MX2010002278A - Farmacos antivirales para el tratamiento de una infeccion por arenavirus. - Google Patents

Farmacos antivirales para el tratamiento de una infeccion por arenavirus.

Info

Publication number
MX2010002278A
MX2010002278A MX2010002278A MX2010002278A MX2010002278A MX 2010002278 A MX2010002278 A MX 2010002278A MX 2010002278 A MX2010002278 A MX 2010002278A MX 2010002278 A MX2010002278 A MX 2010002278A MX 2010002278 A MX2010002278 A MX 2010002278A
Authority
MX
Mexico
Prior art keywords
treatment
compounds
methods
antiviral drugs
hemorrhagic fever
Prior art date
Application number
MX2010002278A
Other languages
English (en)
Inventor
Dennis E Hruby
Dongcheng Dai
Tove C Bolken
Sean M Amberg
Ryan A Larson
Original Assignee
Siga Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Technologies Inc filed Critical Siga Technologies Inc
Publication of MX2010002278A publication Critical patent/MX2010002278A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se dan a conocer compuestos, métodos y composiciones farmacéuticas para tratar infecciones virales, al administrar ciertos compuestos en cantidades terapéuticamente efectivas. También se dan a conocer métodos para preparar los compuestos y métodos para utilizar los compuestos y composiciones farmacéuticas de los mismos. En particular, el tratamiento y profilaxis de infecciones virales tales como aquellas causadas por la familia de Arenavirus tales como fiebre de Lassa, fiebre hemorrágica argentina, fiebre hemorrágica boliviana y fiebre hemorrágica venezolana.
MX2010002278A 2007-08-27 2008-08-26 Farmacos antivirales para el tratamiento de una infeccion por arenavirus. MX2010002278A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93569107P 2007-08-27 2007-08-27
PCT/US2008/074328 WO2009029622A2 (en) 2007-08-27 2008-08-26 Antiviral drugs for treatment of arenavirus infection

Publications (1)

Publication Number Publication Date
MX2010002278A true MX2010002278A (es) 2010-03-17

Family

ID=40388109

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010002278A MX2010002278A (es) 2007-08-27 2008-08-26 Farmacos antivirales para el tratamiento de una infeccion por arenavirus.

Country Status (12)

Country Link
US (3) US8461177B2 (es)
EP (1) EP2182805B1 (es)
JP (1) JP5393679B2 (es)
KR (1) KR101585584B1 (es)
CN (1) CN101801189B (es)
AP (1) AP2707A (es)
AU (1) AU2008293532B2 (es)
CA (1) CA2698075C (es)
ES (1) ES2424214T3 (es)
MX (1) MX2010002278A (es)
WO (1) WO2009029622A2 (es)
ZA (1) ZA201001389B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006062898A2 (en) 2004-12-06 2006-06-15 Siga Technologies, Inc. Compounds and methods for treating hemorrhagic fever viruses
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
CA2640687A1 (en) 2006-02-01 2007-10-25 Siga Technologies, Inc. Anti-arenaviral compounds
US8791110B2 (en) 2006-02-01 2014-07-29 Siga Technologies, Inc. Anti-arenaviral compounds
US8871746B2 (en) 2006-03-02 2014-10-28 Kineta Four, LLC Antiviral drugs for treatment of arenavirus infection
US7977365B2 (en) 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US7872037B2 (en) 2006-03-02 2011-01-18 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
EP2148678A4 (en) 2007-05-23 2010-08-04 Siga Technologies Inc ANTIVIRAL DRUGS FOR THE TREATMENT AND PREVENTION OF DENGUE INFECTION
AU2008293532B2 (en) * 2007-08-27 2014-08-28 Kineta Four Llc Antiviral drugs for treatment of Arenavirus infection
MX359989B (es) * 2012-02-17 2018-10-18 Siga Tech Inc Fármacos antivirales para el tratamiento de la infección por arenavirus.
AR099283A1 (es) * 2013-11-06 2016-07-13 Celgene Corp Composiciones y métodos para el tratamiento de enfermedades virales con moduladores de la pde4
EP3198008B1 (en) * 2014-09-22 2019-05-29 Regents of the University of Minnesota Pichinde virus reverse genetics system and methods of use
US11352328B2 (en) 2016-07-12 2022-06-07 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus
KR20210125471A (ko) 2018-10-05 2021-10-18 안나푸르나 바이오, 인코포레이티드 Apj 수용체 활성과 관련된 병태를 치료하기 위한 화합물 및 조성물
CN111973598B (zh) * 2020-09-09 2021-04-13 武汉珈创生物技术股份有限公司 达拉非尼和/或其可药用衍生物在制备抗沙粒病毒药物中的应用
JP2024529298A (ja) 2021-07-09 2024-08-06 プレキシウム インコーポレイテッド Ｉｋｚｆ２を調節するアリール化合物及び医薬組成物
US12084453B2 (en) 2021-12-10 2024-09-10 Incyte Corporation Bicyclic amines as CDK12 inhibitors

