US4816570A
(en)
|
1982-11-30 |
1989-03-28 |
The Board Of Regents Of The University Of Texas System |
Biologically reversible phosphate and phosphonate protective groups
|
US4968788A
(en)
|
1986-04-04 |
1990-11-06 |
Board Of Regents, The University Of Texas System |
Biologically reversible phosphate and phosphonate protective gruops
|
JP3347723B2
(ja)
|
1990-06-13 |
2002-11-20 |
グラツィエル,アーノルド |
含リンプロドラッグ
|
DE10399025I2
(de)
|
1990-09-14 |
2007-11-08 |
Acad Of Science Czech Republic |
Wirkstoffvorläufer von Phosphonaten
|
US6887707B2
(en)
|
1996-10-28 |
2005-05-03 |
University Of Washington |
Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA
|
AU3247899A
(en)
|
1998-03-03 |
1999-09-20 |
Novo Nordisk A/S |
New salt forms of (2e)- 5-amino-5- methylhex-2- enoic acid n-methyl-n-((1r)-1-(n- methyl-n-((1r)-1-(methylcarbamoyl)-2- phenylethyl)carbamoyl)-2- (2-naphtyl)ethyl)amide
|
US6312662B1
(en)
|
1998-03-06 |
2001-11-06 |
Metabasis Therapeutics, Inc. |
Prodrugs phosphorus-containing compounds
|
WO1999049873A1
(en)
|
1998-03-27 |
1999-10-07 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
DE69936998T2
(de)
|
1998-10-16 |
2008-05-21 |
Merck Sharp & Dohme Ltd., Hoddesdon |
Pyrazolotriazinderivate als gaba-rezeptorliganden
|
DE19912636A1
(de)
|
1999-03-20 |
2000-09-21 |
Aventis Cropscience Gmbh |
Bicyclische Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und pharmazeutische Mittel
|
JP2003514766A
(ja)
|
1999-06-03 |
2003-04-22 |
アボット・ラボラトリーズ |
活性剤としてルイス酸を用いるオリゴヌクレオチド合成
|
AUPQ105499A0
(en)
|
1999-06-18 |
1999-07-08 |
Biota Scientific Management Pty Ltd |
Antiviral agents
|
WO2001019375A1
(en)
|
1999-09-15 |
2001-03-22 |
Biocryst Pharmaceuticals, Inc. |
Inhibiting t-cell proliferation
|
WO2001032153A2
(en)
|
1999-11-04 |
2001-05-10 |
Shire Biochem Inc. |
Method for the treatment or prevention of flaviviridae viral infection using nucleoside analogues
|
NZ521210A
(en)
|
2000-02-18 |
2004-11-26 |
Shire Biochem Inc |
Method for the treatment or prevention of flavivirus infections using nucleoside analogues
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
NZ547204A
(en)
|
2000-05-26 |
2008-01-31 |
Idenix Cayman Ltd |
Methods and compositions for treating flaviviruses and pestiviruses
|
MXPA02011641A
(es)
|
2000-05-26 |
2004-07-30 |
Idenix Cayman Ltd |
Metodos para tatar infecciones por viurs de hepatitis delta con beta-l-2'-desoxi-nucleosidos.
|
KR100767432B1
(ko)
|
2000-07-21 |
2007-10-17 |
길리애드 사이언시즈, 인코포레이티드 |
포스포네이트 뉴클레오티드 유사체의 전구 약물과 그것의 선택 및 제조 방법
|
US20030008841A1
(en)
|
2000-08-30 |
2003-01-09 |
Rene Devos |
Anti-HCV nucleoside derivatives
|
PT1411954E
(pt)
|
2000-10-18 |
2011-03-16 |
Pharmasset Inc |
Nucleosídeos modificados para o tratamento de infecções virais e proliferação celular anormal
|
AUPR213700A0
(en)
|
2000-12-18 |
2001-01-25 |
Biota Scientific Management Pty Ltd |
Antiviral agents
|
MY134070A
(en)
|
2001-01-22 |
2007-11-30 |
