EA039219B1 - Антитела к tigit - Google Patents

Антитела к tigit Download PDF

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Publication number
EA039219B1
EA039219B1 EA201791171A EA201791171A EA039219B1 EA 039219 B1 EA039219 B1 EA 039219B1 EA 201791171 A EA201791171 A EA 201791171A EA 201791171 A EA201791171 A EA 201791171A EA 039219 B1 EA039219 B1 EA 039219B1
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EA
Eurasian Patent Office
Prior art keywords
antibody
antibodies
tigit
human
binding
Prior art date
Application number
EA201791171A
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English (en)
Russian (ru)
Other versions
EA201791171A1 (ru
Inventor
Марк Ф. Морер
Цен-Хуи Тимоти Чен
Брижитт Дево
Мохан Сринивасан
Сьюзан Х. Джульен
Пол О. Шеппард
Дэниэл Ф. Ардурел
Индрани Чакраборти
Original Assignee
Бристол-Майерс Сквибб Компани
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Application filed by Бристол-Майерс Сквибб Компани filed Critical Бристол-Майерс Сквибб Компани
Publication of EA201791171A1 publication Critical patent/EA201791171A1/ru
Publication of EA039219B1 publication Critical patent/EA039219B1/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EA201791171A 2014-12-23 2015-12-22 Антитела к tigit EA039219B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462096267P 2014-12-23 2014-12-23
PCT/US2015/067332 WO2016106302A1 (en) 2014-12-23 2015-12-22 Antibodies to tigit

Publications (2)

Publication Number Publication Date
EA201791171A1 EA201791171A1 (ru) 2017-11-30
EA039219B1 true EA039219B1 (ru) 2021-12-20

Family

ID=55168435

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201791171A EA039219B1 (ru) 2014-12-23 2015-12-22 Антитела к tigit

Country Status (23)

Country Link
US (3) US10189902B2 (OSRAM)
EP (2) EP3237448A1 (OSRAM)
JP (6) JP6180663B2 (OSRAM)
KR (1) KR102644115B1 (OSRAM)
CN (3) CN116731176A (OSRAM)
AR (1) AR103268A1 (OSRAM)
AU (2) AU2015369683C1 (OSRAM)
BR (1) BR112017013385A2 (OSRAM)
CL (1) CL2017001660A1 (OSRAM)
CO (1) CO2017006989A2 (OSRAM)
EA (1) EA039219B1 (OSRAM)
IL (2) IL253013B (OSRAM)
MA (1) MA40662B1 (OSRAM)
MX (2) MX389267B (OSRAM)
MY (1) MY187045A (OSRAM)
PE (1) PE20171244A1 (OSRAM)
PH (2) PH12022550771A1 (OSRAM)
SG (2) SG10202006538TA (OSRAM)
TN (1) TN2017000267A1 (OSRAM)
TW (1) TWI708786B (OSRAM)
UY (1) UY36471A (OSRAM)
WO (1) WO2016106302A1 (OSRAM)
ZA (2) ZA201704981B (OSRAM)

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