MX2019014265A - Tratamientos conjuntos triples con anticuerpos. - Google Patents
Tratamientos conjuntos triples con anticuerpos.Info
- Publication number
- MX2019014265A MX2019014265A MX2019014265A MX2019014265A MX2019014265A MX 2019014265 A MX2019014265 A MX 2019014265A MX 2019014265 A MX2019014265 A MX 2019014265A MX 2019014265 A MX2019014265 A MX 2019014265A MX 2019014265 A MX2019014265 A MX 2019014265A
- Authority
- MX
- Mexico
- Prior art keywords
- triple combination
- antibody therapies
- combination antibody
- antibodies
- therapies
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
Abstract
La presente invención se refiere a tratamientos conjuntos triples con anticuerpos anti-TIGIT, anticuerpos anti-PVRIG e inhibidores de punto de control, que incluyen anti-PD-1 o anti-PD-L1.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762513960P | 2017-06-01 | 2017-06-01 | |
US201762515452P | 2017-06-05 | 2017-06-05 | |
US201762538563P | 2017-07-28 | 2017-07-28 | |
US201762547051P | 2017-08-17 | 2017-08-17 | |
US201762582756P | 2017-11-07 | 2017-11-07 | |
US201862618005P | 2018-01-16 | 2018-01-16 | |
PCT/IB2018/000696 WO2018220446A1 (en) | 2017-06-01 | 2018-06-01 | Triple combination antibody therapies |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019014265A true MX2019014265A (es) | 2020-08-03 |
Family
ID=63080202
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019014265A MX2019014265A (es) | 2017-06-01 | 2018-06-01 | Tratamientos conjuntos triples con anticuerpos. |
MX2024005976A MX2024005976A (es) | 2017-06-01 | 2019-11-28 | Un anticuerpo anti-tigit, un anticuerpo anti-pvrig y un anticuerpo anti-pd-1 para usarse en el tratamiento de cancer. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2024005976A MX2024005976A (es) | 2017-06-01 | 2019-11-28 | Un anticuerpo anti-tigit, un anticuerpo anti-pvrig y un anticuerpo anti-pd-1 para usarse en el tratamiento de cancer. |
Country Status (13)
Country | Link |
---|---|
US (2) | US11225523B2 (es) |
EP (1) | EP3630180A1 (es) |
JP (2) | JP7348072B2 (es) |
KR (1) | KR20200021474A (es) |
CN (1) | CN110799213A (es) |
AU (1) | AU2018276140A1 (es) |
BR (1) | BR112019025035A2 (es) |
CA (1) | CA3064331A1 (es) |
CL (1) | CL2019003509A1 (es) |
IL (1) | IL271011A (es) |
MX (2) | MX2019014265A (es) |
SG (1) | SG10202111336RA (es) |
WO (1) | WO2018220446A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
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DK3347379T5 (da) * | 2016-08-17 | 2020-06-15 | Compugen Ltd | Anti-tigit-antistoffer, anti-pvrig-antistoffer og kombinationer deraf |
EP3548071A4 (en) * | 2016-11-30 | 2020-07-15 | OncoMed Pharmaceuticals, Inc. | METHOD FOR TREATING CANCER WITH TIGIT-BINDING ACTIVE SUBSTANCES |
MA52459A (fr) | 2017-06-05 | 2021-03-10 | Janssen Biotech Inc | Anticorps se liant spécifiquement à pd-1 et leurs méthodes d'utilisation |
CN109970856B (zh) | 2017-12-27 | 2022-08-23 | 信达生物制药(苏州)有限公司 | 抗lag-3抗体及其用途 |
US20190382477A1 (en) * | 2018-06-01 | 2019-12-19 | Compugen Ltd. | Anti-pvrig/anti-tigit bispecific antibodies and methods of use |
TWI756621B (zh) * | 2019-01-25 | 2022-03-01 | 大陸商信達生物製藥(蘇州)有限公司 | 新型雙特異性抗體分子以及同時結合pd-l1和lag-3的雙特異性抗體 |
CN114025757A (zh) * | 2019-04-18 | 2022-02-08 | Qlsf生物治疗药物公司 | 人源化抗pd-l1抗体 |
JP2022537053A (ja) * | 2019-06-21 | 2022-08-23 | シングル セル テクノロジー, インコーポレイテッド | 抗tigit抗体 |
CN114746116A (zh) * | 2019-11-15 | 2022-07-12 | 表面免疫肿瘤学公司 | 用于免疫疗法的组合物和方法 |
WO2021180205A1 (zh) * | 2020-03-13 | 2021-09-16 | 江苏恒瑞医药股份有限公司 | Pvrig结合蛋白及其医药用途 |
CN113563470B (zh) * | 2020-04-29 | 2023-02-10 | 广州昂科免疫生物技术有限公司 | 结合tigit抗原的抗体及其制备方法与应用 |
CN111995681B (zh) * | 2020-05-09 | 2022-03-08 | 华博生物医药技术(上海)有限公司 | 抗tigit的抗体、其制备方法和应用 |
