US4816570A
(en)
|
1982-11-30 |
1989-03-28 |
The Board Of Regents Of The University Of Texas System |
Biologically reversible phosphate and phosphonate protective groups
|
US4968788A
(en)
|
1986-04-04 |
1990-11-06 |
Board Of Regents, The University Of Texas System |
Biologically reversible phosphate and phosphonate protective gruops
|
EP0533833B1
(en)
|
1990-06-13 |
1995-12-20 |
GLAZIER, Arnold |
Phosphorous produgs
|
ES2118069T3
(es)
|
1990-09-14 |
1998-09-16 |
Acad Of Science Czech Republic |
Profarmacos de fosfonatos.
|
US6887707B2
(en)
|
1996-10-28 |
2005-05-03 |
University Of Washington |
Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA
|
ATE254632T1
(de)
|
1998-03-03 |
2003-12-15 |
Novo Nordisk As |
Neue salzformn von (2e)-5-amino-5-methylhex-2- enolsäure n-methyl-n-((1r)-1-(methylcarbamoyl)-2- phruylrthyl) carbamoyl)-2-(2-naphtyl)ethyl)amid
|
US6312662B1
(en)
|
1998-03-06 |
2001-11-06 |
Metabasis Therapeutics, Inc. |
Prodrugs phosphorus-containing compounds
|
CA2326535A1
(en)
|
1998-03-27 |
1999-10-07 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
WO2000023449A1
(en)
|
1998-10-16 |
2000-04-27 |
Merck Sharp & Dohme Limited |
Pyrazolo-triazine derivatives as ligands for gaba receptors
|
DE19912636A1
(de)
|
1999-03-20 |
2000-09-21 |
Aventis Cropscience Gmbh |
Bicyclische Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und pharmazeutische Mittel
|
JP2003514766A
(ja)
|
1999-06-03 |
2003-04-22 |
アボット・ラボラトリーズ |
活性剤としてルイス酸を用いるオリゴヌクレオチド合成
|
AUPQ105499A0
(en)
|
1999-06-18 |
1999-07-08 |
Biota Scientific Management Pty Ltd |
Antiviral agents
|
AU7490600A
(en)
|
1999-09-15 |
2001-04-17 |
Biocryst Pharmaceuticals, Inc. |
Inhibiting t-cell proliferation
|
US6566365B1
(en)
|
1999-11-04 |
2003-05-20 |
Biochem Pharma Inc. |
Method for the treatment of Flaviviridea viral infection using nucleoside analogues
|
CA2400274A1
(en)
|
2000-02-18 |
2001-08-23 |
Shire Biochem Inc. |
Method for the treatment or prevention of flavivirus infections using nucleoside analogues
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
EA007867B1
(ru)
|
2000-05-26 |
2007-02-27 |
Айденикс (Кайман) Лимитед |
Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения
|
EP1292313B1
(en)
|
2000-05-26 |
2004-09-08 |
Idenix (Cayman) Limited |
Methods for treating hepatitis delta virus infection with beta-l-2' deoxy-nucleosides
|
CN100402539C
(zh)
|
2000-07-21 |
2008-07-16 |
吉里德科学公司 |
核苷酸膦酸酯类似物前药及其筛选和制备方法
|
US20030008841A1
(en)
|
2000-08-30 |
2003-01-09 |
Rene Devos |
Anti-HCV nucleoside derivatives
|
DK1411954T3
(da)
|
2000-10-18 |
2011-03-14 |
Pharmasset Inc |
Modificerede nukleosider til behandling af virusinfektioner og abnorm cellulær proliferation
|
AUPR213700A0
(en)
|
2000-12-18 |
2001-01-25 |
Biota Scientific Management Pty Ltd |
Antiviral agents
|
CA2434386C
(en)
|
2001-01-22 |
2006-12-05 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
DE10145223A1
(de)
|
2001-09-13 |
2003-04-03 |
Basf Ag |
Verfahren zur Herstellung von meso-Zeaxanthin
|
EP1438054A4
(en)
|
2001-09-28 |
2006-07-26 |
Idenix Cayman Ltd |
METHODS AND COMPOSITIONS FOR TREATING FLAVIVIRUS AND PESTIVIRUS USING MODIFIED NUCLEOSIDE AT 4 'POSITION
|
AT410792B
(de)
|
2001-12-28 |
2003-07-25 |
Dsm Fine Chem Austria Gmbh |
Verfahren zur herstellung von geschützten, enantiomeren-angereicherten cyanhydrinen durch in-situ-derivatisierung
|
