-15 |
Zealand Pharma A/S |
Glp-1 and methods for treating diabetes
|
|
BR0314996A
(pt)
|
2002-10-02 |
2005-08-09 |
Zealand Pharma As |
Composição, composição farmaceuticamente aceitável, método para produzir a composição, métodos para estabilizar a exendina-4 (1-39) ou uma sua variante, derivado ou análogo contra a degradação, antes, durante ou após o uso pretendido, para tratar doenças, para tratar de estados de doenças associados com nìveis elevados de glicose do sangue, para a regulação dos nìveis de glicose do sangue, para a regulação do esvaziamento gástrico, para estimular a liberação de insulina em um mamìfero para reduzir o nìvel de glicose do sangue em um mamìfero, para reduzir o nìvel de lipìdeos plasmáticos em um mamìfero, para reduzir a mortalidade e a morbidez após o infarto miocárdico em um mamìfero, para estimular a liberação de insulina em um mamìfero, e para produzir uma exendina (1-39) estabilizada, e, exendina (1-39) estabilizada
|
|
WO2004035762A2
(en)
*
|
2002-10-17 |
2004-04-29 |
Alkermes Controlled Therapeutics, Inc. Ii |
Microencapsulation and sustained release of biologically active polypeptides
|
|
AU2003283004A1
(en)
*
|
2002-10-22 |
2004-05-13 |
Waratah Pharmaceuticals, Inc. |
Treatment of diabetes
|
|
WO2004050115A2
(en)
*
|
2002-12-03 |
2004-06-17 |
Novo Nordisk A/S |
Combination treatment using exendin-4 and thiazolidinediones
|
|
EP1581247A4
(en)
*
|
2002-12-11 |
2007-09-12 |
Amylin Pharmaceuticals Inc |
METHODS AND COMPOSITIONS FOR TREATING STEIN-LEVENTHAL SYNDROME
|
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
|
US20040209803A1
(en)
*
|
2002-12-19 |
2004-10-21 |
Alain Baron |
Compositions for the treatment and prevention of nephropathy
|
|
US7731947B2
(en)
|
2003-11-17 |
2010-06-08 |
Intarcia Therapeutics, Inc. |
Composition and dosage form comprising an interferon particle formulation and suspending vehicle
|
|
GB0300571D0
(en)
*
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
EP1631308B1
(en)
*
|
2003-05-30 |
2013-07-31 |
Amylin Pharmaceuticals, LLC |
Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
|
|
EP1663289A2
(en)
*
|
2003-08-29 |
2006-06-07 |
Amylin Pharmaceuticals, Inc. |
Methods for treating or ameliorating ghrelin-associated diseases and disorders
|
|
KR101135244B1
(ko)
|
2007-11-29 |
2012-04-24 |
한미사이언스 주식회사 |
인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
ES2373660T3
(es)
*
|
2003-11-13 |
2012-02-07 |
Novo Nordisk A/S |
Composición farmacéutica que comprende un análogo insulinotrópico de glp-1 (7-37), insulina asp(b28) y un tensioactivo.
|
|
US8263084B2
(en)
*
|
2003-11-13 |
2012-09-11 |
Hanmi Science Co., Ltd |
Pharmaceutical composition for treating obesity-related disease comprising insulinotropic peptide conjugate
|
|
DK3300721T4
(da)
|
2003-11-20 |
2025-03-03 |
Novo Nordisk As |
Propylenglycol-holdige peptidformuleringer hvilke er optimale til fremstilling og til anvendelse i injektionsindretninger
|
|
EP2298337B1
(en)
*
|
2003-12-09 |
2017-02-22 |
Novo Nordisk A/S |
Regulation of food preference using GLP-1 agonists
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
ATE471340T1
(de)
|
2004-02-11 |
2010-07-15 |
Amylin Pharmaceuticals Inc |
Peptide der amylin familie, verfahren zu deren herstellung und verwendung
|
|
NZ579621A
(en)
*
|
2004-02-11 |
2011-03-31 |
Amylin Pharmaceuticals Inc |
Hybrid polypeptides with selectable properties
|
|
HRP20060362A2
(en)
*
|
2004-04-23 |
2007-03-31 |
