MX348481B - Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas. - Google Patents

Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.

Info

Publication number
MX348481B
MX348481B MX2014015012A MX2014015012A MX348481B MX 348481 B MX348481 B MX 348481B MX 2014015012 A MX2014015012 A MX 2014015012A MX 2014015012 A MX2014015012 A MX 2014015012A MX 348481 B MX348481 B MX 348481B
Authority
MX
Mexico
Prior art keywords
treatment
methods
chemicals
prevention
compositions
Prior art date
Application number
MX2014015012A
Other languages
English (en)
Inventor
Susan R Rippin
Dongcheng Dai
Robert Jordan
Thomas R Bailey
Original Assignee
Siga Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Tech Inc filed Critical Siga Tech Inc
Publication of MX348481B publication Critical patent/MX348481B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a métodos para utilizar derivados de acilhidrazida di-, tri- y tetracíclica y análogos, así como también composiciones farmacéuticas que contienen los mismos, para el tratamiento o profilaxis de infecciones virales y enfermedades asociadas con las mismas, particularmente aquellas infecciones virales y enfermedades asociadas que son causadas por el ortopoxvirus.
MX2014015012A 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas. MX348481B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/785,998 US8039504B2 (en) 2003-06-20 2007-04-23 Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
PCT/US2007/009751 WO2008130348A1 (en) 2007-04-23 2007-04-23 Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases

Publications (1)

Publication Number Publication Date
MX348481B true MX348481B (es) 2017-06-15

Family

ID=39876302

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2009011533A MX2009011533A (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
MX2017007471A MX363189B (es) 2007-04-23 2007-04-23 Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas.
MX2014015012A MX348481B (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2009011533A MX2009011533A (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
MX2017007471A MX363189B (es) 2007-04-23 2007-04-23 Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas.

Country Status (9)

Country Link
US (1) US8039504B2 (es)
EP (2) EP3006425A1 (es)
JP (1) JP2010535705A (es)
CN (2) CN104758281A (es)
AU (1) AU2007351866C1 (es)
CA (3) CA2866037C (es)
IL (4) IL201736A (es)
MX (3) MX2009011533A (es)
WO (1) WO2008130348A1 (es)

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US7737168B2 (en) 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7687641B2 (en) * 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8039504B2 (en) 2003-06-20 2011-10-18 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
AU2005314252B2 (en) 2004-12-06 2012-09-27 Siga Technologies, Inc. Compounds and methods for treating hemorrhagic fever viruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US8106058B2 (en) 2006-02-01 2012-01-31 Siga Technologies, Inc. Anti-arenaviral compounds
US8791110B2 (en) 2006-02-01 2014-07-29 Siga Technologies, Inc. Anti-arenaviral compounds
JP5380078B2 (ja) 2006-03-02 2014-01-08 サイガ・テクノロジーズ・インコーポレーテッド アレナウイルス感染の治療のための抗ウイルス薬剤
US8871746B2 (en) 2006-03-02 2014-10-28 Kineta Four, LLC Antiviral drugs for treatment of arenavirus infection
US7977365B2 (en) 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
WO2007100888A2 (en) 2006-03-02 2007-09-07 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
CN101034257B (zh) * 2007-04-06 2010-09-08 上海复旦天臣新技术有限公司 用于全息记录的感光薄膜及其制备方法
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ES2424214T3 (es) 2007-08-27 2013-09-30 Siga Technologies, Inc. Medicamentos antivirales para el tratamiento de una infección por Arenavirus
CN101747258B (zh) * 2008-12-04 2013-12-25 中国人民解放军军事医学科学院毒物药物研究所 N-[(3aR，4R，4aR，5aS，6S，6aS)-1，3-二氧代-3，3a，4，4a，5，5a，6，6a-八氢-4，6-亚乙烯基环丙烷[f]异氮杂茚-2(1H)-基]-4-(三氟甲基)苯甲酰胺一水合物及其医药用途
RU2412168C1 (ru) * 2009-12-02 2011-02-20 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) Гидрат n-{3,5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}-2-гидроксибензамида, обладающий противовирусной активностью в отношении ортопоксвирусов
AU2011232551B2 (en) 2010-03-23 2014-11-13 Siga Technologies, Inc Polymorphic forms ST-246 and methods of preparation
DK2600715T3 (da) * 2010-08-05 2020-03-16 Siga Tech Inc Flydende ST-246-formuleringer og fremgangsmåder
CN101906064A (zh) * 2010-08-09 2010-12-08 中国人民解放军军事医学科学院微生物流行病研究所 St-246的立体异构体的制备方法
CN101912389A (zh) * 2010-08-09 2010-12-15 中国人民解放军军事医学科学院微生物流行病研究所 含st-246的药物组合物及其制备方法与应用
RU2440983C1 (ru) * 2010-09-28 2012-01-27 Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) Метил, хлор и нитропроизводные n-{3, 5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}-2-гидроксибензамида-противовирусные препараты, ингибирующие репликацию различных видов ортопоксвирусов
CN107235890B (zh) 2012-08-16 2020-03-06 西佳技术公司 制备特考韦瑞的方法
US10406103B2 (en) 2013-11-19 2019-09-10 Siga Technologies Inc. Rehydration of micronized tecovirmimat monohydrate
AR111963A1 (es) * 2017-05-26 2019-09-04 Univ California Método y moléculas
WO2019224340A1 (en) * 2018-05-25 2019-11-28 Medimmune Limited Pyrrolobenzodiazepine conjugates
CN114150005B (zh) * 2022-02-09 2022-04-22 广州恩宝生物医药科技有限公司 用于预防SARS-CoV-2奥密克戎株的腺病毒载体疫苗
CN116003309B (zh) * 2022-08-12 2025-03-04 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用
CN116730995B (zh) * 2022-08-12 2024-06-25 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用
CN116253674A (zh) * 2023-02-06 2023-06-13 青岛增益安生物科技有限公司 制备特考韦瑞的方法
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Also Published As

Publication number Publication date
IL269370B (en) 2020-08-31
WO2008130348A1 (en) 2008-10-30
IL242666B (en) 2018-08-30
CA2866037A1 (en) 2008-10-30
CA2866037C (en) 2017-05-16
MX363189B (es) 2019-03-14
AU2007351866B2 (en) 2012-09-27
JP2010535705A (ja) 2010-11-25
MX2009011533A (es) 2010-04-07
IL269370A (en) 2019-11-28
US20070287735A1 (en) 2007-12-13
IL242665B (en) 2019-10-31
IL201736A0 (en) 2010-06-16
US8039504B2 (en) 2011-10-18
EP3006425A1 (en) 2016-04-13
AU2007351866A1 (en) 2008-10-30
CN104758281A (zh) 2015-07-08
CA2966466C (en) 2020-08-25
CN101702904A (zh) 2010-05-05
EP2148860A1 (en) 2010-02-03
AU2007351866C1 (en) 2013-07-25
EP2148860A4 (en) 2010-12-22
CA2966466A1 (en) 2008-10-30
CA2685153A1 (en) 2008-10-30
CA2685153C (en) 2014-12-16
IL201736A (en) 2016-06-30

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