CA2477741A1
(en)
|
2002-02-28 |
2003-09-04 |
Biota, Inc. |
Nucleotide mimics and their prodrugs
|
CA2477795A1
(en)
|
2002-02-28 |
2003-09-12 |
Kandasamy Sakthivel |
Nucleoside 5'-monophosphate mimics and their prodrugs
|
US20040138170A1
(en)
|
2002-03-06 |
2004-07-15 |
Montgomery John A. |
Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
GB0210127D0
(en)
|
2002-05-02 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB0210124D0
(en)
|
2002-05-02 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
KR20050006221A
(ko)
|
2002-05-06 |
2005-01-15 |
제네랩스 테크놀로지스, 인코포레이티드 |
C형 간염 바이러스 감염 치료용의 뉴클레오시드 유도체
|
WO2003100009A2
(en)
|
2002-05-23 |
2003-12-04 |
Biocryst Pharmaceuticals, Inc. |
Enhancing the efficacy of reverse transcriptase and dna polymerase inhibitors (nucleoside analogs) using pnp inhibitors and/or 2'-deoxyguanosine and/or prodrug thereof
|
US7824851B2
(en)
|
2002-11-15 |
2010-11-02 |
Idenix Pharmaceuticals, Inc. |
2′-branched nucleosides and Flaviviridae mutation
|
TWI332507B
(en)
|
2002-11-19 |
2010-11-01 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
EP1628685B1
(en)
|
2003-04-25 |
2010-12-08 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
EP1646371A4
(en)
|
2003-06-26 |
2010-09-22 |
Biotron Ltd |
ANTIVIRAL COMPOSITIONS AND METHODS
|
GB0317009D0
(en)
|
2003-07-21 |
2003-08-27 |
Univ Cardiff |
Chemical compounds
|
JP2007501185A
(ja)
|
2003-07-25 |
2007-01-25 |
イデニクス(ケイマン)リミテツド |
C型肝炎を含むフラビウイルス関連疾患を治療するためのプリンヌクレオシド類似体
|
JP2007504152A
(ja)
|
2003-08-27 |
2007-03-01 |
ビオタ, インコーポレイテッド |
治療剤としての新規三環ヌクレオシドまたはヌクレオチド
|
JP2005187428A
(ja)
|
2003-12-26 |
2005-07-14 |
Univ Of Tokyo |
抗mgl抗体によるフィロウイルス治療薬
|
JP2005185235A
(ja)
|
2003-12-26 |
2005-07-14 |
Univ Of Tokyo |
ウイルス感染に対する感受性診断のための方法およびキット。
|
EP2360164A3
(de)
|
2004-03-16 |
2012-01-04 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituierte Benzol-Derivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
EP1758453B1
(en)
|
2004-06-15 |
2014-07-16 |
Merck Sharp & Dohme Corp. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
US7560434B2
(en)
|
2004-06-22 |
2009-07-14 |
Biocryst Pharmaceuticals, Inc. |
AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
EP1809301B1
(en)
|
2004-09-14 |
2019-11-06 |
Gilead Pharmasset LLC |
2-fluoro-2-alkyl-substituted d-ribonolactone intermediates
|
JP2008517912A
(ja)
|
2004-10-21 |
2008-05-29 |
メルク エンド カムパニー インコーポレーテッド |
RNA依存性RNAウイルス感染治療用フッ素化ピロロ[2,3−d]ピリミジンヌクレオシド
|
CA2585079A1
(en)
|
2004-10-29 |
2006-05-11 |
Biocryst Pharmaceuticals, Inc. |
Therapeutic furopyrimidines and thienopyrimidines
|
CA2587639A1
(en)
|
2004-12-16 |
2006-06-22 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
JP2008532950A
(ja)
|
2005-03-08 |
2008-08-21 |
バイオタ サイエンティフィック マネージメント ピーティーワイ リミテッド |
治療薬としての二環式ヌクレオシドおよび二環式ヌクレオチド
|
AU2006230023A1
(en)
|
2005-03-29 |
2006-10-05 |
Biocryst Pharmaceuticals, Inc. |
Hepatitis C therapies
|
TW200720285A
(en)
|
2005-04-25 |
2007-06-01 |
Genelabs Tech Inc |
Nucleoside compounds for treating viral infections
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
WO2007027248A2
(en)
|
2005-05-16 |
2007-03-08 |
Valeant Research & Development |
3', 5' - cyclic nucleoside analogues for treatment of hcv
|
PL2826770T3
(pl)
|
2005-06-24 |
2019-02-28 |
Biotron Limited |
Przeciwwirusowe związki acyloguanidynowe
|
CA2665370A1
(en)
|
2005-10-03 |
2007-04-12 |
