PA8590801A1 - Derivados de nucleosido antivirales - Google Patents

Derivados de nucleosido antivirales

Info

Publication number
PA8590801A1
PA8590801A1 PA20038590801A PA8590801A PA8590801A1 PA 8590801 A1 PA8590801 A1 PA 8590801A1 PA 20038590801 A PA20038590801 A PA 20038590801A PA 8590801 A PA8590801 A PA 8590801A PA 8590801 A1 PA8590801 A1 PA 8590801A1
Authority
PA
Panama
Prior art keywords
nucleoside derivatives
compounds
antiviral nucleoside
treatment
antiviral
Prior art date
Application number
PA20038590801A
Other languages
English (en)
Inventor
Robert Than Hendricks
Joseph Armstrong Martin
Keshab Sarma
Anthony Prince
Eric Roy Humphreys
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PA8590801A1 publication Critical patent/PA8590801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A DERIVADOS DE NUCLEOSIDO PARA EL TRATAMIENTO DE INFECCIONES DEL VIRUS DE LA HEPATITIS C INCLUYENDO LOS COMPUESTOS DE LA FORMULA I Y II, COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN ESTOS COMPUESTOS Y METODOS PARA EL TRATAMIENTO O PROFILAXIS DE ENFERMEDADES MEDIADAS DEL VIRUS DE LA HEPATITIS C QUE EMPLEAN DICHOS COMPUESTOS EN MONOTERAPIA O EN TERAPIA DE COMBINACION.
PA20038590801A 2002-12-10 2003-12-05 Derivados de nucleosido antivirales PA8590801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43210802P 2002-12-10 2002-12-10

Publications (1)

Publication Number Publication Date
PA8590801A1 true PA8590801A1 (es) 2004-11-26

Family

ID=32507851

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20038590801A PA8590801A1 (es) 2002-12-10 2003-12-05 Derivados de nucleosido antivirales

Country Status (12)

Country Link
US (1) US20040121969A1 (es)
EP (1) EP1572710A2 (es)
JP (1) JP2006510645A (es)
CN (1) CN1742018A (es)
AR (1) AR042335A1 (es)
AU (1) AU2003296601A1 (es)
CA (1) CA2508656A1 (es)
GT (1) GT200300275A (es)
PA (1) PA8590801A1 (es)
PE (1) PE20040903A1 (es)
TW (1) TW200417372A (es)
WO (1) WO2004052905A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0310593D0 (en) * 2003-05-08 2003-06-11 Leuven K U Res & Dev Peptidic prodrugs
CN1878783A (zh) * 2003-09-11 2006-12-13 弗·哈夫曼-拉罗切有限公司 制备抗病毒核苷衍生物的方法
JP2007505071A (ja) * 2003-09-11 2007-03-08 エフ．ホフマン−ラ　ロシュ　アーゲー 結晶多形性ヌクレオシド化合物
FR2869616B1 (fr) * 2004-04-29 2008-10-24 Univ D Avignon Et Des Pays Du Nouveaux composes amphiphiles, leur procede de preparation et leurs applications notamment a la transfection
WO2006031725A2 (en) * 2004-09-14 2006-03-23 Pharmasset, Inc. Preparation of 2'­fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
WO2009105258A1 (en) 2008-02-22 2009-08-27 Nektar Therapeutics Al, Corporation Oligomer conjugates of heteropentacyclic nucleosides
EP2113508A1 (en) * 2008-04-30 2009-11-04 INSERM (Institut National de la Santé et de la Recherche Medicale) Novel triazole nucleoside derivatives, their preparation and their application in therapeutics
TW201031675A (en) 2008-12-23 2010-09-01 Pharmasset Inc Synthesis of purine nucleosides
JP6824062B2 (ja) * 2017-02-14 2021-02-03 日本電子株式会社 イオン化法選択支援装置及び方法
WO2018230479A1 (ja) * 2017-06-13 2018-12-20 大原薬品工業株式会社 ヌクレオシド系抗がん剤又は抗ウィルス剤の５'位シリルエーテル誘導体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998807A (en) * 1972-03-03 1976-12-21 Syntex (U.S.A.) Inc. Arabinofuranosyl cytosines and methods of making
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
IE980216A1 (en) * 1989-04-17 2000-02-23 Scotia Holdings Plc Anti-virals
US6184376B1 (en) * 1997-02-10 2001-02-06 Mediver Ab Synthesis of acyclic nucleoside derivatives
US6277830B1 (en) * 1998-10-16 2001-08-21 Schering Corporation 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
US6518253B1 (en) * 1999-11-19 2003-02-11 Robert Tam Treatment of viral infections using the L-isomer of ribavirin
US6495677B1 (en) * 2000-02-15 2002-12-17 Kanda S. Ramasamy Nucleoside compounds

Also Published As

Publication number Publication date
AU2003296601A1 (en) 2004-06-30
US20040121969A1 (en) 2004-06-24
CN1742018A (zh) 2006-03-01
GT200300275A (es) 2004-06-28
TW200417372A (en) 2004-09-16
EP1572710A2 (en) 2005-09-14
AU2003296601A8 (en) 2004-06-30
JP2006510645A (ja) 2006-03-30
WO2004052905A3 (en) 2004-10-14
PE20040903A1 (es) 2004-12-02
CA2508656A1 (en) 2004-06-24
AR042335A1 (es) 2005-06-15
WO2004052905A2 (en) 2004-06-24

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