Conjuchem Biotechnologies Inc. |
Method for the purification of albumin conjugates
|
|
US20090069226A1
(en)
*
|
2004-05-28 |
2009-03-12 |
Amylin Pharmaceuticals, Inc. |
Transmucosal delivery of peptides and proteins
|
|
EP1758575A1
(en)
*
|
2004-06-11 |
2007-03-07 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using glp-1 agonists
|
|
AU2005305036B2
(en)
*
|
2004-11-01 |
2011-03-10 |
Amylin Pharmaceuticals, Llc |
Treatment of obesity and related disorders
|
|
US8394765B2
(en)
|
2004-11-01 |
2013-03-12 |
Amylin Pharmaceuticals Llc |
Methods of treating obesity with two different anti-obesity agents
|
|
WO2007055728A1
(en)
*
|
2005-11-01 |
2007-05-18 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
|
CN101094689B
(zh)
|
2004-11-01 |
2013-06-12 |
安米林药品有限责任公司 |
治疗肥胖以及肥胖相关疾病和病症的方法
|
|
EP1841448A2
(en)
*
|
2004-12-30 |
2007-10-10 |
Diakine Therapeutics, Inc. |
Pharmaceutical compositions and methods for restoring beta-cell mass and function
|
|
WO2006083761A2
(en)
|
2005-02-03 |
2006-08-10 |
Alza Corporation |
Solvent/polymer solutions as suspension vehicles
|
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
|
KR20070115947A
(ko)
|
2005-02-11 |
2007-12-06 |
아밀린 파마슈티칼스, 인크. |
선택가능한 특성들을 가지는 gip 유사체 및 하이브리드폴리펩타이드
|
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
|
WO2007022123A2
(en)
*
|
2005-08-11 |
2007-02-22 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
|
US7759312B2
(en)
*
|
2005-03-11 |
2010-07-20 |
Endo Pharmaceuticals Solutions Inc. |
Delivery of dry formulations of octreotide
|
|
CN101193626A
(zh)
*
|
2005-03-11 |
2008-06-04 |
益德威士医药股份有限公司 |
奥曲肽的受控释放制剂
|
|
CN102343084A
(zh)
|
2005-03-31 |
2012-02-08 |
安米林药品公司 |
用于治疗精神病和精神障碍的胰淀素和胰淀素激动剂
|
|
GB0511986D0
(en)
*
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
|
PL1971362T3
(pl)
|
2005-08-19 |
2015-05-29 |
Amylin Pharmaceuticals Llc |
Eksendyna do leczenia cukrzycy i zmniejszania masy ciała
|
|
US8389472B2
(en)
|
2005-08-19 |
2013-03-05 |
Amylin Pharmaceuticals, Llc |
Exendin-4 to treat nonalcoholic steatohepatitis and nonalcoholic fatty liver disease
|
|
JP2009512715A
(ja)
|
2005-10-21 |
2009-03-26 |
ノバルティス アクチエンゲゼルシャフト |
レニン阻害剤と抗異脂肪血症剤および/または抗肥満症剤の組み合わせ
|
|
WO2007055743A2
(en)
*
|
2005-11-01 |
2007-05-18 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
|
US8039432B2
(en)
*
|
2005-11-09 |
2011-10-18 |
Conjuchem, Llc |
Method of treatment of diabetes and/or obesity with reduced nausea side effect
|
|
JP4757311B2
(ja)
*
|
2005-11-29 |
2011-08-24 |
コーロン インダストリーズ インク |
編物により補強された複合中空繊維膜
|
|
CN101384623B
(zh)
*
|
2005-12-22 |
2013-07-24 |
常山凯捷健生物药物研发(河北)有限公司 |
白蛋白与治疗剂的预成型偶联物的制备方法
|
|
WO2007139941A2
(en)
*
|
2006-05-26 |
2007-12-06 |
Amylin Pharmaceuticals, Inc. |
Composition and methods for treatment of congestive heart failure
|
|
KR101106510B1
(ko)
|
2006-05-30 |
2012-01-20 |
인타르시아 세라퓨틱스 인코포레이티드 |
투피스, 내부채널 삼투압 전달 시스템 유동 조절기
|
|
CN101511868B
(zh)
|
2006-07-24 |
2013-03-06 |
比奥雷克西斯制药公司 |
毒蜥外泌肽融合蛋白
|
|
US8501693B2
(en)
*
|
2006-08-04 |
2013-08-06 |
Amylin Pharmaceuticals, Llc |
Use of exendins and exendin agonists and GLP-1 receptor agonists for altering the concentration of fibrinogen
|
|
WO2008019143A2
(en)
*
|
2006-08-04 |
2008-02-14 |
Amylin Pharmaceuticals, Inc |
Use of exendins and glp-i receptor agonists for altering lipoprotein particle size and subclass composition
|
|
EP2359808B1
(en)
|
2006-08-09 |
2013-05-22 |
Intarcia Therapeutics, Inc |
Osmotic delivery systems and piston assemblies