University Health Network |
Odcase inhibitors for the treatment of malaria
|
EP1945222B1
(en)
|
2005-11-02 |
2012-12-26 |
Bayer Pharma Aktiengesellschaft |
Pyrrolo[2,1-f] [1,2,4]-triazin-4-ylamines as igf-1r kinase inhibitors for the treatment of cancer and other hyperproliferative diseases
|
NO20055456L
(no)
|
2005-11-17 |
2007-05-18 |
Fluens Synthesis As |
Kontinuerlig stromningsreaktor
|
JP5329969B2
(ja)
|
2005-12-01 |
2013-10-30 |
バジリア ファルマスーチカ アーゲー |
エポキシブタノール中間体の製造方法
|
PE20070855A1
(es)
|
2005-12-02 |
2007-10-14 |
Bayer Pharmaceuticals Corp |
Derivados de 4-amino-pirrolotriazina sustituida como inhibidores de quinasas
|
KR20130141706A
(ko)
|
2005-12-02 |
2013-12-26 |
바이엘 헬스케어 엘엘씨 |
과다-증식성 장애 및 맥관형성과 관련된 질환의 치료에 유용한 치환된 4-아미노-피롤로트리아진 유도체
|
JP5112328B2
(ja)
|
2005-12-09 |
2013-01-09 |
バジリア ファルマスーチカ アーゲー |
重度の皮膚科障害の局所的処置のための4−オキソ(イソ)トレチノイン
|
WO2007065829A1
(en)
|
2005-12-09 |
2007-06-14 |
F. Hoffmann-La Roche Ag |
Antiviral nucleosides
|
US7879815B2
(en)
*
|
2006-02-14 |
2011-02-01 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
WO2007097991A2
(en)
|
2006-02-16 |
2007-08-30 |
Pharmasset, Inc. |
Methods and kits for dosing of antiviral agents
|
DE102006015378A1
(de)
|
2006-04-03 |
2007-10-04 |
Ludwig-Maximilians-Universität München |
Verfahren zur Synthese von Organoelementverbindungen
|
CL2007001427A1
(es)
|
2006-05-22 |
2008-05-16 |
Novartis Ag |
Sal de maleato de 5-amino-3-(2',3'-di-o-acetil-beta-d-ribofuranosil)-3h-tiazolo[4,5-d]pirimidin-2-ona; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de una infeccion po
|
WO2008005542A2
(en)
|
2006-07-07 |
2008-01-10 |
Gilead Sciences, Inc., |
Antiviral phosphinate compounds
|
ATE499940T1
(de)
|
2006-07-18 |
2011-03-15 |
Anadys Pharmaceuticals Inc |
Carbonat- und carbamat-prodrugs von thiazolo ä4,5-dü-pyrimidinen
|
US20080161324A1
(en)
|
2006-09-14 |
2008-07-03 |
Johansen Lisa M |
Compositions and methods for treatment of viral diseases
|
US7879806B2
(en)
|
2006-11-06 |
2011-02-01 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzonitrile derivates, medicaments containing such compounds, their use and process for their manufacture
|
US8148349B2
(en)
|
2006-12-20 |
2012-04-03 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside cyclic phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
US7951789B2
(en)
|
2006-12-28 |
2011-05-31 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
US8071568B2
(en)
|
2007-01-05 |
2011-12-06 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
EP2114980B1
(en)
|
2007-01-12 |
2012-06-27 |
BioCryst Pharmaceuticals, Inc. |
Antiviral nucleoside analogs
|
JP2010522241A
(ja)
|
2007-03-21 |
2010-07-01 |
ブリストル−マイヤーズ スクイブ カンパニー |
増殖性疾患、アレルギー性疾患、自己免疫疾患または炎症性疾患として有用な縮合ヘテロ環化合物
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
WO2008141079A1
(en)
|
2007-05-10 |
2008-11-20 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro [3 4-d] dioxolane compounds for use in the treatment of viral infections and cancer
|
CN100532388C
(zh)
|
2007-07-16 |
2009-08-26 |
郑州大学 |
2’-氟-4’-取代-核苷类似物、其制备方法及应用
|
BR122020008558B1
(pt)
|
2007-08-03 |
2021-11-03 |
Biotron Limited |
Composição, e, uso de uma composição
|
KR101502533B1
(ko)
|
2007-11-22 |
2015-03-13 |
에스케이케미칼주식회사 |
우수한 안정성을 갖는 택산 유도체 함유 주사제용동결건조 조성물 및 이의 제조방법
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
US8227431B2
(en)
|
2008-03-17 |
2012-07-24 |
