ES2593256T3 - Compuestos químicos, composiciones y métodos para las modulaciones de cinasas - Google Patents
Compuestos químicos, composiciones y métodos para las modulaciones de cinasas Download PDFInfo
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- ES2593256T3 ES2593256T3 ES11784354.0T ES11784354T ES2593256T3 ES 2593256 T3 ES2593256 T3 ES 2593256T3 ES 11784354 T ES11784354 T ES 11784354T ES 2593256 T3 ES2593256 T3 ES 2593256T3
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
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- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
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- C—CHEMISTRY; METALLURGY
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- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
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- C07—ORGANIC CHEMISTRY
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (3)
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| US34737010P | 2010-05-21 | 2010-05-21 | |
| US347370P | 2010-05-21 | ||
| PCT/US2011/037412 WO2011146882A1 (en) | 2010-05-21 | 2011-05-20 | Chemical compounds, compositions and methods for kinase modulation |
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| ES2593256T3 true ES2593256T3 (es) | 2016-12-07 |
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| ES11784354.0T Active ES2593256T3 (es) | 2010-05-21 | 2011-05-20 | Compuestos químicos, composiciones y métodos para las modulaciones de cinasas |
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| US (3) | US8604032B2 (https=) |
| EP (1) | EP2571357B1 (https=) |
| JP (2) | JP5951600B2 (https=) |
| CN (1) | CN103002738A (https=) |
| AU (1) | AU2011255218B2 (https=) |
| CA (1) | CA2799579A1 (https=) |
| ES (1) | ES2593256T3 (https=) |
| WO (1) | WO2011146882A1 (https=) |
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| US8828998B2 (en) * | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| JP6207100B2 (ja) | 2012-12-21 | 2017-10-04 | ギリアード カリストガ エルエルシー | イソキノリノンまたはキナゾリノンホスファチジルイノシトール３−キナーゼ阻害剤 |
| US20160024051A1 (en) | 2013-03-15 | 2016-01-28 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| US9481667B2 (en) | 2013-03-15 | 2016-11-01 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| ES2667173T3 (es) | 2013-06-14 | 2018-05-09 | Gilead Calistoga Llc | Inhibidores de fosfatidilinositol 3-quinasa |
| UY35675A (es) | 2013-07-24 | 2015-02-27 | Novartis Ag | Derivados sustituidos de quinazolin-4-ona |
-
2011
- 2011-05-20 CA CA2799579A patent/CA2799579A1/en not_active Abandoned
- 2011-05-20 JP JP2013511397A patent/JP5951600B2/ja not_active Expired - Fee Related
- 2011-05-20 ES ES11784354.0T patent/ES2593256T3/es active Active
- 2011-05-20 US US13/112,611 patent/US8604032B2/en not_active Expired - Fee Related
- 2011-05-20 CN CN2011800356311A patent/CN103002738A/zh active Pending
- 2011-05-20 WO PCT/US2011/037412 patent/WO2011146882A1/en not_active Ceased
- 2011-05-20 AU AU2011255218A patent/AU2011255218B2/en not_active Ceased
- 2011-05-20 EP EP11784354.0A patent/EP2571357B1/en not_active Not-in-force
-
2013
- 2013-11-20 US US14/085,660 patent/US9181221B2/en active Active
-
2015
- 2015-09-29 US US14/869,637 patent/US9738644B2/en not_active Expired - Fee Related
-
2016
- 2016-04-07 JP JP2016076991A patent/JP2016172744A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2571357A1 (en) | 2013-03-27 |
| US9738644B2 (en) | 2017-08-22 |
| EP2571357B1 (en) | 2016-07-06 |
| US9181221B2 (en) | 2015-11-10 |
| AU2011255218A1 (en) | 2012-12-20 |
| US20140088099A1 (en) | 2014-03-27 |
| US8604032B2 (en) | 2013-12-10 |
| JP2016172744A (ja) | 2016-09-29 |
| WO2011146882A1 (en) | 2011-11-24 |
| EP2571357A4 (en) | 2013-11-20 |
| AU2011255218B2 (en) | 2015-03-12 |
| CN103002738A (zh) | 2013-03-27 |
| JP5951600B2 (ja) | 2016-07-13 |
| US20160016957A1 (en) | 2016-01-21 |
| US20120059000A1 (en) | 2012-03-08 |
| JP2013526586A (ja) | 2013-06-24 |
| CA2799579A1 (en) | 2011-11-24 |
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