|
|
WO2008022267A2
(en)
*
|
2006-08-17 |
2008-02-21 |
Wellstat Therapeutics Corporation |
Combination treatment for metabolic disorders
|
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
|
WO2008023050A1
(en)
|
2006-08-25 |
2008-02-28 |
Novo Nordisk A/S |
Acylated exendin-4 compounds
|
|
KR100872304B1
(ko)
*
|
2006-11-28 |
2008-12-05 |
주식회사 코오롱 |
편물로 보강된 복합 중공사막
|
|
TWI428346B
(zh)
*
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
RU2413528C2
(ru)
|
2007-01-18 |
2011-03-10 |
Открытое Акционерное Общество "Валента Фармацевтика" |
Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
|
|
WO2008133908A2
(en)
*
|
2007-04-23 |
2008-11-06 |
Intarcia Therapeutics, Inc. |
Suspension formulations of insulinotropic peptides and uses thereof
|
|
JP2009019027A
(ja)
*
|
2007-07-16 |
2009-01-29 |
Hanmi Pharmaceutical Co Ltd |
アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体
|
|
UA97707C2
(ru)
*
|
2007-11-14 |
2012-03-12 |
Амилин Фармасьютикалз, Инк. |
Способы лечения ожирения и заболеваний, расстройств, связанных с ожирением
|
|
JP2011506442A
(ja)
*
|
2007-12-11 |
2011-03-03 |
コンジュケム バイオテクノロジーズ インコーポレイテッド |
インスリン分泌性ペプチド結合体の製剤
|
|
CA2726861C
(en)
|
2008-02-13 |
2014-05-27 |
Intarcia Therapeutics, Inc. |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
|
US20110046071A1
(en)
*
|
2008-03-05 |
2011-02-24 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
GLP-1 Receptor Agonists And Related Active Pharmaceutical Ingredients For Treatment Of Cancer
|
|
WO2009143285A2
(en)
|
2008-05-21 |
2009-11-26 |
Amylin Pharmaceuticals, Inc. |
Exendins to lower cholestrol and triglycerides
|
|
CA2729139C
(en)
|
2008-06-25 |
2016-07-26 |
Endo Pharmaceuticals Solutions Inc. |
Octreotide implant having a release agent
|
|
EP2303226B1
(en)
*
|
2008-06-25 |
2016-03-23 |
Endo Pharmaceuticals Solutions Inc. |
Sustained delivery of exenatide and other polypeptides
|
|
CA2731236A1
(en)
*
|
2008-07-21 |
2010-01-28 |
Transpharma Medical Ltd. |
Transdermal system for extended delivery of incretins and incretin mimetic peptides
|
|
SI2341905T2
(sl)
|
2008-09-04 |
2024-02-29 |
Amylin Pharmaceuticals, Llc |
Formulacije s podaljšanim sproščanjem z uporabo brezvodnih nosilcev
|
|
RS59913B1
(sr)
|
2008-10-17 |
2020-03-31 |
Sanofi Aventis Deutschland |
Kombinacija insulina i glp-1-agonista
|
|
DE102008053048A1
(de)
|
2008-10-24 |
2010-04-29 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102008051834A1
(de)
|
2008-10-17 |
2010-04-22 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102009038210A1
(de)
|
2009-08-20 |
2011-03-03 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
CN101870728A
(zh)
|
2009-04-23 |
2010-10-27 |
派格生物医药(苏州)有限公司 |
新型Exendin变体及其缀合物
|
|
EP2435061A4
(en)
|
2009-05-28 |
2013-03-27 |
Amylin Pharmaceuticals Inc |
DAMPING GLP-1 RECEPTOR AGONIST COMPOUNDS
|
|
CN102596175A
(zh)
|
2009-07-06 |
2012-07-18 |
赛诺菲-安万特德国有限公司 |
含有甲硫氨酸的水性胰岛素制备物
|
|
RU2547990C2
(ru)
|
2009-09-28 |
2015-04-10 |
Интарсия Терапьютикс, Инк. |
Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
|
|
EP2496249B1
(en)
*
|
2009-11-03 |
2016-03-09 |
Amylin Pharmaceuticals, LLC |
Glp-1 receptor agonist for use in treating obstructive sleep apnea
|
|
PT3345593T
(pt)
|
2009-11-13 |
2023-11-27 |
Sanofi Aventis Deutschland |
Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina
|
|
DE102010011919A1
(de)
|
2010-03-18 |
2011-09-22 |
Sanofi-Aventis Deutschland Gmbh |