Hetero Drugs Limited |
Nucleoside derivatives
|
US7863291B2
(en)
|
2008-04-23 |
2011-01-04 |
Bristol-Myers Squibb Company |
Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands
|
WO2009132135A1
(en)
|
2008-04-23 |
2009-10-29 |
Gilead Sciences, Inc. |
1' -substituted carba-nucleoside analogs for antiviral treatment
|
WO2010036407A2
(en)
|
2008-05-15 |
2010-04-01 |
Biocryst Pharmaceuticals, Inc. |
Antiviral nucleoside analogs
|
WO2010002877A2
(en)
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
JP2012513953A
(ja)
|
2008-09-23 |
2012-06-21 |
アルニラム ファーマスーティカルズ インコーポレイテッド |
付加環化を用いたモノマーおよびオリゴヌクレオチドの化学修飾
|
PT2719701T
(pt)
|
2009-02-10 |
2017-06-29 |
Gilead Sciences Inc |
Método para a preparação de ribósidos de tieno[3,4-d]pirimidin-7-ilo
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
EP2408306A4
(en)
|
2009-03-20 |
2012-11-07 |
Alios Biopharma Inc |
SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGUES
|
KR101763672B1
(ko)
|
2009-03-24 |
2017-08-01 |
바이오크리스트파마슈티컬즈,인코포레이티드 |
7―[(3r,4r)―3―하이드록시―4―하이드록시메틸―피롤리딘―1―일메틸]―3,5―디하이드로―피롤로[3,2―d]피리미딘―4―온의 유용한 약학적 염
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
MX2012000959A
(es)
|
2009-07-21 |
2012-03-06 |
Gilead Sciences Inc |
Inhibidores de los virus flaviviridae.
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
CR20190103A
(es)
|
2009-09-21 |
2019-09-19 |
Gilead Sciences Inc |
ANÁLOGOS DE CARBA-NUCLEÓSIDOS SUSTITUIDOS CON 2'-FLUORO PARA TRATAMIENTO ANTIVIRAL (Divisional 2012-0186)
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
NZ599404A
(en)
|
2009-09-21 |
2014-02-28 |
Gilead Sciences Inc |
Processes and intermediates for the preparation of 1’-substituted carba-nucleoside analogs
|
SG181757A1
(en)
|
2009-12-28 |
2012-07-30 |
Dev Center Biotechnology |
Novel pyrimidine compounds as mtor and pi3k inhibitors
|
WO2011100131A2
(en)
|
2010-01-28 |
2011-08-18 |
Alnylam Pharmacuticals, Inc. |
Monomers and oligonucleotides comprising cycloaddition adduct(s)
|
CN104017020B
(zh)
|
2010-03-31 |
2017-04-12 |
吉利德制药有限责任公司 |
核苷氨基磷酸酯
|
EP2609923B1
(en)
|
2010-03-31 |
2017-05-24 |
Gilead Pharmasset LLC |
Process for the crystallisation of (s)-isopropyl 2-(((s)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
MA34471B1
(fr)
|
2010-07-19 |
2013-08-01 |
Gilead Sciences Inc |
Procédés de préparation de promédicaments au phosphoramidate pur au plan diastéréomère
|
ES2524356T3
(es)
|
2010-07-22 |
2014-12-05 |
Gilead Sciences, Inc. |
Métodos y compuestos para tratar infecciones provocadas por virus Paramyxoviridae
|
TW201305185A
(zh)
|
2010-09-13 |
2013-02-01 |
Gilead Sciences Inc |
用於抗病毒治療之2’-氟取代之碳-核苷類似物
|
CA2807496C
(en)
|
2010-09-20 |
2019-01-22 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
KR20130110170A
(ko)
|
2010-09-22 |
2013-10-08 |
앨리오스 바이오파마 인크. |
치환된 뉴클레오타이드 유사체
|
US20130331404A1
(en)
|
2010-10-15 |
2013-12-12 |
Biocryst Pharmaceuticals, Inc. |
Methods and Compositions for Inhibition of Polymerase
|
CN103476770B
(zh)
|
2010-11-25 |
2017-02-15 |
拉蒂欧制药有限责任公司 |
阿法替尼盐和多晶型物
|
TW201701876A
(zh)
|
2010-12-20 |
2017-01-16 |
吉李德科學股份有限公司 |
治療c型肝炎病毒(hcv)之方法
|
WO2012142523A2
(en)
|
2011-04-13 |
2012-10-18 |
Gilead Sciences, Inc. |
1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
|
MX352604B
(es)
|
2011-05-13 |
2017-11-30 |
Zoetis Llc |
Composiciones inmunogenicas de la glucoproteina g de los virus hendra y nipah.