Isis Pharmaceuticals Inc |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
DE10145223A1
(de)
|
2001-09-13 |
2003-04-03 |
Basf Ag |
Verfahren zur Herstellung von meso-Zeaxanthin
|
JP2005536440A
(ja)
|
2001-09-28 |
2005-12-02 |
イデニクス(ケイマン)リミテツド |
4’位が修飾されたヌクレオシドを使用するフラビウイルスおよびペスチウイルスの治療のための方法および組成物
|
AT410792B
(de)
|
2001-12-28 |
2003-07-25 |
Dsm Fine Chem Austria Gmbh |
Verfahren zur herstellung von geschützten, enantiomeren-angereicherten cyanhydrinen durch in-situ-derivatisierung
|
WO2003073989A2
(en)
|
2002-02-28 |
2003-09-12 |
Biota, Inc. |
Nucleoside 5'-monophosphate mimics and their prodrugs
|
WO2003072757A2
(en)
|
2002-02-28 |
2003-09-04 |
Biota, Inc. |
Nucleotide mimics and their prodrugs
|
US20040138170A1
(en)
|
2002-03-06 |
2004-07-15 |
Montgomery John A. |
Nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
GB0210124D0
(en)
|
2002-05-02 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB0210127D0
(en)
|
2002-05-02 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
KR20050006221A
(ko)
|
2002-05-06 |
2005-01-15 |
제네랩스 테크놀로지스, 인코포레이티드 |
C형 간염 바이러스 감염 치료용의 뉴클레오시드 유도체
|
WO2003100009A2
(en)
|
2002-05-23 |
2003-12-04 |
Biocryst Pharmaceuticals, Inc. |
Enhancing the efficacy of reverse transcriptase and dna polymerase inhibitors (nucleoside analogs) using pnp inhibitors and/or 2'-deoxyguanosine and/or prodrug thereof
|
HUE033832T2
(en)
|
2002-11-15 |
2018-01-29 |
Idenix Pharmaceuticals Llc |
2'-methyl nucleosides in combination with interferon and Flaviviridae mutation
|
TWI332507B
(en)
|
2002-11-19 |
2010-11-01 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
ATE490788T1
(de)
|
2003-04-25 |
2010-12-15 |
Gilead Sciences Inc |
Antivirale phosphonate analoge
|
EP2617709B8
(en)
|
2003-06-26 |
2022-12-21 |
Biotron Limited |
Guanidine derivatives as antiviral agents
|
GB0317009D0
(en)
|
2003-07-21 |
2003-08-27 |
Univ Cardiff |
Chemical compounds
|
AU2004258750A1
(en)
|
2003-07-25 |
2005-02-03 |
Centre National De La Recherche Scientifique -Cnrs |
Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis C
|
KR20060123707A
(ko)
|
2003-08-27 |
2006-12-04 |
바이오타, 인코포레이티드 |
치료제로서의 신규 트리시클릭 뉴클레오시드 또는뉴클레오티드
|
JP2005185235A
(ja)
|
2003-12-26 |
2005-07-14 |
Univ Of Tokyo |
ウイルス感染に対する感受性診断のための方法およびキット。
|
JP2005187428A
(ja)
|
2003-12-26 |
2005-07-14 |
Univ Of Tokyo |
抗mgl抗体によるフィロウイルス治療薬
|
CA2557801C
(en)
|
2004-03-16 |
2013-06-25 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof
|
WO2005123087A2
(en)
|
2004-06-15 |
2005-12-29 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
WO2006002231A1
(en)
|
2004-06-22 |
2006-01-05 |
Biocryst Pharmaceuticals, Inc. |
Aza nucleosides, preparation thereof and use as inhibitors of rna viral polymerases
|
MX2007003085A
(es)
|
2004-09-14 |
2007-08-02 |
Pharmasset Inc |
Preparacion de 2'-fluoro-2'-alquilo sustituido u otras ribofuranosil pirimidinas y purinas opcionalmente sustituidas y sus derivados.
