MX2016011809A - Inmunoensayo de canalización de oxígeno luminiscente utilizando tres anticuerpos y metodos de produccion y uso de los mismos. - Google Patents

Inmunoensayo de canalización de oxígeno luminiscente utilizando tres anticuerpos y metodos de produccion y uso de los mismos.

Info

Publication number
MX2016011809A
MX2016011809A MX2016011809A MX2016011809A MX2016011809A MX 2016011809 A MX2016011809 A MX 2016011809A MX 2016011809 A MX2016011809 A MX 2016011809A MX 2016011809 A MX2016011809 A MX 2016011809A MX 2016011809 A MX2016011809 A MX 2016011809A
Authority
MX
Mexico
Prior art keywords
antibodies
methods
production
immunoassay utilizing
luminescent oxygen
Prior art date
Application number
MX2016011809A
Other languages
English (en)
Inventor
J Li Jay
J Ledden David
Scott Cowden Eric
Lu Donglai
Original Assignee
Siemens Healthcare Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Inc filed Critical Siemens Healthcare Diagnostics Inc
Publication of MX2016011809A publication Critical patent/MX2016011809A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure

Abstract

Se describen un sistema de detección quimioluminiscente, así como kits y dispositivos microfluídicos que contienen los mismos. También se describen métodos de uso de los sistemas, kits, y dispositivos. El primero, segundo, y tercer anticuerpos o fragmento de enlace de los mismos pueden proporcionarse en cualquier forma que permita que estos anticuerpos/fragmentos de enlace funcionen de acuerdo con los conceptos inventivos actualmente descritos y reivindicados. Por ejemplo, cada uno del primero, segundo, y tercer anticuerpos/fragmentos de enlace pueden ser un anticuerpo/fragmento de enlace policlonal o un anticuerpo/fragmento de enlace monoclonal.
MX2016011809A 2014-03-26 2015-03-24 Inmunoensayo de canalización de oxígeno luminiscente utilizando tres anticuerpos y metodos de produccion y uso de los mismos. MX2016011809A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461970596P 2014-03-26 2014-03-26
PCT/US2015/022209 WO2015148479A1 (en) 2014-03-26 2015-03-24 Luminescent oxygen channeling immunoassay utilizing three antibodies and methods of production and use thereof

Publications (1)

Publication Number Publication Date
MX2016011809A true MX2016011809A (es) 2017-05-10

Family

ID=54196294

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016011809A MX2016011809A (es) 2014-03-26 2015-03-24 Inmunoensayo de canalización de oxígeno luminiscente utilizando tres anticuerpos y metodos de produccion y uso de los mismos.

Country Status (11)

