MX2012002031A - Moleculas pequeñas que contienen boro como agentes antiprotozoarios. - Google Patents
Moleculas pequeñas que contienen boro como agentes antiprotozoarios.Info
- Publication number
- MX2012002031A MX2012002031A MX2012002031A MX2012002031A MX2012002031A MX 2012002031 A MX2012002031 A MX 2012002031A MX 2012002031 A MX2012002031 A MX 2012002031A MX 2012002031 A MX2012002031 A MX 2012002031A MX 2012002031 A MX2012002031 A MX 2012002031A
- Authority
- MX
- Mexico
- Prior art keywords
- boron
- small molecules
- containing small
- antiprotozoal agents
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
Abstract
La presente invención proporciona los nuevos compuestos de la siguiente fórmula, (ver fórmula) útiles para tratar infecciones por protozoarios, las composiciones farmacéuticas que contienen tales compuestos, así como las combinaciones de estos compuestos con al menos un agente terapéuticamente efectivo adicional.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23529609P | 2009-08-19 | 2009-08-19 | |
PCT/US2010/045639 WO2011022337A1 (en) | 2009-08-19 | 2010-08-16 | Boron-containing small molecules as antiprotozoal agents |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012002031A true MX2012002031A (es) | 2012-07-04 |
Family
ID=43383496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012002031A MX2012002031A (es) | 2009-08-19 | 2010-08-16 | Moleculas pequeñas que contienen boro como agentes antiprotozoarios. |
Country Status (4)
Country | Link |
---|---|
US (1) | US20110207701A1 (es) |
IL (1) | IL218163A0 (es) |
MX (1) | MX2012002031A (es) |
WO (1) | WO2011022337A1 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010045503A1 (en) * | 2008-10-15 | 2010-04-22 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-protozoal agents |
WO2011019618A1 (en) * | 2009-08-14 | 2011-02-17 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
US8623911B2 (en) * | 2010-03-19 | 2014-01-07 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-protozoal agent |
US9585396B2 (en) | 2013-01-30 | 2017-03-07 | Agrofresh Inc. | Volatile applications against pathogens |
US8669207B1 (en) | 2013-01-30 | 2014-03-11 | Dow Agrosciences, Llc. | Compounds and compositions |
JP5927686B1 (ja) * | 2013-01-30 | 2016-06-01 | アグロフレッシュ インコーポレイテッド | 食肉、植物または植物の一部分に対する揮発性抗菌剤としてのベンゾオキサボロールの使用 |
US11039617B2 (en) | 2013-01-30 | 2021-06-22 | Agrofresh Inc. | Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness |
US10070649B2 (en) | 2013-01-30 | 2018-09-11 | Agrofresh Inc. | Volatile applications against pathogens |
WO2015097237A1 (en) | 2013-12-23 | 2015-07-02 | Syngenta Participations Ag | Benzoxaborole fungicides |
US20170000133A1 (en) * | 2013-12-23 | 2017-01-05 | Syngenta Participations Ag | Benzoxaborole fungicides |
KR20170024068A (ko) | 2014-07-01 | 2017-03-06 | 다이이찌 산쿄 가부시키가이샤 | 항박테리아제로서의 삼환식 벤즈옥사보롤 |
AR103397A1 (es) * | 2015-01-13 | 2017-05-10 | Syngenta Participations Ag | Oxoborazoles microbicidas |
WO2017031041A1 (en) * | 2015-08-17 | 2017-02-23 | Channel Therapeutics, Inc. | Functionalized aminobenzoboroxoles |
CN106467557B (zh) * | 2015-08-18 | 2019-05-03 | 北京海美桐医药科技有限公司 | 他瓦硼罗的一种制备方法 |
EP3426029B1 (en) | 2016-03-07 | 2023-08-30 | AgroFresh Inc. | Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops |
US10961261B2 (en) | 2017-03-01 | 2021-03-30 | Anacor Pharmaceuticals, Inc. | Oxaborole analogs and uses thereof |
