EA201001859A1 - Гетероциклические производные мочевины и способы их применеия - Google Patents

Гетероциклические производные мочевины и способы их применеия

Info

Publication number
EA201001859A1
EA201001859A1 EA201001859A EA201001859A EA201001859A1 EA 201001859 A1 EA201001859 A1 EA 201001859A1 EA 201001859 A EA201001859 A EA 201001859A EA 201001859 A EA201001859 A EA 201001859A EA 201001859 A1 EA201001859 A1 EA 201001859A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
urea
application
heterocyclic derivatives
medicines
Prior art date
Application number
EA201001859A
Other languages
English (en)
Inventor
Брайан Шерер
Фэй Чжоу
Original Assignee
Астразенека Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40848376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201001859(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Астразенека Аб filed Critical Астразенека Аб
Publication of EA201001859A1 publication Critical patent/EA201001859A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Описаны соединения формулы (I) и их фармацевтически приемлемые соли. Также описаны способы их приготовления, фармацевтические композиции, содержащие их, их применение в качестве лекарственных средств и их применение в лечении бактериальных инфекций.
EA201001859A 2008-06-04 2009-06-04 Гетероциклические производные мочевины и способы их применеия EA201001859A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5872808P 2008-06-04 2008-06-04
US15409309P 2009-02-20 2009-02-20
PCT/GB2009/050622 WO2009147440A1 (en) 2008-06-04 2009-06-04 Heterocyclic urea derivatives and methods of use thereof

Publications (1)

Publication Number Publication Date
EA201001859A1 true EA201001859A1 (ru) 2011-08-30

Family

ID=40848376

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001859A EA201001859A1 (ru) 2008-06-04 2009-06-04 Гетероциклические производные мочевины и способы их применеия

Country Status (22)

Country Link
US (1) US20090325902A1 (ru)
EP (1) EP2313402A1 (ru)
JP (1) JP2011522030A (ru)
KR (1) KR20110019737A (ru)
CN (1) CN102105468A (ru)
AR (1) AR072046A1 (ru)
AU (1) AU2009254937A1 (ru)
BR (1) BRPI0913583A2 (ru)
CA (1) CA2725572A1 (ru)
CL (1) CL2009001345A1 (ru)
CO (1) CO6351722A2 (ru)
CR (1) CR11824A (ru)
DO (1) DOP2010000374A (ru)
EA (1) EA201001859A1 (ru)
EC (1) ECSP10010659A (ru)
IL (1) IL209500A0 (ru)
MX (1) MX2010013251A (ru)
PE (1) PE20091959A1 (ru)
TW (1) TW201002728A (ru)
UY (1) UY31865A (ru)
WO (1) WO2009147440A1 (ru)
ZA (1) ZA201008609B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012010666A (es) 2010-03-31 2012-10-05 Actelion Pharmaceuticals Ltd Derivados de isoquinolin-3-ilurea antibacterianos.
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
US9120752B2 (en) 2010-07-16 2015-09-01 Purdue Pharma, L.P. Pyridine compounds as sodium channel blockers
AR088729A1 (es) 2011-03-29 2014-07-02 Actelion Pharmaceuticals Ltd Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica
AU2013203824A1 (en) 2012-03-16 2013-10-03 Purdue Pharma L.P. Substituted pyridines and pryimidines as sodium channel blockers
EP2935257B1 (en) 2012-12-20 2018-02-07 Purdue Pharma LP Cyclic sulfonamides as sodium channel blockers
CN106866571B (zh) * 2017-01-20 2018-06-29 中国药科大学 杂环脲类化合物及其药物组合物和应用
WO2018174288A1 (ja) 2017-03-24 2018-09-27 大正製薬株式会社 ２（１ｈ）－キノリノン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135953A (en) * 1984-12-28 1992-08-04 Ciba-Geigy Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals
MXPA03005298A (es) * 2000-12-15 2003-10-06 Vertex Pharma Inhibidores de girasa y usos de los mismos.
WO2006092599A2 (en) * 2005-03-04 2006-09-08 Astrazeneca Ab Pyrrole derivatives as dna gyrase and topoisomerase inhibitors
CN101627038A (zh) * 2006-12-04 2010-01-13 阿斯利康(瑞典)有限公司 抗菌多环脲化合物

Also Published As

Publication number Publication date
CL2009001345A1 (es) 2010-06-11
US20090325902A1 (en) 2009-12-31
AR072046A1 (es) 2010-08-04
CR11824A (es) 2011-01-12
MX2010013251A (es) 2010-12-21
BRPI0913583A2 (pt) 2015-10-27
IL209500A0 (en) 2011-01-31
DOP2010000374A (es) 2011-01-15
CN102105468A (zh) 2011-06-22
PE20091959A1 (es) 2010-02-13
AU2009254937A1 (en) 2009-12-10
TW201002728A (en) 2010-01-16
EP2313402A1 (en) 2011-04-27
KR20110019737A (ko) 2011-02-28
CO6351722A2 (es) 2011-12-20
ECSP10010659A (es) 2011-01-31
CA2725572A1 (en) 2009-12-10
JP2011522030A (ja) 2011-07-28
UY31865A (es) 2010-01-29
WO2009147440A1 (en) 2009-12-10
ZA201008609B (en) 2011-08-31

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