ATE533774T1 - Neuartige nukleosidanaloge zur behandlung von virusinfektionen - Google Patents

Neuartige nukleosidanaloge zur behandlung von virusinfektionen

Info

Publication number
ATE533774T1
ATE533774T1 AT08708805T AT08708805T ATE533774T1 AT E533774 T1 ATE533774 T1 AT E533774T1 AT 08708805 T AT08708805 T AT 08708805T AT 08708805 T AT08708805 T AT 08708805T AT E533774 T1 ATE533774 T1 AT E533774T1
Authority
AT
Austria
Prior art keywords
treatment
virus infections
nucleoside analogues
novel nucleoside
novel
Prior art date
Application number
AT08708805T
Other languages
English (en)
Inventor
Zheng Yin
Jeyaraj Duraiswamy
Yen Chen
Original Assignee
Novartis Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39462074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE533774(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Pharma Ag filed Critical Novartis Pharma Ag
Application granted granted Critical
Publication of ATE533774T1 publication Critical patent/ATE533774T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
AT08708805T 2007-02-09 2008-02-07 Neuartige nukleosidanaloge zur behandlung von virusinfektionen ATE533774T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07102027 2007-02-09
EP08150003 2008-01-02
PCT/EP2008/051527 WO2008095993A1 (en) 2007-02-09 2008-02-07 Novel nucleoside analogs for treatment of viral infections

Publications (1)

Publication Number Publication Date
ATE533774T1 true ATE533774T1 (de) 2011-12-15

Family

ID=39462074

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08708805T ATE533774T1 (de) 2007-02-09 2008-02-07 Neuartige nukleosidanaloge zur behandlung von virusinfektionen

Country Status (18)

Country Link
US (1) US8278282B2 (de)
EP (1) EP2132216B1 (de)
JP (1) JP2010518047A (de)
KR (1) KR20090109102A (de)
CN (1) CN101600726B (de)
AR (1) AR065249A1 (de)
AT (1) ATE533774T1 (de)
AU (1) AU2008212752A1 (de)
BR (1) BRPI0807222A2 (de)
CA (1) CA2675462A1 (de)
CL (1) CL2008000409A1 (de)
EA (1) EA200901080A1 (de)
ES (1) ES2381093T3 (de)
MX (1) MX2009008495A (de)
PE (1) PE20090070A1 (de)
PT (1) PT2132216E (de)
TW (1) TW200838550A (de)
WO (1) WO2008095993A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR072906A1 (es) * 2008-08-06 2010-09-29 Novartis Ag Nucleosidos modificados utiles como antivirales
CN102526087B (zh) * 2010-12-30 2014-09-03 南开大学 核苷类化合物在制备治疗肠病毒71(ev71)感染疾病药物的应用
CN105669783B (zh) * 2014-12-03 2019-11-12 广东东阳光药业有限公司 一种制备呋喃糖的方法
EP3331895B1 (de) 2015-08-06 2020-07-29 Chimerix, Inc. Pyrrolopyrimidin nucleoside und analaoga davon nützlich als antivirale mittel
CA2998646C (en) 2015-09-23 2021-05-18 Merck Sharp & Dohme Corp. 4'-substituted nucleoside reverse transcriptase inhibitors and preparations thereof
WO2017189978A1 (en) 2016-04-28 2017-11-02 Emory University Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto
TW201815821A (zh) * 2016-07-18 2018-05-01 美商再生元醫藥公司 抗茲卡病毒抗體及使用方法
WO2018031818A2 (en) * 2016-08-12 2018-02-15 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
WO2019060692A1 (en) 2017-09-21 2019-03-28 Chimerix, Inc. MORPHIC FORMS OF 4-AMINO-7- (3,4-DIHYDROXY-5- (HYDROXYMETHYL) -ETRAHYDROFURAN-2-YL) -2-METHYL-7H-PYRROLO [2,3-D] PYRIMIDINE-5-CARBOXAMIDE AND THEIR USES
US11718534B2 (en) 2019-04-23 2023-08-08 Elementis Specialties, Inc. Slurry compositions containing mixed branched alkyl organoclay compositions
WO2023121362A1 (ko) * 2021-12-22 2023-06-29 씨제이제일제당 (주) 핵산 유래 뉴클레오사이드 아날로그 및 이들의 약학적으로 허용가능한 염을 포함하는 항바이러스용 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1707571B1 (de) * 2001-01-22 2011-09-28 Merck Sharp & Dohme Corp. Nukleosidderivate als Inhibitoren der RNA-abhängigen viralen RNA-Polymerase
AU2002346671B2 (en) 2001-12-14 2005-08-11 Alcon, Inc. Aminoalkyl-benzofuran-5-OL compounds for the treatment of glaucoma
US7323453B2 (en) 2002-02-13 2008-01-29 Merck & Co., Inc. Methods of inhibiting orthopoxvirus replication with nucleoside compounds
AU2003232071A1 (en) * 2002-05-06 2003-11-17 Genelabs Technologies, Inc. Nucleoside derivatives for treating hepatitis c virus infection
EP1572097A4 (de) * 2002-09-30 2010-02-17 Smithkline Beecham Corp Nucleosid-derivate zur behandlung von infektionen mit dem hepatitis c-virus
US20040259934A1 (en) * 2003-05-01 2004-12-23 Olsen David B. Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
US7157434B2 (en) * 2003-10-27 2007-01-02 Genelabs Technologies, Inc. Nucleoside compounds for treating viral infections

Also Published As

Publication number Publication date
AR065249A1 (es) 2009-05-27
CL2008000409A1 (es) 2008-08-29
ES2381093T3 (es) 2012-05-23
CA2675462A1 (en) 2008-08-14
BRPI0807222A2 (pt) 2014-04-29
EP2132216B1 (de) 2011-11-16
TW200838550A (en) 2008-10-01
AU2008212752A1 (en) 2008-08-14
US20100227833A1 (en) 2010-09-09
CN101600726B (zh) 2013-03-27
PT2132216E (pt) 2012-02-20
US8278282B2 (en) 2012-10-02
WO2008095993A1 (en) 2008-08-14
EA200901080A1 (ru) 2010-02-26
EP2132216A1 (de) 2009-12-16
CN101600726A (zh) 2009-12-09
KR20090109102A (ko) 2009-10-19
PE20090070A1 (es) 2009-03-19
MX2009008495A (es) 2009-08-20
JP2010518047A (ja) 2010-05-27

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