|
US20080280842A1
(en)
|
2004-10-21 |
2008-11-13 |
Merck & Co., Inc. |
Fluorinated Pyrrolo[2,3-D]Pyrimidine Nucleosides for the Treatment of Rna-Dependent Rna Viral Infection
|
JP5089395B2
(ja)
|
2004-10-29 |
2012-12-05 |
バイオクライスト ファーマシューティカルズ, インコーポレイテッド |
治療用フロピリミジンおよびチエノピリミジン
|
WO2006064033A2
(en)
|
2004-12-16 |
2006-06-22 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
AU2006222563A1
(en)
|
2005-03-08 |
2006-09-14 |
Biota Scientific Management Pty Ltd. |
Bicyclic nucleosides and nucleotides as therapeutic agents
|
US7514410B2
(en)
|
2005-03-29 |
2009-04-07 |
Biocryst Pharmaceuticals, Inc. |
Hepatitis C therapies
|
WO2006116557A1
(en)
|
2005-04-25 |
2006-11-02 |
Genelabs Technologies, Inc. |
Nucleoside compounds for treating viral infections
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
WO2007027248A2
(en)
|
2005-05-16 |
2007-03-08 |
Valeant Research & Development |
3', 5' - cyclic nucleoside analogues for treatment of hcv
|
BRPI0612309B8
(pt)
|
2005-06-24 |
2021-05-25 |
Biotron Ltd |
compostos e composições farmacêuticas antivirais
|
CN101321775B
(zh)
|
2005-10-03 |
2012-05-23 |
大学健康网络 |
用于治疗疟疾的odcase抑制剂
|
WO2007056170A2
(en)
|
2005-11-02 |
2007-05-18 |
Bayer Healthcare Ag |
Pyrrolo[2,1-f] [1,2,4] triazin-4-ylamines igf-1r kinase inhibitors for the treatment of cancer and other hyperproliferative diseases
|
NO20055456L
(no)
|
2005-11-17 |
2007-05-18 |
Fluens Synthesis As |
Kontinuerlig stromningsreaktor
|
WO2007062542A2
(en)
|
2005-12-01 |
2007-06-07 |
Basilea Pharmaceutica Ag |
Process for the manufacture of epoxybutanol intermediates
|
PE20070855A1
(es)
|
2005-12-02 |
2007-10-14 |
Bayer Pharmaceuticals Corp |
Derivados de 4-amino-pirrolotriazina sustituida como inhibidores de quinasas
|
WO2007064931A2
(en)
|
2005-12-02 |
2007-06-07 |
Bayer Healthcare Llc |
Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
|
JP5112328B2
(ja)
|
2005-12-09 |
2013-01-09 |
バジリア ファルマスーチカ アーゲー |
重度の皮膚科障害の局所的処置のための4−オキソ(イソ)トレチノイン
|
MY150667A
(en)
|
2005-12-09 |
2014-02-28 |
Gilead Pharmasset Llc |
Antiviral nucleosides
|
JP2009526850A
(ja)
*
|
2006-02-14 |
2009-07-23 |
メルク エンド カムパニー インコーポレーテッド |
Rna依存性rnaウイルス感染を治療するためのヌクレオシドアリールホスホルアミデート
|
WO2007097991A2
(en)
|
2006-02-16 |
2007-08-30 |
Pharmasset, Inc. |
Methods and kits for dosing of antiviral agents
|
DE102006015378A1
(de)
|
2006-04-03 |
2007-10-04 |
Ludwig-Maximilians-Universität München |
Verfahren zur Synthese von Organoelementverbindungen
|
CL2007001427A1
(es)
|
2006-05-22 |
2008-05-16 |
Novartis Ag |
Sal de maleato de 5-amino-3-(2',3'-di-o-acetil-beta-d-ribofuranosil)-3h-tiazolo[4,5-d]pirimidin-2-ona; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de una infeccion po
|
WO2008005542A2
(en)
|
2006-07-07 |
2008-01-10 |
Gilead Sciences, Inc., |
Antiviral phosphinate compounds
|
DE602007012881D1
(en)
|
2006-07-18 |
2011-04-14 |
Anadys Pharmaceuticals Inc |
Carbonat- und carbamat-prodrugs von thiazolo ä4,5-dü-pyrimidinen
|
US20080161324A1
(en)
|
2006-09-14 |
2008-07-03 |
Johansen Lisa M |
Compositions and methods for treatment of viral diseases
|
WO2008055870A1
(en)
|
2006-11-06 |
2008-05-15 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzonitrile derivatives, medicaments containing such compounds, their use and process for their manufacture
|
AU2007338899A1
(en)
|
2006-12-20 |
2008-07-03 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside cyclic phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