CN107090000B (zh) * | 2017-04-27 | 2019-07-12 | 上海交通大学 | 一种苯并硼唑7位脂肪酸的衍生物及其制备与用途 |
CN108191898B (zh) * | 2017-12-18 | 2020-08-25 | 上海交通大学 | 一种苯并硼唑7位查尔酮衍生物及其制备与应用 |
WO2019153324A1 (en) * | 2018-02-12 | 2019-08-15 | Shanghai Jiao Tong University | Derivatives of 7-fatty acid substituted benzoxaborole and their preparation and use |
WO2020186504A1 (en) * | 2019-03-21 | 2020-09-24 | Shanghai Jiao Tong University | A new type of antitumor compounds: derivatives of 7-propanamide substituted benzoxaborole |
CN111333672B (zh) * | 2020-04-07 | 2022-11-08 | 中国医学科学院放射医学研究所 | 一种固醇调控元件结合蛋白和酸性核质dna结合蛋白-1抑制剂及其制备方法和应用 |
WO2022043936A1 (en) | 2020-08-31 | 2022-03-03 | Pfizer Inc. | Methods of protecting rna |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2260336A (en) * | 1939-10-16 | 1941-10-28 | Dow Chemical Co | Method of preparation of organic borates |
GB1396904A (en) * | 1972-08-11 | 1975-06-11 | Ici Ltd | Method for the control of micro-organisms |
US4602011A (en) * | 1975-10-24 | 1986-07-22 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
US4766113A (en) * | 1975-10-24 | 1988-08-23 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
US4716035A (en) * | 1985-05-24 | 1987-12-29 | The Procter & Gamble Company | Oral compositions and methods for treating gingivitis |
US5962498A (en) * | 1986-06-11 | 1999-10-05 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity |
US4894220A (en) * | 1987-01-30 | 1990-01-16 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
SG47101A1 (en) * | 1992-07-31 | 1998-03-20 | Us Bioscience | Crystalline amifostine compositions and methods for the preparation and use of same |
US5348947A (en) * | 1993-05-07 | 1994-09-20 | American Cyanamid Company | Diarylboron ester and thioester fungicidal agents |
US5348948A (en) * | 1993-05-07 | 1994-09-20 | American Cyanamid Company | 2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal |
US5594151A (en) * | 1994-01-28 | 1997-01-14 | Prolinx, Inc. | Phenylboronic acid complexing reagents derived from aminosalicylic acid |
GB9411587D0 (en) * | 1994-06-09 | 1994-08-03 | Zeneca Ltd | Compound, composition and use |
US6083903A (en) * | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
US5831046A (en) * | 1996-08-05 | 1998-11-03 | Prolinx, Incorporated | Boronic acid-contaning nucleic acid monomers |
US6306628B1 (en) * | 1999-08-25 | 2001-10-23 | Ambergen, Incorporated | Methods for the detection, analysis and isolation of Nascent proteins |
US6521619B2 (en) * | 2000-06-29 | 2003-02-18 | Icos Corporation | Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents |
JP2004506417A (ja) * | 2000-07-14 | 2004-03-04 | ザイコス インク. | α−MSH関連化合物および使用方法 |
GB0117645D0 (en) * | 2001-07-19 | 2001-09-12 | Isis Innovation | Therapeutic stratergies for prevention and treatment of alzheimers disease |
DE10143979A1 (de) * | 2001-09-07 | 2003-03-27 | Clariant Gmbh | Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren |
US7217701B2 (en) * | 2001-10-11 | 2007-05-15 | Katsuhiko Mikoshiba | Intracellular calcium concentration increase inhibitors |
EP1980564A1 (en) * | 2002-12-18 | 2008-10-15 | Anacor Pharmaceuticals, Inc. | Antibiotics containing borinic acid complexes and methods of use |
US7390806B2 (en) * | 2002-12-18 | 2008-06-24 | Anacor Pharmaceuticals, Inc. | Antibiotics containing borinic acid complexes and methods of use |
US20050125852A1 (en) * | 2003-05-09 | 2005-06-09 | Sugen, Inc. | Novel kinases |