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JPS527965A (en) * 1975-06-05 1977-01-21 Icn Pharmaceuticals 33deazaguanine derivatives and antiiviral and antiibacterial agent containing same
US4131735A (en) 1975-11-25 1978-12-26 Agfa-Gevaert, N.V. Preparation of α-acylacetamides using tetramethyl guanidine condensing agent
US4492708A (en) 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
US6365589B1 (en) * 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
WO2000004900A1 (en) * 1998-07-20 2000-02-03 Bristol-Myers Squibb Company Substituted benzimidazole antiviral agents
ES2254238T3 (es) * 1999-10-27 2006-06-16 Novartis Ag Compuestos de tiazol e imidazo(4,5-b)piridina y su uso farmaceutico.
HN2001000224A (es) * 2000-10-19 2002-06-13 Pfizer Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
WO2003024451A1 (de) 2001-09-08 2003-03-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg 2-(2-phenylethyl)-benzimidazol-5-carboxamid- derivative und ihre verwendung als tryptase_ inhibitoren
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
US7687641B2 (en) 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
NZ553244A (en) * 2004-07-18 2009-10-30 Csl Ltd Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses
WO2006062898A2 (en) 2004-12-06 2006-06-15 Siga Technologies, Inc. Compounds and methods for treating hemorrhagic fever viruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
CA2640687A1 (en) 2006-02-01 2007-10-25 Siga Technologies, Inc. Anti-arenaviral compounds
EP1988884A4 (en) 2006-03-02 2009-09-30 Siga Technologies Inc ANTIVIRAL DRUGS FOR THE TREATMENT OF ARENAVIRUS INFECTIONS
US7872037B2 (en) 2006-03-02 2011-01-18 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US7977365B2 (en) 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
MX348481B (es) 2007-04-23 2017-06-15 Siga Tech Inc Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
EP2148678A4 (en) 2007-05-23 2010-08-04 Siga Technologies Inc ANTIVIRAL DRUGS FOR THE TREATMENT AND PREVENTION OF DENGUE INFECTION
AU2008293532B2 (en) 2007-08-27 2014-08-28 Kineta Four Llc Antiviral drugs for treatment of Arenavirus infection
WO2009086303A2 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
CN101990434B (zh) 2008-01-15 2013-07-31 西佳技术公司 用于治疗沙粒病毒感染的抗病毒药物
MX338530B (es) 2008-06-03 2016-04-21 Siga Technologies Inc Inhibidores de molecula pequeña para el tratamiento o prevencion de infeccion de virus del dengue.

Also Published As

Publication number Publication date
US8461177B2 (en) 2013-06-11
CA2698075C (en) 2016-04-12
ZA201001389B (en) 2010-11-24
EP2182805A4 (en) 2010-12-22
US20140243367A1 (en) 2014-08-28
US20140128426A1 (en) 2014-05-08
CN101801189A (zh) 2010-08-11
JP5393679B2 (ja) 2014-01-22
EP2182805A2 (en) 2010-05-12
US20110064693A1 (en) 2011-03-17
US9096597B2 (en) 2015-08-04
KR20100080516A (ko) 2010-07-08
CN101801189B (zh) 2015-08-26
AU2008293532B2 (en) 2014-08-28
CA2698075A1 (en) 2009-03-05
US8754082B2 (en) 2014-06-17
AU2008293532A1 (en) 2009-03-05
JP2010538000A (ja) 2010-12-09
EP2182805B1 (en) 2013-06-26
ES2424214T3 (es) 2013-09-30
KR101585584B1 (ko) 2016-01-14
WO2009029622A2 (en) 2009-03-05
AP2707A (en) 2013-07-29
AP2010005172A0 (en) 2010-02-28
WO2009029622A3 (en) 2009-04-23

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