US7951789B2
(en)
|
2006-12-28 |
2011-05-31 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
AU2007342367B2
(en)
|
2007-01-05 |
2012-12-06 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside aryl phosphoramidates for the treatment of RNA-dependent RNA viral infection
|
ES2390188T3
(es)
|
2007-01-12 |
2012-11-07 |
Biocryst Pharmaceuticals, Inc. |
Análogos de nucleósidos antivirales
|
EP2125819B1
(en)
|
2007-03-21 |
2014-10-22 |
Bristol-Myers Squibb Company |
Fused heterocyclic compounds useful for the treatment of proliferative, allergic, autoimmune or inflammatory diseases
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
DK2155758T3
(da)
|
2007-05-10 |
2012-11-05 |
Biocryst Pharm Inc |
Tetrahydrofuro[3,4-d]dioxolanforbindelser til anvendelse i behandlingen af virusinfektioner og cancer
|
CN100532388C
(zh)
|
2007-07-16 |
2009-08-26 |
郑州大学 |
2’-氟-4’-取代-核苷类似物、其制备方法及应用
|
CN101827589B
(zh)
|
2007-08-03 |
2016-08-17 |
拜伊特朗有限公司 |
抗丙型肝炎病毒的组合物及方法
|
KR101502533B1
(ko)
|
2007-11-22 |
2015-03-13 |
에스케이케미칼주식회사 |
우수한 안정성을 갖는 택산 유도체 함유 주사제용동결건조 조성물 및 이의 제조방법
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
US8227431B2
(en)
|
2008-03-17 |
2012-07-24 |
Hetero Drugs Limited |
Nucleoside derivatives
|
US7863291B2
(en)
|
2008-04-23 |
2011-01-04 |
Bristol-Myers Squibb Company |
Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands
|
PT2268642E
(pt)
|
2008-04-23 |
2015-06-02 |
Gilead Sciences Inc |
Análogos de carba-nulceósidos 1¿-substituídos para tratamento antiviral
|
WO2010036407A2
(en)
|
2008-05-15 |
2010-04-01 |
Biocryst Pharmaceuticals, Inc. |
Antiviral nucleoside analogs
|
EP2313102A2
(en)
|
2008-07-03 |
2011-04-27 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
EP3587434A1
(en)
|
2008-09-23 |
2020-01-01 |
Alnylam Pharmaceuticals Inc. |
Chemical modifications of monomers and oligonucleotides with click components for conjugation with ligands
|
ES2453078T3
(es)
|
2009-02-10 |
2014-04-03 |
Gilead Sciences, Inc. |
Análogos de carba-nucleósido para tratamiento antiviral
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
JP2012521359A
(ja)
|
2009-03-20 |
2012-09-13 |
アリオス バイオファーマ インク. |
置換されたヌクレオシドアナログおよびヌクレオチドアナログ
|
ES2519568T3
(es)
|
2009-03-24 |
2014-11-07 |
Biocryst Pharmaceuticals, Inc. |
Sales farmacéuticas útiles de 7-[(3R,4R)-3-hidroxi-4-hidroximetil-pirrolidin-1-ilmetil]-3,5-dihidro-pirrolo[3,2-d]pirimidin-4-ona
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
ES2427342T3
(es)
|
2009-07-21 |
2013-10-30 |
Gilead Sciences, Inc. |
Ácidos 5-alquiniltien-2-ilcarboxílicos como inhibidores de virus de los Flaviviridae
|
CA2773773C
(en)
|
2009-09-21 |
2019-04-23 |
Gilead Sciences, Inc. |
Processes and intermediates for the preparation of 1'-substituted carba-nucleoside analogs
|
PE20210668A1
(es)
|
2009-09-21 |
2021-04-05 |
Gilead Sciences Inc |
Analogos de carba-nucleosidos sustituidos con 2'-fluoro antivirales
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
SG181757A1
(en)
|
2009-12-28 |
2012-07-30 |
Dev Center Biotechnology |
Novel pyrimidine compounds as mtor and pi3k inhibitors
|
WO2011100131A2
(en)
|
2010-01-28 |
2011-08-18 |
Alnylam Pharmacuticals, Inc. |
Monomers and oligonucleotides comprising cycloaddition adduct(s)
|
JP5872539B2
(ja)
|
2010-03-31 |
2016-03-01 |
ギリアド ファーマセット エルエルシー |
プリンヌクレオシドホスホルアミダート
|
AU2011235112B2
(en)
|
2010-03-31 |