MX2022014734A (es) * | 2020-05-26 | 2023-03-15 | Regeneron Pharma | Metodos de tratamiento del cancer de cuello uterino mediante la administracion del anticuerpo inhibidor de pd-1 cemiplimab. |
TW202200616A (zh) | 2020-06-18 | 2022-01-01 | 美商建南德克公司 | 使用抗tigit抗體及pd-1軸結合拮抗劑之治療 |
WO2021263115A1 (en) * | 2020-06-26 | 2021-12-30 | Icahn School Of Medicine At Mount Sinai | Compositions and methods for treating cancer, overcoming pd-1/pd-l1 blockade resistance, and determining resistance to checkpoint inhibitor treatment |
TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Tigit及cd112r阻斷 |
WO2022069940A1 (en) * | 2020-09-30 | 2022-04-07 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies |
WO2022165275A2 (en) * | 2021-01-28 | 2022-08-04 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations and anti-pd-1-antibodies |
EP4284516A1 (en) * | 2021-01-28 | 2023-12-06 | Compugen Ltd. | Anti-pvrig antibodies formulations and uses thereof |
JP2024527049A (ja) | 2021-07-28 | 2024-07-19 | ジェネンテック, インコーポレイテッド | がんを治療するための方法及び組成物 |
CA3231320A1 (en) | 2021-09-15 | 2023-03-23 | Zhiliang CAO | Protein specifically binding to pd-1 and pharmaceutical use thereof |
TW202321308A (zh) | 2021-09-30 | 2023-06-01 | 美商建南德克公司 | 使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法 |
WO2023063842A1 (ru) * | 2021-10-12 | 2023-04-20 | Общество с ограниченной ответственностью "Пальмира Биофарма" | Нуклеотидная последовательность, кодирующая слитый белок |
WO2023064958A1 (en) * | 2021-10-15 | 2023-04-20 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies |
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-
2018
- 2018-06-01 EP EP18749490.1A patent/EP3630180A1/en active Pending
- 2018-06-01 CN CN201880043405.XA patent/CN110799213A/zh active Pending
- 2018-06-01 KR KR1020197037964A patent/KR20200021474A/ko active Search and Examination
- 2018-06-01 BR BR112019025035-2A patent/BR112019025035A2/pt unknown
- 2018-06-01 WO PCT/IB2018/000696 patent/WO2018220446A1/en active Application Filing
- 2018-06-01 CA CA3064331A patent/CA3064331A1/en active Pending
- 2018-06-01 AU AU2018276140A patent/AU2018276140A1/en active Pending
- 2018-06-01 US US15/996,369 patent/US11225523B2/en active Active
- 2018-06-01 SG SG10202111336RA patent/SG10202111336RA/en unknown
- 2018-06-01 JP JP2019565817A patent/JP7348072B2/ja active Active
- 2018-06-01 MX MX2019014265A patent/MX2019014265A/es unknown
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2019
- 2019-11-28 MX MX2024005976A patent/MX2024005976A/es unknown
- 2019-11-28 IL IL271011A patent/IL271011A/en unknown
- 2019-11-29 CL CL2019003509A patent/CL2019003509A1/es unknown
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2021
- 2021-12-07 US US17/544,852 patent/US20230070685A1/en active Pending
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2023
- 2023-05-31 JP JP2023090131A patent/JP2023123462A/ja active Pending
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BR112019025035A2 (pt) | 2020-06-30 |
US20190010246A1 (en) | 2019-01-10 |
WO2018220446A9 (en) | 2019-08-22 |
CL2019003509A1 (es) | 2020-10-02 |
WO2018220446A1 (en) | 2018-12-06 |
IL271011A (en) | 2020-01-30 |
JP7348072B2 (ja) | 2023-09-20 |
JP2020521778A (ja) | 2020-07-27 |
US11225523B2 (en) | 2022-01-18 |
AU2018276140A1 (en) | 2019-12-19 |
JP2023123462A (ja) | 2023-09-05 |
CN110799213A (zh) | 2020-02-14 |
US20230070685A1 (en) | 2023-03-09 |
KR20200021474A (ko) | 2020-02-28 |
MX2024005976A (es) | 2024-06-11 |
SG10202111336RA (en) | 2021-11-29 |
EP3630180A1 (en) | 2020-04-08 |
CA3064331A1 (en) | 2018-12-06 |
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