|
HUE036588T2
(hu)
|
2011-09-16 |
2018-07-30 |
Gilead Pharmasset Llc |
Eljárások HCV kezelésére
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
WO2013084165A1
(en)
|
2011-12-05 |
2013-06-13 |
Medivir Ab |
Hcv polymerase inhibitors
|
US20130143835A1
(en)
|
2011-12-05 |
2013-06-06 |
Medivir Ab |
HCV Polymerase Inhibitors
|
US8980865B2
(en)
|
2011-12-22 |
2015-03-17 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
NZ702744A
(en)
|
2012-05-22 |
2016-12-23 |
Idenix Pharmaceuticals Llc |
D-amino acid compounds for liver disease
|
ES2671478T3
(es)
|
2012-08-31 |
2018-06-06 |
Novartis Ag |
Derivados de 2'-etinil nucleósidos para el tratamiento de infecciones virales
|
CA2881322A1
(en)
|
2012-09-10 |
2014-03-13 |
F. Hoffmann-La Roche Ag |
6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2014042433A2
(en)
|
2012-09-14 |
2014-03-20 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating adenosine a3 receptor activity
|
CA2890905A1
(en)
|
2012-11-16 |
2014-05-22 |
Biocryst Pharmaceuticals, Inc. |
Antiviral azasugar-containing nucleosides
|
WO2014078463A1
(en)
|
2012-11-19 |
2014-05-22 |
Merck Sharp & Dohme Corp. |
2 -alkynyl substituted nucleoside derivatives for treating viral diseases
|
ES2865402T3
(es)
|
2012-12-21 |
2021-10-15 |
Janssen Biopharma Inc |
4'-fluoronucleósidos, 4'-fluoronucleótidos y análogos de los mismos para el tratamiento del VHC
|
US9283242B2
(en)
|
2013-01-22 |
2016-03-15 |
Massachusetts Institute Of Technology |
Uses of dihydro bases
|
US10034893B2
(en)
|
2013-02-01 |
2018-07-31 |
Enanta Pharmaceuticals, Inc. |
5, 6-D2 uridine nucleoside/tide derivatives
|
CN105377868A
(zh)
|
2013-04-12 |
2016-03-02 |
艾其林医药公司 |
用于治疗hcv的高活性核苷衍生物
|
US9815864B2
(en)
|
2013-06-26 |
2017-11-14 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
UA117375C2
(uk)
|
2013-09-04 |
2018-07-25 |
Медівір Аб |
Інгібітори полімерази hcv
|
KR101949251B1
(ko)
|
2013-09-11 |
2019-02-18 |
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) |
B형간염바이러스 감염의 치료 방법 및 치료용 약학적 조성물
|
SG11201602595TA
(en)
|
2013-10-11 |
2016-04-28 |
Alios Biopharma Inc |
Substituted nucleosides, nucleotides and analogs thereof
|
UA119050C2
(uk)
|
2013-11-11 |
2019-04-25 |
Ґілеад Саєнсиз, Інк. |
ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
|
PE20160686A1
(es)
|
2014-01-30 |
2016-07-23 |
Hoffmann La Roche |
Nuevas dihidroquinolizinonas para el tratamiento y profilaxis de la infeccion por virus de la hepatitis b
|
JP6306750B2
(ja)
|
2014-03-07 |
2018-04-04 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の治療および予防のための新規な6−縮合ヘテロアリールジヒドロピリミジン
|
RU2016146365A
(ru)
|
2014-05-13 |
2018-06-19 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b
|
US9616076B2
(en)
|
2014-06-02 |
2017-04-11 |
The Board Of Regents Of The University Of Texas Systems |
Methods for treating viral infections using hydrogen sulfide donors
|
US9504701B2
(en)
|
2014-06-02 |
2016-11-29 |
The Board Of Regents Of The University Of Texas System |
Methods for treating viral infections using hydrogen sulfide donors
|
LT3160476T
(lt)
|
2014-06-24 |
2021-04-12 |