2015-07-09 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
JP5937073B2
(ja)
|
2010-07-19 |
2016-06-22 |
ギリード・サイエンシズ・インコーポレーテッド |
ジアステレオマーとして純粋なホスホルアミデートプロドラッグの調製方法
|
AU2011280910B2
(en)
|
2010-07-22 |
2015-07-09 |
Gilead Sciences, Inc. |
Methods and compounds for treating Paramyxoviridae virus infections
|
TW201305185A
(zh)
|
2010-09-13 |
2013-02-01 |
Gilead Sciences Inc |
用於抗病毒治療之2’-氟取代之碳-核苷類似物
|
CA2807496C
(en)
|
2010-09-20 |
2019-01-22 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
GEP20156313B
(en)
|
2010-09-22 |
2015-07-10 |
Alios Biopharma Inc |
Substituted nucleotide analogs
|
WO2012051570A1
(en)
|
2010-10-15 |
2012-04-19 |
Shanta Bantia |
Methods and compositions for inhibition of polymerase
|
EA024026B1
(ru)
|
2010-11-25 |
2016-08-31 |
Рациофарм Гмбх |
Новые соли и полиморфные формы афатиниба
|
US20130273005A1
(en)
|
2010-12-20 |
2013-10-17 |
Gilead Sciences, Inc. |
Methods for treating hcv
|
BR112013026219A2
(pt)
|
2011-04-13 |
2016-07-26 |
Gilead Sciences Inc |
análogos de n-nucleosídeo 1'-substituída pirimidina para tratamento antiviral
|
WO2012158643A1
(en)
|
2011-05-13 |
2012-11-22 |
Ah Usa 42 Llc |
Hendra and nipah virus g glycoprotein immunogenic compositions
|
NZ623396A
(en)
|
2011-09-16 |
2016-07-29 |
Gilead Pharmasset Llc |
Methods for treating hcv
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
US20130143835A1
(en)
|
2011-12-05 |
2013-06-06 |
Medivir Ab |
HCV Polymerase Inhibitors
|
WO2013084165A1
(en)
|
2011-12-05 |
2013-06-13 |
Medivir Ab |
Hcv polymerase inhibitors
|
EP2794630A4
(en)
|
2011-12-22 |
2015-04-01 |
Alios Biopharma Inc |
SUBSTITUTED PHOSPHORTHIOAT NUCLEOTIDE ANALOGUE
|
AU2013266393B2
(en)
|
2012-05-22 |
2017-09-28 |
Idenix Pharmaceuticals Llc |
D-amino acid compounds for liver disease
|
US9556216B2
(en)
|
2012-08-31 |
2017-01-31 |
Novartis Ag |
2′-Ethynyl nucleoside derivatives for treatment of viral infections
|
CA2881322A1
(en)
|
2012-09-10 |
2014-03-13 |
F. Hoffmann-La Roche Ag |
6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2014042433A2
(en)
|
2012-09-14 |
2014-03-20 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating adenosine a3 receptor activity
|
JP2016504284A
(ja)
|
2012-11-16 |
2016-02-12 |
バイオクリスト ファーマスーティカルズ,インコーポレイテッドBiocryst Pharmaceuticals,Inc. |
抗ウイルス性アザ糖を含有するヌクレオシド
|
CA2891125A1
(en)
|
2012-11-19 |
2014-05-22 |
Merck Sharp & Dohme Corp. |
2 -alkynyl substituted nucleoside derivatives for treating viral diseases
|
CA2894542C
(en)
|
2012-12-21 |
2023-10-31 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
US9283242B2
(en)
|
2013-01-22 |
2016-03-15 |
Massachusetts Institute Of Technology |
Uses of dihydro bases
|
US10034893B2
(en)
|
2013-02-01 |
2018-07-31 |
Enanta Pharmaceuticals, Inc. |
5, 6-D2 uridine nucleoside/tide derivatives
|
CN105705511A
(zh)
|
2013-04-12 |
2016-06-22 |
艾其林医药公司 |
用于治疗hcv的氘化核苷前药
|
EP3013340B9
(en)
|
2013-06-26 |
2023-10-04 |
Janssen Pharmaceuticals, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
UA117375C2
(uk)
|
2013-09-04 |
2018-07-25 |
Медівір Аб |
Інгібітори полімерази hcv
|
CA2923090C
(en)
|
2013-09-11 |
2018-08-21 |
Poxel |
Methods and pharmaceutical compositions for the treatment of hepatitis b virus infection
|
US9862743B2
(en)
|
2013-10-11 |
2018-01-09 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
UA119050C2
(uk)
|
2013-11-11 |
2019-04-25 |
Ґілеад Саєнсиз, Інк. |
ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
|
EA201691261A1
