MX2021006156A - Compuestos utiles en la terapia para el vih. - Google Patents

Compuestos utiles en la terapia para el vih.

Info

Publication number
MX2021006156A
MX2021006156A MX2021006156A MX2021006156A MX2021006156A MX 2021006156 A MX2021006156 A MX 2021006156A MX 2021006156 A MX2021006156 A MX 2021006156A MX 2021006156 A MX2021006156 A MX 2021006156A MX 2021006156 A MX2021006156 A MX 2021006156A
Authority
MX
Mexico
Prior art keywords
compounds useful
hiv therapy
compounds
hiv
therapy
Prior art date
Application number
MX2021006156A
Other languages
English (en)
Inventor
David Margolis
La Rosa Martha Alicia De
Richard M Dunham
Vincent Wing-Fai Tai
Jun Tang
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of MX2021006156A publication Critical patent/MX2021006156A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención se refiere a compuestos de fórmula (I), (Ia), (Ib), (II) o (III), sales de los mismos, a composiciones farmacéuticas de los mismos, así como a procedimientos terapéuticos de tratamiento y prevención.
MX2021006156A 2018-11-30 2019-11-28 Compuestos utiles en la terapia para el vih. MX2021006156A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862773563P 2018-11-30 2018-11-30
PCT/IB2019/060267 WO2020110056A1 (en) 2018-11-30 2019-11-28 Compounds useful in hiv therapy

Publications (1)

Publication Number Publication Date
MX2021006156A true MX2021006156A (es) 2021-09-08

Family

ID=68808475

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2021006156A MX2021006156A (es) 2018-11-30 2019-11-28 Compuestos utiles en la terapia para el vih.
MX2023014492A MX2023014492A (es) 2018-11-30 2021-05-26 Compuestos utiles en la terapia para el vih.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023014492A MX2023014492A (es) 2018-11-30 2021-05-26 Compuestos utiles en la terapia para el vih.

Country Status (15)

Country Link
EP (2) EP3886987B1 (es)
JP (2) JP7406556B2 (es)
KR (1) KR20210097154A (es)
CN (1) CN113613724A (es)
AR (1) AR117206A1 (es)
AU (1) AU2019390729B2 (es)
BR (1) BR112021010353A2 (es)
CA (1) CA3121140A1 (es)
CL (1) CL2021001388A1 (es)
ES (1) ES2968538T3 (es)
IL (2) IL310831A (es)
MX (2) MX2021006156A (es)
TW (1) TWI824069B (es)
WO (1) WO2020110056A1 (es)
ZA (1) ZA202103349B (es)

Families Citing this family (7)

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US11466017B2 (en) 2011-03-10 2022-10-11 Board Of Regents, The University Of Texas System Heterocyclic inhibitors of PTPN11
AU2017274199B2 (en) 2016-05-31 2021-09-23 Board Of Regents, The University Of Texas System Heterocyclic inhibitors of PTPN11
WO2019213318A1 (en) 2018-05-02 2019-11-07 Board Of Regents, The University Of Texas System Substituted heterocyclic inhibitors of ptpn11
JP2021534124A (ja) 2018-08-10 2021-12-09 ナビール ファーマ，インコーポレイティド 癌治療用ｐｔｐｎ１１（ｓｈｐ２）阻害剤としての６−（４−アミノ−３−メチル−２−オキサ−８−アザスピロ［４．５］デカン−８−イル）−３−（２，３−ジクロロフェニル）−２−メチルピリミジン−４（３ｈ）−オン誘導体及び関連化合物
TW202039426A (zh) 2018-11-30 2020-11-01 美商彗星製藥公司 泛硫醇（Ｐａｎｔｅｔｈｅｉｎｅ）衍生物及其用途
CA3160666A1 (en) * 2019-11-08 2021-05-14 Sanford Burnham Prebys Medical Discovery Institute Inhibitor of apoptosis (iap) protein antagonists
US20240173276A1 (en) * 2021-03-23 2024-05-30 The University Of North Carolina At Chapel Hill Methods and compositions for inhibiting formation of the hiv latent reservoir

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Also Published As

Publication number Publication date
EP3886987A1 (en) 2021-10-06
IL283487A (en) 2021-07-29
JP7406556B2 (ja) 2023-12-27
TW202039514A (zh) 2020-11-01
AR117206A1 (es) 2021-07-21
WO2020110056A1 (en) 2020-06-04
TWI824069B (zh) 2023-12-01
BR112021010353A2 (pt) 2021-08-31
CL2021001388A1 (es) 2021-11-05
CA3121140A1 (en) 2020-06-04
JP2022509869A (ja) 2022-01-24
EP3886987C0 (en) 2023-11-15
EP3886987B1 (en) 2023-11-15
IL283487B1 (en) 2024-03-01
EP4342473A2 (en) 2024-03-27
ZA202103349B (en) 2022-12-21
KR20210097154A (ko) 2021-08-06
AU2019390729A1 (en) 2021-06-03
IL310831A (en) 2024-04-01
EP4342473A3 (en) 2024-05-15
IL283487B2 (en) 2024-07-01
CN113613724A (zh) 2021-11-05
JP2024023259A (ja) 2024-02-21
ES2968538T3 (es) 2024-05-10
MX2023014492A (es) 2024-01-25
AU2019390729B2 (en) 2022-08-11

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