Pharmazeutische Zusammensetzung umfassend einen GLP-1-Agonisten und Methionin
|
|
MY180661A
(en)
|
2009-11-13 |
2020-12-04 |
Sanofi Aventis Deutschland |
Pharmaceutical composition comprising a glp-1 agonist, an insulin and methionine
|
|
WO2011064316A2
(en)
|
2009-11-25 |
2011-06-03 |
Paolo Botti |
Mucosal delivery of peptides
|
|
CN102100912B
(zh)
*
|
2009-12-16 |
2015-04-22 |
上海蓝心医药科技有限公司 |
一种给药组合物及其制备和使用方法
|
|
WO2011123943A1
(en)
|
2010-04-09 |
2011-10-13 |
Mount Sinai Hospital |
Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
|
|
CN107129538B
(zh)
|
2010-04-27 |
2021-07-16 |
西兰制药公司 |
Glp-1受体激动剂和胃泌素的肽缀合物及其用途
|
|
WO2012027331A1
(en)
|
2010-08-27 |
2012-03-01 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
|
PL2611458T3
(pl)
|
2010-08-30 |
2017-02-28 |
Sanofi-Aventis Deutschland Gmbh |
Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
CA2812951A1
(en)
|
2010-09-28 |
2012-04-19 |
Amylin Pharmaceuticals, Llc |
Engineered polypeptides having enhanced duration of action
|
|
US9161953B2
(en)
|
2010-12-22 |
2015-10-20 |
Amylin Pharmaceuticals, Llc |
GLP-1 receptor agonists for islet cell transplantation
|
|
WO2012097333A2
(en)
|
2011-01-14 |
2012-07-19 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
DK2681236T3
(en)
|
2011-03-01 |
2018-04-16 |
Synergy Pharmaceuticals Inc |
PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
|
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
|
EP2714069A4
(en)
|
2011-05-25 |
2015-06-24 |
Amylin Pharmaceuticals Llc |
LONG-TERM CONJUGATES WITH TWO HORMONES
|
|
JP6007417B2
(ja)
|
2011-05-31 |
2016-10-12 |
レセプトス エルエルシー |
新規glp−1受容体安定剤および調節剤
|
|
WO2013004983A1
(en)
|
2011-07-04 |
2013-01-10 |
Imperial Innovations Limited |
Novel compounds and their effects on feeding behaviour
|
|
JP6006309B2
(ja)
|
2011-07-08 |
2016-10-12 |
アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc |
作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド
|
|
AR087693A1
(es)
|
2011-08-29 |
2014-04-09 |
Sanofi Aventis Deutschland |
Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2
|
|
TWI559929B
(en)
|
2011-09-01 |
2016-12-01 |
Sanofi Aventis Deutschland |
Pharmaceutical composition for use in the treatment of a neurodegenerative disease
|
|
WO2013050378A1
(en)
|
2011-10-04 |
2013-04-11 |
Sanofi-Aventis Deutschland Gmbh |
Glp-1 agonist for use in the treatment of stenosis or/and obstruction in the biliary tract
|
|
PL2763690T3
(pl)
|
2011-10-04 |
2016-04-29 |
Sanofi Aventis Deutschland |
Liksysenatyd do stosowania w leczeniu stenozy i/lub niedrożności w układzie przewodów trzustkowych
|
|
TW201326194A
(zh)
|
2011-11-03 |
2013-07-01 |
Zealand Pharma As |
Glp-1胃泌素受體促效劑肽結合物
|
|
BR112014013925B1
(pt)
|
2011-12-12 |
2022-02-22 |
Receptos Llc |
Compostos moduladores do receptor de glp-1 e composição e combinação farmacêutica compreendendo os ditos compostos
|
|
SG11201407860PA
(en)
|
2012-06-14 |
2014-12-30 |
Sanofi Sa |
Exendin-4 peptide analogues
|
|
IN2015DN00544A
(https=)
|
2012-07-23 |
2015-06-26 |
Zealand Pharma As |
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
AU2013366692B2
(en)
|
2012-12-21 |
2017-11-23 |
Sanofi |
Dual GLP1/GIP or trigonal GLP1/GIP/Glucagon agonists
|
|
KR101581497B1
(ko)
|
2013-01-24 |
2015-12-30 |
강원대학교산학협력단 |
인삼열매 추출물을 포함하는 파킨슨병과 알츠하이머병의 예방 또는 치료용 조성물
|
|
TWI780236B
(zh)
|
2013-02-04 |
2022-10-11 |
法商賽諾菲公司 |
胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
|
|
DK2968471T3
(en)
|
2013-03-01 |
2017-10-23 |