Janssen Biopharma, Inc. |
Pakeistieji nukleozidai, nukleotidai ir jų analogai, skirti naudoti virusinių infekcijų gydyme
|
AU2015280234B2
(en)
|
2014-06-24 |
2021-04-01 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
WO2016012470A1
(en)
|
2014-07-25 |
2016-01-28 |
F. Hoffmann-La Roche Ag |
New amorphous and crystalline forms of (3s)-4-[[(4r)-4-(2-chloro-4-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
|
CN106573898B
(zh)
|
2014-08-14 |
2018-11-09 |
豪夫迈·罗氏有限公司 |
治疗和预防乙型肝炎病毒感染的新的哒嗪酮和三嗪酮
|
TWI698444B
(zh)
|
2014-10-29 |
2020-07-11 |
美商基利科學股份有限公司 |
製備核糖苷的方法
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
WO2016102438A1
(en)
|
2014-12-23 |
2016-06-30 |
F. Hoffmann-La Roche Ag |
Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidine analogues
|
US9676793B2
(en)
|
2014-12-23 |
2017-06-13 |
Hoffmann-Laroche Inc. |
Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
|
EP3240537B1
(en)
|
2014-12-30 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2016107833A1
(en)
|
2014-12-31 |
2016-07-07 |
F. Hoffmann-La Roche Ag |
A novel high-throughput method for quantification of hbv cccdna from cell lysate by real-time pcr
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
WO2016120186A1
(en)
|
2015-01-27 |
2016-08-04 |
F. Hoffmann-La Roche Ag |
Recombinant hbv cccdna, the method to generate thereof and the use thereof
|
CN107207505B
(zh)
|
2015-02-11 |
2018-12-14 |
豪夫迈·罗氏有限公司 |
治疗和预防乙型肝炎病毒感染的 2-氧代-6,7-二氢苯并[a]喹嗪-3-甲酸衍生物
|
ES2918585T3
(es)
|
2015-09-16 |
2022-07-19 |
Gilead Sciences Inc |
Métodos para el tratamiento de infecciones por el virus Arenaviridae
|
WO2017165489A1
(en)
|
2016-03-23 |
2017-09-28 |
Emory University |
Antiviral agents for treating zika and dengue virus infections
|
WO2017184668A1
(en)
|
2016-04-20 |
2017-10-26 |
Gilead Sciences, Inc. |
Methods for treating flaviviridae virus infections
|
US11021510B2
(en)
|
2016-11-03 |
2021-06-01 |
Laurence I. Wu |
Prodrugs of clofarabine
|
CN108299532B
(zh)
|
2016-12-29 |
2020-12-22 |
广东东阳光药业有限公司 |
一种抗病毒核苷类似物前药及其组合物、用途
|
EP3579833B1
(en)
|
2017-02-08 |
2022-01-05 |
Biotron Limited |
Methods of treating influenza
|
US10682368B2
(en)
|
2017-03-14 |
2020-06-16 |
Gilead Sciences, Inc. |
Methods of treating feline coronavirus infections
|
CA3178212A1
(en)
|
2017-05-01 |
2018-11-08 |
Gilead Sciences, Inc. |
Crystalline forms of (s)-2-ethylbutyl 2-(((s)-(((2r,3s,4r,5r)-5-(4-aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy) phosphoryl)amino)propanoate
|
WO2018217906A1
(en)
|
2017-05-23 |
2018-11-29 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dengue virus serotype 4 epitopes
|
US10675296B2
(en)
|
2017-07-11 |
2020-06-09 |
Gilead Sciences, Inc. |
Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
|
US20190023745A1
(en)
|
2017-07-19 |
2019-01-24 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for zika virus vaccines
|
EA202090775A1
(ru)
|
2017-09-18 |
2020-07-06 |
Янссен Байофарма, Инк. |
Замещенные нуклеозиды, нуклеотиды и их аналоги
|
US11566050B2
(en)
|
2017-10-18 |
2023-01-31 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for norovirus vaccines and diagnostics