Country Link
US (2) US20170176419A1 (es)
EP (2) EP3483593B1 (es)
JP (1) JP6596440B2 (es)
CN (1) CN106662532B (es)
AU (1) AU2015236288A1 (es)
CA (1) CA2942281C (es)
DK (2) DK3483593T3 (es)
ES (2) ES2713428T3 (es)
IL (1) IL247630A0 (es)
MX (1) MX2016011809A (es)
WO (1) WO2015148479A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10871488B2 (en) 2016-12-09 2020-12-22 Abbott Point Of Care Inc. Crossover analytical systems and methods using an immunosensor and magnetic immunosensor
WO2018107013A1 (en) * 2016-12-09 2018-06-14 Abbott Point Of Care Inc. Dual range cardiac troponin immunoassay devices and methods using immunosensor and magnetic immunosensor
ES2869625T3 (es) 2016-12-09 2021-10-25 Abbott Point Of Care Inc Sistemas y dispositivos de inmunoensayo combinado e inmunoensayo magnético para un intervalo extendido de sensibilidad
US10935511B2 (en) 2016-12-09 2021-03-02 Abbott Point Of Care Inc. Ameliorated crosstalk immunoassay test device for determining a concentration of an analyte
CN110214274B (zh) 2016-12-09 2023-07-25 雅培医护站股份有限公司 使用免疫传感器和磁免疫传感器的扩展范围的免疫测定装置
CN110178032B (zh) 2016-12-09 2023-08-11 雅培医护站股份有限公司 用于扩展范围的灵敏度的联合免疫测定和磁免疫测定方法
EP3760640A4 (en) * 2018-02-27 2021-11-17 Shimadzu Corporation ANTIBODIES SPECIFICALLY RECOGNIZING THE N-TERMINAL END OF APP669-X, AND METHOD OF IMMUNOLOGICAL ASSAY
WO2019167128A1 (ja) * 2018-02-27 2019-09-06 株式会社 島津製作所 サンドイッチ型免疫測定法
JP7122454B2 (ja) * 2018-07-30 2022-08-19 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド ビオチンアッセイを実施するためのキット、マイクロ流体デバイス、および方法
US11287429B2 (en) 2018-09-25 2022-03-29 Siemens Healthcare Diagnostics Inc. Compositions, kits, and methods for multiplex assays to correct for biotin interference in target analyte measurements
MX2022002252A (es) * 2019-08-29 2022-03-22 Siemens Healthcare Diagnostics Inc Dispositivo y metodo para evaluar una muestra de fluido en un producto consumible de multiples analitos de un solo uso.
CN111781385B (zh) * 2020-08-19 2023-07-18 武汉生之源生物科技股份有限公司 一种NT-proBNP检测试剂盒及其制备方法
CN114544978A (zh) * 2022-03-04 2022-05-27 美康生物科技股份有限公司 一种igf-1检测试剂盒及其制备方法和检测方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
NO164622C (no) * 1988-05-11 1990-10-24 Tore Lindmo Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav.
EP0542810A1 (en) 1990-08-02 1993-05-26 B.R. Centre Limited Methods for the production of proteins with a desired function
US6251581B1 (en) * 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5340716A (en) 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
EP0515194B1 (en) * 1991-05-22 2001-10-31 Dade Behring Marburg GmbH Assay methods utilizing induced luminescence
US7285418B2 (en) * 1996-06-25 2007-10-23 Hytest Ltd. Method and kit for the diagnosis of troponin I
US6248546B1 (en) * 1998-03-09 2001-06-19 Diagnostic Systems Laboratories, Inc. Assay of IGFBP complex
US6703248B1 (en) * 1999-12-15 2004-03-09 Dade Behring Marburg Gmbh Particles for diagnostic and therapeutic use
DE10064827A1 (de) * 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
US6551788B1 (en) * 2001-11-28 2003-04-22 Beckman Coulter, Inc. Particle-based ligand assay with extended dynamic range
US6764819B2 (en) * 2002-07-16 2004-07-20 Emp Biotech Gmbh Method for chemiluminescent detection
DE112004001863T5 (de) * 2003-10-03 2006-09-07 Scantibodies Laboratory, Inc., Santee Verfahren und Verwendung von Bindungskomponenten zur Verbesserung der Testspezifität
EP1794282A4 (en) * 2004-09-20 2011-03-23 Boston Microfluidics MICROFLUIDIC DEVICE FOR DETECTION OF SOLUBLE MOLECULES
WO2006119203A2 (en) * 2005-04-29 2006-11-09 Beckman Coulter Fluorescence lateral flow immunoassay
GB2436616A (en) * 2006-03-29 2007-10-03 Inverness Medical Switzerland Assay device and method
MX2009003048A (es) * 2006-09-21 2009-09-07 Prometheus Lab Inc Disposiciones a base de anticuerpo para detectar transductores de multiple señal en celulas circulantes raras.
CN104151430A (zh) * 2007-03-01 2014-11-19 西福根有限公司 重组抗表皮生长因子受体抗体组合物
US7790401B2 (en) * 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
US20090170218A1 (en) * 2008-01-02 2009-07-02 Dade Behring Inc. Methods for detection of cyclosporin a
WO2011087813A2 (en) * 2009-12-22 2011-07-21 University Of Washington Capillarity-based devices for performing chemical processes and associated systems and methods
US9678068B2 (en) * 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US10088490B2 (en) * 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
CN102565381B (zh) * 2010-12-08 2014-06-18 中国科学院生态环境研究中心 导电微粒子介导电化学发光信号的免疫检测方法
JP6226872B2 (ja) 2011-11-22 2017-11-08 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． キャリブレーションおよび／またはクオリティ・コントロール溶液として再構成用の乾燥試薬を含むデバイスとその製造および使用方法
WO2014152165A1 (en) * 2013-03-15 2014-09-25 Siemens Healthcare Diagnostics Inc. Luminescent oxygen channeling immunoassays utilizing electrochemical discharge of singlet oxygen and methods of production and use thereof
US20160320415A1 (en) * 2013-12-16 2016-11-03 Xen Biofluidx, Inc. Fast reconstituting reagent pellets

