MX2009008495A - Novedosos analogos de nucleosidos para el tratamiento de infecciones virales. - Google Patents

Novedosos analogos de nucleosidos para el tratamiento de infecciones virales.

Info

Publication number
MX2009008495A
MX2009008495A MX2009008495A MX2009008495A MX2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A MX 2009008495 A MX2009008495 A MX 2009008495A
Authority
MX
Mexico
Prior art keywords
treatment
viral infections
nucleoside analogs
novel nucleoside
novel
Prior art date
Application number
MX2009008495A
Other languages
English (en)
Inventor
Jeyaraj Duraiswamy
Zheng Yin
Yen Liang Chen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39462074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009008495(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009008495A publication Critical patent/MX2009008495A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Abstract

Esta invención se refiere a novedosos compuestos de nucleósido de la fórmula (I) que tienen diferentes aplicaciones medicinales, por ejemplo, para el tratamiento y/o la prevención de infecciones virales. (ver fórmula (I)).
MX2009008495A 2007-02-09 2008-02-07 Novedosos analogos de nucleosidos para el tratamiento de infecciones virales. MX2009008495A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07102027 2007-02-09
EP08150003 2008-01-02
PCT/EP2008/051527 WO2008095993A1 (en) 2007-02-09 2008-02-07 Novel nucleoside analogs for treatment of viral infections

Publications (1)

Publication Number Publication Date
MX2009008495A true MX2009008495A (es) 2009-08-20

Family

ID=39462074

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008495A MX2009008495A (es) 2007-02-09 2008-02-07 Novedosos analogos de nucleosidos para el tratamiento de infecciones virales.

Country Status (18)

Country Link
US (1) US8278282B2 (es)
EP (1) EP2132216B1 (es)
JP (1) JP2010518047A (es)
KR (1) KR20090109102A (es)
CN (1) CN101600726B (es)
AR (1) AR065249A1 (es)
AT (1) ATE533774T1 (es)
AU (1) AU2008212752A1 (es)
BR (1) BRPI0807222A2 (es)
CA (1) CA2675462A1 (es)
CL (1) CL2008000409A1 (es)
EA (1) EA200901080A1 (es)
ES (1) ES2381093T3 (es)
MX (1) MX2009008495A (es)
PE (1) PE20090070A1 (es)
PT (1) PT2132216E (es)
TW (1) TW200838550A (es)
WO (1) WO2008095993A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072906A1 (es) * 2008-08-06 2010-09-29 Novartis Ag Nucleosidos modificados utiles como antivirales
CN102526087B (zh) * 2010-12-30 2014-09-03 南开大学 核苷类化合物在制备治疗肠病毒71(ev71)感染疾病药物的应用
CN105669783B (zh) * 2014-12-03 2019-11-12 广东东阳光药业有限公司 一种制备呋喃糖的方法
AU2016301188A1 (en) 2015-08-06 2018-02-15 Chimerix, Inc. Pyrrolopyrimidine nucleosides and analogs thereof useful as antiviral agents
WO2017053216A2 (en) 2015-09-23 2017-03-30 Merck Sharp & Dohme Corp. 4'-substituted nucleoside reverse transcriptase inhibitors and preparations thereof
WO2017189978A1 (en) * 2016-04-28 2017-11-02 Emory University Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto
TW201815821A (zh) * 2016-07-18 2018-05-01 美商再生元醫藥公司 抗茲卡病毒抗體及使用方法
US20190169221A1 (en) * 2016-08-12 2019-06-06 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US11111264B2 (en) 2017-09-21 2021-09-07 Chimerix, Inc. Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof
WO2020219447A1 (en) 2019-04-23 2020-10-29 Elementis Specialties, Inc. Slurry compositions containing mixed branched alkyl organoclay compositions
WO2023121362A1 (ko) * 2021-12-22 2023-06-29 씨제이제일제당 (주) 핵산 유래 뉴클레오사이드 아날로그 및 이들의 약학적으로 허용가능한 염을 포함하는 항바이러스용 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS50236B (sr) * 2001-01-22 2009-07-15 Merck & Co.Inc., Nukleozidni derivati kao inhibitori rnk-zavisne rnk virusne polimeraze
CA2469663A1 (en) 2001-12-14 2003-06-26 Alcon, Inc. Aminoalkyl-benzofuran-5-ol compounds for the treatment of glaucoma
US7323453B2 (en) * 2002-02-13 2008-01-29 Merck & Co., Inc. Methods of inhibiting orthopoxvirus replication with nucleoside compounds
MXPA04010983A (es) * 2002-05-06 2005-02-14 Genelabs Tech Inc Derivados de nucleosidos para tratar infecciones por el virus de la hepatitis c.
NZ538457A (en) * 2002-09-30 2008-04-30 Genelabs Tech Inc Nucleoside derivatives for treating hepatitis C virus infection
US20040259934A1 (en) * 2003-05-01 2004-12-23 Olsen David B. Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
CA2542776A1 (en) * 2003-10-27 2005-05-12 Genelabs Technologies, Inc. Nucleoside compounds for treating viral infections

Also Published As

Publication number Publication date
US20100227833A1 (en) 2010-09-09
ATE533774T1 (de) 2011-12-15
CN101600726B (zh) 2013-03-27
EP2132216B1 (en) 2011-11-16
AR065249A1 (es) 2009-05-27
AU2008212752A1 (en) 2008-08-14
JP2010518047A (ja) 2010-05-27
ES2381093T3 (es) 2012-05-23
PE20090070A1 (es) 2009-03-19
WO2008095993A1 (en) 2008-08-14
CN101600726A (zh) 2009-12-09
PT2132216E (pt) 2012-02-20
CL2008000409A1 (es) 2008-08-29
BRPI0807222A2 (pt) 2014-04-29
EA200901080A1 (ru) 2010-02-26
US8278282B2 (en) 2012-10-02
CA2675462A1 (en) 2008-08-14
KR20090109102A (ko) 2009-10-19
TW200838550A (en) 2008-10-01
EP2132216A1 (en) 2009-12-16

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