|
WO2021021717A1
(en)
|
2019-07-27 |
2021-02-04 |
Brii Biosciences, Inc. |
Adenosine derivative and pharmaceutical composition comprising the same
|
CN110330540A
(zh)
|
2019-08-08 |
2019-10-15 |
木天(济南)生物科技有限公司 |
核苷盐及其制备方法
|
WO2021040356A1
(en)
|
2019-08-23 |
2021-03-04 |
Kainos Medicine, Inc. |
C-nucleosides, c-nucleotides and their analogs, equivalents and prodrugs thereof for ectonucleotidase inhibition
|
CN110724174B
(zh)
|
2019-09-10 |
2021-02-05 |
广州六顺生物科技股份有限公司 |
吡咯并三嗪类化合物、组合物及其应用
|
CN114793421A
(zh)
|
2019-09-11 |
2022-07-26 |
斯克里普斯研究所 |
抗病毒前体药物及其药物组合物
|
WO2021102363A1
(en)
|
2019-11-20 |
2021-05-27 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for recombinant dengue viruses for vaccine and diagnostic development
|
CN110776512A
(zh)
|
2019-11-28 |
2020-02-11 |
成都傲飞生物化学品有限责任公司 |
一种核苷类似物的制备方法
|
CN111265532A
(zh)
|
2020-01-21 |
2020-06-12 |
中国人民解放军军事科学院军事医学研究院 |
取代氨基丙酸酯类化合物在治疗2019-nCoV感染中的应用
|
KR20220132608A
(ko)
|
2020-01-27 |
2022-09-30 |
길리애드 사이언시즈, 인코포레이티드 |
SARS CoV-2 감염증을 치료하기 위한 방법
|
WO2021154530A1
(en)
|
2020-01-27 |
2021-08-05 |
Vanderbilt University |
Human anti-dengue antibodies and methods of use therefor
|
CN113248508A
(zh)
|
2020-02-13 |
2021-08-13 |
安徽诺全药业有限公司 |
N-保护的杂环类化合物、其制备方法及其用于制备c-核苷衍生物的方法
|
CN111205327B
(zh)
|
2020-02-17 |
2022-05-31 |
南京法恩化学有限公司 |
一种瑞德西韦的制备方法
|
TW202315607A
(zh)
|
2020-02-18 |
2023-04-16 |
美商基利科學股份有限公司 |
抗病毒化合物
|
CN113292565B
(zh)
|
2020-02-24 |
2023-01-31 |
浙江森科建设有限公司 |
核苷类化合物及其制备方法和应用
|
CN111205294B
(zh)
|
2020-02-27 |
2021-10-01 |
江苏阿尔法药业股份有限公司 |
一种瑞德西韦中间体的制备方法
|
CN111171078B
(zh)
|
2020-02-27 |
2022-04-22 |
江苏阿尔法药业股份有限公司 |
一种瑞德西韦的合成方法
|
CN113354699B
(zh)
|
2020-03-04 |
2023-07-18 |
中国科学院上海药物研究所 |
瑞德西韦的中间体及其制备方法
|
CN113387954B
(zh)
|
2020-03-11 |
2024-03-19 |
上海特化医药科技有限公司 |
一种瑞德西韦中间体的制备方法
|
CN111233869B
(zh)
|
2020-03-12 |
2022-09-16 |
杭州新博思生物医药有限公司 |
用于制备瑞德西韦关键中间体的新化合物及其制备方法
|
JP2023516087A
(ja)
|
2020-03-12 |
2023-04-17 |
ギリアード サイエンシーズ, インコーポレイテッド |
1’-シアノヌクレオシドを調製する方法
|
US20230137667A1
(en)
|
2020-03-19 |
2023-05-04 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for treatment of coronavirus infection
|
IL296152A
(en)
|
2020-03-23 |
2022-11-01 |
John M H Gregg |
Antiviral compounds and methods of their administration
|
CN111548384B
(zh)
|
2020-03-29 |
2021-04-27 |
常州安蒂卫生物科技有限公司 |
用于抗病毒治疗的被取代的n4-羟基胞苷衍生物及其前药
|
US20230183282A1
(en)
*
|
2020-04-02 |
2023-06-15 |
The Regents Of The University Of Michigan |
Remdesivir and remdesivir analogs, solutions, and nanoparticle, liposomal, and microparticle compositions for treating viral infections
|
CA3172483A1
(en)
|
2020-04-06 |
2021-10-14 |
Scott Ellis |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
CN112778310A
(zh)
|
2020-04-20 |
2021-05-11 |
中国科学院上海药物研究所 |
核苷类似物或含有核苷类似物的组合制剂在抗病毒中的应用
|
CN111440176B
(zh)
|
2020-04-28 |
2022-04-26 |
江苏大学 |
金属配合物促进的瑞德西韦中间体的合成方法
|
WO2021222807A1
(en)
|
2020-04-30 |
2021-11-04 |
Ajk Pharmaceutical Llc |
Fatty acyl and fatty ether conjugates of remdesivir and its active metabolites as antivirals
|
CN111961057A
(zh)
|
2020-05-26 |