Fundació Hospital Univ Vall D' Hebron - Inst De Recerca |
Peptides for use in the topical treatment of retinal neurodegenerative diseases, especially in early stages of diabetic retinopathy and other retinal diseases in which neurodegeneration plays an essential role
|
|
BR112015030326A2
(pt)
|
2013-06-05 |
2017-08-29 |
Synergy Pharmaceuticals Inc |
Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
|
|
CN109867630A
(zh)
|
2013-06-11 |
2019-06-11 |
赛尔基因第二国际有限公司 |
新型glp-1受体调节剂
|
|
PL3057984T3
(pl)
|
2013-10-17 |
2018-12-31 |
Zealand Pharma A/S |
Acylowane analogi glukagonu
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
RU2016117275A
(ru)
|
2013-11-01 |
2017-12-04 |
Сфериум Биомед С.Л. |
Тельца включения для трансдермальной доставки терапевтических и косметических средств
|
|
CN105829339B
(zh)
|
2013-11-06 |
2021-03-12 |
西兰制药公司 |
胰高血糖素-glp-1-gip三重激动剂化合物
|
|
WO2015067715A2
(en)
|
2013-11-06 |
2015-05-14 |
Zealand Pharma A/S |
Gip-glp-1 dual agonist compounds and methods
|
|
EP3080154B1
(en)
|
2013-12-13 |
2018-02-07 |
Sanofi |
Dual glp-1/gip receptor agonists
|
|
WO2015086733A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/glucagon receptor agonists
|
|
EP3080152A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
WO2015086728A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
|
|
MX2016008978A
(es)
|
2014-01-09 |
2016-10-04 |
Sanofi Sa |
Formulaciones farmaceuticas de analogos de insulina y/o derivados de insulina estabilizadas y que estan libres de glicerol.
|
|
BR112016015851A2
(pt)
|
2014-01-09 |
2017-08-08 |
Sanofi Sa |
Formulações farmacêuticas estabilizadas de insulina aspart
|
|
MX2016008979A
(es)
|
2014-01-09 |
2016-10-04 |
Sanofi Sa |
Formulaciones farmaceuticas estabilizadas de analogos de insulina y/o derivados de insulina.
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自exendin-4之雙重glp-1/升糖素受體促效劑
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
CA2955836C
(en)
|
2014-07-25 |
2023-02-14 |
Celgene International Ii Sarl |
Glp-1 receptor modulators
|
|
RU2573933C1
(ru)
|
2014-08-21 |
2016-01-27 |
Дафот Энтерпрайсис Лимитед |
Пептид для лечения сахарного диабета 2-го типа и его осложнений
|
|
KR102431436B1
(ko)
|
2014-08-29 |
2022-08-10 |
테스 파마 에스.알.엘. |
α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
|
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
|
KR102620911B1
(ko)
|
2014-10-29 |
2024-01-05 |
질랜드 파마 에이/에스 |
Gip 효능제 화합물 및 방법
|
|
ES2844573T3
(es)
|
2014-12-10 |
2021-07-22 |
Receptos Llc |
Moduladores del receptor de GLP-1
|
|
EP3229828B1
(en)
|
2014-12-12 |
2023-04-05 |
Sanofi-Aventis Deutschland GmbH |
Insulin glargine/lixisenatide fixed ratio formulation
|
|
EA201791982A1
(ru)
|
2015-03-09 |
2020-02-17 |
Интекрин Терапьютикс, Инк. |
Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
|
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
|
DK3283507T3
(da)
|
2015-04-16 |
2020-01-02 |
Zealand Pharma As |
Acyleret glucagonanalog
|
|
LT3297653T
(lt)
|
2015-05-22 |
2022-01-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Postbariatrinės hipoglikemijos gydymas glp-1 antagonistais
|
|
RU2730996C2
(ru)
|
2015-06-03 |
2020-08-26 |
Интарсия Терапьютикс, Инк. |
Системы установки и извлечения имплантата
|
|
AR105319A1
(es)
|
2015-06-05 |
2017-09-27 |
Sanofi Sa |
Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
|
|
TW201706291A
(zh)
|
2015-07-10 |
2017-02-16 |
賽諾菲公司 |
作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物