US7465836B2 (en) * | 2003-06-16 | 2008-12-16 | Anacor Pharmaceuticals, Inc. | Hydrolytically-resistant boron-containing therapeutics and methods of use |
EP1755661B1 (en) * | 2004-05-12 | 2014-03-12 | The Brigham And Women's Hospital, Inc. | Gelsolin for use in treating infections |
ES2872962T3 (es) | 2005-02-16 | 2021-11-03 | Anacor Pharmaceuticals Inc | Boronoftalidas para uso terapéutico |
US20060222671A1 (en) * | 2005-03-30 | 2006-10-05 | Astion Development A/S | Dermatological compositions and salts for the treatment of dermatological diseases |
CN106008571A (zh) * | 2005-12-30 | 2016-10-12 | 安纳考尔医药公司 | 含硼的小分子 |
KR101622870B1 (ko) | 2006-02-16 | 2016-05-19 | 아나코르 파마슈티칼스 인코포레이티드 | 항염증제로서 보론함유 소분자 |
US20070286822A1 (en) * | 2006-06-12 | 2007-12-13 | Anacor Pharmaceuticals Inc. | Compounds for the Treatment of Periodontal Disease |
JO3396B1 (ar) * | 2007-06-20 | 2019-10-20 | Anacor Pharmaceuticals Inc | جزيئات صغيرة تحتوي على البورون |
WO2009111676A2 (en) | 2008-03-06 | 2009-09-11 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules as anti-inflammatory agents |
EP2285384A4 (en) * | 2008-05-12 | 2012-04-25 | Anacor Pharmaceuticals Inc | BORN SMALL MOLECULES |
-
2010
- 2010-08-16 WO PCT/US2010/045639 patent/WO2011022337A1/en active Application Filing
- 2010-08-16 MX MX2012002031A patent/MX2012002031A/es not_active Application Discontinuation
- 2010-08-16 US US12/857,305 patent/US20110207701A1/en not_active Abandoned
-
2012
- 2012-02-16 IL IL218163A patent/IL218163A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2011022337A1 (en) | 2011-02-24 |
US20110207701A1 (en) | 2011-08-25 |
IL218163A0 (en) | 2012-07-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2012002031A (es) | Moleculas pequeñas que contienen boro como agentes antiprotozoarios. | |
MY162692A (en) | Boron-containing small molecules | |
WO2010027975A8 (en) | Boron-containing small molecules | |
GEP20135964B (en) | Inhibitors of beta-secretase | |
MY153915A (en) | Organic compounds | |
AU2016204248A1 (en) | Boron-Containing Molecules | |
MX2012001156A (es) | Moleculas que contienen boro trisustituidas. | |
MX2011005934A (es) | Compuestos organicos. | |
TN2012000559A1 (en) | Piperidinone derivatives as mdm2 inhibitors for the treatment of cancer | |
UA104885C2 (uk) | Ізотіазолілоксифеніламідини та їх застосування як фунгіцидів | |
MX2011009780A (es) | Pirimidinas sustituidas para el tratamiento del cancer. | |
NI200900151A (es) | Nuevo procedimiento de síntesis de la agomelatina. | |
MX2010003365A (es) | Derivados de tiazol para el tratamiento de cancer. | |
MX2012001413A (es) | Compuestos azaheterociclicos novedosos. | |
MX2012004780A (es) | Inhibidores de akt. | |
NI200900153A (es) | Nuevo procedimiento de síntesis de la agomelatina. | |
MX2009008495A (es) | Novedosos analogos de nucleosidos para el tratamiento de infecciones virales. | |
MX2011008195A (es) | Derivados de indol como agentes anticancer. | |
TN2011000355A1 (en) | Novel microbiocides | |
MX2010004604A (es) | Derivados de pirazol como inhibidores de 5-lo. | |
NI200900152A (es) | Nuevo procedimiento de síntesis de la agomelatina | |
MX2017012759A (es) | Moléculas pequeñas que contienen boro como agentes antiprotozoarios. | |
MX2009009074A (es) | Macrolidos basados en eritromicina. | |
IN2012DN01223A (es) | ||
MX2012004282A (es) | Composiciones farmaceuticas. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |