MX2017012759A - Moléculas pequeñas que contienen boro como agentes antiprotozoarios. - Google Patents

Moléculas pequeñas que contienen boro como agentes antiprotozoarios.

Info

Publication number
MX2017012759A
MX2017012759A MX2017012759A MX2017012759A MX2017012759A MX 2017012759 A MX2017012759 A MX 2017012759A MX 2017012759 A MX2017012759 A MX 2017012759A MX 2017012759 A MX2017012759 A MX 2017012759A MX 2017012759 A MX2017012759 A MX 2017012759A
Authority
MX
Mexico
Prior art keywords
boron
small molecules
containing small
antiprotozoal agents
compounds
Prior art date
Application number
MX2017012759A
Other languages
English (en)
Inventor
J Plattner Jacob
Zhang Yong-Kang
T Jacobs Robert
Original Assignee
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anacor Pharmaceuticals Inc filed Critical Anacor Pharmaceuticals Inc
Publication of MX2017012759A publication Critical patent/MX2017012759A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona, entre otros, compuestos novedosos útiles para tratar infecciones por protozoos, composiciones farmacéuticas que contienen tales compuestos, así como combinaciones de estos compuestos con al menos un agente terapéuticamente eficaz adicional. Fórmula (I) y (II).
MX2017012759A 2015-04-09 2016-04-08 Moléculas pequeñas que contienen boro como agentes antiprotozoarios. MX2017012759A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562145422P 2015-04-09 2015-04-09
US201562152605P 2015-04-24 2015-04-24
PCT/US2016/026772 WO2016164814A1 (en) 2015-04-09 2016-04-08 Boron-containing small molecules as antiprotozoal agents

Publications (1)

Publication Number Publication Date
MX2017012759A true MX2017012759A (es) 2018-05-15

Family

ID=55806821

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017012759A MX2017012759A (es) 2015-04-09 2016-04-08 Moléculas pequeñas que contienen boro como agentes antiprotozoarios.

Country Status (14)

Country Link
US (2) US10011616B2 (es)
EP (1) EP3280717A1 (es)
JP (1) JP2018514519A (es)
KR (1) KR20170136570A (es)
CN (1) CN107567456A (es)
AU (1) AU2016246802A1 (es)
BR (1) BR112017021380A2 (es)
CA (1) CA2979891A1 (es)
HK (1) HK1245277A1 (es)
IL (1) IL254770A0 (es)
MX (1) MX2017012759A (es)
RU (1) RU2017134285A (es)
SG (1) SG11201707713UA (es)
WO (1) WO2016164814A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
NZ745681A (en) 2016-03-07 2022-05-27 Agrofresh Inc Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
WO2024094235A1 (en) 2022-11-03 2024-05-10 Univerzita Karlova Use of benzoxaborole-based compounds in therapy of diseases caused by amoebas of the naegleria genus
WO2024177602A1 (en) * 2023-02-20 2024-08-29 Yeditepe Universitesi Use of boron for the treatment of leishmaniasis disease of neuronal origin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2343304T3 (en) 2005-02-16 2015-06-29 Anacor Pharmaceuticals Inc BIOCIDE BORONOPHTHALIDE COMPOUNDS
RU2008131324A (ru) * 2005-12-30 2010-02-10 Анакор Фармасьютикалз, Инк. (Us) Борсодержащие малые молекулы
WO2011017125A1 (en) * 2009-07-28 2011-02-10 Anacor Pharmaceuticals, Inc. Trisubstituted boron-containing molecules

Also Published As

Publication number Publication date
EP3280717A1 (en) 2018-02-14
IL254770A0 (en) 2017-12-31
CA2979891A1 (en) 2016-10-13
SG11201707713UA (en) 2017-10-30
CN107567456A (zh) 2018-01-09
JP2018514519A (ja) 2018-06-07
US10011616B2 (en) 2018-07-03
AU2016246802A1 (en) 2017-10-05
US20180273553A1 (en) 2018-09-27
BR112017021380A2 (pt) 2018-07-03
HK1245277A1 (zh) 2018-08-24
US20180072760A1 (en) 2018-03-15
RU2017134285A (ru) 2019-04-03
WO2016164814A1 (en) 2016-10-13
KR20170136570A (ko) 2017-12-11

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