MX363189B - Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas. - Google Patents

Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas.

Info

Publication number
MX363189B
MX363189B MX2017007471A MX2017007471A MX363189B MX 363189 B MX363189 B MX 363189B MX 2017007471 A MX2017007471 A MX 2017007471A MX 2017007471 A MX2017007471 A MX 2017007471A MX 363189 B MX363189 B MX 363189B
Authority
MX
Mexico
Prior art keywords
treatment
methods
chemicals
prevention
compositions
Prior art date
Application number
MX2017007471A
Other languages
English (en)
Inventor
Susan R Rippin
Robert Jordan
Thomas R Bailey
Dai Dongcheng
Original Assignee
Siga Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Tech Inc filed Critical Siga Tech Inc
Publication of MX363189B publication Critical patent/MX363189B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a métodos para utilizar derivados de acilhidrazida di-, tri- y tetracíclica y análogos, así como también composiciones farmacéuticas que contienen los mismos, para el tratamiento o profilaxis de infecciones virales y enfermedades asociadas con las mismas, particularmente aquellas infecciones virales y enfermedades asociadas que son causadas por el ortopoxvirus.
MX2017007471A 2007-04-23 2007-04-23 Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas. MX363189B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2007/009751 WO2008130348A1 (en) 2007-04-23 2007-04-23 Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US11/785,998 US8039504B2 (en) 2003-06-20 2007-04-23 Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases

Publications (1)

Publication Number Publication Date
MX363189B true MX363189B (es) 2019-03-14

Family

ID=39876302

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2014015012A MX348481B (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
MX2009011533A MX2009011533A (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
MX2017007471A MX363189B (es) 2007-04-23 2007-04-23 Productos químicos, composiciones y métodos para tratamiento y prevención de infecciones de virus orthopox y enfermedades asociadas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2014015012A MX348481B (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
MX2009011533A MX2009011533A (es) 2007-04-23 2007-04-23 Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.

Country Status (9)

Country Link
US (1) US8039504B2 (es)
EP (2) EP2148860A4 (es)
JP (1) JP2010535705A (es)
CN (2) CN101702904A (es)
AU (1) AU2007351866C1 (es)
CA (3) CA2685153C (es)
IL (4) IL201736A (es)
MX (3) MX348481B (es)
WO (1) WO2008130348A1 (es)

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US7687641B2 (en) * 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) * 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
CA2590962A1 (en) 2004-12-06 2006-06-15 Siga Technologies, Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
WO2007120374A2 (en) 2006-02-01 2007-10-25 Siga Technologies, Inc. Anti-arenaviral compounds
US8791110B2 (en) 2006-02-01 2014-07-29 Siga Technologies, Inc. Anti-arenaviral compounds
US7977365B2 (en) * 2006-03-02 2011-07-12 Siga Technologies, Inc. Antiviral drugs for treatment of arenavirus infection
US8871746B2 (en) 2006-03-02 2014-10-28 Kineta Four, LLC Antiviral drugs for treatment of arenavirus infection
AP2008004593A0 (en) 2006-03-02 2008-08-31 Siga Technologies Inc Antivral drugs for treatment of arenavirus infection
JP5380078B2 (ja) 2006-03-02 2014-01-08 サイガ・テクノロジーズ・インコーポレーテッド アレナウイルス感染の治療のための抗ウイルス薬剤
CN101034257B (zh) * 2007-04-06 2010-09-08 上海复旦天臣新技术有限公司 用于全息记录的感光薄膜及其制备方法
MX348481B (es) 2007-04-23 2017-06-15 Siga Tech Inc Productos quimicos, composiciones y metodos para tratamiento y prevencion de infecciones de virus orthopox y enfermedades asociadas.
US8518960B2 (en) 2007-05-23 2013-08-27 Siga Technologies, Inc. Antiviral drugs for treatment or prevention of dengue infection
CN101801189B (zh) 2007-08-27 2015-08-26 基内塔第四有限责任公司 用于治疗沙粒病毒感染的抗病毒药
CN101747258B (zh) * 2008-12-04 2013-12-25 中国人民解放军军事医学科学院毒物药物研究所 N-[(3aR，4R，4aR，5aS，6S，6aS)-1，3-二氧代-3，3a，4，4a，5，5a，6，6a-八氢-4，6-亚乙烯基环丙烷[f]异氮杂茚-2(1H)-基]-4-(三氟甲基)苯甲酰胺一水合物及其医药用途
KR20170102070A (ko) 2010-03-23 2017-09-06 시가 테크놀로지스, 인크. 다형체 형태 ｓｔ―２４６ 및 제조방법
US9233097B2 (en) * 2010-08-05 2016-01-12 Siga Technologies, Inc. ST-246 liquid formulations
CN101906064A (zh) * 2010-08-09 2010-12-08 中国人民解放军军事医学科学院微生物流行病研究所 St-246的立体异构体的制备方法
CN101912389A (zh) * 2010-08-09 2010-12-15 中国人民解放军军事医学科学院微生物流行病研究所 含st-246的药物组合物及其制备方法与应用
CN104540508B (zh) 2012-08-16 2017-06-20 西佳技术公司 制备特考韦瑞的方法
EP3043793B1 (en) * 2013-11-19 2021-01-06 Siga Technologies Inc. Rehydration of micronized tecovirimat monohydrate
AR111963A1 (es) * 2017-05-26 2019-09-04 Univ California Método y moléculas
US20210283141A1 (en) * 2018-05-25 2021-09-16 Medimmune Limited Pyrrolobenzodiazepine conjugates
CN114150005B (zh) * 2022-02-09 2022-04-22 广州恩宝生物医药科技有限公司 用于预防SARS-CoV-2奥密克戎株的腺病毒载体疫苗
CN116730995B (zh) * 2022-08-12 2024-06-25 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用
CN116253674A (zh) * 2023-02-06 2023-06-13 青岛增益安生物科技有限公司 制备特考韦瑞的方法
CN117582436A (zh) * 2023-08-31 2024-02-23 甫康（上海）健康科技有限责任公司 亚胺酰基酰肼类化合物、含其的组合物和其应用

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Also Published As

Publication number Publication date
JP2010535705A (ja) 2010-11-25
CA2966466A1 (en) 2008-10-30
IL269370B (en) 2020-08-31
EP2148860A4 (en) 2010-12-22
CA2685153A1 (en) 2008-10-30
CN104758281A (zh) 2015-07-08
WO2008130348A1 (en) 2008-10-30
EP3006425A1 (en) 2016-04-13
US20070287735A1 (en) 2007-12-13
IL269370A (en) 2019-11-28
AU2007351866A1 (en) 2008-10-30
CA2966466C (en) 2020-08-25
MX348481B (es) 2017-06-15
CA2685153C (en) 2014-12-16
EP2148860A1 (en) 2010-02-03
CA2866037C (en) 2017-05-16
AU2007351866B2 (en) 2012-09-27
IL201736A0 (en) 2010-06-16
AU2007351866C1 (en) 2013-07-25
IL242665B (en) 2019-10-31
CA2866037A1 (en) 2008-10-30
IL201736A (en) 2016-06-30
US8039504B2 (en) 2011-10-18
CN101702904A (zh) 2010-05-05
MX2009011533A (es) 2010-04-07
IL242666B (en) 2018-08-30

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