|
|
US10677956B2
(en)
*
|
2015-10-01 |
2020-06-09 |
Schlumberger Technology Corporation |
Active damping for NMR logging tools
|
|
CA3001065A1
(en)
|
2015-10-14 |
2017-04-20 |
Xiaoxi WEI |
Compositions and methods for reducing ice crystal formation
|
|
UA127495C2
(uk)
|
2015-12-23 |
2023-09-13 |
Амджен Інк. |
Виділений антигензв'язуючий білок, який специфічно зв'язується з поліпептидом рецептора шлункового інгібіторного пептиду (gipr) людини, та фармацевтична композиція, яка його містить
|
|
US10653753B2
(en)
|
2016-03-04 |
2020-05-19 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hyperinsulinemic hypoglycemia with exendin-4 derivatives
|
|
US11207415B2
(en)
|
2016-04-15 |
2021-12-28 |
Syracuse University |
Peptide drug improvement using vitamin B12 and haptocorrin binding substrate conjugates
|
|
JP2019515677A
(ja)
|
2016-04-26 |
2019-06-13 |
アール.ピー.シェーラー テクノロジーズ エルエルシー |
抗体複合体ならびにそれを作製および使用する方法
|
|
KR102574993B1
(ko)
|
2016-05-16 |
2023-09-06 |
인타르시아 세라퓨틱스 인코포레이티드 |
글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
|
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
|
EP3515408A1
(en)
|
2016-09-23 |
2019-07-31 |
Delpor, Inc. |
Stable compositions for incretin mimetic compounds
|
|
WO2018069532A1
(en)
|
2016-10-14 |
2018-04-19 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
|
LT3541366T
(lt)
|
2016-11-21 |
2025-03-10 |
Amylyx Pharmaceuticals, Inc. |
Eksendino (9-39) buferiniai preparatai
|
|
US11285180B2
(en)
|
2016-12-06 |
2022-03-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods of enhancing the potency of incretin-based drugs in subjects in need thereof
|
|
EP3551651B1
(en)
|
2016-12-09 |
2024-03-06 |
Zealand Pharma A/S |
Acylated glp-1/glp-2 dual agonists
|
|
JP7286542B2
(ja)
|
2017-01-03 |
2023-06-05 |
インターシア セラピューティクス,インコーポレイティド |
Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
|
|
IL313587A
(en)
|
2017-01-17 |
2024-08-01 |
Amgen Inc |
Method of treating or ameliorating metabolic disorders using glp-1 receptor agonists conjugated to antagonists for gastric inhibitory peptide receptor (gipr)
|
|
JP2020515639A
(ja)
|
2017-04-03 |
2020-05-28 |
コヒラス・バイオサイエンシズ・インコーポレイテッド |
進行性核上性麻痺の処置のためのPPARγアゴニスト
|
|
EA201992502A1
(ru)
|
2017-06-20 |
2020-04-22 |
Эмджен Инк. |
Способ лечения или уменьшения интенсивности метаболических нарушений с применением белков, связывающих рецептор гастроингибиторного пептида (gipr), в комбинации с агонистами glp-1
|
|
EP3642238A1
(en)
|
2017-06-21 |
2020-04-29 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using antagonistic binding proteins for gastric inhibitory peptide receptor (gipr)/glp-1 receptor agonist fusion proteins
|
|
KR102665710B1
(ko)
|
2017-08-24 |
2024-05-14 |
노보 노르디스크 에이/에스 |
Glp-1 조성물 및 그 용도
|
|
KR102727918B1
(ko)
|
2018-04-10 |
2024-11-11 |
사노피-아벤티스 도이칠란트 게엠베하 |
캡핑을 사용한 릭시세나티드 합성
|
|
SG11202010017SA
(en)
|
2018-04-10 |
2020-11-27 |
Sanofi Aventis Deutschland |
Method for cleavage of solid phase-bound peptides from the solid phase
|
|
AR117122A1
(es)
|
2018-11-20 |
2021-07-14 |
Tes Pharma S R L |
INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA
|
|
WO2020185533A1
(en)
|
2019-03-08 |
2020-09-17 |
Amgen Inc. |
Growth differentiation factor 15 combination therapy
|
|
JP7761567B2
(ja)
|
2020-02-18 |
2025-10-28 |
ノヴォ ノルディスク アー/エス |
医薬製剤
|
|
WO2024123812A1
(en)
|
2022-12-05 |
2024-06-13 |
Shattuck Labs, Inc. |
Fusion proteins for the treatment of cardiometabolic diseases
|