2020-11-20 |
李小冬 |
一种α构型核苷及其在治疗猫冠状病毒感染的应用
|
AU2021281351A1
(en)
|
2020-05-29 |
2023-01-19 |
Gilead Sciences, Inc. |
Remdesivir treatment methods
|
WO2021248229A1
(en)
|
2020-06-11 |
2021-12-16 |
Apotex Inc |
Novel crystalline form of remdesivir
|
PE20230618A1
(es)
|
2020-06-24 |
2023-04-14 |
Gilead Sciences Inc |
Analogos de nucleosido de 1'-ciano y usos de los mismos
|
WO2022008642A1
(en)
|
2020-07-08 |
2022-01-13 |
Apeiron Biologics Ag |
Treatment of sars-cov-2 infection with a combination of targets
|
EP4192839A1
(en)
|
2020-08-06 |
2023-06-14 |
Richter Gedeon Nyrt. |
Remdesivir intermediates
|
IL300453A
(en)
|
2020-08-27 |
2023-04-01 |
Gilead Sciences Inc |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS
|
KR20230058107A
(ko)
|
2020-08-28 |
2023-05-02 |
세이바 파마슈티컬스 인크. |
항바이러스 화합물 제형
|
US11225508B1
(en)
|
2020-09-23 |
2022-01-18 |
The University Of North Carolina At Chapel Hill |
Mouse-adapted SARS-CoV-2 viruses and methods of use thereof
|
US20230381293A1
(en)
|
2020-10-14 |
2023-11-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic |
Stabilized norovirus virus-like particles as vaccine immunogens
|
US20240018191A1
(en)
|
2020-10-27 |
2024-01-18 |
The University Of North Carolina At Chapel Hill |
Chimeric coronavirus s protein compositions and methods of use
|
WO2022098371A1
(en)
|
2020-11-09 |
2022-05-12 |
Yan Matthew |
Prodrugs of 1'-substituted carba-nucleoside analogues for antiviral treatment
|
CN114621229A
(zh)
|
2020-12-11 |
2022-06-14 |
嘉兴金派特生物科技有限公司 |
治疗或预防猫传染性腹膜炎的化合物或组合物
|
CN116370479B
(zh)
|
2020-12-30 |
2024-02-13 |
南方科技大学 |
化合物atv014在制备用于治疗新冠病毒感染的产品中的用途
|
CN113754665B
(zh)
|
2020-12-30 |
2022-08-19 |
南方科技大学 |
一种核苷类化合物的制备方法
|
WO2022165386A1
(en)
|
2021-01-29 |
2022-08-04 |
Virbis Llc |
Lnp and lmp delivery of antiviral nucleotide 5'-phosphates
|
WO2022174194A1
(en)
|
2021-02-15 |
2022-08-18 |
Emory University |
4'-halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto
|
WO2022197950A1
(en)
|
2021-03-17 |
2022-09-22 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for mature dengue viruses as vaccines and diagnostics
|
IL307478A
(en)
|
2021-04-09 |
2023-12-01 |
Univ Emory |
Thionucleosides as antiviral agents
|
US20240166680A1
(en)
|
2021-04-15 |
2024-05-23 |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences |
Nucleoside analog and use thereof
|
EP4328227A1
(en)
|
2021-04-23 |
2024-02-28 |
Vigonvita Life Sciences Co., Ltd. |
Nucleoside compound and application thereof in the treatment of feline infectious peritonitis
|
CN113185519A
(zh)
|
2021-04-23 |
2021-07-30 |
苏州富德兆丰生化科技有限公司 |
一种核苷类化合物及其在治疗猫传染性腹膜炎中的应用
|
WO2022251663A2
(en)
|
2021-05-27 |
2022-12-01 |
Emory University |
Novel universal anti-rna virus agents
|
CN113698405B
(zh)
|
2021-06-03 |
2022-09-27 |
南方科技大学坪山生物医药研究院 |
一种核苷类化合物的晶型及其制备方法
|
TW202317144A
(zh)
|
2021-06-14 |
2023-05-01 |
美商維納拓爾斯製藥公司 |
口服生物可利用的核苷類似物
|
US11541071B1
(en)
|
2021-12-16 |
2023-01-03 |
Ascletis BioScience Co., Ltd |
Nucleoside derivatives and methods of use thereof
|
CN114437159B
(zh)
|
2022-04-11 |
2022-06-28 |
佛山市晨康生物科技有限公司 |
一种环状碳酸酯核苷类化合物及其应用
|