EE04676B1 - Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine - Google Patents

Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Info

Publication number
EE04676B1
EE04676B1 EEP200000626A EEP200000626A EE04676B1 EE 04676 B1 EE04676 B1 EE 04676B1 EE P200000626 A EEP200000626 A EE P200000626A EE P200000626 A EEP200000626 A EE P200000626A EE 04676 B1 EE04676 B1 EE 04676B1
Authority
EE
Estonia
Prior art keywords
imidazopidine
derivatives
preparation
gastric acid
acid secretion
Prior art date
Application number
EEP200000626A
Other languages
English (en)
Estonian (et)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000626A publication Critical patent/EE200000626A/xx
Publication of EE04676B1 publication Critical patent/EE04676B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000626A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine EE04676B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000626A EE200000626A (et) 2002-04-15
EE04676B1 true EE04676B1 (et) 2006-08-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Country Status (34)

Country Link
US (2) US6313137B1 (sl)
EP (4) EP1491542B1 (sl)
JP (2) JP3883383B2 (sl)
KR (3) KR100650472B1 (sl)
CN (2) CN1165535C (sl)
AR (2) AR015769A1 (sl)
AT (4) ATE307130T1 (sl)
AU (2) AU769190B2 (sl)
BR (2) BR9909996B1 (sl)
CA (2) CA2329921A1 (sl)
CZ (2) CZ293977B6 (sl)
DE (4) DE69928792T2 (sl)
DK (2) DK1073657T3 (sl)
EE (2) EE04676B1 (sl)
ES (2) ES2252975T3 (sl)
HK (5) HK1033457A1 (sl)
HU (2) HUP0102313A3 (sl)
ID (2) ID26819A (sl)
IL (4) IL139200A0 (sl)
IS (2) IS5683A (sl)
MY (2) MY121379A (sl)
NO (2) NO317262B1 (sl)
NZ (2) NZ507638A (sl)
PL (2) PL195000B1 (sl)
RU (2) RU2235725C2 (sl)
SA (2) SA99200065B1 (sl)
SE (1) SE9801526D0 (sl)
SI (1) SI1073656T1 (sl)
SK (2) SK285768B6 (sl)
TR (4) TR200003176T2 (sl)
TW (2) TWI250159B (sl)
UA (2) UA66846C2 (sl)
WO (2) WO1999055706A1 (sl)
ZA (2) ZA200005796B (sl)

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US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
EP1368006B1 (en) * 2001-02-13 2006-05-03 AstraZeneca AB Novel modified released formulation
IL157461A0 (en) * 2001-03-08 2004-03-28 Astrazeneca Ab Astrazeneca Ab Use of carboxamido imidazo [1,2] pyridine deivatives in the preparation of medicaments for treating or preventing gastric ulcer
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
ATE378336T1 (de) 2002-09-19 2007-11-15 Schering Corp Imidazopyridine als hemmstoffe cyclin abhängiger kinasen
JP2006508142A (ja) 2002-11-19 2006-03-09 アルタナ　ファルマ　アクチエンゲゼルシャフト ８−置換イミダゾピリジン
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
NZ541861A (en) 2003-02-26 2009-05-31 Sugen Inc Aminoheteroaryl compounds as protein kinase inhibitors
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CN1874772A (zh) * 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
WO2005070927A2 (en) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
DE602005009257D1 (de) * 2004-12-17 2008-10-02 Pfizer Chroman-derivate als säurepumpenantagonisten
WO2006097456A1 (en) 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
MY147647A (en) * 2005-03-21 2012-12-31 S Bio Pte Ltd Imidazo [1,2-a] pyridine derivatives : preparation and pharmaceutical applications
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
WO2006100119A1 (en) * 2005-03-24 2006-09-28 Glaxo Group Limited Derivatives of imidazo (1,2-a) pyridine useful as medicaments for treating gastrointestinal diseases
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
WO2007066185A2 (en) 2005-12-05 2007-06-14 Pfizer Products Inc. Polymorphs of a c-met/hgfr inhibitor
SI1959955T1 (sl) 2005-12-05 2011-02-28 Pfizer Prod Inc Postopek zdravljenja abnormalne celične rasti
EP1996589A1 (en) * 2006-03-17 2008-12-03 RaQualia Pharma Inc Chromane derivatives
WO2008013785A2 (en) 2006-07-24 2008-01-31 Singh-Broemer And Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
GB2471619B (en) * 2008-03-31 2012-10-31 Council Scient Ind Res Method for the simultaneous preparation of 3-acetoxy-17-acetamdo-16-formyl-androst-5,16-diene and 3-acetoxy-2'-chloro-5-androsteno[17,6-B]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
KR101605063B1 (ko) * 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
CN105358151B (zh) * 2013-06-25 2019-04-12 豪夫迈·罗氏有限公司 用于治疗脊髓性肌萎缩的化合物
US9944637B2 (en) 2013-12-16 2018-04-17 Asana Biosciences, Llc P2X3 and/or P2X2/3 compounds and methods
WO2015148464A1 (en) * 2014-03-24 2015-10-01 Arqule Inc. Process of preparing 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3h-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
US11666888B2 (en) 2018-02-05 2023-06-06 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand
EP3774719A1 (de) 2018-04-10 2021-02-17 Bayer Aktiengesellschaft Verfahren zur herstellung von 2,6-dialkylphenyl-essigsäuren
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
ES2949232T3 (es) 2019-11-04 2023-09-26 Cinclus Pharma Holding Ab Publ Formulación Oral de X842
CA3235361A1 (en) 2021-11-05 2023-05-11 Kjell JARRING Polymorphs of the hydrochloride salt of linaprazan glurate
WO2023079093A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the mesylate salt of linaprazan glurate
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법