Also Published As

Publication number Publication date
EP3123151B1 (en) 2018-11-28
CA2942281C (en) 2023-03-14
ES2884930T3 (es) 2021-12-13
US20210231647A1 (en) 2021-07-29
CA2942281A1 (en) 2015-10-01
EP3123151A1 (en) 2017-02-01
EP3483593B1 (en) 2021-04-28
ES2713428T3 (es) 2019-05-21
CN106662532B (zh) 2019-12-13
IL247630A0 (en) 2016-11-30
JP6596440B2 (ja) 2019-10-23
DK3483593T3 (da) 2021-07-19
US20170176419A1 (en) 2017-06-22
EP3483593A1 (en) 2019-05-15
EP3123151A4 (en) 2017-03-22
CN106662532A (zh) 2017-05-10
DK3123151T3 (en) 2019-03-18
AU2015236288A1 (en) 2016-09-15
WO2015148479A1 (en) 2015-10-01
JP2017508971A (ja) 2017-03-30

Similar Documents

Publication Publication Date Title
MX2016011809A (es) Inmunoensayo de canalización de oxígeno luminiscente utilizando tres anticuerpos y metodos de produccion y uso de los mismos.
MX2020010382A (es) Anticuerpos biespecificos para pd1 y tim3.
PH12018502225A1 (en) Anti-il-33 antibodies, compositions, methods and uses thereof
MX2020009649A (es) Anticuerpos monoclonales contra bcma.
PH12018501042A1 (en) Antibodies and antibody fragments for site-specific conjugation
PH12018500295A1 (en) Chimeric antigen receptors based on single-domain antibodies and methods of use thereof
PH12017502019A1 (en) Heterodimeric antibodies that bind cd3 and tumor antigens
EP4257613A3 (en) Bispecific checkpoint inhibitor antibodies
NZ628314A (en) Cd47 antibodies and methods of use thereof
EA201791139A1 (ru) Гетеродимерные антитела, которые связывают cd3 и опухолевые антигены
PH12017502180A1 (en) Tau-binding antibodies
EA201891709A1 (ru) Антигенсвязывающие белки, связывающие pd-l1
EP3954713A3 (en) Bispecific antibodies that bind to cd38 and cd3
AU2016219350A8 (en) Humanized anti-MUC1* antibodies
EA201591806A1 (ru) Лечение и профилактика острой почечной недостаточности с применением анти-альфа-v-бета-5 антител
PH12019502087A1 (en) Anti-par2 antibodies and uses thereof
NZ631098A (en) Anti-hepcidin antibodies and uses thereof
PH12017502207A1 (en) Tau-binding antibodies
MX2016008196A (es) Anticuerpos y metodos de uso.
EA201990673A1 (ru) Антитела, специфически связывающиеся с il-17a, и их функциональные фрагменты
WO2018119425A3 (en) Anti-lilrb3 antibodies and methods of use thereof
NZ629553A (en) Anti-big-endothelin-1 (big-et-1) antibodies and uses thereof
MX2020003193A (es) Anticuerpos recombinantes mono- o biespecificos multivalentes para fines analiticos.
EP4079760A3 (en) Antibodies against clostridium difficile toxins and methods of using the same
SA518391028B1 (ar) Cd37 أجسام مضادة واختبارات للكشف عن

Legal Events

Date Code Title Description
FG Grant or registration