ATE254632T1 - Neue salzformn von (2e)-5-amino-5-methylhex-2- enolsäure n-methyl-n-((1r)-1-(methylcarbamoyl)-2- phruylrthyl) carbamoyl)-2-(2-naphtyl)ethyl)amid - Google Patents
Neue salzformn von (2e)-5-amino-5-methylhex-2- enolsäure n-methyl-n-((1r)-1-(methylcarbamoyl)-2- phruylrthyl) carbamoyl)-2-(2-naphtyl)ethyl)amidInfo
- Publication number
- ATE254632T1 ATE254632T1 AT99937933T AT99937933T ATE254632T1 AT E254632 T1 ATE254632 T1 AT E254632T1 AT 99937933 T AT99937933 T AT 99937933T AT 99937933 T AT99937933 T AT 99937933T AT E254632 T1 ATE254632 T1 AT E254632T1
- Authority
- AT
- Austria
- Prior art keywords
- methyl
- methylcarbamoyl
- carbamoyl
- ethyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK28298 | 1998-03-03 | ||
PCT/DK1999/000089 WO1999045029A1 (en) | 1998-03-03 | 1999-02-26 | New salt forms of (2e)- 5-amino-5- methylhex-2- enoic acid n-methyl-n-((1r)-1-(n- methyl-n-((1r)-1-(methylcarbamoyl)-2- phenylethyl)carbamoyl)-2- (2-naphtyl)ethyl)amide |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE254632T1 true ATE254632T1 (de) | 2003-12-15 |
Family
ID=8091813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99937933T ATE254632T1 (de) | 1998-03-03 | 1999-02-26 | Neue salzformn von (2e)-5-amino-5-methylhex-2- enolsäure n-methyl-n-((1r)-1-(methylcarbamoyl)-2- phruylrthyl) carbamoyl)-2-(2-naphtyl)ethyl)amid |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1060190B1 (de) |
JP (1) | JP2002505340A (de) |
KR (1) | KR20010041533A (de) |
CN (1) | CN1291994A (de) |
AT (1) | ATE254632T1 (de) |
AU (1) | AU3247899A (de) |
BR (1) | BR9908399A (de) |
CA (1) | CA2322051A1 (de) |
DE (1) | DE69912930D1 (de) |
HU (1) | HUP0100998A3 (de) |
IL (1) | IL137353A0 (de) |
PL (1) | PL342706A1 (de) |
TW (1) | TW538047B (de) |
WO (1) | WO1999045029A1 (de) |
ZA (1) | ZA991572B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1407779A1 (de) | 2002-10-10 | 2004-04-14 | Gastrotech A/S | Verwendung von Ghrelin zur Behandlung von vermindertem Körpergewicht und Körperfett in Individuen mit Gastrektomie |
US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
CN101657436A (zh) | 2007-02-09 | 2010-02-24 | 特兰齐姆制药公司 | 大环生长素释放肽受体调节剂及其使用方法 |
PL2480559T3 (pl) | 2009-09-21 | 2013-11-29 | Gilead Sciences Inc | Sposoby i związki pośrednie do wytwarzania analogów 11cyjanokarbanukleozydowych |
WO2012012465A1 (en) | 2010-07-19 | 2012-01-26 | Clarke, Michael, O'neil Hanrahan | Methods for the preparation of diasteromerically pure phosphoramidate prodrugs |
CN103052631B (zh) | 2010-07-22 | 2015-11-25 | 吉里德科学公司 | 用于治疗副黏病毒科病毒感染的方法和化合物 |
TWI687432B (zh) | 2014-10-29 | 2020-03-11 | 美商基利科學股份有限公司 | 絲狀病毒科病毒感染之治療 |
EP3242934B1 (de) | 2015-01-08 | 2021-08-18 | The Board of Trustees of the Leland Stanford Junior University | Faktoren und zellen zur bereitstellung der induktion von knochen, knochenmark und knorpel |
DK3785717T3 (da) | 2015-09-16 | 2022-03-21 | Gilead Sciences Inc | Fremgangsmåder til behandling af coronaviridae-infektioner |
JP6824434B2 (ja) | 2017-03-14 | 2021-02-03 | ギリアード サイエンシーズ, インコーポレイテッド | ネココロナウイルス感染を処置する方法 |