(ru)
|
2014-01-30 |
2016-11-30 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики инфекции, вызванной вирусом гепатита b
|
EA030115B9
(ru)
|
2014-03-07 |
2018-09-28 |
Ф. Хоффманн-Ля Рош Аг |
Новые 6-конденсированные гетероарилдигидропиримидины для лечения и профилактики заражения вирусом гепатита b
|
JP6568106B2
(ja)
|
2014-05-13 |
2019-08-28 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の治療及び予防のための新規ジヒドロキノリジノン類
|
US9504701B2
(en)
|
2014-06-02 |
2016-11-29 |
The Board Of Regents Of The University Of Texas System |
Methods for treating viral infections using hydrogen sulfide donors
|
US9616076B2
(en)
|
2014-06-02 |
2017-04-11 |
The Board Of Regents Of The University Of Texas Systems |
Methods for treating viral infections using hydrogen sulfide donors
|
EP3797782A1
(en)
|
2014-06-24 |
2021-03-31 |
Janssen BioPharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof for use in the treatment of viral infections
|
AP2016009653A0
(en)
|
2014-06-24 |
2016-12-31 |
Alios Biopharma Inc |
Substituted nucleosides, nucleotides and analogs thereof
|
WO2016012470A1
(en)
|
2014-07-25 |
2016-01-28 |
F. Hoffmann-La Roche Ag |
New amorphous and crystalline forms of (3s)-4-[[(4r)-4-(2-chloro-4-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
|
BR112017002970B1
(pt)
|
2014-08-14 |
2023-04-11 |
F. Hoffmann-La Roche Ag |
Novas piridazonas e triazinonas para o tratamento e profilaxia da infecção pelo vírus da hepatite b
|
TWI698444B
(zh)
|
2014-10-29 |
2020-07-11 |
美商基利科學股份有限公司 |
製備核糖苷的方法
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
US9676793B2
(en)
|
2014-12-23 |
2017-06-13 |
Hoffmann-Laroche Inc. |
Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
|
AR103222A1
(es)
|
2014-12-23 |
2017-04-26 |
Hoffmann La Roche |
Procedimiento para la preparación de análogos de 4-fenil-5-alcoxicarbonil-2-tiazol-2-il-1,4-dihidropirimidina
|
JP6506845B2
(ja)
|
2014-12-30 |
2019-04-24 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の治療及び予防のための新規テトラヒドロピリドピリミジン類及びテトラヒドロピリドピリジン類
|
CN107109497A
(zh)
|
2014-12-31 |
2017-08-29 |
豪夫迈·罗氏有限公司 |
通过实时PCR从细胞裂解物定量HBV cccDNA的高通量新方法
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
CN107208102B
(zh)
|
2015-01-27 |
2021-07-06 |
豪夫迈·罗氏有限公司 |
重组hbv cccdna、其产生方法及其用途
|
CN107207505B
(zh)
|
2015-02-11 |
2018-12-14 |
豪夫迈·罗氏有限公司 |
治疗和预防乙型肝炎病毒感染的 2-氧代-6,7-二氢苯并[a]喹嗪-3-甲酸衍生物
|
PT3785717T
(pt)
|
2015-09-16 |
2022-04-14 |
Gilead Sciences Inc |
Métodos para o tratamento de infeções por coronaviridae
|
WO2017165489A1
(en)
|
2016-03-23 |
2017-09-28 |
Emory University |
Antiviral agents for treating zika and dengue virus infections
|
WO2017184668A1
(en)
|
2016-04-20 |
2017-10-26 |
Gilead Sciences, Inc. |
Methods for treating flaviviridae virus infections
|
EP3529254B1
(en)
|
2016-11-03 |
2023-02-22 |
Laurence I. Wu |
Prodrugs of clofarabine
|
WO2018121678A1
(zh)
*
|
2016-12-29 |
2018-07-05 |
广东东阳光药业有限公司 |
一种抗病毒核苷类似物前药及其组合物、用途
|
US10918623B2
(en)
|
2017-02-08 |
2021-02-16 |
Biotron Limited |
Methods of treating influenza
|
ES2961460T3
(es)
|
2017-03-14 |
2024-03-12 |
Gilead Sciences Inc |
Métodos para tratar las infecciones por coronavirus felinas
|
AR111490A1
(es)
|
2017-05-01 |
2019-07-17 |
Gilead Sciences Inc |
Formas cristalinas de propanoato de (s)-2-etilbutil 2-(((s)-(((2r,3s,4r,5r)-5-(4-aminopirrolo[2,1-f][1,2,4]triazin-7-il)-5-ciano-3,4-dihidroxitetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)
|
US11241491B2
(en)
|
2017-05-23 |
2022-02-08 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dengue virus serotype 4 epitopes
|
CN111093627B
(zh)
|
2017-07-11 |
2024-03-08 |
吉利德科学公司 |
用于治疗病毒感染的包含rna聚合酶抑制剂和环糊精的组合物
|
US20190023745A1
(en)
|
2017-07-19 |
2019-01-24 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for zika virus vaccines
|
EP3684782A1
(en)
|
2017-09-18 |
2020-07-29 |
Janssen BioPharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
WO2019079594A1
(en)
|
2017-10-18 |
2019-04-25 |
The University Of North Carolina At Chapel Hill |
METHODS AND COMPOSITIONS FOR VACCINES AGAINST NOVOVIRUS AND DIAGNOSIS OF NOVOVIRUS
|
BR112022000965A2
(pt)
|
2019-07-27 |
2022-06-14 |
Brii Biosciences Inc |
Derivado de adenosina e composição farmacêutica que compreende o mesmo
|
CN110330540A
(zh)
|
2019-08-08 |
2019-10-15 |
木天(济南)生物科技有限公司 |
核苷盐及其制备方法
|
WO2021040356A1
(en)
|
2019-08-23 |
2021-03-04 |
Kainos Medicine, Inc. |
C-nucleosides, c-nucleotides and their analogs, equivalents and prodrugs thereof for ectonucleotidase inhibition
|
CN110724174B
(zh)
|
2019-09-10 |
2021-02-05 |
广州六顺生物科技股份有限公司 |
吡咯并三嗪类化合物、组合物及其应用
|
US20220332751A1
(en)
|
2019-09-11 |
2022-10-20 |
The Scripps Research Institute |
Antiviral prodrugs and pharmaceutical compositions thereof
|
US20230018080A1
(en)
|
2019-11-20 |
2023-01-19 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for recombinant dengue viruses or vaccine and diagnostic development
|
CN110776512A
(zh)
|
2019-11-28 |
2020-02-11 |
成都傲飞生物化学品有限责任公司 |
一种核苷类似物的制备方法
|
CN111265532A
(zh)
|
2020-01-21 |
2020-06-12 |
中国人民解放军军事科学院军事医学研究院 |
取代氨基丙酸酯类化合物在治疗2019-nCoV感染中的应用
|
WO2021154530A1
(en)
|
2020-01-27 |
2021-08-05 |
Vanderbilt University |
Human anti-dengue antibodies and methods of use therefor
|
CA3163424A1
(en)
|
2020-01-27 |
2021-08-05 |
Gilead Sciences, Inc. |
Methods for treating sars cov-2 infections
|
CN113248508A
(zh)
|
2020-02-13 |
2021-08-13 |
安徽诺全药业有限公司 |
N-保护的杂环类化合物、其制备方法及其用于制备c-核苷衍生物的方法
|
CN111205327B
(zh)
|
2020-02-17 |
2022-05-31 |
南京法恩化学有限公司 |
一种瑞德西韦的制备方法
|
TW202315607A
(zh)
|
2020-02-18 |
2023-04-16 |
美商基利科學股份有限公司 |
抗病毒化合物
|
CN113292565B
(zh)
|
2020-02-24 |
2023-01-31 |
浙江森科建设有限公司 |
核苷类化合物及其制备方法和应用
|
CN111205294B
(zh)
|
2020-02-27 |
2021-10-01 |
江苏阿尔法药业股份有限公司 |
一种瑞德西韦中间体的制备方法
|
CN111171078B
(zh)
|
2020-02-27 |
2022-04-22 |
江苏阿尔法药业股份有限公司 |
一种瑞德西韦的合成方法
|
WO2021175296A1
(zh)
|
2020-03-04 |
2021-09-10 |
中国科学院上海药物研究所 |
瑞德西韦的中间体及其制备方法
|
CN113387954B
(zh)
|
2020-03-11 |
2024-03-19 |
上海特化医药科技有限公司 |
一种瑞德西韦中间体的制备方法
|
CN111233869B
(zh)
|
2020-03-12 |
2022-09-16 |
杭州新博思生物医药有限公司 |
用于制备瑞德西韦关键中间体的新化合物及其制备方法
|
AU2021234308C1
(en)
|
2020-03-12 |
2024-02-22 |
Gilead Sciences, Inc. |
Methods of preparing 1'-cyano nucleosides
|
WO2021188915A1
(en)
|
2020-03-19 |
2021-09-23 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for treatment of coronavirus infection
|
IL296152A
(en)
|
2020-03-23 |
2022-11-01 |
John M H Gregg |
Antiviral compounds and methods of their administration
|
CN111548384B
(zh)
|
2020-03-29 |
2021-04-27 |
常州安蒂卫生物科技有限公司 |
用于抗病毒治疗的被取代的n4-羟基胞苷衍生物及其前药
|
US20230183282A1
(en)
*
|
2020-04-02 |
2023-06-15 |
The Regents Of The University Of Michigan |
Remdesivir and remdesivir analogs, solutions, and nanoparticle, liposomal, and microparticle compositions for treating viral infections
|
CN115362004A
(zh)
|
2020-04-06 |
2022-11-18 |
吉利德科学公司 |
1’-氰基取代的碳核苷类似物的吸入制剂
|
CN112778310A
(zh)
|
2020-04-20 |
2021-05-11 |
中国科学院上海药物研究所 |
核苷类似物或含有核苷类似物的组合制剂在抗病毒中的应用
|
CN111440176B
(zh)
|
2020-04-28 |
2022-04-26 |
江苏大学 |
金属配合物促进的瑞德西韦中间体的合成方法
|
US20230173077A1
(en)
|
2020-04-30 |
2023-06-08 |
AJK Biopharmaceutical, LLC |
Fatty acyl and fatty ether conjugates of remdesivir and its active metabolites as antivirals
|
CN111961057A
(zh)
|
2020-05-26 |
2020-11-20 |
李小冬 |
一种α构型核苷及其在治疗猫冠状病毒感染的应用
|
JP2023528810A
(ja)
|
2020-05-29 |
2023-07-06 |
ギリアード サイエンシーズ, インコーポレイテッド |
レムデシビル治療方法
|
CA3182179A1
(en)
|
2020-06-11 |
2021-12-16 |
Fabio E.S. Souza |
Novel crystalline form of remdesivir
|
EP4172160A2
(en)
|
2020-06-24 |
2023-05-03 |
Gilead Sciences, Inc. |
1'-cyano nucleoside analogs and uses thereof
|
WO2022008642A1
(en)
|
2020-07-08 |
2022-01-13 |
Apeiron Biologics Ag |
Treatment of sars-cov-2 infection with a combination of targets
|
CA3185450A1
(en)
|
2020-08-06 |
2022-02-10 |
Istvan Borza |
Remdesivir intermediates
|
TW202233204A
(zh)
|
2020-08-27 |
2022-09-01 |
美商基利科學股份有限公司 |
用於治療病毒感染之化合物及方法
|
AU2021334028A1
(en)
|
2020-08-28 |
2023-04-13 |
Sayvaa Pharmaceuticals Inc. |
Formulations of anti-viral compounds
|
US11225508B1
(en)
|
2020-09-23 |
2022-01-18 |
The University Of North Carolina At Chapel Hill |
Mouse-adapted SARS-CoV-2 viruses and methods of use thereof
|
US20230381293A1
(en)
|
2020-10-14 |
2023-11-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic |
Stabilized norovirus virus-like particles as vaccine immunogens
|
WO2022093895A1
(en)
|
2020-10-27 |
2022-05-05 |
The University Of North Carolina At Chapel Hill |
Chimeric coronavirus s protein compositions and methods of use
|
WO2022098371A1
(en)
|
2020-11-09 |
2022-05-12 |
Yan Matthew |
Prodrugs of 1'-substituted carba-nucleoside analogues for antiviral treatment
|
CN114621229A
(zh)
|
2020-12-11 |
2022-06-14 |
嘉兴金派特生物科技有限公司 |
治疗或预防猫传染性腹膜炎的化合物或组合物
|
JP2024503755A
(ja)
|
2020-12-30 |
2024-01-26 |
サウザン・ユニバーシティ・オブ・サイエンス・アンド・テクノロジー |
ウイルス感染症治療用ヌクレオシド系化合物及びその用途
|
CN113754665B
(zh)
|
2020-12-30 |
2022-08-19 |
南方科技大学 |
一种核苷类化合物的制备方法
|
WO2022165386A1
(en)
|
2021-01-29 |
2022-08-04 |
Virbis Llc |
Lnp and lmp delivery of antiviral nucleotide 5'-phosphates
|
WO2022174194A1
(en)
|
2021-02-15 |
2022-08-18 |
Emory University |
4'-halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto
|
WO2022197950A1
(en)
|
2021-03-17 |
2022-09-22 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for mature dengue viruses as vaccines and diagnostics
|
BR112023020798A2
(pt)
|
2021-04-09 |
2023-12-19 |
Univ Emory |
Método para tratar ou prevenir uma infecção, e, uso de um composto
|
US20240166680A1
(en)
|
2021-04-15 |
2024-05-23 |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences |
Nucleoside analog and use thereof
|
CN114765979A
(zh)
|
2021-04-23 |
2022-07-19 |
苏州旺山旺水生物医药有限公司 |
一种核苷类化合物及其在治疗猫传染性腹膜炎中的应用
|
CN113185519A
(zh)
|
2021-04-23 |
2021-07-30 |
苏州富德兆丰生化科技有限公司 |
一种核苷类化合物及其在治疗猫传染性腹膜炎中的应用
|
WO2022251663A2
(en)
|
2021-05-27 |
2022-12-01 |
Emory University |
Novel universal anti-rna virus agents
|
CN113698405B
(zh)
|
2021-06-03 |
2022-09-27 |
南方科技大学坪山生物医药研究院 |
一种核苷类化合物的晶型及其制备方法
|
EP4355755A1
(en)
|
2021-06-14 |
2024-04-24 |
Venatorx Pharmaceuticals, Inc. |
Orally-bioavailable nucleoside analogs
|
US11541071B1
(en)
|
2021-12-16 |
2023-01-03 |
Ascletis BioScience Co., Ltd |
Nucleoside derivatives and methods of use thereof
|
CN114437159B
(zh)
|
2022-04-11 |
2022-06-28 |
佛山市晨康生物科技有限公司 |
一种环状碳酸酯核苷类化合物及其应用
|