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Also Published As

Publication number Publication date
HK1036981A1 (en) 2002-01-25
IS5684A (is) 2000-10-25
JP3883383B2 (ja) 2007-02-21
SK285768B6 (sk) 2007-07-06
WO1999055706A9 (en) 2000-03-16
NO20005451D0 (no) 2000-10-27
SE9801526D0 (sv) 1998-04-29
HUP0102425A3 (en) 2002-12-28
EP1491543B1 (en) 2007-09-05
NZ507639A (en) 2004-01-30
MY121389A (en) 2006-01-28
NZ507638A (en) 2003-10-31
ES2252975T3 (es) 2006-05-16
IL139200A0 (en) 2001-11-25
SK14922000A3 (sk) 2001-06-11
KR100595806B1 (ko) 2006-07-03
HK1036984A1 (en) 2002-01-25
ID27530A (id) 2001-04-12
DE69928792D1 (de) 2006-01-12
EP1073656A1 (en) 2001-02-07
DE69937077D1 (de) 2007-10-18
EP1491542A3 (en) 2005-01-05
EP1073656B1 (en) 2005-10-19
NO20005451L (no) 2000-12-27
JP2002513025A (ja) 2002-05-08
BR9909995B1 (pt) 2010-07-13
RU2238271C2 (ru) 2004-10-20
EE04916B1 (et) 2007-10-15
BR9909995A (pt) 2000-12-26
HUP0102425A2 (hu) 2001-11-28
ATE372339T1 (de) 2007-09-15
TWI250159B (en) 2006-03-01
PL343801A1 (en) 2001-09-10
SA99200065B1 (ar) 2006-11-07
EP1073657B1 (en) 2005-12-07
EP1073657A1 (en) 2001-02-07
CZ293977B6 (cs) 2004-09-15
CZ20003982A3 (cs) 2001-02-14
SA99200064B1 (ar) 2006-10-11
DE69927803D1 (de) 2006-03-02
PL343797A1 (en) 2001-09-10
HUP0102313A2 (hu) 2001-12-28
CN1307577A (zh) 2001-08-08
HK1033317A1 (en) 2001-08-24
CA2329922C (en) 2006-04-11
CZ20003981A3 (cs) 2001-03-14
DE69937076T2 (de) 2008-05-29
CN1165535C (zh) 2004-09-08
UA66846C2 (uk) 2004-06-15
CA2329921A1 (en) 1999-11-04
DE69937077T2 (de) 2008-05-29
CZ292567B6 (cs) 2003-10-15
KR20050121760A (ko) 2005-12-27
HK1071139A1 (en) 2005-07-08
ES2249913T3 (es) 2006-04-01
KR100650472B1 (ko) 2006-11-28
AU769190B2 (en) 2004-01-22
DK1073656T3 (da) 2006-01-16
SA99200065A (ar) 2005-12-03
EP1491542A2 (en) 2004-12-29
PL195000B1 (pl) 2007-07-31
KR20010043133A (ko) 2001-05-25
JP3692034B2 (ja) 2005-09-07
ZA200005797B (en) 2002-01-18
AR015768A1 (es) 2001-05-16
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
BR9909996A (pt) 2000-12-26
ATE372340T1 (de) 2007-09-15
RU2235725C2 (ru) 2004-09-10
DK1073657T3 (da) 2006-03-13
HK1033457A1 (en) 2001-08-31
DE69928792T2 (de) 2006-07-20
MY121379A (en) 2006-01-28
CN1306533A (zh) 2001-08-01
US6313136B1 (en) 2001-11-06
AR015769A1 (es) 2001-05-16
EE200000626A (et) 2002-04-15
HUP0102313A3 (en) 2002-10-28
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
UA67769C2 (uk) 2004-07-15
ATE312101T1 (de) 2005-12-15
AU4300799A (en) 1999-11-16
IL139297A0 (en) 2001-11-25
IL139297A (en) 2007-06-03
JP2002513024A (ja) 2002-05-08
SK14912000A3 (sk) 2001-06-11
TR200102612T2 (tr) 2002-06-21
TR200003149T2 (tr) 2001-03-21
ID26819A (id) 2001-02-15
IS5683A (is) 2000-10-25
ZA200005796B (en) 2002-01-18
AU769108B2 (en) 2004-01-15
TR200102728T2 (tr) 2002-06-21
KR100595805B1 (ko) 2006-07-03
WO1999055705A1 (en) 1999-11-04
US6313137B1 (en) 2001-11-06
ATE307130T1 (de) 2005-11-15
TR200003176T2 (tr) 2001-03-21
CN1174980C (zh) 2004-11-10
NO20005450L (no) 2000-12-22
TW490466B (en) 2002-06-11
NO20005450D0 (no) 2000-10-27
BR9909996B1 (pt) 2010-08-24
DE69937076D1 (de) 2007-10-18
DE69927803T2 (de) 2006-07-06
CA2329922A1 (en) 1999-11-04
NO317262B1 (no) 2004-09-27
EP1491543A1 (en) 2004-12-29
IL139200A (en) 2010-04-29
AU4300699A (en) 1999-11-16
KR20010043134A (ko) 2001-05-25
NO318203B1 (no) 2005-02-14

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