EP4219513A1 (de) | 2017-05-01 | 2023-08-02 | Gilead Sciences, Inc. | Kristalline form von (s)-2-ethylbutyl 2-((s)-(((2r,3s,4r,5r)-5-(4-aminopyrrolo[2,1-f) [1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran2-yl)methoxy)oat |
CN111093627B (zh) | 2017-07-11 | 2024-03-08 | 吉利德科学公司 | 用于治疗病毒感染的包含rna聚合酶抑制剂和环糊精的组合物 |
CN114641299A (zh) | 2020-01-27 | 2022-06-17 | 吉利德科学公司 | 用于治疗SARS CoV-2感染的方法 |
AU2021234308C1 (en) | 2020-03-12 | 2024-02-22 | Gilead Sciences, Inc. | Methods of preparing 1'-cyano nucleosides |
CA3172483A1 (en) | 2020-04-06 | 2021-10-14 | Scott Ellis | Inhalation formulations of 1'-cyano substituted carbanucleoside analogs |
TW202203941A (zh) | 2020-05-29 | 2022-02-01 | 美商基利科學股份有限公司 | 瑞德西韋之治療方法 |
CA3187821A1 (en) | 2020-06-24 | 2021-12-30 | Gilead Sciences, Inc. | 1'-cyano nucleoside analogs and uses thereof |
TW202233204A (zh) | 2020-08-27 | 2022-09-01 | 美商基利科學股份有限公司 | 用於治療病毒感染之化合物及方法 |
EP4320128A1 (de) | 2022-03-02 | 2024-02-14 | Gilead Sciences, Inc. | Verbindungen und verfahren zur behandlung von virusinfektionen |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69637855D1 (de) * | 1995-12-22 | 2009-04-16 | Novo Nordisk As | Verbindungen mit wachstumshormon-freisetzenden eigenschaften |
-
1999
- 1999-02-26 JP JP2000534571A patent/JP2002505340A/ja active Pending
- 1999-02-26 AT AT99937933T patent/ATE254632T1/de not_active IP Right Cessation
- 1999-02-26 DE DE69912930T patent/DE69912930D1/de not_active Expired - Lifetime
- 1999-02-26 HU HU0100998A patent/HUP0100998A3/hu unknown
- 1999-02-26 IL IL13735399A patent/IL137353A0/xx unknown
- 1999-02-26 ZA ZA9901572A patent/ZA991572B/xx unknown
- 1999-02-26 KR KR1020007009706A patent/KR20010041533A/ko not_active Application Discontinuation
- 1999-02-26 WO PCT/DK1999/000089 patent/WO1999045029A1/en not_active Application Discontinuation
- 1999-02-26 EP EP99937933A patent/EP1060190B1/de not_active Expired - Lifetime
- 1999-02-26 AU AU32478/99A patent/AU3247899A/en not_active Abandoned
- 1999-02-26 CA CA002322051A patent/CA2322051A1/en not_active Abandoned
- 1999-02-26 BR BR9908399-0A patent/BR9908399A/pt not_active IP Right Cessation
- 1999-02-26 CN CN99803429A patent/CN1291994A/zh active Pending
- 1999-02-26 PL PL99342706A patent/PL342706A1/xx not_active Application Discontinuation
- 1999-03-30 TW TW088105002A patent/TW538047B/zh active
Also Published As
Publication number | Publication date |
---|---|
AU3247899A (en) | 1999-09-20 |
DE69912930D1 (de) | 2003-12-24 |
JP2002505340A (ja) | 2002-02-19 |
TW538047B (en) | 2003-06-21 |
HUP0100998A3 (en) | 2001-12-28 |
CN1291994A (zh) | 2001-04-18 |
CA2322051A1 (en) | 1999-09-10 |
BR9908399A (pt) | 2000-10-31 |
KR20010041533A (ko) | 2001-05-25 |
ZA991572B (en) | 1999-09-03 |
IL137353A0 (en) | 2001-07-24 |
WO1999045029A1 (en) | 1999-09-10 |
PL342706A1 (en) | 2001-07-02 |
EP1060190A1 (de) | 2000-12-20 |
HUP0100998A2 (hu) | 2001-08-28 |
EP1060190B1 (de) | 2003-11-19 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |